Search Hotels in Medical Center District, San Antonio
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Our top choices for Medical Center District hotels
San Antonio Marriott Northwest Medical Center
San Antonio Marriott Northwest Medical CenterMedical Center District
8.6 out of 10, Excellent, (1005)
"Best hotel!"
Valeria
The price is 2.438.085 ₫
2.897.299 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Fairfield Inn & Suites by Marriott San Antonio Medical Center
Fairfield Inn & Suites by Marriott San Antonio Medical CenterMedical Center District
9.0 out of 10, Wonderful, (1003)
"Everything was great, staff really kind ..."
traci
The price is 2.184.145 ₫
2.549.989 ₫ total
includes taxes & fees
31 Dec - 1 Jan 2026
SpringHill Suites by Marriott San Antonio Medical Center/NW
SpringHill Suites by Marriott San Antonio Medical Center/NWMedical Center District
8.8 out of 10, Excellent, (1001)
"good staff. good stay"
Divya
The price is 2.657.815 ₫
3.141.776 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Drury Inn & Suites San Antonio Northwest Medical Center
Drury Inn & Suites San Antonio Northwest Medical CenterMedical Center District
9.2 out of 10, Wonderful, (1291)
"Great place to stay and visit "
Harry
The price is 2.368.087 ₫
2.799.127 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NWMedical Center District
8.4 out of 10, Very good, (3128)
"Great place "
Amado
The price is 2.336.772 ₫
2.762.022 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Courtyard by Marriott Medical Center San Antonio
Courtyard by Marriott Medical Center San AntonioMedical Center District
8.8 out of 10, Excellent, (1002)
"Excellent service and very clean rooms "
Emma
The price is 2.214.407 ₫
2.617.629 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Medical Center District
Find the best Medical Center District areas for the activities you enjoy most.
Downtown San Antonio
A scenic riverfront great entertainment and top sights from Aztec Theater to San Antonio River – discover Downtown San Antonio, a destination also famous for its historic sites.
Uptown
If you're spending some time in Uptown, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.
Far West Side
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.
Stone Oak
Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista while you're in town.
Northwest Side
If you're spending some time in Northwest Side, Huebner Oaks and Convocation Center are top sights worth seeing.
Top Medical Center District Hotel Reviews
Hyatt Vacation Club at Wild Oak Ranch, San Antonio
10/10 Excellent