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Our top choices for Illinois Medical District hotels

Hampton Inn & Suites Chicago Medical District UIC

Hampton Inn & Suites Chicago Medical District UIC
2.5 star property
Illinois Medical District
9.6 out of 10, Exceptional, (597 reviews)
"Clean hotel, no complaints at all!"
United States
Kira
The price is 3.687.172 ₫
4.383.936 ₫ total
includes taxes & fees
25 May - 26 May
Hampton Inn & Suites Chicago Medical District UIC

Hyatt Place Chicago Medical/University District

Hyatt Place Chicago Medical/University District
3.0 star property
Illinois Medical District
9.0 out of 10, Wonderful, (1,496 reviews)
"Excellent place to stay! Breakfast was great and super friendly staff!"
United States
Michelle
The price is 4.479.840 ₫
5.326.082 ₫ total
includes taxes & fees
25 May - 26 May
Hyatt Place Chicago Medical/University District

Hyatt House Chicago Medical/University District

Hyatt House Chicago Medical/University District
3.5 star property
Illinois Medical District
9.0 out of 10, Wonderful, (1,532 reviews)
"Very good stay and locatipn."
United States
Patricia
The price is 4.717.008 ₫
5.608.052 ₫ total
includes taxes & fees
25 May - 26 May
Hyatt House Chicago Medical/University District

Hyatt Place Itasca

Hyatt Place Itasca
3.0 star property
30.3 km from Illinois Medical District
8.8 out of 10, Excellent, (1,097 reviews)
"Staff was very helpful and room was exactly what was advertised"
United States
Allen
The price is 2.889.705 ₫
3.206.994 ₫ total
includes taxes & fees
26 May - 27 May
Hyatt Place Itasca

SureStay Plus Hotel by Best Western Chicago Lombard

SureStay Plus Hotel by Best Western Chicago Lombard
2.5 star property
27.8 km from Illinois Medical District
9.0 out of 10, Wonderful, (2,748 reviews)
"Great stay. The room was clean and the breakfast was good."
United States
Nargis
The price is 2.239.656 ₫
2.485.569 ₫ total
includes taxes & fees
20 May - 21 May
SureStay Plus Hotel by Best Western Chicago Lombard

Sable at Navy Pier Chicago, Curio Collection by Hilton

Sable at Navy Pier Chicago, Curio Collection by Hilton
4.0 star property
Streeterville, 6.4 km from Illinois Medical District
9.4 out of 10, Exceptional, (2,505 reviews)
"Great view and room was very clean!"
United States
beth
The price is 4.681.433 ₫
6.474.373 ₫ total
includes taxes & fees
26 May - 27 May
Sable at Navy Pier Chicago, Curio Collection by Hilton

The Chicago Hotel Collection Ambassador Gold Coast

The Chicago Hotel Collection Ambassador Gold Coast
4.0 star property
Gold Coast, 5.6 km from Illinois Medical District
8.2 out of 10, Very good, (1,457 reviews)
"A nice stay and lovely location. "
United States
Robin
The price is 3.792.053 ₫
4.508.564 ₫ total
includes taxes & fees
25 May - 26 May
The Chicago Hotel Collection Ambassador Gold Coast

Swissotel - Chicago

Swissotel - Chicago
4.5 star property
5 km from Illinois Medical District
9.0 out of 10, Wonderful, (3,330 reviews)
"Wonderful location right on the river. Fitness area wonderful, staff helpful. Would stay again!"
United States
Saleem
The price is 5.422.846 ₫
7.375.337 ₫ total
includes taxes & fees
24 May - 25 May
Swissotel - Chicago

Sofitel Chicago Magnificent Mile

Sofitel Chicago Magnificent Mile
4.5 star property
5.1 km from Illinois Medical District
9.4 out of 10, Exceptional, (2,474 reviews)
"Great hotel, clean and modern"
United States
Wyatt
The price is 5.668.315 ₫
7.522.505 ₫ total
includes taxes & fees
25 May - 26 May
Sofitel Chicago Magnificent Mile

Sheraton Grand Chicago Riverwalk

Sheraton Grand Chicago Riverwalk
4.0 star property
Streeterville, 5.1 km from Illinois Medical District
8.6 out of 10, Excellent, (1,630 reviews)
"It was very clean, beautiful place"
United States
Grisel
The price is 5.668.315 ₫
7.679.037 ₫ total
includes taxes & fees
25 May - 26 May
Sheraton Grand Chicago Riverwalk

Hilton Garden Inn Chicago Downtown South Loop

Hilton Garden Inn Chicago Downtown South Loop
3.0 star property
The Loop, 4.1 km from Illinois Medical District
8.8 out of 10, Excellent, (2,005 reviews)
"Great location and clean room"
United States
Hyacinthe
The price is 3.543.817 ₫
4.213.245 ₫ total
includes taxes & fees
26 May - 27 May
Hilton Garden Inn Chicago Downtown South Loop

Hilton Chicago

Hilton Chicago
4.0 star property
The Loop, 4.2 km from Illinois Medical District
8.6 out of 10, Excellent, (2,810 reviews)
"Great staff and location. "
United States
Robert
The price is 4.189.968 ₫
5.755.277 ₫ total
includes taxes & fees
25 May - 26 May
Hilton Chicago

Hotel Riu Plaza Chicago

Hotel Riu Plaza Chicago
4.0 star property
Streeterville, 5.1 km from Illinois Medical District
9.4 out of 10, Exceptional, (4,180 reviews)
"Great location & breakfast was amazing."
United States
sierra
The price is 3.926.448 ₫
5.419.552 ₫ total
includes taxes & fees
25 May - 26 May
Hotel Riu Plaza Chicago

Hyatt Place Chicago/O'Hare Airport

Hyatt Place Chicago/O'Hare Airport
3.0 star property
22.9 km from Illinois Medical District
8.4 out of 10, Very good, (3,382 reviews)
"Great place to stay"
United States
abhishek
The price is 3.399.408 ₫
3.874.535 ₫ total
includes taxes & fees
25 May - 26 May
Hyatt Place Chicago/O'Hare Airport

Embassy Suites by Hilton Chicago Downtown Magnificent Mile

Embassy Suites by Hilton Chicago Downtown Magnificent Mile
4.0 star property
Streeterville, 5.2 km from Illinois Medical District
8.2 out of 10, Very good, (2,856 reviews)
"It is a clean room and breakfast and the drinks and it was so nice in the inside the hotel"
United States
Sparkle
The price is 3.879.014 ₫
5.385.192 ₫ total
includes taxes & fees
25 May - 26 May
Embassy Suites by Hilton Chicago Downtown Magnificent Mile

La Quinta Inn & Suites by Wyndham Chicago Downtown

La Quinta Inn & Suites by Wyndham Chicago Downtown
3.0 star property
The Loop, 3.6 km from Illinois Medical District
8.6 out of 10, Excellent, (2,788 reviews)
"Very clean room, nice breakfast and really nice hotel restaurant"
United States
Hugo
The price is 3.429.713 ₫
4.541.644 ₫ total
includes taxes & fees
25 May - 26 May
La Quinta Inn & Suites by Wyndham Chicago Downtown

Silversmith Hotel Chicago Downtown

Silversmith Hotel Chicago Downtown
4.0 star property
Theatre District, 4.2 km from Illinois Medical District
9.2 out of 10, Wonderful, (2,252 reviews)
"Close to many attractions and shopping and nice unique hotel"
United States
Brittany
The price is 2.688.828 ₫
4.001.011 ₫ total
includes taxes & fees
25 May - 26 May
Silversmith Hotel Chicago Downtown

Bluegreen Vacations Hotel Blake, an Ascend Collection Hotel

Bluegreen Vacations Hotel Blake, an Ascend Collection Hotel
4.0 star property
The Loop, 3.8 km from Illinois Medical District
9.6 out of 10, Exceptional, (1,234 reviews)
"Really nice stay. "
United States
Rachael Lindsay
The price is 4.189.968 ₫
4.981.453 ₫ total
includes taxes & fees
25 May - 26 May
Bluegreen Vacations Hotel Blake, an Ascend Collection Hotel

Congress Plaza Hotel

Congress Plaza Hotel
3.5 star property
The Loop, 4.2 km from Illinois Medical District
8.0 out of 10, Very good, (10,154 reviews)
"The bar was very welcoming and the historic ambience and location was exceptional"
United States
Patricia
The price is 3.519.573 ₫
4.184.418 ₫ total
includes taxes & fees
26 May - 27 May
Congress Plaza Hotel

InterContinental Chicago Magnificent Mile by IHG

InterContinental Chicago Magnificent Mile by IHG
4.5 star property
Magnificent Mile, 4.9 km from Illinois Medical District
9.2 out of 10, Wonderful, (3,073 reviews)
"Great location ,service and staff "
United States
Tamar
The price is 5.138.640 ₫
7.032.031 ₫ total
includes taxes & fees
26 May - 27 May
InterContinental Chicago Magnificent Mile by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Illinois Medical District

Find the best Illinois Medical District areas for the activities you enjoy most.

Downtown Chicago

Known for its fascinating museums, stunning river views and gorgeous architecture, there's plenty to explore in Downtown Chicago. Top attractions like Navy Pier and Michigan Avenue are major draws. Catch the metro at State Station or Clark-Lake Station to see more of the city.

Magnificent Mile

Are you interested in fascinating museums, panoramic lake views and popular shops? A visit to Magnificent Mile might be the perfect thing. You can also explore top sights like Michigan Avenue and Chicago Water Tower.

The Loop

Michigan Avenue and Lake Michigan are a few top attractions in The Loop. Hop around the city on the metro at Washington Station or Lake Station and check out the area's fascinating museums, popular shops and acclaimed art galleries.

River North

Known for its fantastic nightlife, stunning river views and popular shops, there's plenty to explore in River North. Top attractions like Merchandise Mart and Bally's Casino Chicago are major draws. Catch the metro at Merchandise Mart Station or Chicago Station (Brown Line) to see more of the city.

Lincoln Park

Known for its ample dining options and fantastic lake views, there's plenty to explore in Lincoln Park. You can visit top attractions like Lake Michigan and Lincoln Hall, and jump on the metro at Fullerton Station or Armitage Station to see more of the city.

Top Illinois Medical District Hotel Reviews

Frequently asked questions

What's it like in Illinois Medical District?
Guests are sure to enjoy their time checking out all that Chicago's Illinois Medical District neighbourhood has to offer.
How many hotels are there in the Illinois Medical District area?
If you're searching for places to stay in Chicago, choose from one of Expedia's 17 hotels and other accommodation options in Illinois Medical District.
If I need to cancel my hotel reservation in Illinois Medical District, will I receive a refund?
Yes, most room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the top deals on offer in Illinois Medical District.
What can I see and do in this Chicago neighbourhood?
Don't miss favourite places to visit in the surrounding area, such as United Center, Soldier Field and Michigan Avenue. Malcolm X College and Michael Jordan Statue are also worth a visit when you're out sightseeing in Chicago.
How can I get around Illinois Medical District and the greater Chicago area?
Ready to get out and explore the city? Polk Station (Pink Line) is the closest metro station.