Photo by George Zimzores
Search Hotels in South Central Houston, Houston
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for South Central Houston hotels
DoubleTree by Hilton Houston Medical Center Hotel & Suites
DoubleTree by Hilton Houston Medical Center Hotel & SuitesSouth Central Houston
8.4 out of 10, Very good, (505 reviews)
"Staff was great, room was clean and perfect location for our needs. Were there for medical appointment and if we ever need to go back will definitely stay again."
Kim
The price is 2.263.459 ₫
2.648.248 ₫ total
includes taxes & fees
1 Feb - 2 Feb
Hotel Zaza Houston Museum District
Hotel Zaza Houston Museum DistrictSouth Central Houston
9.0 out of 10, Wonderful, (1,890 reviews)
"An amzing stay, great staff and overal luxery feeling"
Wendy
Hilton Houston Plaza/Medical Center
Hilton Houston Plaza/Medical CenterSouth Central Houston
8.4 out of 10, Very good, (1,833 reviews)
"Amazing room, great rate! "
Sherri
The price is 2.267.395 ₫
2.683.294 ₫ total
includes taxes & fees
22 Feb - 23 Feb
Rodeway Inn & Suites Houston near Medical Center
Rodeway Inn & Suites Houston near Medical CenterSouth Central Houston
6.0 out of 10, (498 reviews)
"Very economical. Great price for one night stay."
AUGUSTIN
The price is 1.534.953 ₫
1.795.895 ₫ total
includes taxes & fees
27 Jan - 28 Jan
Wanderstay Boutique Hotel
Wanderstay Boutique HotelSouth Central Houston
9.8 out of 10, Exceptional, (61 reviews)
"Perfect space for my overnight stay but I had dreams of renting the full space for a family event in the future. "
Marva
The price is 3.117.668 ₫
3.648.039 ₫ total
includes taxes & fees
1 Feb - 2 Feb
La Maison in Midtown an urban B&B
La Maison in Midtown an urban B&BSouth Central Houston
9.8 out of 10, Exceptional, (547 reviews)
"Good rooms and location, great staff!"
Eugene
The price is 4.697.497 ₫
5.496.071 ₫ total
includes taxes & fees
28 Jan - 29 Jan
Houston Marriott Medical Center/Museum District
Houston Marriott Medical Center/Museum DistrictSouth Central Houston
9.0 out of 10, Wonderful, (1,002 reviews)
"Very courteous staff"
Jolynn
The price is 4.439.003 ₫
6.042.173 ₫ total
includes taxes & fees
31 Jan - 1 Feb
InterContinental Houston by IHG
InterContinental Houston by IHGSouth Central Houston
9.2 out of 10, Wonderful, (1,006 reviews)
"Staff courteous
Pretty clean
Nice upgrade in the lobby area "
Sandra
The price is 4.225.123 ₫
5.468.254 ₫ total
includes taxes & fees
1 Feb - 2 Feb
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults OnlySouth Central Houston
9.6 out of 10, Exceptional, (202 reviews)
"I absolutely loved my stay here!!"
Daniella
The price is 5.432.301 ₫
6.749.437 ₫ total
includes taxes & fees
28 Jan - 29 Jan
The Westin Houston Medical Center/Museum District
The Westin Houston Medical Center/Museum DistrictSouth Central Houston
9.2 out of 10, Wonderful, (1,076 reviews)
"Great place to stay "
Ernest
The price is 3.794.344 ₫
4.722.819 ₫ total
includes taxes & fees
1 Feb - 2 Feb
The Oasis Checkmate HTX Rooftop
The Oasis Checkmate HTX RooftopSouth Central Houston
10.0 out of 10, Exceptional, (2 reviews)
"This place is amazing! Beautiful decor and location is perfect for any event near the convention center. Safe and secure. Hosts were responsive and friendly. I let them know the ironing board was missing and they had a new one sent from Amazon the next day! 10/10 recommend and will rebook. "
Veronica
The price is 7.289.094 ₫
17.979.027 ₫ total
includes taxes & fees
29 Jan - 30 Jan
Americas Best Value Inn Medical Center Downtown
Americas Best Value Inn Medical Center DowntownSouth Central Houston
8.0 out of 10, Very good, (1,004 reviews)
"Nice hotel"
Robert Jeanmard
The price is 1.851.444 ₫
2.166.098 ₫ total
includes taxes & fees
27 Jan - 28 Jan
Hilton University of Houston
Hilton University of HoustonSouth Central Houston
9.0 out of 10, Wonderful, (891 reviews)
"Nice place to stay"
Alexandra
The price is 3.851.948 ₫
4.506.779 ₫ total
includes taxes & fees
15 Feb - 16 Feb
Southmore Boulevard Motel
Southmore Boulevard MotelSouth Central Houston
5.6 out of 10, (229 reviews)
"A classical Motel like in a Movie. The staff was really kind and helpful."
Lisa-Maria
The price is 1.771.402 ₫
2.072.541 ₫ total
includes taxes & fees
27 Jan - 28 Jan
Downtowner Inns - Houston Downtown
Downtowner Inns - Houston DowntownSouth Central Houston
7.8 out of 10, Good, (50 reviews)
"Staff was helpful"
Jonathan
The price is 2.243.776 ₫
2.625.219 ₫ total
includes taxes & fees
29 Jan - 30 Jan
Wanderstay Houston Hostel
Wanderstay Houston HostelSouth Central Houston
8.2 out of 10, Very good, (190 reviews)
"This is an amazing place to stay."
Darius
The price is 1.447.564 ₫
1.693.461 ₫ total
includes taxes & fees
27 Jan - 28 Jan
Extended Stay America Suites Houston Med Ctr Braeswood Bl
Extended Stay America Suites Houston Med Ctr Braeswood BlSouth Central Houston
5.8 out of 10, (1,017 reviews)
"Clean"
William
The price is 1.653.047 ₫
1.941.458 ₫ total
includes taxes & fees
30 Jan - 31 Jan
Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home
Sophisticated Urban Retreat With Skyline Views 3 Bedroom HomeSouth Central Houston
The price is 6.233.762 ₫
18.020.056 ₫ total
includes taxes & fees
27 Jan - 28 Jan
Newly Built Modern 3 Bedroom Houston Home
Newly Built Modern 3 Bedroom Houston HomeSouth Central Houston
10.0 out of 10, Exceptional, (2 reviews)
"The pictures do not do this property justice. The three story home has 3 beautiful bedrooms, each with luxurious bathrooms. The main bedroom and the living room has a small patio and then there's a rooftop seating area that is an excellent spot for gazing at the Houston night skyline. The quiet area is gated off a not too busy street in a beautiful neighborhood.
We did have a couple of issues upon our arrival but the hosts were on top of it and had it resolved the next day. They have great...
robin
The price is 2.862.674 ₫
9.649.853 ₫ total
includes taxes & fees
1 Feb - 2 Feb
The Green Haus Luxxe Cabana Rooftop Retreat
The Green Haus Luxxe Cabana Rooftop RetreatSouth Central Houston
10.0 out of 10, Exceptional, (1 review)
The price is 6.864.888 ₫
17.482.705 ₫ total
includes taxes & fees
27 Jan - 28 Jan
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in South Central Houston
Find the best South Central Houston areas for the activities you enjoy most.
Downtown Houston
Gourmet restaurants acclaimed theatres and top sights from Daikin Park to Jesse H. Jones Hall – discover Downtown Houston, a destination also famous for its sports teams.
The Galleria
Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.
Texas Medical Center
Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.
Montrose
Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.
Top South Central Houston Hotel Reviews
Wanderstay Boutique Hotel
10/10 Excellent
