
South Central Houston Holidays
Book a Hotel + Flight or Car together to unlock savings
Where to stay in South Central Houston
Find the best South Central Houston areas and neighborhoods for the activities you enjoy most. Learn more about South Central Houston

Downtown Houston
3 out of top 10 points of interest in this area
4/5(25 area reviews)
Gourmet restaurants acclaimed theatres and top sights from Toyota Center to Daikin Park – discover Downtown Houston, a destination also famous for its sports teams.
Top hotels in South Central Houston

Hotel Zaza Houston Museum District
5701 Main Street, Houston, TX
Fully refundableReserve now, pay when you stay
8.8/10 Excellent! (1,786 reviews)
"Hotel was a beautiful experience from the property to the staff. I felt like a Queen during my stay!"
Reviewed on 2 Oct 2025

Hilton Houston Plaza/Medical Center
6633 Travis St, Houston, TX
The price is 2.181.215 ₫ per night from 9 Nov to 10 Nov
2.181.215 ₫
2.582.576 ₫ total
9 Nov - 10 Nov
includes taxes & fees
8.2/10 Very Good! (1,624 reviews)
"Front desk staff were awesome"
Reviewed on 7 Oct 2025

InterContinental Houston by IHG
6750 Main St, Houston, TX
Fully refundable
The price is 3.733.695 ₫ per night from 19 Oct to 20 Oct
3.733.695 ₫
4.895.552 ₫ total
19 Oct - 20 Oct
includes taxes & fees
9.2/10 Wonderful! (1,008 reviews)
"Very close to hospital"
Reviewed on 8 Oct 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Popular places to visit

Rice University
Walk around the campus of Rice University, a top university in Houston. Experience the area's acclaimed theatre scene and fascinating museums.

University of Houston
Walk around the campus of University of Houston, a top university in Houston. Experience the great live music and lively festivals in this vibrant area.

Houston Zoo
Why not visit the native and exotic animals at Houston Zoo and see why this is a favourite attraction in Houston? Experience the area's fascinating museums and lively festivals.