What's it like in Midtown?

Midtown is a neighbourhood that travellers like for its riverfront, bars and libraries. Experience the best of Midtown with a visit to San Antonio Zoo and Aquarium and San Antonio River during your trip.

How many hotels will I be able to find in the Midtown area?

If you're searching for places to stay in San Antonio, Expedia has something to meet your needs with 225 Midtown hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in Midtown, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable provided that you cancel before the hotel’s cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to still cancel and be given a refund within 24 hours of booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the best deals in Midtown.

What are the top things to see and do in Midtown?

If you're looking for activities to do while you're in Midtown, look into Historic Brackenridge Golf Course and McFarlin Tennis Center. As you're discovering the neighbourhood, San Antonio Zoo and Aquarium and San Antonio River are some other places worth a visit. Alamodome, The Mix and Paper Tiger are just a few of the places to visit in and around Midtown. While you're out sightseeing in San Antonio, make sure that you visit other sights such as The Lonesome Rose or Sunken Garden Theater.

The Best Hotels in Midtown, San Antonio - 2026 Updated Prices

A riverside walkway with colorful umbrellas, a stone bridge, and a red sculpture.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Midtown hotels

O'Casey's Boutique Inn

Midtown

"O'Casey's was exactly the respite we needed during the 2nd leg of our trip. We enjoyed very good sleep, great breakfast choices, and beautiful walks. We were close enough to walk downtown to the River Walk, the Pearl Historic Brewing Co., and many great restaurants. The host and owner, Amanda, was so welcoming and gracious, making sure we had everything we needed. Thank you for the wonderful stay! We will be back!"

Thomas

4.796.237 ₫ total

includes taxes & fees

2 Jul - 3 Jul

Apartment (1 Bedroom) | Living area | 50-inch TV with digital channels

Remodeled Vintage Charm 1br/1ba Apt Close to DT

Midtown

Hilda

3.501.730 ₫ total

includes taxes & fees

15 Jul - 16 Jul

Remodeled Historic 1BR 1BA House Near Downtown

Midtown

4.803.550 ₫ total

includes taxes & fees

15 Jul - 16 Jul

Stunning 2br/1ba Historic Pad Few Steps Downtown

Midtown

"Location was close to downtown and met our needs. The house was clean and in good shape. Although, I think there were a few fire detectors missing. The dock was there and the detector was not. We didn't get to use the parking spot promised in the back due to concrete repair going on. But there was ample street parking. The fridge did not work when we arrived and the owner sent maintenance the next day to fix it. All in all, we had a great time."

Carrie

4.576.760 ₫ total

includes taxes & fees

7 Jul - 8 Jul

Best Western Plus Elmendorf Hotel / San Antonio Hotel

26.9 km from Midtown

David

1.720.148 ₫ total

includes taxes & fees

12 Jul - 13 Jul

Best Western Garden Inn

Uptown, 16.6 km from Midtown

2.357.078 ₫ total

includes taxes & fees

9 Jul - 10 Jul

Spark by Hilton San Antonio Dominion

28 km from Midtown

Steven

1.884.076 ₫ total

includes taxes & fees

29 Jul - 30 Jul

La Quinta Inn & Suites by Wyndham San Antonio Northwest

Far West Side, 20.2 km from Midtown

Catherine

2.741.486 ₫ total

includes taxes & fees

20 Jul - 21 Jul

Tru by Hilton San Antonio North

22 km from Midtown

Yuelin

2.341.178 ₫ total

includes taxes & fees

7 Jul - 8 Jul

Standard Studio, 1 King Bed, Refrigerator & Microwave | Premium bedding, laptop workspace, iron/ironing board, free WiFi

Extended Stay America Premier Suites - San Antonio - Schertz

25.3 km from Midtown

Joshua

2.613.899 ₫ total

includes taxes & fees

6 Jul - 7 Jul

Drury Inn & Suites Near La Cantera Parkway

La Cantera District, 18.2 km from Midtown

Juana

2.923.164 ₫ total

includes taxes & fees

12 Jul - 13 Jul

Hampton Inn & Suites Selma-San Antonio-Randolph AFB Texas

Live Oak, 20.7 km from Midtown

Tracy

2.532.174 ₫ total

includes taxes & fees

13 Jul - 14 Jul

Days Inn by Wyndham San Antonio Airport

Uptown, 7.5 km from Midtown

Alicia

1.630.104 ₫ total

includes taxes & fees

20 Jul - 21 Jul

Everhome Suites San Antonio Lackland near SeaWorld by Choice Hotels

Far West Side, 17 km from Midtown

Shon

3.381.450 ₫ total

includes taxes & fees

8 Jul - 9 Jul

Hotel Gibbs Downtown Riverwalk

Downtown San Antonio, 3.1 km from Midtown

John

2.301.272 ₫ total

includes taxes & fees

6 Jul - 7 Jul

InterContinental San Antonio Riverwalk by IHG

Downtown San Antonio, 2.7 km from Midtown

Edward

6.178.693 ₫ total

includes taxes & fees

5 Jul - 6 Jul

Spark By Hilton San Antonio Northwest near Six Flags

La Cantera District, 19.5 km from Midtown

Jamil

2.177.149 ₫ total

includes taxes & fees

12 Jul - 13 Jul

Courtyard by Marriott San Antonio Six Flags at The Rim

La Cantera District, 19.5 km from Midtown

Oscar

3.672.044 ₫ total

includes taxes & fees

31 Jul - 1 Aug

Best Western Medical Center North Inn & Suites Near Six Flags

Northwest Side, 13.9 km from Midtown

Cyndi

1.841.755 ₫ total

includes taxes & fees

7 Jul - 8 Jul

La Quinta Inn & Suites by Wyndham San Antonio N Stone Oak

Stone Oak, 17.7 km from Midtown

Azeez

2.458.742 ₫ total

includes taxes & fees

6 Jul - 7 Jul

View all properties

Where to stay in Midtown

Find the best Midtown areas for the activities you enjoy most.

A boat tour on a canal with a bridge in the background.

Downtown San Antonio

A scenic riverfront great entertainment and top sights from San Antonio River to Alamodome – discover Downtown San Antonio, a destination also famous for its historic sites.

See properties

A large, modern building with a blue and white color scheme, featuring a prominent circular window and a 'Welcome' sign.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

See properties

A large, abstract sculpture with a flowing design, set against a dramatic sky.

Uptown

If you're spending some time in Uptown, San Antonio Zoo and Aquarium and San Antonio River are top sights worth seeing.

See properties

A cityscape with a prominent tower, a large body of water, and a sunset.

Medical Center District

While visiting Medical Center District, you might make a stop by sights like USAA Corporate Office Headquarters and The San Antonio Art Institute.

See properties

A nighttime amusement park with roller coasters, a bridge, and a full moon.

La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

See properties

Top Midtown Hotel Reviews

Hotel Gibbs Downtown Riverwalk

10/10 Excellent

"Loved our stay here. Room was very nice. Clean and very unique. Would definitely stay here again. Close to Riverwalk and Alamo. Breakfast was great had a lot of options. Staff were very helpful. Parking was a breeze with the valet. Our vehicle took no time to get to us when we asked for it."