Mayo Clinic Holidays

Book a Hotel + Flight or Car together to unlock savings

Where to stay in Mayo Clinic

Find the best Mayo Clinic areas and neighborhoods for the activities you enjoy most. Learn more about Mayo Clinic
Downtown Phoenix which includes signage and night scenes

Downtown Phoenix

3 out of top 10 points of interest in this area
4/5(25 area reviews)

Known for its ample dining options and great live music, there's plenty to explore in Downtown Phoenix. You can visit top attractions like Chase Field and PHX Arena, and jump on the metro at 12th Street - Jefferson Station or 12th Street - Washington Station to see more of the city.

Find hotels in Downtown Phoenix

Top hotels in Mayo Clinic

Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus

3 out of 5
13444 E Shea Blvd, Scottsdale, AZ
Fully refundableReserve now, pay when you stay
The price is 1.983.165 ₫ per night from 2 Aug to 3 Aug
1.983.165 ₫
2.260.214 ₫ total
2 Aug - 3 Aug
includes taxes & fees
8.2/10 Very Good! (1,008 reviews)
"Perfect for a quiet getaways and small views."

Reviewed on 26 Jul 2025

Sonesta Select Scottsdale at Mayo Clinic Campus
Talking Stick Resort

Talking Stick Resort

4 out of 5
9800 E. Talking Stick Way, Scottsdale, AZ
Fully refundableReserve now, pay when you stay
9.2/10 Wonderful! (3,615 reviews)
"Excellent Staycation when uou have visiting family. Close by family entertainment."

Reviewed on 29 Jul 2025

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Talking Stick Resort
Arizona Grand Resort & Spa

Arizona Grand Resort & Spa

4 out of 5
8000 S. Arizona Grand Parkway, Phoenix, AZ
Fully refundableReserve now, pay when you stay
The price is 2.857.435 ₫ per night from 24 Aug to 25 Aug
2.857.435 ₫
5.602.311 ₫ total
24 Aug - 25 Aug
includes taxes & fees
8.4/10 Very Good! (2,066 reviews)
"Charging somebody $10 to use the microwave when they rented a $330 suite is ridiculous"

Reviewed on 28 Jul 2025

Arizona Grand Resort & Spa
See all 12,817 properties in Mayo Clinic
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Mayo Clinic holiday package cost?
Starting from as low as , a package is your gateway to low-priced travel. Customize your Mayo Clinic trip by choosing from our extensive range of hotels, flights and rental cars.
How do I get a cheap travel package to Mayo Clinic?
Our Mayo Clinic holiday packages promise plenty of savings for the savvy globetrotter. For the best deals, simply combine your flights, hotels and activities into an affordable package. But low prices are just the beginning of your next unforgettable adventure. Book with Expedia and and you'll have over 550 airlines and 1null000null000 properties throughout the world to pick from. No matter your budget or style, there's a holiday package that's perfect for you.
Where should I stay in Mayo Clinic?
Cross Tournament Players Club of Scottsdale off your must-see list and then stay right near it. Soak up the exciting vibe around this terrific attraction and drop by whenever the mood strikes!
What are the top hotels in Mayo Clinic?
Whether you plan to stay for a night or a week in Mayo Clinic, you'll get a great night's rest at Sonesta Select Scottsdale at Mayo Clinic Campus. This option is popular with plenty of travellers.
How far in advance should I book my Mayo Clinic holiday?
Search Expedia to compare international flights as early as possible. In most cases, you can purchase a seat up to 12 months prior to departure. If it's too early for your preferred carrier, or you have to book last minute, don't despair. Cheap fares to Mayo Clinic sometimes occur within weeks of departure.
What does an Expedia Mayo Clinic travel package include?
It all depends on what sort of trip you have in the works. Mayo Clinic holiday deals can include car rentals, hotels and flights. You can mix and match to find the travel package that suits your style and budget. You can also add on activities and experiences after you've booked to score even bigger discounts.
What should I know before booking a Mayo Clinic travel package?
When you book your flights, hotels and car rentals together, you'll walk away with awesome discounts. Whether you're planning a beach break in a villa or want to stay in a fancy hotel in the city, Expedia will help make it happen.
Can I choose my airline with a Mayo Clinic Expedia holiday package?
You can, and with over 550 airlines to choose from all over the world, you've got lots of choice. Take a look at the available options and find out which airline fits your budget and needs.
If I'm not able to travel, can I cancel my Mayo Clinic holiday package?
You sure can, and we'll help you every step of the way. You may be able to cancel and rebook your Mayo Clinic holiday package at no cost if you booked in the last 24 hours. But you may incur a fee from your hotel, airline or car rental company if you booked more than 24 hours ago. If your travel plans suddenly change, have a look at our Customer Service Portal for further information.

Popular places to visit

Phoenix Convention Center

Phoenix Convention Center

3.5/5(2 reviews)

During your trip, find out what's happening in Phoenix Convention Center, a top convention centre in Phoenix. Experience the fascinating museums and acclaimed theatre scene in this vibrant area.

Phoenix Convention Center
Chase Field

Chase Field

4.5/5(10 reviews)

Catch an event at Chase Field and enjoy other activities in Phoenix such as golfing.In the area, take in the fascinating museums and desert landscapes.

Chase Field
State Farm Stadium

State Farm Stadium

5/5(4 reviews)

Catch an event at State Farm Stadium during your trip to Glendale. Experience the lively festivals or attend a football match in this culturally rich area.

State Farm Stadium