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Search Hotels in Cherokee Seneca, Louisville

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13 Dec - 14 Dec
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19 Dec - 21 Dec
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26 Dec - 28 Dec

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Our top choices for Cherokee Seneca hotels

Breakfast, lunch and dinner served
Hyatt Regency Louisville

Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville, 6.4 km from Cherokee Seneca
8.8 out of 10, Excellent, (1002)
"Enjoyed our stay "
United States
Jedediah
The price is 3.051.612 ₫
3.590.527 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Hyatt Regency Louisville
Breakfast and dinner served
Hilton Garden Inn Louisville Downtown

Hilton Garden Inn Louisville Downtown

Hilton Garden Inn Louisville Downtown
3.5 star property
Downtown Louisville, 6.4 km from Cherokee Seneca
8.4 out of 10, Very good, (1006)
"Great stay! "
United States
THERESA
The price is 2.504.426 ₫
2.946.708 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Hilton Garden Inn Louisville Downtown
Property amenity
Courtyard Louisville Downtown

Courtyard Louisville Downtown

Courtyard Louisville Downtown
3.0 star property
Downtown Louisville, 6.3 km from Cherokee Seneca
8.6 out of 10, Excellent, (1001)
"Clean room, very easy check in/out, fantastic location. "
United States
Robert
The price is 2.567.037 ₫
3.020.376 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Courtyard Louisville Downtown
Lobby
Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
Downtown Louisville, 6.4 km from Cherokee Seneca
8.6 out of 10, Excellent, (1001)
"Excellent location and a great lobby bar with a top notch bourbon selection. "
United States
vincent
The price is 3.018.728 ₫
3.551.835 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Seelbach Hilton Louisville Downtown
Front of property
21c Museum Hotel Louisville

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, 7 km from Cherokee Seneca
9.2 out of 10, Wonderful, (1002)
"Staff was very kind, the art was fantastic, location was perfect to explore Whiskey Row, and we had a gorgeous room. Loved our time away there!"
United States
Tammy
The price is 3.656.673 ₫
4.434.308 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
21c Museum Hotel Louisville
Free daily buffet breakfast
SpringHill Suites by Marriott Louisville Downtown

SpringHill Suites by Marriott Louisville Downtown

SpringHill Suites by Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 5.9 km from Cherokee Seneca
8.4 out of 10, Very good, (1001)
"The staff was great and the hotel was really nice. Great place to stay."
United States
James
The price is 2.446.551 ₫
2.878.613 ₫ total
includes taxes & fees
16 Dec - 17 Dec
SpringHill Suites by Marriott Louisville Downtown
Sauna, body treatments, aromatherapy, hot stone massages
Omni Louisville Hotel

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville, 6.2 km from Cherokee Seneca
9.2 out of 10, Wonderful, (1728)
"This is a beautiful hotel in a great location. Very kind staff and helpful with directions."
United States
Bonnie
The price is 4.398.741 ₫
5.175.559 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Omni Louisville Hotel
Exterior
Courtyard by Marriott Louisville Airport

Courtyard by Marriott Louisville Airport

Courtyard by Marriott Louisville Airport
3.0 star property
7.1 km from Cherokee Seneca
9.0 out of 10, Wonderful, (329)
"Staff were very nice and airport shuttle was prompt "
United States
Alexandria
The price is 2.578.086 ₫
3.033.375 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Courtyard by Marriott Louisville Airport
Exterior
Fairfield Inn & Suites by Marriott Louisville Downtown

Fairfield Inn & Suites by Marriott Louisville Downtown

Fairfield Inn & Suites by Marriott Louisville Downtown
2.5 star property
Downtown Louisville, 6 km from Cherokee Seneca
8.2 out of 10, Very good, (1003)
"Clean rooms and friendly staff. "
United States
Reba
The price is 2.209.788 ₫
2.600.037 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Fairfield Inn & Suites by Marriott Louisville Downtown
Premium bedding, in-room safe, desk, laptop workspace
Derby City Gaming & Hotel - A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property
4.0 star property
6 km from Cherokee Seneca
9.4 out of 10, Exceptional, (1688)
"Great place to stay"
United States
april
Derby City Gaming & Hotel - A Churchill Downs Property
Dinner served
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville, 6.4 km from Cherokee Seneca
9.0 out of 10, Wonderful, (1107)
"Staff was courteous, hotel was beautiful and clean, and breakfast was amazing!"
United States
Shunskis
The price is 2.927.785 ₫
3.444.832 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Embassy Suites Louisville Downtown
Dining
Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 5.8 km from Cherokee Seneca
9.4 out of 10, Exceptional, (1002)
"All the staff we met were really nice! The rooms are clean and spacious."
United States
Kelly Anne
The price is 2.291.866 ₫
2.696.611 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Cambria Hotel Louisville Downtown-Whiskey Row
Property amenity
AC Hotel Louisville Downtown

AC Hotel Louisville Downtown

AC Hotel Louisville Downtown
3.5 star property
East Market District, 4.9 km from Cherokee Seneca
9.2 out of 10, Wonderful, (599)
"Loved the Hotel and area around the Hotel. Great shopping and restaurants"
United States
Melissa
The price is 2.481.456 ₫
2.919.681 ₫ total
includes taxes & fees
26 Dec - 27 Dec
AC Hotel Louisville Downtown
Terrace/patio
Home2 Suites By Hilton Shepherdsville Louisville South

Home2 Suites By Hilton Shepherdsville Louisville South

Home2 Suites By Hilton Shepherdsville Louisville South
3.0 star property
27.9 km from Cherokee Seneca
9.4 out of 10, Exceptional, (238)
"Nice place to spend time with family outside the rooms."
United States
Christopher
The price is 2.504.426 ₫
2.787.427 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
Home2 Suites By Hilton Shepherdsville Louisville South
Lobby
The Brown Hotel

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville, 6.4 km from Cherokee Seneca
9.4 out of 10, Exceptional, (1151)
"I loved everything about this place"
United States
Steven
The Brown Hotel
Deluxe Single Room, 1 King Bed, River View | View from room
The Grady

The Grady

The Grady
4.0 star property
Downtown Louisville, 6.8 km from Cherokee Seneca
9.4 out of 10, Exceptional, (1000)
"The location was outstanding and atmosphere was very nice."
United States
Malcolm
The price is 3.811.884 ₫
4.485.064 ₫ total
includes taxes & fees
20 Dec - 21 Dec
The Grady
Exterior
Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
Downtown Louisville, 7.1 km from Cherokee Seneca
8.8 out of 10, Excellent, (1653)
"Great place I would definitely book again"
United States
Lisa
The price is 2.157.174 ₫
2.538.130 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Holiday Inn Express & Suites Louisville Downtown by IHG
Reception
Residence Inn by Marriott Louisville Downtown

Residence Inn by Marriott Louisville Downtown

Residence Inn by Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 5.6 km from Cherokee Seneca
8.8 out of 10, Excellent, (1001)
"Clean room, great location,walkable to everything, parking in and out no hassle, very nice staff!"
United States
Russell
The price is 2.446.551 ₫
2.878.612 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Residence Inn by Marriott Louisville Downtown
Iron/ironing board, free WiFi, bed sheets
Staybridge Suites Louisville Expo Center by IHG

Staybridge Suites Louisville Expo Center by IHG

Staybridge Suites Louisville Expo Center by IHG
3.0 star property
Fairgrounds, 7.2 km from Cherokee Seneca
9.2 out of 10, Wonderful, (492)
"Check in was great, staff is amazing and room had everything you could need."
United States
Jeffrey
The price is 2.867.463 ₫
3.683.385 ₫ total
includes taxes & fees
20 Dec - 21 Dec
Staybridge Suites Louisville Expo Center by IHG
Exterior
Fairfield Inn & Suites by Marriott Louisville Shepherdsville

Fairfield Inn & Suites by Marriott Louisville Shepherdsville

Fairfield Inn & Suites by Marriott Louisville Shepherdsville
2.5 star property
19.2 km from Cherokee Seneca
9.4 out of 10, Exceptional, (405)
"Honestly the cleanest place we have stayed at in a long time . All employees were wonderful , the breakfast was great and clean ."
United States
Kenneth
The price is 2.446.551 ₫
2.723.012 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Fairfield Inn & Suites by Marriott Louisville Shepherdsville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Cherokee Seneca

Find the best Cherokee Seneca areas for the activities you enjoy most.
Louisville showing street scenes and signage as well as a small group of people

Downtown Louisville

Downtown Louisville is beloved for its fantastic nightlife. Take some time to explore sights in the area like Whiskey Row and KFC Yum Center.

Fairgrounds

While visiting Fairgrounds, you might make a stop by sights like Freedom Hall and Kentucky Kingdom.

Jeffersontown

Jeffersontown is known for its abundant dining options, and you can plan a trip to Bluegrass Indoor Karting and Jeffersontown Commons Shopping Center while you're in town.

St. Matthews

St. Matthews is noteworthy for its shopping, and you can make a stop at top attractions like Mall St. Matthews and Saint Matthews Pavilion Shopping Center.

Conrad Caldwell House showing signage and heritage elements

Old Louisville

Old Louisville is known for its ample dining options, and you can make a stop by Ohio River Valley and Conrad-Caldwell House Museum while in the area.

Top Cherokee Seneca Hotel Reviews

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Frequently asked questions

What is Cherokee Seneca like?
You'll be sure to have fun exploring Louisville's Cherokee Seneca neighbourhood.
If I need to cancel my hotel reservation in Cherokee Seneca, will I receive a refund?
Yes, you'll find most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to review the best deals in Cherokee Seneca.
What is there to do around this Louisville neighbourhood?
Peterson-Dumesnil House, Historic Frankfort Avenue and Colonel Sanders' Grave are just a few of the places to visit in and around Cherokee Seneca. Muhammad Ali Gravesite and Mid City Mall Shopping Center are also worth a visit when you're out sightseeing in Louisville.