South Central Houston Travel Guide

Houston

TMC
TMC
Taken from the back parking garage.
Taken along bike trail.
Random structure in the museum district.

Popular places to visit


Top hotels in South Central Houston

Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
The price is 10.274.071 ₫ per night from 2 Feb to 3 Feb
10.274.071 ₫
13.333.764 ₫ total
2 Feb - 3 Feb
includes taxes & fees
Stay at this luxury aparthotel in Houston. Enjoy free Wi-Fi, a full-service spa and a rooftop terrace. Our guests praise the helpful staff in their reviews. ...
8.8/10 Excellent! (1,887 reviews)
Room -good, staff -very personable and professional

Reviewed on 25 Jan 2026

Hotel Zaza Houston Museum District
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
The price is 2.385.932 ₫ per night from 1 Feb to 2 Feb
2.385.932 ₫
2.821.929 ₫ total
1 Feb - 2 Feb
includes taxes & fees
Stay at this luxury hotel in Houston. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in their reviews. ...
8.2/10 Very Good! (1,823 reviews)
Staff is extremely hospitable.

Reviewed on 19 Jan 2026

Hilton Houston Plaza/Medical Center
Downtowner Inns - Houston Downtown

Downtowner Inns - Houston Downtown

2 out of 5
2510 Hamilton St Houston TX
The price is 2.239.758 ₫ per night from 29 Jan to 30 Jan
2.239.758 ₫
2.620.648 ₫ total
29 Jan - 30 Jan
includes taxes & fees
Stay at this hotel in Houston. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Toyota Center and NRG Stadium are located nearby.
7.8/10 Good! (49 reviews)
Staff was helpful

Reviewed on 20 Jan 2026

Downtowner Inns - Houston Downtown
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4 out of 5
1709 DRYDEN ROAD Houston TX
The price is 3.787.549 ₫ per night from 1 Feb to 2 Feb
3.787.549 ₫
4.714.362 ₫ total
1 Feb - 2 Feb
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service and a 24-hour health club. Our guests praise the helpful staff and ...
9/10 Wonderful! (1,074 reviews)
Clean room, service/employees were spectacular.

Reviewed on 26 Jan 2026

The Westin Houston Medical Center/Museum District
InterContinental Houston by IHG

InterContinental Houston by IHG

4 out of 5
6750 Main St Houston TX
The price is 4.217.556 ₫ per night from 1 Feb to 2 Feb
4.217.556 ₫
5.458.461 ₫ total
1 Feb - 2 Feb
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff and ...
9.2/10 Wonderful! (1,003 reviews)
Great staff, beautiful lobby, comfortable and clean room

Reviewed on 23 Jan 2026

InterContinental Houston by IHG
DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4 out of 5
6800 Main Street Houston TX
The price is 2.344.018 ₫ per night from 1 Feb to 2 Feb
2.344.018 ₫
2.742.501 ₫ total
1 Feb - 2 Feb
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff in ...
8.2/10 Very Good! (504 reviews)
Staff was great, room was clean and perfect location for our needs. Were there for medical appointment and if we ever need to go back will definitely stay again.

Reviewed on 22 Jan 2026

DoubleTree by Hilton Houston Medical Center Hotel & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around South Central Houston

Phoenix midtown skyline with a Saguaro Cactus and other desert scenery in the foreground.

Midtown

Midtown is well liked for its restaurants and live music. If you're hoping to get in some sightseeing, Houston Fire Museum and Midtown Arts and Theater Center Houston are top spots, and you can jump on the metro at McGowen Station or Ensemble/HCC Station to get around.

Midtown
Houston_EastDowntownHouston_6004016_9

East Downtown Houston

1/5(1 area review)

The restaurants and live music are just a few things visitors like about East Downtown Houston. Shell Energy Stadium and Giant Beatles Statues are worthwhile spots to check out, and you can hop on the metro at Leeland/Third Ward Station or EaDo/Stadium Station to get around the larger area.

East Downtown Houston
TMC

Museum District

Known for its abundant dining options and interesting museums, there's plenty to explore in Museum District. Top attractions like Children's Museum of Houston and Houston Natural Science Museum are major draws, and you can catch the metro at Museum District Station or Hermann Park/Rice U Station to see more of the city.

Museum District
Taken from the parking garage.

#UrbanJungle

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.

Houston Central Business District
Discovery Green showing city views, modern architecture and a high-rise building

Houston Convention District

If you're looking for things to see and do in Houston Convention District, ample dining options and great live music are highlights. You might also check out Kinder Lake while you're visiting, and jump aboard the metro at Convention District Station to get around town.

Houston Convention District
Discovery Green showing city views, modern architecture and a high-rise building

Downtown Houston

4/5(25 area reviews)

Gourmet restaurants acclaimed theatres and top sights from Daikin Park to Jesse H. Jones Hall – discover Downtown Houston, a destination also famous for its sports teams.

Downtown Houston


South Central Houston Travel Guide

Choose two or more items and save on your trip: