Search Hotels in South Central Houston, Houston

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
29 Aug - 30 Aug
Tomorrow
30 Aug - 31 Aug
This weekend
29 Aug - 31 Aug
Next weekend
5 Sep - 7 Sep

Filter by

Guest rating
Guest rating
Property class

Top Trending Hotels Near South Central Houston, Houston

Our top choices for South Central Houston hotels

Hotel Zaza Houston Museum District
1 bedroom, premium bedding, pillow-top beds, minibar

Hotel Zaza Houston Museum District

4.5 star property
9.0 out of 10, Wonderful, (1759)
"Had a quick stay here and would come back again!"
Hotel Zaza Houston Museum District
Bluestar Inn
1 bedroom, individually furnished, desk, iron/ironing board

Bluestar Inn

2.5 star property
9.0 out of 10, Wonderful, (258)
"Clean and neat"
The price is 1.819.254 ₫
2.128.527 ₫ total
includes taxes & fees
31 Aug - 1 Sept
Bluestar Inn
Hotel ZaZa Houston Memorial City
Sauna

Hotel ZaZa Houston Memorial City

4.0 star property
9.4 out of 10, Exceptional, (1006)
"Great celebration location for our 19th Anniversary "
Hotel ZaZa Houston Memorial City
Wanderstay Boutique Hotel
Double Room, 1 Queen Bed with Sofa bed | 1 bedroom, in-room safe, individually decorated, individually furnished

Wanderstay Boutique Hotel

2.0 star property
10.0 out of 10, Exceptional, (41)
"Great stay!"
The price is 3.388.559 ₫
3.964.613 ₫ total
includes taxes & fees
1 Sept - 2 Sept
Wanderstay Boutique Hotel
Paradise Palace Best Rooftop in HTX w Hot Tub
House | 4 bedrooms, desk, iron/ironing board, Internet

Paradise Palace Best Rooftop in HTX w Hot Tub

3.0 star property
The price is 8.162.192 ₫
17.045.882 ₫ total
includes taxes & fees
1 Sept - 2 Sept
Paradise Palace Best Rooftop in HTX w Hot Tub
Signature Inn Houston Galleria
Lobby

Signature Inn Houston Galleria

2.5 star property
8.4 out of 10, Very good, (533)
"The room was stinky and comfortable looked thin, itchy and unsanitary. The hotel give motels vibes."
The price is 1.819.254 ₫
2.128.527 ₫ total
includes taxes & fees
31 Aug - 1 Sept
Signature Inn Houston Galleria
Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home
House, 3 Bedrooms | Private kitchen | Fridge, oven, coffee/tea maker, electric kettle

Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home

3.0 star property
The price is 5.570.608 ₫
15.463.659 ₫ total
includes taxes & fees
31 Aug - 1 Sept
Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home
Newly Built Modern 3 Bedroom Houston Home
House | 3 bedrooms, Internet

Newly Built Modern 3 Bedroom Houston Home

2.0 star property
10.0 out of 10, Exceptional, (2)
"The pictures do not do this property justice. The three story home has 3 beautiful bedrooms, each with luxurious bathrooms. The main bedroom and the living room has a small patio and then there's a rooftop seating area that is an excellent spot for gazing at the Houston night skyline. The quiet area is gated off a not too busy street in a beautiful neighborhood. We did have a couple of issues upon our arrival but the hosts were on top of it and had it resolved the next day. They have great...
Newly Built Modern 3 Bedroom Houston Home
The Westin Houston Medical Center/Museum District
Outdoor pool, free pool cabanas, pool umbrellas

The Westin Houston Medical Center/Museum District

4.0 star property
9.0 out of 10, Wonderful, (1006)
"Always great stay"
The price is 3.609.059 ₫
4.492.196 ₫ total
includes taxes & fees
7 Sept - 8 Sept
The Westin Houston Medical Center/Museum District
Americas Best Value Inn Medical Center Downtown
Desk, free WiFi, bed sheets, alarm clocks

Americas Best Value Inn Medical Center Downtown

2.0 star property
7.8 out of 10, Good, (1003)
"Cheap, quiet, clean, and friendly staff"
The price is 1.860.121 ₫
2.176.341 ₫ total
includes taxes & fees
4 Sept - 5 Sept
Americas Best Value Inn Medical Center Downtown
The Oasis Checkmate HTX Rooftop
House | 4 bedrooms, desk, soundproofing, iron/ironing board

The Oasis Checkmate HTX Rooftop

3.0 star property
10.0 out of 10, Exceptional, (2)
"This place is amazing! Beautiful decor and location is perfect for any event near the convention center. Safe and secure. Hosts were responsive and friendly. I let them know the ironing board was missing and they had a new one sent from Amazon the next day! 10/10 recommend and will rebook. "
The Oasis Checkmate HTX Rooftop
Houston Marriott Medical Center/Museum District
Lobby

Houston Marriott Medical Center/Museum District

4.0 star property
9.0 out of 10, Wonderful, (1001)
"Close to the hospital "
The price is 4.234.091 ₫
5.763.279 ₫ total
includes taxes & fees
12 Sept - 13 Sept
Houston Marriott Medical Center/Museum District
The Green Haus Luxxe Cabana Rooftop Retreat
Apartment | 4 bedrooms, desk, Internet

The Green Haus Luxxe Cabana Rooftop Retreat

2.0 star property
10.0 out of 10, Exceptional, (1)
The price is 7.746.646 ₫
18.058.920 ₫ total
includes taxes & fees
1 Sept - 2 Sept
The Green Haus Luxxe Cabana Rooftop Retreat
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
Outdoor pool

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

3.5 star property
9.6 out of 10, Exceptional, (190)
"This was a wonderful place to stay!!"
The price is 5.455.692 ₫
6.778.500 ₫ total
includes taxes & fees
10 Sept - 11 Sept
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
La Maison in Midtown an urban B&B
Exterior

La Maison in Midtown an urban B&B

3.5 star property
9.8 out of 10, Exceptional, (519)
"Nice property we are enjoying our stay. "
The price is 4.717.724 ₫
5.519.737 ₫ total
includes taxes & fees
10 Sept - 11 Sept
La Maison in Midtown an urban B&B
Modern Cozy Home with King Bed
Comfort Townhome | Private kitchen | Full-sized fridge, microwave, oven, dishwasher

Modern Cozy Home with King Bed

3.5 star property
9.4 out of 10, Exceptional, (20)
"Very spacious and close to just about everything. The view is amazing too"
The price is 3.558.060 ₫
9.170.571 ₫ total
includes taxes & fees
9 Sept - 10 Sept
Modern Cozy Home with King Bed
InterContinental Houston by IHG
Reception

InterContinental Houston by IHG

4.0 star property
9.2 out of 10, Wonderful, (1007)
"Great clean property, pleasant atmosphere. "
The price is 3.768.908 ₫
4.936.742 ₫ total
includes taxes & fees
7 Sept - 8 Sept
InterContinental Houston by IHG
Hilton University of Houston
1 bedroom, premium bedding, down duvets, pillow-top beds

Hilton University of Houston

3.5 star property
8.8 out of 10, Excellent, (857)
"Perfect for new students and families."
The price is 4.234.091 ₫
4.953.888 ₫ total
includes taxes & fees
10 Sept - 11 Sept
Hilton University of Houston
Southmore Boulevard Motel
Standard Room, 1 King Bed | 1 bedroom, premium bedding, blackout curtains, free WiFi

Southmore Boulevard Motel

2.0 star property
5.4 out of 10, (219)
"A classical Motel like in a Movie. The staff was really kind and helpful."
The price is 1.581.360 ₫
1.850.191 ₫ total
includes taxes & fees
10 Sept - 11 Sept
Southmore Boulevard Motel
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Daily buffet breakfast for a fee

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4.0 star property
8.4 out of 10, Very good, (417)
"Great stay, shuttle to MD Anderson very convenient, they let us check out 1 hour later to accommodate Dr appt. "
The price is 3.248.291 ₫
3.800.500 ₫ total
includes taxes & fees
4 Sept - 5 Sept
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Where to stay in South Central Houston

Find the best South Central Houston areas for the activities you enjoy most.
Discovery Green showing city views, modern architecture and a high-rise building

Downtown Houston

Gourmet restaurants acclaimed theatres and top sights from Toyota Center to Daikin Park – discover Downtown Houston, a destination also famous for its sports teams.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Gerald D. Hines Waterwall Park.

Texas Medical Center

2 out of top 10 points of interest in this area

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Theater District

Restaurants and seafood restaurants are just a few things travellers like about Theater District. A stop by Wortham Center is also recommended if you've got time to explore the area.

Houston which includes a skyscraper and a city

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Main Street Square Station.

Top South Central Houston Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's it like in South Central Houston?

Travellers are sure to enjoy a stay in Houston's South Central Houston neighbourhood. Looking for sights you might find in a travel guide about South Central Houston? Consider a visit to Houston Zoo while you're in the neighbourhood.

How many hotels can I expect to find in the South Central Houston area?

Expedia has 1124 hotels and other accommodation options in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.

If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?

Yes! Most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals available in South Central Houston.

What is there to do around this Houston neighbourhood?

Spend some time exploring the great outdoors at Hermann Park, James Turrell's Twilight Epiphany Skyscape and Cullen Sculpture Garden. Houston Zoo and Continental Club are some other stops worth a visit in the neighbourhood. Toyota Center and Daikin Park are some popular places to visit in the area around South Central Houston. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.

How can I get around South Central Houston and the greater Houston area?

For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station or Ensemble/HCC Station.