Medical Center Area Holidays

Book a Hotel + Flight or Car together to unlock savings

Photo by Gigi Aly

Where to stay in Medical Center Area

Find the best Medical Center Area areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center Area
Downtown Boston which includes a city and night scenes as well as a small group of people

Downtown Boston

4.5/5(94 area reviews)

Known for its must-see aquarium and captivating waterfront views, there's plenty to explore in Downtown Boston. Check out top attractions like Boston Massacre Site and Old State House, and jump on the metro at State St. Station or Downtown Crossing Station to see more of the city.

Find hotels in Downtown Boston

Top hotels in Medical Center Area

Seaport Hotel Boston

Seaport Hotel Boston

4 out of 5
1 Seaport Lane Boston MA
The price is 3.687.598 ₫ per night from 1 Mar to 2 Mar
3.687.598 ₫
5.180.011 ₫ total
1 Mar - 2 Mar
includes taxes & fees
9.6/10 Exceptional! (4,024 reviews)
Clean room, breakfast was good, and the front doorman very helpful

Reviewed on 21 Feb 2026

Seaport Hotel Boston
Omni Boston Hotel at the Seaport

Omni Boston Hotel at the Seaport

5 out of 5
450 Summer Street Boston MA
Fully refundableReserve now, pay when you stay
The price is 2.984.357 ₫ per night from 1 Mar to 2 Mar
2.984.357 ₫
4.533.667 ₫ total
1 Mar - 2 Mar
includes taxes & fees
9/10 Wonderful! (4,499 reviews)
The rooms were very clean and the staff was very helpful with everything we needed

Reviewed on 22 Feb 2026

Omni Boston Hotel at the Seaport
Hilton Boston Park Plaza

Hilton Boston Park Plaza

4 out of 5
50 Park Plaza Boston MA
Fully refundableReserve now, pay when you stay
The price is 3.172.892 ₫ per night from 8 Mar to 9 Mar
3.172.892 ₫
4.753.070 ₫ total
8 Mar - 9 Mar
includes taxes & fees
8.2/10 Very Good! (3,120 reviews)
Very clean, spacious rooms, great central location.

Reviewed on 18 Feb 2026

Hilton Boston Park Plaza
See all 4,184 properties in Medical Center Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Medical Centre Area holiday package cost?
From as little as , you can create your own Medical Centre Area package the way you want. Simply bundle hotels, flights and car rentals and we'll reward you with discounts.
How do I get a cheap travel package to Medical Centre Area?
Bundling your flight and hotel with Expedia won't just save precious time — it'll save you a nice amount too. A Medical Centre Area holiday package makes it simple to arrange your ideal trip. With more than 550 airlines across the world to pick from, finding flights that fit your busy schedule will be no sweat. In addition to that, we have over 1null000null000 hotels globally to choose from. Now that's what you call choice. No matter who you are, Expedia puts the world within your reach.
Where should I stay in Medical Centre Area?
Visitors come from all over the world to experience Fenway Park and TD Garden in Medical Centre Area. Stay within walking distance of these top attractions to make sightseeing easy.
What are the top hotels in Medical Centre Area?
If it's comfort and convenience you want, you can't beat The Inn at Longwood Medical. Spend your evenings relaxing here and your days roaming around Medical Centre Area's finest sights.
How far in advance should I book my Medical Centre Area holiday?
While prices change from time to time, we generally suggest booking your holiday as early as possible. Most international airfares can be compared on Expedia up to 12 months in advance. If you're booking last minute, you might still be in luck. Cheap journeys to Medical Centre Area sometimes emerge only weeks before departure.
What does an Expedia Medical Centre Area travel package include?
Packages include flights, rental cars and hotels, but you can combine any of them to create your dream Medical Centre Area escape. You can also add on fun things like activities and experiences once you've made your booking. You're in control! When you bundle your bookings with Expedia, you'll get access to discounts you won't find elsewhere.
What should I know before booking a Medical Centre Area travel package?
You can save big by bundling your hotels, airfares and rental cars. Once you've created your package, you can add on sightseeing tours or experiences. Your next awesome holiday is only a few clicks away.
Can I choose my airline with a Medical Centre Area Expedia holiday package?
You certainly can. We offer more than 550 airline partners across the globe, so fly with the carrier that's a good fit for your needs.
If I'm not able to travel, can I cancel my Medical Centre Area holiday package?
If your travel plans in Medical Centre Area have changed, it's good to know that you can amend or cancel your booking. If you made your booking within the last 24 hours, you may be eligible to receive a refund. If your booking was made more than 24 hours ago, your airline, hotel or car rental company may charge a cancellation fee. For more information, visit our Customer Service Portal.

Popular places to visit

Boston_BrighamandWomensHospital_6070043_04

Brigham and Women's Hospital

5/5(1 review)

If Brigham and Women's Hospital is what brings you to town, hopefully you'll have a chance to explore more of Boston.

Brigham and Women's Hospital
Fenway Park which includes a sporting event and night scenes as well as a large group of people

Fenway Park

4.5/5(61 reviews)

Catch an event at Fenway Park during your trip to Boston. Attend a baseball game in this walkable area.

Fenway Park
Gillette Stadium is also home to the New England Revolution, our pro soccer team. Tickets are easy to get and not crazy expensive. And there is always a section reserved for the hooligans, who keep the energy up for the whole stadium!

Gillette Stadium

3/5(2 reviews)

Catch an event at Gillette Stadium during your trip to Foxborough. Experience the area's acclaimed theatre scene and great live music.

Gillette Stadium