
Florence Holidays
Book a Hotel + Flight or Car together to unlock savings
Top hotels in Florence

Howard Johnson by Wyndham Florence
2038 W Lucas Street, I-95 Exit 164, Florence, SC
Fully refundableReserve now, pay when you stay
The price is 1.800.555 ₫ per night from 30 Jun to 1 Jul
1.800.555 ₫
2.016.622 ₫ total
30 Jun - 1 Jul
includes taxes & fees
8.6/10 Excellent! (2,258 reviews)
"Room was very clean and staff very friendly. Only issues were: no stopper in the sink. Deadbolt wouldn’t latched but sources safely locked. Would stay again."
Reviewed on 29 Jun 2025

Comfort Inn & Suites
527 Woody Jones Blvd, Florence, SC
Fully refundableReserve now, pay when you stay
The price is 2.875.669 ₫ per night from 27 Jul to 28 Jul
2.875.669 ₫
3.220.749 ₫ total
27 Jul - 28 Jul
includes taxes & fees
9/10 Wonderful! (1,004 reviews)
"I often stay in Florence when traveling for work. I have stayed in several different hotels, but this one is my favorite. Great value! As a female, I felt safe traveling and staying here."
Reviewed on 27 Jun 2025

Park Inn by Radisson Florence, SC
1729 Mandeville Road, Florence, SC
Fully refundableReserve now, pay when you stay
The price is 2.583.405 ₫ per night from 6 Jul to 7 Jul
2.583.405 ₫
2.893.414 ₫ total
6 Jul - 7 Jul
includes taxes & fees
9/10 Wonderful! (2,070 reviews)
"Very comfortable stay, well maintained and clean property. Room was well stocked. Breakfast buffet had everything needed for a quick stop before getting back on the road. I would definitely stay here again."
Reviewed on 23 Jun 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Popular places to visit

Magnolia Mall
You can do some window-shopping at Magnolia Mall during your trip to Florence. While in this family-friendly area, you can savour the top-notch restaurants.
Mcleod Regional Medical Center
If Mcleod Regional Medical Center is what brings you to town, hopefully you'll have a chance to explore more of Florence.
Florence National Cemetery
Enjoy a stop at Florence National Cemetery, a landmark worth seeing in Florence. While in this trendy area, you can savour the top-notch restaurants.