Search Hotels in Mission Bay, San Diego

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Top Trending Hotels Near Mission Bay, San Diego

The Dana on Mission Bay

3.5 star property
Mission Bay
9.0 out of 10, Wonderful, (3909)
"Staff was great, room was spotless, and map was easy to follow."
United States
Rosa
The price is 4.192.035 ₫
5.345.834 ₫ total
includes taxes & fees
12 Dec - 13 Dec
The Dana on Mission Bay

Hyatt Regency Mission Bay Spa and Marina

4.0 star property
Mission Bay
8.4 out of 10, Very good, (1578)
"Loved our stay "
United States
Jeremy
The price is 3.061.441 ₫
4.914.157 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Hyatt Regency Mission Bay Spa and Marina

San Diego Mission Bay Resort

4.0 star property
Mission Bay
8.4 out of 10, Very good, (1312)
"great stay! Food was great and my kids loved the pool and location"
United States
ANDREA
The price is 4.411.534 ₫
6.259.738 ₫ total
includes taxes & fees
14 Dec - 15 Dec
San Diego Mission Bay Resort

Paradise Point Resort & Spa

4.0 star property
Mission Bay
8.6 out of 10, Excellent, (2363)
"Amazing place!"
United States
Barak Ben
The price is 3.410.313 ₫
5.315.184 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Paradise Point Resort & Spa

Wyndham San Diego Bayside

4.0 star property
8 km from Mission Bay
8.4 out of 10, Very good, (6055)
"Always an amazing stay"
United States
Jana
The price is 3.563.770 ₫
4.896.713 ₫ total
includes taxes & fees
7 Dec - 8 Dec
Wyndham San Diego Bayside

Hard Rock Hotel San Diego

4.0 star property
Gaslamp Quarter, 9.7 km from Mission Bay
9.0 out of 10, Wonderful, (3145)
"Great stay"
United States
Laurence
The price is 6.264.167 ₫
8.471.658 ₫ total
includes taxes & fees
8 Dec - 9 Dec
Hard Rock Hotel San Diego

Best Western Plus Marina Gateway Hotel

3.5 star property
16.7 km from Mission Bay
9.2 out of 10, Wonderful, (3490)
"Clean, staff friendly, great place for a stay"
United States
Derrick
The price is 3.299.026 ₫
3.635.362 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Best Western Plus Marina Gateway Hotel

Palihotel San Diego Gaslamp Quarter

4.0 star property
Gaslamp Quarter, 9.1 km from Mission Bay
8.6 out of 10, Excellent, (2073)
"Room was spotless and location great. "
United States
James
The price is 2.768.325 ₫
3.209.735 ₫ total
includes taxes & fees
12 Dec - 13 Dec
Palihotel San Diego Gaslamp Quarter

Legacy Resort Hotel & Spa

4.0 star property
5.3 km from Mission Bay
9.2 out of 10, Wonderful, (2986)
"Friendly, staff was very helpful, great size rooms, and over all was an amazing stay"
United States
Naya
The price is 4.011.435 ₫
4.610.944 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Legacy Resort Hotel & Spa

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
9.3 km from Mission Bay
9.0 out of 10, Wonderful, (2684)
"Clean room, almost everything to walk to, recommended and will booked again. "
United States
Karla
The Horton Grand, Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

3.0 star property
Gaslamp Quarter, 9.6 km from Mission Bay
9.0 out of 10, Wonderful, (1247)
"Very nice clean room and amenities and staff was pleasant and we love the location. "
United States
Arnold
The price is 3.339.127 ₫
3.871.551 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

The Bristol Hotel San Diego

3.5 star property
8.7 km from Mission Bay
8.6 out of 10, Excellent, (1448)
"Great stay, clean room. Staff was very friendly as well. Would stay again. "
United States
Alexis
The price is 3.303.534 ₫
3.830.282 ₫ total
includes taxes & fees
18 Dec - 19 Dec
The Bristol Hotel San Diego

Gaslamp Plaza Suites

3.5 star property
Gaslamp Quarter, 9 km from Mission Bay
9.0 out of 10, Wonderful, (1016)
"Great room, clean, spacious and quiet. "
United States
Maria
The price is 2.926.959 ₫
3.329.415 ₫ total
includes taxes & fees
9 Dec - 10 Dec
Gaslamp Plaza Suites

The Sofia Hotel

3.5 star property
8.7 km from Mission Bay
8.4 out of 10, Very good, (1663)
"Excellent stay all-around!"
United States
Nalani
The Sofia Hotel

Staypineapple, Hotel Z, Gaslamp San Diego

3.0 star property
Gaslamp Quarter, 9.4 km from Mission Bay
9.4 out of 10, Exceptional, (1000)
"The room was immaculate, the staff were helpful and friendly and our stay was so wonderful. "
United States
Samantha Erin
The price is 2.749.869 ₫
3.950.284 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Staypineapple, Hotel Z, Gaslamp San Diego

Marriott Marquis San Diego Marina

4.0 star property
9.2 km from Mission Bay
9.2 out of 10, Wonderful, (1942)
"Great hotel"
United States
Farzana
The price is 4.192.035 ₫
6.246.990 ₫ total
includes taxes & fees
12 Dec - 13 Dec
Marriott Marquis San Diego Marina

Days Inn by Wyndham San Diego Hotel Circle

3.0 star property
5.5 km from Mission Bay
8.0 out of 10, Very good, (2432)
"The room was excellent and the front desk staff very professional."
United States
Nelson
The price is 2.330.666 ₫
2.678.984 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Days Inn by Wyndham San Diego Hotel Circle

The DEXTRO Little Italy, BW Premier Collection

3.0 star property
8.2 km from Mission Bay
8.8 out of 10, Excellent, (702)
"Great staff, great location, great value. "
United States
Juan
The price is 2.404.853 ₫
2.788.306 ₫ total
includes taxes & fees
24 Dec - 25 Dec
The DEXTRO Little Italy, BW Premier Collection

Kings Inn San Diego

2.5 star property
4.9 km from Mission Bay
8.8 out of 10, Excellent, (3594)
"Spotless room, great environment and amazing food at Waffle Spot!"
United States
Eric
The price is 2.145.777 ₫
2.462.278 ₫ total
includes taxes & fees
8 Dec - 9 Dec
Kings Inn San Diego

Bay Club Hotel & Marina

3.5 star property
6.8 km from Mission Bay
9.2 out of 10, Wonderful, (3175)
"The staff is friendly and the hotel is perfect!"
United States
Mark
The price is 2.919.048 ₫
3.355.300 ₫ total
includes taxes & fees
8 Dec - 9 Dec
Bay Club Hotel & Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mission Bay

Find the best Mission Bay areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Lyceum Theatre – discover Gaslamp Quarter, a destination also famous for its shopping.

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Crystal Pier while you're exploring the area.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Dog Beach.

Top Mission Bay Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

What is Mission Bay like?
You'll be sure to have fun exploring San Diego's Mission Bay neighbourhood. Looking for sights you might find in a travel guide about Mission Bay? Consider a visit to Mission Bay while you're in the neighbourhood.
How many hotels should I expect to find in the Mission Bay area?
If you're searching for places to stay in San Diego, Expedia has something to meet your needs with 46 Mission Bay hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Mission Bay, will I receive a refund?
Yes, you'll find most room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to view top deals in Mission Bay.
What is there to do around this San Diego neighbourhood?
Enjoy a stroll along the shore at Mission and Pacific Beaches, Ski Beach and Crown Point Shores while you're in Mission Bay. You could also plan a visit to Mission Bay or Mission Bay Golf Course while you're in the neighbourhood. Hotel Circle, North Cove Beach and Bahia Point Beach are just a few of the places to visit in and around Mission Bay. When you're sightseeing in San Diego, Bay City Brewing Co. and Sail Bay are also worth a stop.