New Madrid Holidays
Book a Hotel + Flight or Car together to unlock savings
Top hotels in New Madrid
Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
The price is 2.509.662 ₫ per night from 30 Nov to 1 Dec
2.509.662 ₫
2.841.564 ₫ total
30 Nov - 1 Dec
includes taxes & fees
8.8/10 Excellent! (429 reviews)
Modern up to date facilities
Reviewed on 23 Nov 2025
Fairfield Inn & Suites by Marriott Sikeston
1239 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
The price is 2.662.562 ₫ per night from 30 Nov to 1 Dec
2.662.562 ₫
3.014.686 ₫ total
30 Nov - 1 Dec
includes taxes & fees
9.2/10 Wonderful! (37 reviews)
Extremely clean, and it looks to be updated in the more recent years. Large workout room that looks into the pool. Hot and tasty breakfast.
Reviewed on 16 Nov 2025
New Orleans Inn Portageville
600 US-61 Portageville MO
Fully refundableReserve now, pay when you stay
8/10 Very Good! (723 reviews)
Good
Reviewed on 21 Nov 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
New Madrid Historical Museum
You can study the exhibits at New Madrid Historical Museum, a museum with a storied past, during your travels to New Madrid. Amble around the area's parks or experience its museums.
River Ridge Winery
You can enjoy a tasting or tour at River Ridge Winery during your travels to New Madrid. Amble around the area's parks or experience its museums.
Hunter-Dawson State Historic Site
You can browse the exhibits at Hunter-Dawson State Historic Site, a museum with a story of its own, during your trip to New Madrid. Amble around the area's parks or experience its museums.
