New Madrid Holidays
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Top hotels in New Madrid
Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
The price is 2.509.662 ₫ per night from 21 Dec to 22 Dec
2.509.662 ₫
2.841.565 ₫ total
21 Dec - 22 Dec
includes taxes & fees
8.8/10 Excellent! (439 reviews)
Exactly what I’ve come to expect from a Hampton.
Reviewed on 5 Dec 2025
Fairfield Inn & Suites by Marriott Sikeston
1239 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
The price is 2.662.562 ₫ per night from 18 Dec to 19 Dec
2.662.562 ₫
3.014.686 ₫ total
18 Dec - 19 Dec
includes taxes & fees
9.2/10 Wonderful! (40 reviews)
Staff
Reviewed on 8 Dec 2025
New Orleans Inn Portageville
600 US-61 Portageville MO
Fully refundableReserve now, pay when you stay
8/10 Very Good! (724 reviews)
Clean, comfortable, quiet and affordable. Would recommend this place to anyone passing through Portageville.
Reviewed on 3 Dec 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
New Madrid Historical Museum
You can study the exhibits at New Madrid Historical Museum, a museum with a storied past, during your travels to New Madrid. Amble around the area's parks or experience its museums.
River Ridge Winery
You can enjoy a tasting or tour at River Ridge Winery during your travels to New Madrid. Amble around the area's parks or experience its museums.
Hunter-Dawson State Historic Site
You can browse the exhibits at Hunter-Dawson State Historic Site, a museum with a story of its own, during your trip to New Madrid. Amble around the area's parks or experience its museums.
