East Main Street Travel Guide

Grand Junction

A tall, narrow rock formation in a desert canyon with layered rock walls and sparse vegetation.

Top hotels in East Main Street

Grand Vista Hotel

Grand Vista Hotel

3.5 out of 5
2790 Crossroads Blvd Grand Junction CO
The price is 2.438.826 ₫ per night from 30 Aug to 31 Aug
2.438.826 ₫
2.796.357 ₫ total
30 Aug - 31 Aug
includes taxes & fees
Stay at this business-friendly hotel in Grand Junction. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the restaurant and the helpful staff ...
Grand Vista Hotel
Super 8 by Wyndham Grand Junction Colorado

Super 8 by Wyndham Grand Junction Colorado

2 out of 5
728 Horizon Drive Grand Junction CO
The price is 1.872.418 ₫ per night from 2 Aug to 3 Aug
1.872.418 ₫
2.146.914 ₫ total
2 Aug - 3 Aug
includes taxes & fees
Stay at this hotel in Grand Junction. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms in their reviews. ...
Super 8 by Wyndham Grand Junction Colorado
Ramada by Wyndham Grand Junction

Ramada by Wyndham Grand Junction

2.5 out of 5
752 Horizon Dr Grand Junction CO
Fully refundableReserve now, pay when you stay
The price is 1.942.637 ₫ per night from 17 Aug to 18 Aug
1.942.637 ₫
2.227.428 ₫ total
17 Aug - 18 Aug
includes taxes & fees
Stay at this business-friendly hotel in Grand Junction. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the pool in their ...
Ramada by Wyndham Grand Junction
La Quinta Inn & Suites by Wyndham Grand Junction

La Quinta Inn & Suites by Wyndham Grand Junction

3 out of 5
2761 Crossroads Blvd Grand Junction CO
The price is 2.937.647 ₫ per night from 2 Aug to 3 Aug
2.937.647 ₫
3.368.291 ₫ total
2 Aug - 3 Aug
includes taxes & fees
Stay at this business-friendly hotel in Grand Junction. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
La Quinta Inn & Suites by Wyndham Grand Junction
Quality Inn Grand Junction near University

Quality Inn Grand Junction near University

3 out of 5
733 Horizon Dr Grand Junction CO
The price is 2.269.287 ₫ per night from 23 Aug to 24 Aug
2.269.287 ₫
2.601.898 ₫ total
23 Aug - 24 Aug
includes taxes & fees
Stay at this golf hotel in Grand Junction. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their ...
Quality Inn Grand Junction near University
Wine Country Inn Palisade

Wine Country Inn Palisade

3.5 out of 5
777 Grande River Drive Palisade CO
The price is 4.953.613 ₫ per night from 3 Aug to 4 Aug
4.953.613 ₫
5.471.751 ₫ total
3 Aug - 4 Aug
includes taxes & fees
Stay at this business-friendly hotel in Palisade. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the pool in their reviews. ...
9.6/10 Exceptional! (1,013 reviews)
"clean and quiet"

Reviewed on 28 Jul 2026

Wine Country Inn Palisade
See all 553 properties in East Main Street
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in East Main Street

Find the best East Main Street areas for the activities you enjoy most.
An aerial view of a city at night with illuminated streets and buildings.

Downtown

Though Downtown may not have many top sights, you can venture to the surrounding area to see attractions like Western Colorado Botanical Gardens and Bananas Fun Park.

A winding road with a yellow warning sign, surrounded by rocky cliffs and sparse vegetation.

Redlands

You'll enjoy the mountain views and wineries in Redlands. You might want to make time for a stop at Colorado National Monument or Redlands Mesa Golf Club.

A lone tree in a rocky landscape with mountains in the background.

Pear Park

While visiting Pear Park, you might make a stop by sights like Colorado River and James M. Robb – Colorado River State Park.

A canyon landscape with prominent rock formations, a distant city, and snow-capped mountains in the background.

Horizon Drive District

Horizon Drive District might not have many top sights, but Canyon View Park and Bananas Fun Park are two attractions nearby that you can check out.

A canyon landscape with prominent red rock formations and a distant mountain range.

Historic Grand Junction

Visitors highly recommend Historic Grand Junction for its abundant dining options, and you can make a stop by Museum of the West while you're in town.

East Main Street Travel Guide

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