Search Hotels in Medical Arts District, St. Petersburg - Clearwater

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22 Dec - 23 Dec
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23 Dec - 24 Dec
This weekend
26 Dec - 28 Dec
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2 Jan - 4 Jan

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Our top choices for Medical Arts District hotels

Outdoor pool, pool umbrellas, pool loungers
Wyndham Grand Clearwater Beach

Wyndham Grand Clearwater Beach

Wyndham Grand Clearwater Beach
4.0 star property
7.1 km from Medical Arts District
9.4 out of 10, Exceptional, (2920)
"Excellent Stay"
United States
Rob
The price is 5.408.862 ₫
7.152.771 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Wyndham Grand Clearwater Beach
Rooftop bar
Courtyard by Marriott Clearwater Beach

Courtyard by Marriott Clearwater Beach

Courtyard by Marriott Clearwater Beach
3.0 star property
7.6 km from Medical Arts District
8.8 out of 10, Excellent, (1006)
"Great location for the price."
United States
Chayamon
The price is 3.763.045 ₫
4.252.242 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Courtyard by Marriott Clearwater Beach
Exterior
RumFish Beach at TradeWinds

RumFish Beach at TradeWinds

RumFish Beach at TradeWinds
4.0 star property
21 km from Medical Arts District
8.2 out of 10, Very good, (1550)
"The staff was wonderful! The room was clean and they live entertainment with couches and fire pits right on.beach Would be excellent girls trip! "
United States
Patricia
The price is 3.055.171 ₫
5.087.820 ₫ total
includes taxes & fees
23 Dec - 24 Dec
RumFish Beach at TradeWinds
2 outdoor pools
Grand Hyatt Tampa Bay

Grand Hyatt Tampa Bay

Grand Hyatt Tampa Bay
4.0 star property
25.7 km from Medical Arts District
9.0 out of 10, Wonderful, (1140)
"Beautiful hotel and great staff! "
United States
Turquinitra
The price is 5.236.685 ₫
6.989.132 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Grand Hyatt Tampa Bay
Outdoor pool, pool cabanas (surcharge), pool umbrellas
The Saint Hotel

The Saint Hotel

The Saint Hotel
2.0 star property
20.1 km from Medical Arts District
9.6 out of 10, Exceptional, (495)
"So cute, clean, vibe-y. Great location also!! "
United States
charlene
The price is 3.596.576 ₫
5.104.593 ₫ total
includes taxes & fees
23 Dec - 24 Dec
The Saint Hotel
2 outdoor pools, a heated pool, pool loungers
Edge Hotel Clearwater Beach

Edge Hotel Clearwater Beach

Edge Hotel Clearwater Beach
3.5 star property
6.5 km from Medical Arts District
8.8 out of 10, Excellent, (1229)
"Was a great stay."
United States
Margaret
Edge Hotel Clearwater Beach
Lobby
Hyatt House Tampa Airport Westshore

Hyatt House Tampa Airport Westshore

Hyatt House Tampa Airport Westshore
3.0 star property
27.3 km from Medical Arts District
9.6 out of 10, Exceptional, (1966)
"Good location close to airport and shopping. "
United States
Michael VanHouton
The price is 3.105.170 ₫
3.524.369 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Hyatt House Tampa Airport Westshore
Terrace/patio
DoubleTree by Hilton Tampa Rocky Point Waterfront

DoubleTree by Hilton Tampa Rocky Point Waterfront

DoubleTree by Hilton Tampa Rocky Point Waterfront
4.0 star property
24.1 km from Medical Arts District
8.2 out of 10, Very good, (1004)
"This place was great staff was very friendly and helpful "
United States
Michael
The price is 3.215.167 ₫
3.649.214 ₫ total
includes taxes & fees
29 Dec - 30 Dec
DoubleTree by Hilton Tampa Rocky Point Waterfront
Rooftop terrace
Hampton Inn & Suites Clearwater Beach

Hampton Inn & Suites Clearwater Beach

Hampton Inn & Suites Clearwater Beach
3.5 star property
6.2 km from Medical Arts District
9.2 out of 10, Wonderful, (1003)
"It was a great stay! "
United States
Marisol
The price is 5.157.214 ₫
5.827.653 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
Hampton Inn & Suites Clearwater Beach
Rooftop terrace
AC Hotel Clearwater Beach

AC Hotel Clearwater Beach

AC Hotel Clearwater Beach
3.5 star property
6.8 km from Medical Arts District
9.0 out of 10, Wonderful, (954)
"Beautiful place to stay. Very comfortable. "
United States
Nicole
The price is 5.631.410 ₫
6.363.493 ₫ total
includes taxes & fees
23 Dec - 24 Dec
AC Hotel Clearwater Beach
Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, pool loungers
Comfort Inn & Suites Northeast - Gateway

Comfort Inn & Suites Northeast - Gateway

Comfort Inn & Suites Northeast - Gateway
3.0 star property
16.9 km from Medical Arts District
9.0 out of 10, Wonderful, (1004)
"Clean room and great staff"
United States
Osmany
The price is 2.818.337 ₫
3.184.722 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Comfort Inn & Suites Northeast - Gateway
Family Double Room, Pool View | In-room safe, desk, laptop workspace, blackout curtains
ChartHouse Clearwater Beach Marina Hotel

ChartHouse Clearwater Beach Marina Hotel

ChartHouse Clearwater Beach Marina Hotel
2.0 star property
7.2 km from Medical Arts District
9.6 out of 10, Exceptional, (592)
"very nice hotel "
United States
Sheldon
The price is 5.083.269 ₫
5.744.094 ₫ total
includes taxes & fees
23 Dec - 24 Dec
ChartHouse Clearwater Beach Marina Hotel
Terrace/patio
SpringHill Suites by Marriott Clearwater Beach

SpringHill Suites by Marriott Clearwater Beach

SpringHill Suites by Marriott Clearwater Beach
2.5 star property
7 km from Medical Arts District
8.8 out of 10, Excellent, (1006)
"We very much enjoyed our stay here! The staff were friendly and welcoming, the room was clean and we loved the free breakfast with a wide range of options of food and drinks. "
United States
Naomi
The price is 4.610.388 ₫
5.209.738 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
SpringHill Suites by Marriott Clearwater Beach
On the beach, white sand, beach towels, kayaking
Shephard's Beach Resort

Shephard's Beach Resort

Shephard's Beach Resort
3.5 star property
6.3 km from Medical Arts District
9.0 out of 10, Wonderful, (1462)
"Great music , food , views and vibes. "
United States
Stacey
Shephard's Beach Resort
Lobby sitting area
Avalon Hotel Downtown St. Petersburg

Avalon Hotel Downtown St. Petersburg

Avalon Hotel Downtown St. Petersburg
2.5 star property
22.4 km from Medical Arts District
9.2 out of 10, Wonderful, (1352)
"Wonderful stay, loved all the available amenities between the two hotels. "
United States
Mark
Avalon Hotel Downtown St. Petersburg
Exterior
Hyatt Place Tampa Airport/Westshore

Hyatt Place Tampa Airport/Westshore

Hyatt Place Tampa Airport/Westshore
3.0 star property
27.9 km from Medical Arts District
8.6 out of 10, Excellent, (1109)
"I enjoyed my stay and will recommend to others "
United States
Essie
The price is 3.289.375 ₫
3.733.440 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Hyatt Place Tampa Airport/Westshore
Terrace/patio
Holiday Inn Express Hotel & Suites Tampa Northwest - Oldsmar by IHG

Holiday Inn Express Hotel & Suites Tampa Northwest - Oldsmar by IHG

Holiday Inn Express Hotel & Suites Tampa Northwest - Oldsmar by IHG
2.5 star property
19.9 km from Medical Arts District
9.4 out of 10, Exceptional, (1004)
"Very nice room and wonderful breakfast "
United States
Lisa
The price is 3.105.170 ₫
3.508.843 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Holiday Inn Express Hotel & Suites Tampa Northwest - Oldsmar by IHG
Beach nearby, white sand
Fairfield Inn & Suites by Marriott Clearwater Beach

Fairfield Inn & Suites by Marriott Clearwater Beach

Fairfield Inn & Suites by Marriott Clearwater Beach
2.5 star property
8.4 km from Medical Arts District
9.0 out of 10, Wonderful, (1005)
"Very nice and accommodating staff."
United States
Yvonne
The price is 3.789.360 ₫
4.281.976 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Fairfield Inn & Suites by Marriott Clearwater Beach
Terrace/patio
Hampton Inn & Suites Tampa Airport Avion Park Westshore

Hampton Inn & Suites Tampa Airport Avion Park Westshore

Hampton Inn & Suites Tampa Airport Avion Park Westshore
2.5 star property
27.2 km from Medical Arts District
9.2 out of 10, Wonderful, (2632)
"Great staff, clean rooms and quiet."
United States
Michael
The price is 2.999.384 ₫
3.404.301 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Hampton Inn & Suites Tampa Airport Avion Park Westshore
Beach nearby, white sand
Devon Shores

Devon Shores

Devon Shores
2.5 star property
6.8 km from Medical Arts District
9.6 out of 10, Exceptional, (1253)
"The place was very clean the staff was very friendly and helpful."
United States
Gladys
The price is 3.657.785 ₫
4.133.297 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Devon Shores
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Medical Arts District

Find the best Medical Arts District areas for the activities you enjoy most.

Downtown St. Petersburg

Downtown St. Petersburg is beloved for its fantastic nightlife. Take some time to explore sights in the area like Tampa Bay and The Coliseum.

Pass-a-Grille

Pass-a-Grille is popular for its beaches, and if you're looking for more to see and do, you might think about a trip to Pass-a-Grille Beach or St. Petersburg - Clearwater Beaches.

Sand Key

If you're spending some time in Sand Key, Belleair Beach and Sand Key Park are top sights worth seeing.

Sunset Beach

Sunset Beach is noteworthy for its beaches, and you can make a stop at top attractions like Sunset Beach and St. Petersburg - Clearwater Beaches.

Clearwater featuring café lifestyle

Downtown Clearwater

If you're spending some time in Downtown Clearwater, Coachman Park and Nancy and David Bilheimer Capitol Theatre are top sights worth seeing.

Top Medical Arts District Hotel Reviews

Frequently asked questions

What is Medical Arts District like?
You'll be sure to have fun exploring Largo's Medical Arts District neighbourhood.
How many hotels are there in the Medical Arts District area?
If you're searching for places to stay in Largo, choose from one of Expedia's 12 hotels and other accommodation options in Medical Arts District.
If I need to cancel my hotel reservation in Medical Arts District, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within a 24-hour period of booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to get the best deals available in Medical Arts District.
What is there to do in this Largo neighbourhood?
The Amish Country Store, Midori Salon and Spa and Belleview Biltmore Golf Club are just a few of the places to visit in and around Medical Arts District. While you're out sightseeing, Central Park Performing Arts Center and Largo Tennis Center are a couple of additional sights to visit in Largo.