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17 Dec - 18 Dec
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18 Dec - 19 Dec
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19 Dec - 21 Dec
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26 Dec - 28 Dec

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Our top choices for Ensanche Quisqueya hotels

Apartment, 3 Bedrooms | Living room
Apartment Silvestre

Apartment Silvestre

Apartment Silvestre
3.5 star property
Ensanche Quisqueya
The price is 13.156.000 ₫
15.524.080 ₫ total
includes taxes & fees
26 Dec - 27 Dec
Apartment Silvestre
Restaurant
Homewood Suites by Hilton Santo Domingo, Dominican Republic

Homewood Suites by Hilton Santo Domingo, Dominican Republic

Homewood Suites by Hilton Santo Domingo, Dominican Republic
3.5 star property
Ensanche Quisqueya
9.4 out of 10, Exceptional, (703)
"Good place to stay , close to the blue mall "
United States
Fernando
The price is 3.214.800 ₫
4.114.944 ₫ total
includes taxes & fees
16 Jan - 17 Jan 2026
Homewood Suites by Hilton Santo Domingo, Dominican Republic
Exterior
Casas del XVI

Casas del XVI

Casas del XVI
5.0 star property
5.7 km from Ensanche Quisqueya
9.4 out of 10, Exceptional, (229)
"Everything was amazing "
United States
Lesterlin
The price is 7.407.844 ₫
9.482.040 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Casas del XVI
Outdoor spa tub
Luca Hotel by Heritage Residences Signature Collection

Luca Hotel by Heritage Residences Signature Collection

Luca Hotel by Heritage Residences Signature Collection
3.5 star property
Ciudad Colonial, 6.2 km from Ensanche Quisqueya
9.2 out of 10, Wonderful, (701)
"Great staff, clean and comfortable An rooms"
United States
Asfaha
Luca Hotel by Heritage Residences Signature Collection
Lobby
Hodelpa Nicolas de Ovando

Hodelpa Nicolas de Ovando

Hodelpa Nicolas de Ovando
4.5 star property
Ciudad Colonial, 6.6 km from Ensanche Quisqueya
9.2 out of 10, Wonderful, (1000)
"The food was excellent and well presented and the staff was pleasant and very helpful."
United States
William
The price is 5.215.122 ₫
6.675.356 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Hodelpa Nicolas de Ovando
Outdoor pool
Boutique Hotel Casa Grande, Dominican Voyage Familiar Suite, 2 BR

Boutique Hotel Casa Grande, Dominican Voyage Familiar Suite, 2 BR

Boutique Hotel Casa Grande, Dominican Voyage Familiar Suite, 2 BR
4.0 star property
Ciudad Colonial, 6 km from Ensanche Quisqueya
10.0 out of 10, Exceptional, (1)
"Clean, quite with someone at front dest 24/7. Santa Dominga is not the typicalspot but a great sovacation "
United States
Charles
The price is 5.519.994 ₫
6.513.593 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Boutique Hotel Casa Grande, Dominican Voyage Familiar Suite, 2 BR
Terrace/patio
Hampton by Hilton Santo Domingo Airport

Hampton by Hilton Santo Domingo Airport

Hampton by Hilton Santo Domingo Airport
3.5 star property
29.5 km from Ensanche Quisqueya
9.2 out of 10, Wonderful, (1002)
"Great hotel clean and close to airport"
United States
David
The price is 3.171.648 ₫
4.059.710 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Hampton by Hilton Santo Domingo Airport
Exterior
Mosquito Boutique Hotel Zona Colonial

Mosquito Boutique Hotel Zona Colonial

Mosquito Boutique Hotel Zona Colonial
3.5 star property
Ciudad Colonial, 6.4 km from Ensanche Quisqueya
8.8 out of 10, Excellent, (256)
"Amazing services on our stay. "
United States
Gilbert
The price is 2.341.768 ₫
2.997.463 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
Mosquito Boutique Hotel Zona Colonial
Owner´s Flat | Living area | LED TV, tablet, iPod dock
Billini Hotel, Historic Luxury

Billini Hotel, Historic Luxury

Billini Hotel, Historic Luxury
4.5 star property
Ciudad Colonial, 6.1 km from Ensanche Quisqueya
9.2 out of 10, Wonderful, (806)
"Great "
United States
Steven
The price is 5.446.584 ₫
6.971.628 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Billini Hotel, Historic Luxury
Outdoor pool, pool umbrellas, pool loungers
Central Suites Tower

Central Suites Tower

Central Suites Tower
4.5 star property
Lope De Vega, 2.2 km from Ensanche Quisqueya
8.8 out of 10, Excellent, (76)
"Great Hotel, very fancy looking "
United States
Gil
The price is 2.546.401 ₫
3.004.753 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Central Suites Tower
Property amenity
El Embajador, a Royal Hideaway Hotel

El Embajador, a Royal Hideaway Hotel

El Embajador, a Royal Hideaway Hotel
5.0 star property
Bella Vista, 1.5 km from Ensanche Quisqueya
9.2 out of 10, Wonderful, (1288)
"Great stay "
United States
Nelson
The price is 2.634.229 ₫
3.371.813 ₫ total
includes taxes & fees
25 Dec - 26 Dec
El Embajador, a Royal Hideaway Hotel
Standard Double or Twin Room, Sea View | Minibar, in-room safe, desk, blackout curtains
Napolitano Hotel

Napolitano Hotel

Napolitano Hotel
3.0 star property
5.6 km from Ensanche Quisqueya
7.6 out of 10, Good, (876)
"Rooms and bathroom very clean the hotel very clean the staff 👌 security 👌 8 out of 10 for the price "
United States
Ruddy
Napolitano Hotel
Comfort Room | In-room safe, desk, iron/ironing board, free WiFi
El Beaterio

El Beaterio

El Beaterio
3.0 star property
Ciudad Colonial, 6.3 km from Ensanche Quisqueya
9.2 out of 10, Wonderful, (420)
"A great stay in a spiritual space built in 1525. "
United States
Edgardo
The price is 2.674.989 ₫
3.423.985 ₫ total
includes taxes & fees
31 Dec - 1 Jan 2026
El Beaterio
Outdoor pool, pool umbrellas, pool loungers
Sheraton Santo Domingo Hotel

Sheraton Santo Domingo Hotel

Sheraton Santo Domingo Hotel
4.0 star property
Gascue, 4.9 km from Ensanche Quisqueya
8.8 out of 10, Excellent, (1004)
"Quick stopover, clean rooms. Kind staff"
United Kingdom
Greg
The price is 2.844.612 ₫
3.641.104 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Sheraton Santo Domingo Hotel
Front of property
Boutique Hotel Palacio

Boutique Hotel Palacio

Boutique Hotel Palacio
3.5 star property
Ciudad Colonial, 6.3 km from Ensanche Quisqueya
8.6 out of 10, Excellent, (1000)
"It is a great hotel"
United States
Linda
The price is 1.973.400 ₫
2.525.952 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
Boutique Hotel Palacio
Superior Premium Level Room | Room amenity
Barceló Santo Domingo

Barceló Santo Domingo

Barceló Santo Domingo
4.0 star property
Miraflores, 3.7 km from Ensanche Quisqueya
8.6 out of 10, Excellent, (1363)
"Great Food "
United States
Juana
The price is 1.480.050 ₫
1.894.464 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Barceló Santo Domingo
Outdoor pool
Kimpton Las Mercedes by IHG

Kimpton Las Mercedes by IHG

Kimpton Las Mercedes by IHG
4.5 star property
Ciudad Colonial, 6.3 km from Ensanche Quisqueya
9.6 out of 10, Exceptional, (147)
"Beautiful hotel, great staff, wonderful stay. highly recommend! "
United States
Adam
The price is 5.004.410 ₫
6.405.645 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Kimpton Las Mercedes by IHG
Outdoor pool, open 7:00 AM to 9:00 PM, pool loungers
Embassy Suites by Hilton Santo Domingo

Embassy Suites by Hilton Santo Domingo

Embassy Suites by Hilton Santo Domingo
4.0 star property
2.3 km from Ensanche Quisqueya
9.4 out of 10, Exceptional, (1006)
"Great hotel to stay, loved it!"
United States
Nelson
The price is 3.788.928 ₫
4.849.827 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Embassy Suites by Hilton Santo Domingo
Outdoor pool, pool loungers
Four Points by Sheraton Santo Domingo

Four Points by Sheraton Santo Domingo

Four Points by Sheraton Santo Domingo
4.0 star property
25.2 km from Ensanche Quisqueya
8.2 out of 10, Very good, (182)
"Everything was really good for the price"
United States
Adrian
The price is 3.762.616 ₫
4.816.149 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Four Points by Sheraton Santo Domingo
Deluxe Apartment | Living area
Shalom Residences By YellowKey

Shalom Residences By YellowKey

Shalom Residences By YellowKey
2.5 star property
1.4 km from Ensanche Quisqueya
8.8 out of 10, Excellent, (3)
"Good location, nice building with covered parking. Communication could be better. There was a bit of confusion with the check in and the phone number provided thru Expedia was never answered, and on Whattsapp they replied hours later. Apartment is tiny but cute.. Nice stay in general. "
United States
VIVIANA
The price is 1.975.425 ₫
3.516.256 ₫ total
includes taxes & fees
20 Dec - 21 Dec
Shalom Residences By YellowKey
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Ensanche Quisqueya

Find the best Ensanche Quisqueya areas for the activities you enjoy most.
Fort Ozama which includes heritage elements

Zona Colonial

Zona Colonial is popular for its abundant dining options, and if you're looking for more to see and do, you might think about a trip to Calle El Conde or Santa Maria la Menor Cathedral.

Downtown Santo Domingo

Consider exploring the abundant dining options in Downtown Santo Domingo. If sightseeing is on the list, Acropolis Center is a top attraction. Hop on the metro at Freddy Beras Goico Station or Juan Ulises Garcia Station to see more of the area.

Piantini

Unique features of Piantini include the shopping and restaurants. Make a stop by Blue Mall or Acropolis Center while you're exploring the area.

Alcazar de Colon showing a square or plaza and a city

Ciudad Colonial

If you're spending some time in Ciudad Colonial, Calle El Conde and Santa Maria la Menor Cathedral are top sights worth seeing.

Bella Vista

While there might not be top attractions in Bella Vista, you can explore the larger area and discover places like Acropolis Center and Bella Vista Mall.

Top Ensanche Quisqueya Hotel Reviews

Frequently asked questions

What's it like in Ensanche Quisqueya?
Travellers will be sure to find plenty to entertain them in Santo Domingo's Ensanche Quisqueya neighbourhood. Consider a visit to Gate of San Diego as part of your Ensanche Quisqueya travel plans.
How many hotels will I be able to find in Ensanche Quisqueya?
If you're searching for places to stay in Santo Domingo, Expedia has something to meet your needs with 73 Ensanche Quisqueya hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Ensanche Quisqueya, will I receive a refund?
Yes, most hotel bookings are refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to review the best deals in Ensanche Quisqueya.
What are the top things to see and do in Ensanche Quisqueya?
Gate of San Diego is an attraction you might want to check out while you're in Ensanche Quisqueya. Acropolis Center and Caribbean Cinemas Acrópolis Center are also worth a visit when you're out sightseeing in Santo Domingo.