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Our top choices for Medical Center District hotels

Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1,008 reviews)
"The room was spacious and clean, the staff was friendly and helpful, and our stay was well spent."
United States
Dale
The price is 2.340.433 ₫
2.766.603 ₫ total
includes taxes & fees
11 Jul - 12 Jul
Courtyard by Marriott Medical Center San Antonio

San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center
3.5 star property
Medical Center District
8.6 out of 10, Excellent, (1,097 reviews)
"The Marriot from check in to check out was top notch. Ricky checked me in and was by far the most pleasant, helpful, and accommodating of any concierge I’ve ever encountered. Great stay!"
United States
Paul
The price is 3.053.082 ₫
3.627.951 ₫ total
includes taxes & fees
12 Jul - 13 Jul
San Antonio Marriott Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District
9.2 out of 10, Wonderful, (1,372 reviews)
"Price is affordable for us, is very clean and we love bed and pillows, breakfast is good."
United States
Estela
The price is 2.366.467 ₫
2.797.377 ₫ total
includes taxes & fees
12 Jul - 13 Jul
Drury Inn & Suites San Antonio Northwest Medical Center

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
Medical Center District
8.4 out of 10, Very good, (3,450 reviews)
"plenty of paking, great staff awesome jacuzzi great stay"
United States
Luz
The price is 2.335.174 ₫
2.760.134 ₫ total
includes taxes & fees
6 Jul - 7 Jul
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
Medical Center District
9.0 out of 10, Wonderful, (1,018 reviews)
"Was a great stay. "
United States
Sunanda
The price is 2.274.165 ₫
2.655.087 ₫ total
includes taxes & fees
2 Aug - 3 Aug
Fairfield Inn & Suites by Marriott San Antonio Medical Center

Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Country Inn & Suites by Radisson, San Antonio Medical Center, TX
3.0 star property
Medical Center District
7.0 out of 10, Good, (1,003 reviews)
"It was a comfortable stay"
United States
Eric
The price is 1.765.844 ₫
2.061.623 ₫ total
includes taxes & fees
26 Jul - 27 Jul
Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Park Inn by Radisson

Park Inn by Radisson
2.0 star property
Medical Center District
7.2 out of 10, Good, (1,000 reviews)
"This was our 2nd time staying and it was even better than the last. The room was very clean, nicely updated, and super comfy. The morning coffee was a hit as well. We come to SA often so this is going to be our first choice for stays. We had been on a road trip for 6 days and this was our final stop. Literally the best place we stayed."
United States
Elizabeth
The price is 1.765.844 ₫
2.061.624 ₫ total
includes taxes & fees
19 Jul - 20 Jul
Park Inn by Radisson

OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio
2.0 star property
Medical Center District
7.4 out of 10, Good, (239 reviews)
"It was quiet and clean and the staff was very friendly"
United States
Ronnie
The price is 1.472.632 ₫
1.866.560 ₫ total
includes taxes & fees
18 Jul - 19 Jul
OYO Inn & Suites Medical Center San Antonio

Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center
2.0 star property
Medical Center District
7.4 out of 10, Good, (322 reviews)
"We liked that the property was quiet and staff was courteous and helpful. We would have liked more towels in the bathroom."
United States
Alma
The price is 1.233.592 ₫
1.440.219 ₫ total
includes taxes & fees
8 Jul - 9 Jul
Studio 6 San Antonio, Tx - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center
2.0 star property
Medical Center District
6.0 out of 10, (1,000 reviews)
"The staff and the fast check in and out."
United States
José
The price is 1.248.845 ₫
1.542.057 ₫ total
includes taxes & fees
7 Jul - 8 Jul
Motel 6 San Antonio, TX - Northwest Medical Center

Flex Studios

Flex Studios
2.5 star property
Medical Center District
6.2 out of 10, (548 reviews)
"Yes I would stay again"
United States
Jasper
The price is 1.065.028 ₫
1.258.958 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Flex Studios

Atria Inn & Suites

Atria Inn & Suites
2.0 star property
Medical Center District
7.4 out of 10, Good, (300 reviews)
"The stay wasn’t HORRIBLE but it definitely wasn’t great. When we got to our room there were old clothes from previous guest in the drawers…on top of that we needed clean towels and they had nothing available. The worst part to say though is that there were some very suspicious people walking around and peeping through my truck window-I’m not sure if they were even guests. I thought the neighborhood was good but it’s actually kinda bad, so don’t expect a relaxing night. Everything else was mid...
United States
Alyssa
The price is 1.656.711 ₫
1.934.210 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Atria Inn & Suites

Studio 6 Extended Stay - San Antonio, TX - Medical Center

Studio 6 Extended Stay - San Antonio, TX - Medical Center
2.0 star property
Medical Center District
6.8 out of 10, (933 reviews)
"It was an amazing stay "
United States
Cordale
The price is 1.314.587 ₫
1.606.747 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Studio 6 Extended Stay - San Antonio, TX - Medical Center

The Westin San Antonio North

The Westin San Antonio North
4.0 star property
3.4 km from Medical Center District
8.6 out of 10, Excellent, (1,464 reviews)
"The room was clean and roomy, and the indoor pool was so relaxing like a spa, plus they have a sauna!"
United States
Cassandra
The price is 2.659.942 ₫
3.187.417 ₫ total
includes taxes & fees
19 Jul - 20 Jul
The Westin San Antonio North

Drury Plaza Hotel San Antonio North Stone Oak

Drury Plaza Hotel San Antonio North Stone Oak
3.0 star property
Stone Oak, 14.8 km from Medical Center District
9.6 out of 10, Exceptional, (1,441 reviews)
"Wonderful hotel clean , nice staff and location excellent"
United States
Maria
The price is 2.682.031 ₫
3.170.402 ₫ total
includes taxes & fees
9 Jul - 10 Jul
Drury Plaza Hotel San Antonio North Stone Oak

Hyatt Place San Antonio-Northwest/Medical Center

Hyatt Place San Antonio-Northwest/Medical Center
3.0 star property
3.7 km from Medical Center District
8.4 out of 10, Very good, (1,003 reviews)
"Clean room, easy check-in and great bfast"
United States
Dennis
The price is 2.340.433 ₫
2.798.686 ₫ total
includes taxes & fees
12 Jul - 13 Jul
Hyatt Place San Antonio-Northwest/Medical Center

InterContinental San Antonio Riverwalk by IHG

InterContinental San Antonio Riverwalk by IHG
4.5 star property
Downtown San Antonio, 11.8 km from Medical Center District
9.2 out of 10, Wonderful, (707 reviews)
"Great place to stay."
United States
Edward
The price is 4.575.678 ₫
6.509.393 ₫ total
includes taxes & fees
12 Jul - 13 Jul
InterContinental San Antonio Riverwalk by IHG

Drury Inn & Suites Near La Cantera Parkway

Drury Inn & Suites Near La Cantera Parkway
3.0 star property
La Cantera District, 9.5 km from Medical Center District
9.4 out of 10, Exceptional, (1,762 reviews)
"Everything was excellent well be staying again there"
United States
Juana
The price is 2.471.655 ₫
2.921.718 ₫ total
includes taxes & fees
26 Jul - 27 Jul
Drury Inn & Suites Near La Cantera Parkway

Hilton San Antonio Hill Country

Hilton San Antonio Hill Country
4.0 star property
Far West Side, 11.6 km from Medical Center District
8.6 out of 10, Excellent, (1,118 reviews)
"We loved staying here, will definitely be back!"
United States
Mayra
The price is 3.624.516 ₫
5.322.710 ₫ total
includes taxes & fees
12 Jul - 13 Jul
Hilton San Antonio Hill Country

Courtyard by Marriott San Antonio Six Flags at The Rim

Courtyard by Marriott San Antonio Six Flags at The Rim
3.0 star property
La Cantera District, 11 km from Medical Center District
8.8 out of 10, Excellent, (1,005 reviews)
"Angel at the front desk was very helpful and courteous!"
United States
Oscar
The price is 3.103.046 ₫
3.668.079 ₫ total
includes taxes & fees
31 Jul - 1 Aug
Courtyard by Marriott San Antonio Six Flags at The Rim
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Medical Center District

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Lobby
Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
9.2
Wonderful
1,372 reviews
View
Lobby lounge
Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
9.0
Wonderful
1,018 reviews
View
Lobby
San Antonio Marriott Northwest Medical Center
3.5 star property
8.6
Excellent
1,097 reviews
View
Bar (on property)
Courtyard by Marriott Medical Center San Antonio
3.0 star property
8.8
Excellent
1,008 reviews
View
Free daily buffet breakfast
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
8.4
Very good
3,450 reviews
View

Where to stay in Medical Center District

Find the best Medical Center District areas for the activities you enjoy most.

Downtown San Antonio

A scenic riverfront great entertainment and top sights from San Antonio River to Alamodome – discover Downtown San Antonio, a destination also famous for its historic sites.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Uptown

If you're spending some time in Uptown, San Antonio Zoo and Aquarium and San Antonio River are top sights worth seeing.

La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

Stone Oak

Stone Oak is known for its abundant dining options, and you can plan a trip to Stone Ridge Market and Shops at Hardy Oak while you're in town.

Top Medical Center District Hotel Reviews

Frequently asked questions

What is Medical Center District like?
Travellers are sure to enjoy a stay in San Antonio's Medical Center District neighbourhood. Are you looking for Medical Center District travel tips? Make sure that you visit USAA Corporate Office Headquarters and The San Antonio Art Institute while you're in the neighbourhood.
How many hotels will I be able to find in Medical Center District?
Expedia has 132 hotels and other accommodation options in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to review the top deals on offer in Medical Center District.
What can I see and do in this San Antonio neighbourhood?
USAA Corporate Office Headquarters, The San Antonio Art Institute and Cinemark San Antonio 16 are just a few attractions to check out in Medical Center District. Wonderland of the Americas Mall and Regal Huebner Oaks are also worth a visit when you're out sightseeing in San Antonio.