La Jolla Mesa Holidays

Book a Hotel + Flight or Car together to unlock savings

Where to stay in La Jolla Mesa

Find the best La Jolla Mesa areas and neighborhoods for the activities you enjoy most. Learn more about La Jolla Mesa
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La Jolla Shores

1 out of top 10 points of interest in this area

While visiting La Jolla Shores, you might make a stop by sights like La Jolla Beach and Birch Aquarium.

Find hotels in La Jolla Shores

Top hotels in La Jolla Mesa

Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
Fully refundableReserve now, pay when you stay
The price is 2.796.925 ₫ per night from 4 Jan to 5 Jan
2.796.925 ₫
4.162.590 ₫ total
4 Jan - 5 Jan 2026
includes taxes & fees
8.2/10 Very Good! (3,158 reviews)
Great hotel! Enjoyed our rooms and the staff was very accommodating to our party with two small children.

Reviewed on 17 Dec 2025

Sheraton San Diego Resort
Lafayette Hotel & Club

Lafayette Hotel & Club

4 out of 5
2223 El Cajon Blvd San Diego CA
Fully refundableReserve now, pay when you stay
The price is 6.028.196 ₫ per night from 7 Jan to 8 Jan
6.028.196 ₫
6.917.355 ₫ total
7 Jan - 8 Jan 2026
includes taxes & fees
9.2/10 Wonderful! (1,341 reviews)
My favorite hotel in San Diego. Staff is always helpful, kind and professional. The rooms are comfortable, clean, eclectic and possibly the best minibar selection of top shelf products anywhere. The property invites you to discover and play and socialize. The bar and food programs are superb.

Reviewed on 17 Dec 2025

Lafayette Hotel & Club
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
Fully refundableReserve now, pay when you stay
The price is 2.864.813 ₫ per night from 24 Dec to 25 Dec
2.864.813 ₫
3.321.607 ₫ total
24 Dec - 25 Dec
includes taxes & fees
8.8/10 Excellent! (728 reviews)
Breakfast buffet was good. Room was clean. Friendly and helpful staff. San Diego was beautiful!

Reviewed on 13 Dec 2025

The DEXTRO Little Italy, BW Premier Collection
See all 9,149 properties in La Jolla Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a La Jolla Mesa holiday package cost?
Maybe less than you might think — from a low , as a matter of fact! By bundling flights, hotels and car rentals into your own custom-made travel package, your La Jolla Mesa escape is only clicks away.
How do I get a cheap travel package to La Jolla Mesa?
Search for flights that fit your busy schedule, add a hotel room to your booking and watch the savings stack up with a La Jolla Mesa holiday package. It's that easy! From hotels and flights to activities and rental cars, Expedia is where your cheap getaway begins. And with over 550 airlines and 1null000null000 hotel options around the globe to choose from, you'll never be short of choice.
Where should I stay in La Jolla Mesa?
Make sightseeing a breeze by staying close to La Jolla Mesa's iconic attractions. La Jolla Cove and University of California, San Diego are two visitor favourites.
What are the top hotels in La Jolla Mesa?
Get your escape off to a great start by booking a stay at Very Private Gated Villa - 2 Master Suites - Ocean. It's one of most sought-after hotels in La Jolla Mesa. Another leading option is Newly Remodeled With Views Of Downtown Ocean And Bay.
How far in advance should I book my La Jolla Mesa holiday?
It's tricky picking the perfect time for airfares, but we generally say the earlier, the better. Plenty of international journeys on Expedia become available to compare up to 12 months in advance. If you can't book ahead, don't despair. Bargain prices occasionally appear just weeks before departure dates.
What does an Expedia La Jolla Mesa travel package include?
With Expedia, you can choose any combination of flights, hotels and car rentals to build your perfect La Jolla Mesa package. Once you've made your booking, you can add on the fun stuff like activities and tours. Don't forget — the more you bundle, the more you stand to save!
What should I know before booking a La Jolla Mesa travel package?
A travel package can be customized for your budget and is a great way to make your budget go further. What you include is completely up to you. Hotels, rental cars and flights — mix and match whatever combination works with your plans.
Can I choose my airline with a La Jolla Mesa Expedia holiday package?
Yes, of course. Expedia has access to more than 550 partner airlines all over the world, so fly with the carrier that suits your travel needs.
If I'm not able to travel, can I cancel my La Jolla Mesa holiday package?
We totally understand that life doesn't always go according to plan. If you've booked a La Jolla Mesa holiday package and need to cancel or amend it, we can help. We suggest taking a look at our Customer Service Portal first for information. But in general, if you've taken out your package within 24 hours, you may be able to cancel and rebook at no cost. If it's more than 24 hours, your hotel, airline or car rental company may impose a fee.

Popular places to visit

La Jolla Cove as well as a small group of people

La Jolla Cove

If a restful holiday is part of your travel plans, La Jolla Cove might be the perfect place to visit during your trip to La Jolla. While you're in the area, stroll along the seaside.

La Jolla Cove
University of California, San Diego

University of California, San Diego

Enjoy the student vibe when you visit University of California, San Diego during your travels in La Jolla. Discover the beautiful sunsets in this walkable area or enjoy its surfing spots.

University of California, San Diego
Birch Aquarium featuring marine life as well as a small group of people

Birch Aquarium

Take the family to visit the sea animals who live in Birch Aquarium during your trip to La Jolla. Wander the seaside or discover the area's beautiful sunsets.

Birch Aquarium