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11 Dec - 12 Dec
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Our top choices for La Jolla Mesa hotels

Room, 1 King Bed with Sofa bed, Marina View | View from room
Sheraton San Diego Resort

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
11.5 km from La Jolla Mesa
8.2 out of 10, Very good, (3174)
"Great stay! "
United States
Melissa
The price is 2.477.558 ₫
3.796.681 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Sheraton San Diego Resort
Outdoor pool, pool loungers
Hilton San Diego Bayfront

Hilton San Diego Bayfront

Hilton San Diego Bayfront
4.0 star property
15.5 km from La Jolla Mesa
8.6 out of 10, Excellent, (1856)
"Enjoyed my stay"
United States
Brandon
The price is 2.648.879 ₫
4.364.424 ₫ total
includes taxes & fees
20 Dec - 21 Dec
Hilton San Diego Bayfront
Outdoor pool, open 7:00 AM to 10:00 PM, pool cabanas (surcharge)
San Diego Mission Bay Resort

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
6.1 km from La Jolla Mesa
8.4 out of 10, Very good, (1309)
"great stay! Food was great and my kids loved the pool and location"
United States
ANDREA
The price is 3.101.165 ₫
4.752.695 ₫ total
includes taxes & fees
14 Dec - 15 Dec
San Diego Mission Bay Resort
Standard Room, 1 King Bed, Non Smoking, Bay View | Premium bedding, pillow-top beds, in-room safe, desk
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
13.7 km from La Jolla Mesa
8.8 out of 10, Excellent, (727)
"Great little boutique hotel ! Friendly staff as well"
Canada
Caroll
The price is 2.576.621 ₫
2.987.463 ₫ total
includes taxes & fees
14 Dec - 15 Dec
The DEXTRO Little Italy, BW Premier Collection
Hypo-allergenic bedding, in-room safe, desk, iron/ironing board
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
14.5 km from La Jolla Mesa
9.0 out of 10, Wonderful, (2870)
"It was nice and the bar up top was great"
United States
Brent
The price is 4.638.832 ₫
6.814.602 ₫ total
includes taxes & fees
13 Dec - 14 Dec
Manchester Grand Hyatt San Diego
Exterior
Comfort Inn San Diego Old Town

Comfort Inn San Diego Old Town

Comfort Inn San Diego Old Town
2.5 star property
9.5 km from La Jolla Mesa
8.2 out of 10, Very good, (1912)
"Efficient check in, clean rooms and great breakfast."
Canada
Wendy
The price is 2.128.328 ₫
2.446.405 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Inn San Diego Old Town
Reception
Best Western Plus Island Palms Hotel & Marina

Best Western Plus Island Palms Hotel & Marina

Best Western Plus Island Palms Hotel & Marina
3.0 star property
11.9 km from La Jolla Mesa
8.8 out of 10, Excellent, (1554)
"Every time i have stayed here everything is always clean...no complaints!"
United States
Joseline
The price is 3.015.241 ₫
3.465.869 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Best Western Plus Island Palms Hotel & Marina
Terrace/patio
Wyndham San Diego Bayside

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
13.5 km from La Jolla Mesa
8.4 out of 10, Very good, (6045)
"Always an amazing stay"
United States
Jana
The price is 3.562.149 ₫
4.894.487 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Wyndham San Diego Bayside
Courtyard
DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar
4.0 star property
13.2 km from La Jolla Mesa
8.4 out of 10, Very good, (1868)
"The room had a great view of the pool and staff was very friendly! "
United States
eva
The price is 2.593.529 ₫
2.955.197 ₫ total
includes taxes & fees
21 Dec - 22 Dec
DoubleTree by Hilton San Diego - Del Mar
Lobby
Fairfield Inn & Suites by Marriott San Diego Pacific Beach

Fairfield Inn & Suites by Marriott San Diego Pacific Beach

Fairfield Inn & Suites by Marriott San Diego Pacific Beach
2.5 star property
4.3 km from La Jolla Mesa
9.0 out of 10, Wonderful, (798)
"good place to stay"
United States
Sisi
The price is 2.609.343 ₫
2.999.309 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Fairfield Inn & Suites by Marriott San Diego Pacific Beach
Terrace/patio
Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley
2.5 star property
9.5 km from La Jolla Mesa
8.8 out of 10, Excellent, (1277)
"Room was clean,buffet bkfast was good,staff were friendly & helpful!"
United States
Barry
The price is 2.572.443 ₫
2.956.896 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn San Diego/Mission Valley
Premium bedding, pillow-top beds, desk, laptop workspace
Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
15 km from La Jolla Mesa
9.4 out of 10, Exceptional, (1000)
"Great location "
United States
Mohammad
The price is 2.345.773 ₫
3.481.523 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Staypineapple, Hotel Z, Gaslamp San Diego
Meeting facility
The Westin San Diego Bayview

The Westin San Diego Bayview

The Westin San Diego Bayview
4.0 star property
14 km from La Jolla Mesa
8.6 out of 10, Excellent, (1060)
"I loved the hotel rooms bar area jacuzzi area everything was great it was in a pretty location will definitely come back "
United States
Alliyah
The price is 3.563.466 ₫
4.895.750 ₫ total
includes taxes & fees
19 Dec - 20 Dec
The Westin San Diego Bayview
Lobby
Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
8 km from La Jolla Mesa
7.4 out of 10, Good, (4110)
"Clean rooms and friendly staff."
United States
Aniket
The price is 2.228.484 ₫
2.561.530 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Wyndham Garden San Diego Near SeaWorld
Reception
Kings Inn San Diego

Kings Inn San Diego

Kings Inn San Diego
2.5 star property
10 km from La Jolla Mesa
8.8 out of 10, Excellent, (3563)
"Room was very clean, and the breakfast was good"
United States
Roxana
The price is 1.973.217 ₫
2.264.266 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Kings Inn San Diego
Courtyard
Leucadia Beach Inn

Leucadia Beach Inn

Leucadia Beach Inn
2.5 star property
28.5 km from La Jolla Mesa
9.4 out of 10, Exceptional, (1001)
"We love this property. Love everything about Leucadia Beach Inn."
United States
Susie M
The price is 2.348.409 ₫
2.583.250 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Leucadia Beach Inn
2 outdoor pools, open 6 AM to 10:00 PM, pool cabanas (surcharge)
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
4.0 star property
14.8 km from La Jolla Mesa
9.2 out of 10, Wonderful, (1942)
"Great hotel"
United States
Farzana
The price is 4.190.763 ₫
6.245.094 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Marriott Marquis San Diego Marina
Exterior
Hilton Garden Inn San Diego Old Town/SeaWorld Area

Hilton Garden Inn San Diego Old Town/SeaWorld Area

Hilton Garden Inn San Diego Old Town/SeaWorld Area
3.0 star property
8.6 km from La Jolla Mesa
8.6 out of 10, Excellent, (1284)
"Good location, the room was specious and clean. We really enjoyed our stay!"
United States
Yana
The price is 3.141.754 ₫
3.611.172 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton Garden Inn San Diego Old Town/SeaWorld Area
Desk, blackout curtains, iron/ironing board, cots/infant beds
Best Western Yacht Harbor Hotel

Best Western Yacht Harbor Hotel

Best Western Yacht Harbor Hotel
2.5 star property
10.7 km from La Jolla Mesa
8.6 out of 10, Excellent, (1627)
"The breakfast options were good and the staff were very helpful."
Canada
Gail or Rob
The price is 2.585.885 ₫
2.967.303 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Best Western Yacht Harbor Hotel
Standard Room, 2 Queen Beds | Pillow-top beds, individually decorated, individually furnished, desk
GreenTree Inn San Diego Mission Bay

GreenTree Inn San Diego Mission Bay

GreenTree Inn San Diego Mission Bay
2.5 star property
4 km from La Jolla Mesa
8.0 out of 10, Very good, (1855)
"Courteous staff and clean room. "
United States
Rachel
The price is 2.319.432 ₫
2.666.071 ₫ total
includes taxes & fees
16 Dec - 17 Dec
GreenTree Inn San Diego Mission Bay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in La Jolla Mesa

Find the best La Jolla Mesa areas for the activities you enjoy most.

La Jolla Shores

While visiting La Jolla Shores, you might make a stop by sights like La Jolla Beach and Birch Aquarium.

La Jolla Cove showing rugged coastline and general coastal views as well as a small group of people

Village of La Jolla

While visiting Village of La Jolla, you might make a stop by sights like La Jolla Cove and Museum of Contemporary Art San Diego.

Torrey Pines

Pristine beaches, ample dining options, and top golf courses are just a few top things to explore in Torrey Pines. A visit to Black's Beach or Torrey Pines Golf Course might round out your trip, and you can jump aboard the metro at UC San Diego Central Campus Station or VA Medical Center Station to get around town.

Country Club

Country Club might not have many top sights, but La Jolla Cove and Mount Soledad National Veterans Memorial are two attractions nearby that you can check out.

La Jolla

Beach Barber Tract

If you're spending some time in Beach Barber Tract, Windansea Beach and Marine Street Beach are top sights worth seeing.

Top La Jolla Mesa Hotel Reviews

Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld

10/10 Excellent
"Leigh at the front desk."
Randolph 1-night trip
Posted 2 days ago
Hampton Inn & Suites by Hilton San Diego SeaWorld

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Frequently asked questions

What is La Jolla Mesa like?
Travellers to La Jolla's La Jolla Mesa neighbourhood will be sure to enjoy a stay here.
How many hotels will I be able to find in the La Jolla Mesa area?
If you're searching for places to stay in La Jolla, choose from one of Expedia's 15 hotels and other accommodation options in La Jolla Mesa.
If I need to cancel my hotel reservation in La Jolla Mesa, will I receive a refund?
Yes! Most hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to review the best options available in La Jolla Mesa.
What are the top things to see and do in La Jolla Mesa?
Tourmaline Surfing Park, Bird Rock and Pacific Beach are just a few of the places to visit in and around La Jolla Mesa. While you're out sightseeing, Crystal Pier and Mount Soledad National Veterans Memorial are a couple of additional sights to visit in La Jolla.