South Central Houston Holidays

Book a Hotel + Flight or Car together to unlock savings

Where to stay in South Central Houston

Find the best South Central Houston areas and neighborhoods for the activities you enjoy most. Learn more about South Central Houston
Discovery Green showing city views, modern architecture and a high-rise building

Downtown Houston

3 out of top 10 points of interest in this area
4/5(25 area reviews)

Gourmet restaurants acclaimed theatres and top sights from Toyota Center to Daikin Park – discover Downtown Houston, a destination also famous for its sports teams.

Find hotels in Downtown Houston

Top hotels in South Central Houston

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St, Houston, TX
Fully refundableReserve now, pay when you stay
The price is 2.229.464 ₫ per night from 4 Sept to 5 Sept
2.229.464 ₫
2.639.042 ₫ total
4 Sept - 5 Sept
includes taxes & fees
8.2/10 Very Good! (1,540 reviews)
Weekend getaway
"Me and my sister stayed here for a three day trip. We absolutely had a great time great. Every one that worked here that we came in contact with were so nice and helpful. Our room was so clean and nice. It’s one of the best hotels I’ve been to in a while. We will definitely be coming back. And another ..."

Reviewed on 26 Aug 2025

Hilton Houston Plaza/Medical Center
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street, Houston, TX
Fully refundableReserve now, pay when you stay
8.8/10 Excellent! (1,755 reviews)
"Great rooms Very large Great pool Super support team Fast check in Smooth out processing by front desk staff"

Reviewed on 24 Aug 2025

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Hotel Zaza Houston Museum District
InterContinental Houston by IHG

InterContinental Houston by IHG

4 out of 5
6750 Main St, Houston, TX
Fully refundable
The price is 3.761.901 ₫ per night from 1 Sept to 2 Sept
3.761.901 ₫
4.928.744 ₫ total
1 Sept - 2 Sept
includes taxes & fees
9.2/10 Wonderful! (1,004 reviews)
"Love this hotel! It’s clean, comfortable and convenient to any of the MDAnderson medical buildings. Restaurant and bar are also great. Many dining options within walking distance."

Reviewed on 18 Aug 2025

InterContinental Houston by IHG
See all 1,128 properties in South Central Houston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a South Central Houston holiday package cost?
Starting from a low , a holiday package is your passport to inexpensive travel. Custom build your South Central Houston getaway by selecting from our huge range of hotels, flights and rental cars.
How do I get a cheap travel package to South Central Houston?
Combining your flight and hotel with Expedia won't just save you time — it'll save you a tidy sum too. A South Central Houston holiday package makes it easy to put together the perfect trip. With more than 550 airlines across the world to choose from, finding flights that suit your busy schedule won't be a problem. On top of that, we have over 1null000null000 hotels globally to select from. Now that's what we call choice. Whatever your budget, Expedia will help show you the world.
How far in advance should I book my South Central Houston holiday?
While not all air carriers release ticket prices early, you can usually compare international fares on Expedia up to 12 months in advance. This is the time you can nab some incredible deals. If you've left everything to the last minute, you might get lucky. Low prices sometimes appear just weeks before departure.
What does an Expedia South Central Houston travel package include?
That depends on what you're after. If you're travelling by yourself, you might decide to bundle hotels and flights. Taking the whole family to South Central Houston? A travel package including hotels, flights and rental cars might suit you better. Expedia gives you the flexibility to build your own travel package.
What should I know before booking a South Central Houston travel package?
Design deals that suit your budget with an Expedia package. Flights, hotels, rental cars — we have everything you need to plan your escape. You'll save a packet just by combining your bookings. Whether you're embarking on a ski trip or drinking cocktails on a beach, your dream holiday is just a few clicks away.
Can I choose my airline with a South Central Houston Expedia holiday package?
Yes, you sure can. We offer more than 550 airline partners worldwide, so select the carrier that matches your budget needs.
If I'm not able to travel, can I cancel my South Central Houston holiday package?
Yes, it's possible to cancel your South Central Houston booking if your travel plans have been upended. Whether you'll incur a penalty or not depends on your airline, hotel or car rental company. It may be possible to cancel or change your booking free of charge if you booked in the last 24 hours. Head to our Customer Service Portal to find out more.

Popular places to visit

Rice University

Rice University

Walk around the campus of Rice University, a top university in Houston. Experience the area's acclaimed art galleries and lively festivals.

Rice University
University of Houston

University of Houston

Walk around the campus of University of Houston, a top university in Houston. Experience the great live music and acclaimed art galleries in this vibrant area.

University of Houston
Houston Zoo

Houston Zoo

Why not visit the native and exotic animals at Houston Zoo and see why this is a favourite attraction in Houston? Experience the area's acclaimed art galleries and fascinating museums.

Houston Zoo