The Best Hotels in Lake Nona Medical City, Orlando - 2026 Updated Prices

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Where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas for the activities you enjoy most.

The entrance to Aquatica with colorful signage and a water slide.

International Drive District

Visitors to International Drive District rave about its breathtaking beach views, exciting theme parks and popular shops. You might also want to make some time to see Orange County Convention Center or Aquatica while you're exploring the neighbourhood.

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The entrance to the Hollywood Studios area with a large sign and distinctive architecture.

Bay Lake

Exciting theme parks plentiful wildlife and top sights from Epcot® to Walt Disney World® Resort – discover Bay Lake, a destination also famous for its entertainment.

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A golf course with bunkers, water hazards, and a large lake.

Reunion

The top golf courses and fun-filled water parks are top of the list for many visitors to Reunion. A stop by Reunion Resort Golf Course or Jack Nicklaus Course might round out your trip.

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A large Ferris wheel with blue lighting, surrounded by a parking lot and buildings.

Champions Gate

Ample dining options and top golf courses are well-reviewed features of Champions Gate. Make a stop by top sights like ChampionsGate Golf Club while you're exploring the area.

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A roller coaster at Universal Orlando Resort, featuring a tall palm tree and a clear blue sky.

Florida Center

If you're spending some time in Florida Center, Universal Orlando Resort and Universal Studios Florida are top sights worth seeing.

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Top Lake Nona Medical City Hotel Reviews

Kompose Boutique Resort at Theme Parks

10/10 Excellent

"Amazing experience"

Universal's Cabana Bay Beach Resort

10/10 Excellent

"Enjoyed our stay. Staff were super helpful with extending our stay and linking the reservations. The property was clean and well maintained. Was not aware of having to pay $26 a day to park on the property. I was also looking forward to the lazy river but was also not aware that we had to pay for a tube to float. The tubes were reasonably priced but you can also bring your own tubes. This might have been something I overlooked in the hotel write up just a fair warning to others looking to stay here"

Holiday Inn & Suites Orlando SW - Celebration Area by IHG

8/10 Good

"Check in was easy. Staff were friendly. Hotel property is close to a lot of restaurants and grocery stores. Room was clean and the AC works great. However the pool closes at 10, would be cool if it closed at midnight. Breakfast is only from 6-10am which I believe would be more convenient to stay open until 12pm. Our shower hot water never got hot only stayed Luke warm. And you have to request turndown service you would think with a resort fee you would automatically get that daily. And the washers and dryers are kind of a mess with the wifi I had to tap my card around 10x on each machine to get them to work. Overall this hotel is a 7/10 and is very close to the theme parks."

Holiday Inn Resort Orlando Suites - Waterpark by IHG

8/10 Good

"As we arrived we checked in there was a little bit of a wait some people looked a bit upset. Then we went to get in our swimsuits to play at the water park that we booked this hotel for. We took our 2 year old to the Waterpark area to find out it was closed my little was very upset and has to deal with that so we go to see what was going on. Everyone was very nice to us and we talk to a man named Dana very very nice man. He comped our first night for us and bought us all ice cream our toddler was then happy. The rest of the say was very nice they reopened the Waterpark an hour early then close an hour later, because it was closed the night before. Overall we had a pretty good stay And had a great time The room was clean. The bed was comfy. 4 out of 5 stars for me."

Frequently asked questions

What's it like in Lake Nona Medical City?

Lake Nona Medical City is a neighbourhood that travellers like for its restaurants.

How many hotels will I find in Lake Nona Medical City?

Expedia has 5 Lake Nona Medical City hotels and other accommodation options, and one might make a good home base for venturing out into the greater Orlando area.

If I need to cancel my hotel reservation in Lake Nona Medical City, will I receive a refund?

Yes, the majority of hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Lake Nona Medical City.

What is there to do around this Orlando neighbourhood?

Eagle Creek Golf Club, USTA National Campus and Austin-Tindall Regional Park are just a few of the places to visit in and around Lake Nona Medical City. When you're sightseeing around the area, Lake Hart and Moss Park are a couple of other sights to visit.

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Our top choices for Lake Nona Medical City hotels

Aloft by Marriott Orlando Lake Nona

Courtyard Orlando Lake Nona

Residence Inn Orlando Lake Nona

Kompose Boutique Resort at Theme Parks

DASKK Orlando Hotel near Universal Blvd, an Ascend Collection Hotel

Hyatt Regency Orlando International Airport

Courtyard by Marriott across Universal Orlando

Hyatt House Orlando International Drive

La Quinta Inn & Suites by Wyndham Orlando Airport

EVEN Hotel Orlando International Airport by IHG

DoubleTree by Hilton Orlando Airport

Courtyard by Marriott Orlando Downtown

avid hotel Orlando International Airport by IHG

Rosen Shingle Creek

Hilton Garden Inn Orlando I-4 Millenia Blvd Mall

Margaritaville Resort Orlando with H2O Waterpark

Orlando Palms Hotel

Hyatt House Orlando Airport

Hampton Inn & Suites Orlando Airport @ Gateway Village

The Delaney Hotel

Where to stay in Lake Nona Medical City

International Drive District

Bay Lake

Reunion

Champions Gate

Florida Center

Top Lake Nona Medical City Hotel Reviews

Kompose Boutique Resort at Theme Parks

Frequently asked questions

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