Search Hotels in La Jolla Mesa, La Jolla

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15 Dec - 16 Dec
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16 Dec - 17 Dec
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19 Dec - 21 Dec
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26 Dec - 28 Dec

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Our top choices for La Jolla Mesa hotels

Lobby lounge
The Bristol Hotel San Diego

The Bristol Hotel San Diego

The Bristol Hotel San Diego
3.5 star property
14.2 km from La Jolla Mesa
8.6 out of 10, Excellent, (1452)
"So clean, Very Nice staff, convenient location ! "
United States
Cindy
The Bristol Hotel San Diego
Meeting facility
The Westin San Diego Bayview

The Westin San Diego Bayview

The Westin San Diego Bayview
4.0 star property
14 km from La Jolla Mesa
8.6 out of 10, Excellent, (1064)
"I loved the hotel rooms bar area jacuzzi area everything was great it was in a pretty location will definitely come back "
United States
Alliyah
The price is 3.556.706 ₫
4.886.463 ₫ total
includes taxes & fees
22 Dec - 23 Dec
The Westin San Diego Bayview
Outdoor pool, open 7:00 AM to 10:00 PM, pool cabanas (surcharge)
San Diego Mission Bay Resort

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
6.1 km from La Jolla Mesa
8.4 out of 10, Very good, (1311)
"great stay! Food was great and my kids loved the pool and location"
United States
ANDREA
The price is 3.095.282 ₫
4.743.791 ₫ total
includes taxes & fees
16 Dec - 17 Dec
San Diego Mission Bay Resort
Exterior
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
14.5 km from La Jolla Mesa
9.0 out of 10, Wonderful, (2872)
"Great Location....tons of walking from the hotel Front desk were very nice and polite will be coming back for sure "
United States
Carlos
The price is 4.630.032 ₫
6.801.759 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Manchester Grand Hyatt San Diego
3 restaurants, breakfast, lunch, dinner served; Regional cuisine
Wyndham San Diego Bayside

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
13.5 km from La Jolla Mesa
8.4 out of 10, Very good, (6064)
"Always an amazing stay"
United States
Jana
The price is 3.555.391 ₫
4.885.201 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Wyndham San Diego Bayside
2 outdoor pools, open 6 AM to 10:00 PM, pool cabanas (surcharge)
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
4.0 star property
14.8 km from La Jolla Mesa
9.2 out of 10, Wonderful, (1949)
"Great hotel"
United States
Farzana
The price is 4.182.813 ₫
6.233.248 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Marriott Marquis San Diego Marina
View from room
Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy
4.0 star property
13.6 km from La Jolla Mesa
9.0 out of 10, Wonderful, (100)
"It was a nice place to stay at"
United States
Eric
The price is 2.893.770 ₫
3.355.181 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Courtyard by Marriott San Diego Downtown Little Italy
Outdoor pool, pool loungers
Hilton San Diego Bayfront

Hilton San Diego Bayfront

Hilton San Diego Bayfront
4.0 star property
15.5 km from La Jolla Mesa
8.6 out of 10, Excellent, (1865)
"Enjoyed my stay"
United States
Brandon
The price is 2.805.642 ₫
4.543.413 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton San Diego Bayfront
Lobby
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
4.0 star property
10.3 km from La Jolla Mesa
9.2 out of 10, Wonderful, (2952)
"Friendly, staff was very helpful, great size rooms, and over all was an amazing stay"
United States
Naya
The price is 4.002.610 ₫
4.600.800 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Legacy Resort Hotel & Spa
2 outdoor pools, a heated pool, pool loungers
The Dana on Mission Bay

The Dana on Mission Bay

The Dana on Mission Bay
3.5 star property
6 km from La Jolla Mesa
9.0 out of 10, Wonderful, (3925)
"Always love staying here. Staff was very courteous and the rooms very clean. "
United States
Eric
The price is 3.656.673 ₫
4.729.302 ₫ total
includes taxes & fees
16 Dec - 17 Dec
The Dana on Mission Bay
Lobby
Gaslamp Plaza Suites

Gaslamp Plaza Suites

Gaslamp Plaza Suites
3.5 star property
14.6 km from La Jolla Mesa
9.0 out of 10, Wonderful, (1014)
"Yes everything was great I will stay there again."
United States
Sergio
The price is 3.130.533 ₫
3.560.982 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Gaslamp Plaza Suites
Front of property
The Sofia Hotel

The Sofia Hotel

The Sofia Hotel
3.5 star property
14.2 km from La Jolla Mesa
8.4 out of 10, Very good, (1660)
"Great location and history to the hotel "
United States
Stephanie
The Sofia Hotel
5 outdoor pools, a heated pool, pool umbrellas, pool loungers
Paradise Point Resort & Spa

Paradise Point Resort & Spa

Paradise Point Resort & Spa
4.0 star property
5 km from La Jolla Mesa
8.6 out of 10, Excellent, (2353)
"Great stay, top tier service and excellent customer care "
Canada
Meriem
The price is 3.402.810 ₫
5.303.526 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Paradise Point Resort & Spa
Lobby
Margaritaville Hotel San Diego Gaslamp Quarter

Margaritaville Hotel San Diego Gaslamp Quarter

Margaritaville Hotel San Diego Gaslamp Quarter
4.0 star property
15.1 km from La Jolla Mesa
9.0 out of 10, Wonderful, (1163)
"Amenities and location were great. "
United States
Julie
The price is 4.001.295 ₫
5.706.840 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Margaritaville Hotel San Diego Gaslamp Quarter
Restaurant
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
3.0 star property
15.1 km from La Jolla Mesa
9.0 out of 10, Wonderful, (1229)
"Very nice clean room and amenities and staff was pleasant and we love the location. "
United States
Arnold
The price is 3.606.164 ₫
4.181.166 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Exterior
Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley
2.5 star property
9.5 km from La Jolla Mesa
8.8 out of 10, Excellent, (1286)
"Hotel was very clean and the staff was very friendly"
United States
Norma
The price is 2.462.335 ₫
2.830.331 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Hampton Inn San Diego/Mission Valley
Standard Room, 1 King Bed, Non Smoking, Bay View | Premium bedding, pillow-top beds, in-room safe, desk
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
13.7 km from La Jolla Mesa
8.8 out of 10, Excellent, (738)
"Friendly staff and clean rooms. "
Canada
Justine
The price is 2.714.882 ₫
3.147.770 ₫ total
includes taxes & fees
28 Dec - 29 Dec
The DEXTRO Little Italy, BW Premier Collection
Exterior
Bay Club Hotel & Marina

Bay Club Hotel & Marina

Bay Club Hotel & Marina
3.5 star property
11.8 km from La Jolla Mesa
9.2 out of 10, Wonderful, (3186)
"Great stay and location!"
United States
Jason
The price is 3.243.653 ₫
3.728.417 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Bay Club Hotel & Marina
Premium bedding, pillow-top beds, desk, laptop workspace
Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
15 km from La Jolla Mesa
9.4 out of 10, Exceptional, (1003)
"Great location "
United States
Mohammad
The price is 2.341.323 ₫
3.474.891 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Staypineapple, Hotel Z, Gaslamp San Diego
Room, 2 Queen Beds (Trendy, Firepit) | Lobby
Town and Country San Diego

Town and Country San Diego

Town and Country San Diego
4.0 star property
10.1 km from La Jolla Mesa
8.6 out of 10, Excellent, (1325)
"Clean room, friendly staff."
United States
Gail
The price is 3.779.001 ₫
5.251.628 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Town and Country San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in La Jolla Mesa

Find the best La Jolla Mesa areas for the activities you enjoy most.

La Jolla Shores

While visiting La Jolla Shores, you might make a stop by sights like La Jolla Beach and Birch Aquarium.

La Jolla Cove showing rugged coastline and general coastal views as well as a small group of people

Village of La Jolla

While visiting Village of La Jolla, you might make a stop by sights like La Jolla Cove and Museum of Contemporary Art San Diego.

Torrey Pines

Pristine beaches, ample dining options, and top golf courses are just a few top things to explore in Torrey Pines. A visit to Black's Beach or Torrey Pines Golf Course might round out your trip, and you can jump aboard the metro at UC San Diego Central Campus Station or VA Medical Center Station to get around town.

Country Club

Country Club might not have many top sights, but La Jolla Cove and Mount Soledad National Veterans Memorial are two attractions nearby that you can check out.

La Jolla

Beach Barber Tract

If you're spending some time in Beach Barber Tract, Windansea Beach and Marine Street Beach are top sights worth seeing.

Top La Jolla Mesa Hotel Reviews

Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

10/10 Excellent
"Clean rooms, friendly staff"
Marie 1-night trip
Posted 10 hours ago
Courtyard by Marriott San Diego Downtown Little Italy

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Frequently asked questions

What is La Jolla Mesa like?
Travellers to La Jolla's La Jolla Mesa neighbourhood will be sure to enjoy a stay here.
How many hotels will I be able to find in the La Jolla Mesa area?
If you're searching for places to stay in La Jolla, choose from one of Expedia's 15 hotels and other accommodation options in La Jolla Mesa.
If I need to cancel my hotel reservation in La Jolla Mesa, will I receive a refund?
Yes! Most hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to review the best options available in La Jolla Mesa.
What are the top things to see and do in La Jolla Mesa?
Tourmaline Surfing Park, Bird Rock and Pacific Beach are just a few of the places to visit in and around La Jolla Mesa. While you're out sightseeing, Crystal Pier and Mount Soledad National Veterans Memorial are a couple of additional sights to visit in La Jolla.