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Our top choices for Mayo Clinic hotels

Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus
3.0 star property
Mayo Clinic
8.2 out of 10, Very good, (1,067 reviews)
"Very clean, comfortable room. Quiet area and easy access to main road. Very comfortable bed. Would stay again."
United States
Efrain
The price is 2.602.512 ₫
2.966.083 ₫ total
includes taxes & fees
12 Apr - 13 Apr
Sonesta Select Scottsdale at Mayo Clinic Campus

Surestay by Best Western Phoenix Airport near Downtown

Surestay by Best Western Phoenix Airport near Downtown
2.5 star property
25.5 km from Mayo Clinic
8.4 out of 10, Very good, (1,860 reviews)
"Clean rooms, close to the airport."
United States
Sharon
The price is 3.734.600 ₫
4.222.712 ₫ total
includes taxes & fees
19 Apr - 20 Apr
Surestay by Best Western Phoenix Airport near Downtown

Drury Inn & Suites Phoenix Airport

Drury Inn & Suites Phoenix Airport
3.0 star property
27.7 km from Mayo Clinic
9.6 out of 10, Exceptional, (2,394 reviews)
"Clean rooms, great breakfast "
United States
Crystal
The price is 3.865.837 ₫
4.371.101 ₫ total
includes taxes & fees
6 Apr - 7 Apr
Drury Inn & Suites Phoenix Airport

Best Western Apache Junction Inn

Best Western Apache Junction Inn
2.5 star property
28.9 km from Mayo Clinic
8.8 out of 10, Excellent, (682 reviews)
"All staff was excellent, property clean"
United States
Brian
The price is 4.205.817 ₫
4.689.402 ₫ total
includes taxes & fees
30 Mar - 31 Mar
Best Western Apache Junction Inn

My Place Hotel-Phoenix East Mesa AZ

My Place Hotel-Phoenix East Mesa AZ
2.0 star property
28.2 km from Mayo Clinic
8.8 out of 10, Excellent, (110 reviews)
"Very clean room, comfy beds, nice and quiet location. "
United States
Courtney
The price is 2.853.300 ₫
3.260.466 ₫ total
includes taxes & fees
1 Apr - 2 Apr
My Place Hotel-Phoenix East Mesa AZ

Hilton Garden Inn Phoenix Airport North

Hilton Garden Inn Phoenix Airport North
3.0 star property
24.2 km from Mayo Clinic
8.8 out of 10, Excellent, (2,604 reviews)
"Close to airport and helpful staff"
United States
Michael
The price is 3.642.991 ₫
4.119.130 ₫ total
includes taxes & fees
12 Apr - 13 Apr
Hilton Garden Inn Phoenix Airport North

Fountain Park Hotel, BW Signature Collection

Fountain Park Hotel, BW Signature Collection
3.0 star property
7.2 km from Mayo Clinic
8.8 out of 10, Excellent, (1,001 reviews)
"Great place to stay. Close to everything!"
United States
Alesia
The price is 2.659.031 ₫
3.035.815 ₫ total
includes taxes & fees
7 Apr - 8 Apr
Fountain Park Hotel, BW Signature Collection

Wekopa Casino Resort

Wekopa Casino Resort
4.0 star property
10.1 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,003 reviews)
"Amazing hotel and staff!!"
United States
bryan
The price is 3.761.813 ₫
5.836.449 ₫ total
includes taxes & fees
5 Apr - 6 Apr
Wekopa Casino Resort

Hyatt Place Tempe Phoenix Airport

Hyatt Place Tempe Phoenix Airport
3.0 star property
23.5 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,084 reviews)
"Great location, the room was clean and comfortable. "
United States
DAVID
The price is 3.997.600 ₫
4.560.063 ₫ total
includes taxes & fees
6 Apr - 7 Apr
Hyatt Place Tempe Phoenix Airport

Stay7 Studios Hotel Phoenix

Stay7 Studios Hotel Phoenix
2.0 star property
29.8 km from Mayo Clinic
6.6 out of 10, (462 reviews)
"The staff was extremely friendly and helpful."
United States
Stephanie
The price is 2.812.816 ₫
3.180.451 ₫ total
includes taxes & fees
7 Apr - 8 Apr
Stay7 Studios Hotel Phoenix

Talking Stick Resort

Talking Stick Resort
4.0 star property
9 km from Mayo Clinic
9.2 out of 10, Wonderful, (4,487 reviews)
"Very nice stay"
Canada
Kelvin
The price is 4.471.589 ₫
5.847.977 ₫ total
includes taxes & fees
12 Apr - 13 Apr
Talking Stick Resort

Holiday Inn Express Hotel & Suites Phoenix North Scottsdale by IHG

Holiday Inn Express Hotel & Suites Phoenix North Scottsdale by IHG
2.5 star property
20.2 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,011 reviews)
"Clean conveniently located near shopping restaurants"
United States
Marc
The price is 3.550.500 ₫
4.014.550 ₫ total
includes taxes & fees
5 Apr - 6 Apr
Holiday Inn Express Hotel & Suites Phoenix North Scottsdale by IHG

Sentral Sol Modern

Sentral Sol Modern
4.0 star property
29.9 km from Mayo Clinic
9.4 out of 10, Exceptional, (285 reviews)
"Great place to stay. I would stay again."
United States
Andrew
The price is 3.761.813 ₫
4.996.644 ₫ total
includes taxes & fees
6 Apr - 7 Apr
Sentral Sol Modern

Home2 Suites by Hilton Phoenix Downtown

Home2 Suites by Hilton Phoenix Downtown
3.0 star property
30.3 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,286 reviews)
"Great location."
United States
Melissa
The price is 4.836.570 ₫
5.468.709 ₫ total
includes taxes & fees
8 Apr - 9 Apr
Home2 Suites by Hilton Phoenix Downtown

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
3.0 star property
Central Scottsdale, 9 km from Mayo Clinic
8.8 out of 10, Excellent, (1,882 reviews)
"The staff were so friendly and helpful. "
United States
Sharron
The price is 2.343.593 ₫
2.670.993 ₫ total
includes taxes & fees
5 Apr - 6 Apr
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Hilton Phoenix Airport

Hilton Phoenix Airport
4.0 star property
25 km from Mayo Clinic
8.8 out of 10, Excellent, (1,100 reviews)
"Staff was incredibly helpful and accomodating."
United States
Brittany
The price is 3.889.507 ₫
4.397.864 ₫ total
includes taxes & fees
6 Apr - 7 Apr
Hilton Phoenix Airport

Tempe Oasis

Tempe Oasis
2.0 star property
19.7 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,128 reviews)
"Very nice place to stay!"
United States
Isabelle
Tempe Oasis

Marriott Phoenix Airport

Marriott Phoenix Airport
3.5 star property
22.7 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,000 reviews)
"Staff was courteous and beds were super comfy."
United States
Nancy
The price is 5.181.365 ₫
5.858.570 ₫ total
includes taxes & fees
10 Apr - 11 Apr
Marriott Phoenix Airport

Hyatt Place Phoenix/Mesa

Hyatt Place Phoenix/Mesa
3.0 star property
17.9 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,774 reviews)
"This hotel was clean with a friendly staff and conveniently located near many restaurants and Cubs spring training."
United States
Gretchen
The price is 3.103.400 ₫
3.546.256 ₫ total
includes taxes & fees
12 Apr - 13 Apr
Hyatt Place Phoenix/Mesa

Red Roof Inn PLUS+ Tempe - Phoenix Airport

Red Roof Inn PLUS+ Tempe - Phoenix Airport
2.5 star property
25.5 km from Mayo Clinic
7.4 out of 10, Good, (1,000 reviews)
"Clean room, friendly staff easy access definitely will stay here again"
United States
kenneth
The price is 2.473.265 ₫
2.821.253 ₫ total
includes taxes & fees
29 Mar - 30 Mar
Red Roof Inn PLUS+ Tempe - Phoenix Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mayo Clinic

Find the best Mayo Clinic areas for the activities you enjoy most.

Downtown Phoenix

Known for its ample dining options and great live music, there's plenty to explore in Downtown Phoenix. You can visit top attractions like Chase Field and Mortgage Matchup Center, and jump on the metro at 12th Street - Jefferson Station or 12th Street - Washington Station to see more of the city.

Rio Verde Foothills

If you're looking for some top things to see and do in Rio Verde Foothills and surrounding area, you can visit Tom's Thumb Trail and Tonto Verde Golf Club.

Old Town

Gourmet restaurants interesting history and top sights from Scottsdale Waterfront to Western Spirit: Scottsdale's Museum of the West – discover Old Town, a destination also famous for its shopping.

Camelback East

You might take some time to check out the abundant dining options in Camelback East. Spend some time visiting top spots like Biltmore Fashion Park, and catch the metro at 44th Street - Washington Station or 50th Street Station to see more of the area.

North Phoenix

While you're in North Phoenix, take in top sights like Reach 11 Sports Complex and jump on the metro at 19th Avenue/ Dunlap Station to see more of the city.

Top Mayo Clinic Hotel Reviews

Frequently asked questions

What is Mayo Clinic like?
Travellers will be sure to find plenty to entertain them in Scottsdale's Mayo Clinic neighbourhood.
How many hotels should I expect to find in the Mayo Clinic area?
With 14 Expedia hotels and other accommodation options in Mayo Clinic to choose from, this is a good starting point for exploring the greater Scottsdale area.
If I need to cancel my hotel reservation in Mayo Clinic, will I receive a refund?
Yes! Most hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best options available in Mayo Clinic.
What is there to do around this Scottsdale neighbourhood?
A few places to visit in the area around Mayo Clinic include Eagle Mountain Golf Course, Golf Club at Eagle Mountain and SunRidge Canyon Golf Club. Make a stop at Talking Stick Resort Casino and OdySea Aquarium while you're sightseeing around the area.