A calm lake surrounded by trees with autumn foliage.

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Check prices for these dates

This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

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Our top choices for Florence, SC (FLO-Florence Regional) hotels

A spacious lobby with a checkered floor, a reception desk, and a chandelier.

1. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
8 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (2,746 reviews)
"A convenient stop for travelers to rest."
United States
Alanda
The price is 1.671.590 ₫
1.872.182 ₫ total
includes taxes & fees
22 Oct - 23 Oct
Howard Johnson by Wyndham Florence
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.

2. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
8 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (2,477 reviews)
"Clean room, the breakfast was great!"
United States
Juan
The price is 2.335.309 ₫
2.615.545 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Park Inn by Radisson Florence, SC
A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.

3. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
3.0 star property
3.5 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (1,006 reviews)
"Clean room and excellent staff. The breakfast is really good."
United States
JEFFREY
The price is 2.587.600 ₫
2.898.112 ₫ total
includes taxes & fees
9 Nov - 10 Nov
Hyatt Place Florence Downtown
A hotel lobby with a reception desk, seating area, and a television screen.

4. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
9.6 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (1,374 reviews)
"Breakfast was excellent. Room was clean and quiet."
United States
Mila
The price is 2.617.357 ₫
2.931.439 ₫ total
includes taxes & fees
11 Nov - 12 Nov
Comfort Inn & Suites Florence Center Area
A hotel room with two beds, a desk with a TV, and a bathroom visible through an open door.

5. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
2.5 star property
8.3 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (1,001 reviews)
"Good location- very good free breakfast"
United States
Christopher
The price is 3.156.872 ₫
3.791.870 ₫ total
includes taxes & fees
25 Oct - 26 Oct
Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.

6. Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
2.5 star property
8.2 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (995 reviews)
"Great location and great rooms. We were definitely pleased with our stay."
United States
Ladavish
The price is 3.167.222 ₫
3.547.289 ₫ total
includes taxes & fees
28 Oct - 29 Oct
Hampton Inn & Suites Florence-North-I-95
A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.

7. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
8 km from Florence, SC (FLO-Florence Regional)
8.4 out of 10, Very good, (333 reviews)
"The staff was great and the room was clean! Great pit stop on our way to Disney!"
United States
Tienia
The price is 2.507.384 ₫
2.910.479 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Spark by Hilton Florence North I-95, SC
A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.

8. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
3.0 star property
9.7 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (917 reviews)
"The staff was amazing!!! The rooms are impeccable the kitchen is excellent!!! I would love to stay here every time"
United States
Crystal
The price is 2.837.303 ₫
3.177.781 ₫ total
includes taxes & fees
1 Nov - 2 Nov
TownePlace Suites by Marriott Florence
A hotel entrance with a stone facade, glass doors, and a number '501' above.

9. Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
3.0 star property
9.6 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (660 reviews)
"I enjoyed a two night stay here at Fairfield. The staff was completely awesome. The breakfast was amazing, so many options to choose from to meet every healthy meal plan. The amenities were very clean, modern and chic, providing an upscale experience. Overall experience was excellent!"
United States
Alma
The price is 3.059.849 ₫
3.427.031 ₫ total
includes taxes & fees
25 Oct - 26 Oct
Fairfield Inn & Suites by Marriott Florence I-20
An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.

10. Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
8.4 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (1,000 reviews)
"Great hotel and staff"
United States
Margarita
The price is 2.837.303 ₫
3.331.741 ₫ total
includes taxes & fees
28 Oct - 29 Oct
Tru by Hilton Florence I-95
A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.

11. Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
3.0 star property
10.7 km from Florence, SC (FLO-Florence Regional)
9.4 out of 10, Exceptional, (1,000 reviews)
"Enjoyed our stay."
United States
Tishia
The price is 3.392.638 ₫
3.799.755 ₫ total
includes taxes & fees
15 Nov - 16 Nov
Staybridge Suites Florence - Civic Center by IHG
A hotel room with a desk, chair, bed, and a yellow sofa.

12. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
2.5 star property
10.2 km from Florence, SC (FLO-Florence Regional)
8.4 out of 10, Very good, (403 reviews)
"Nice spot for an overnight!"
United States
Sharhonda
The price is 2.305.552 ₫
2.582.219 ₫ total
includes taxes & fees
28 Oct - 29 Oct
Quality Inn & Suites Florence Civic Center
A spacious lobby with a high ceiling, a central seating area, and a staircase leading to an upper level.

13. La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
3.0 star property
8.1 km from Florence, SC (FLO-Florence Regional)
7.8 out of 10, Good, (1,475 reviews)
"Great Staff, room clean and Relaxing"
United States
LaShanda
The price is 2.214.279 ₫
2.480.251 ₫ total
includes taxes & fees
25 Oct - 26 Oct
La Quinta Inn & Suites by Wyndham Florence
A restaurant with brick walls, framed awards, and a bar area.

14. Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
3.0 star property
3.6 km from Florence, SC (FLO-Florence Regional)
8.8 out of 10, Excellent, (658 reviews)
"Beautifully located hotel with plenty of restaurants and bars around. The room was super large and well taken care. Definitely recommended"
United States
Ankh
The price is 3.588.945 ₫
4.019.618 ₫ total
includes taxes & fees
30 Oct - 31 Oct
Hotel Florence, Tapestry Collection by Hilton
A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.

15. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
2.5 star property
10.7 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (1,000 reviews)
"Wonderful hotel and in a great location!"
United States
Leigh
The price is 2.949.864 ₫
3.303.848 ₫ total
includes taxes & fees
25 Oct - 26 Oct
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.

16. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
2.5 star property
9.9 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (990 reviews)
"Very enjoyable stay"
United States
William
The price is 2.947.276 ₫
3.300.950 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Hampton Inn & Suites Florence Center
A spacious lobby with a reception desk, seating area, and large windows.

17. Hilton Garden Inn Florence

Hilton Garden Inn Florence
2.5 star property
9.9 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (356 reviews)
"Rooms were clean and staff was friendly."
United States
Derrick
The price is 3.059.849 ₫
3.427.030 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Hilton Garden Inn Florence
A spacious lobby with a high ceiling, a central seating area with armchairs and a coffee table, a flat-screen TV, and a dining area with tables and chairs.

18. Residence Inn Marriott Florence

Residence Inn Marriott Florence
3.0 star property
9.9 km from Florence, SC (FLO-Florence Regional)
8.8 out of 10, Excellent, (585 reviews)
"The room was clean and spacious. The staff was friendly."
United States
Teri
The price is 2.776.266 ₫
3.109.417 ₫ total
includes taxes & fees
8 Nov - 9 Nov
Residence Inn Marriott Florence
Terrace/patio

19. Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC
3.0 star property
10.4 km from Florence, SC (FLO-Florence Regional)
8.4 out of 10, Very good, (1,001 reviews)
"Great for families"
United States
saleh
The price is 2.947.276 ₫
3.454.913 ₫ total
includes taxes & fees
15 Nov - 16 Nov
Home2 Suites by Hilton Florence, SC
A modern lobby with seating areas, a reception desk, and a large wall with a decorative panel.

20. Comfort Suites Florence I-95

Comfort Suites Florence I-95
2.5 star property
8.3 km from Florence, SC (FLO-Florence Regional)
8.2 out of 10, Very good, (1,001 reviews)
"Great area and nice hotel!"
United States
Jennifer
The price is 2.589.800 ₫
3.158.261 ₫ total
includes taxes & fees
16 Nov - 17 Nov
Comfort Suites Florence I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Florence, SC (FLO-Florence Regional)

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A spacious lobby with a checkered floor, a reception desk, and a chandelier.
Howard Johnson by Wyndham Florence
2.0 star property
8.6
Excellent
2,746 reviews
View
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.
Park Inn by Radisson Florence, SC
2.5 star property
9.0
Wonderful
2,477 reviews
View
A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.
Hyatt Place Florence Downtown
3.0 star property
9.0
Wonderful
1,006 reviews
View
A hotel lobby with a reception desk, seating area, and a television screen.
Comfort Inn & Suites Florence Center Area
2.5 star property
9.0
Wonderful
1,374 reviews
View
A hotel room with two beds, a desk with a TV, and a bathroom visible through an open door.
Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
2.5 star property
8.6
Excellent
1,001 reviews
View

Top Florence Regional Hotel Reviews

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

10/10 Excellent
"The staff was amazing, went over and beyond the call of customer service. Everything was reasonably priced especially with all that is offered with the hotel and the surrounding area."
Katie 1-night trip
Posted 1 day ago
Hyatt Place Florence Downtown

Guide to exploring Florence Regional

Florence Regional hotels information

Number of reviews
12,887
Accommodation
134 hotels
Lowest Price
1.872.182 ₫
Highest Price
4.019.618 ₫

Frequently asked questions

What's the area like near Florence, SC (FLO-Florence Regional)?

Florence, SC (FLO-Florence Regional) is located in a welcoming area of Florence known for its array of dining options. You'll find 72 hotels and other accommodations within a few miles of the airport for a convenient home base.

How many hotels can I expect to find close to Florence, SC (FLO-Florence Regional)?

Expedia has 72 hotels and other accommodation options a few miles from the airport.

What can I see and do near the airport in Florence?

Sights like Mcleod Regional Medical Center and Florence Stockade highlight some of the local culture. You can enjoy live performances at Florence Little Theatre and FMU Performing Arts Center. If you've got some time to explore the area around Florence, SC (FLO-Florence Regional), you may want to make a stop by Dr. Eddie Floyd Tennis Center, Southgate Bowling Center and CarolinaBank Field.