Find hotels in O Brien, FL from 1.136.002 ₫

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Our top choices for O Brien hotels

Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center
2.0 star property
Lake City
8.2 out of 10, Very good, (100 reviews)
"Great staff , friendly, accommodating "
United States
Lourdes
The price is 1.820.124 ₫
2.047.640 ₫ total
includes taxes & fees
20 Jan - 21 Jan
Motel 6 – Lake City, Fl – Medical Center

Econo Lodge Live Oak

Econo Lodge Live Oak
2.0 star property
Live Oak
7.0 out of 10, Good, (278 reviews)
"Clean room with plenty of towels and soaps. "
United States
Melissa
The price is 1.719.502 ₫
1.891.453 ₫ total
includes taxes & fees
18 Feb - 19 Feb
Econo Lodge Live Oak

Quality Inn & Suites Live Oak I-10 Exit 283

Quality Inn & Suites Live Oak I-10 Exit 283
2.5 star property
Live Oak
7.0 out of 10, Good, (525 reviews)
"Clean spacious rooms, friendly staff, convenient location "
United States
Jerry
The price is 2.386.023 ₫
2.624.626 ₫ total
includes taxes & fees
19 Feb - 20 Feb
Quality Inn & Suites Live Oak I-10 Exit 283

Royal Inn

Royal Inn
2.0 star property
Live Oak
6.2 out of 10, (46 reviews)
"Good for the price "
United States
Jaiden
Royal Inn

Holiday Inn Express & Suites Live Oak by IHG

Holiday Inn Express & Suites Live Oak by IHG
2.5 star property
Live Oak
8.4 out of 10, Very good, (790 reviews)
"This hotel is super convenient to I 10, road noise was no problem. I had a very quiet night on a comfortable bed. The cinnamon rolls on the breakfast bar are yummy! Also, check in was much faster than other hotels I’ve stayed in recently."
United States
Nancy
The price is 2.813.731 ₫
3.095.104 ₫ total
includes taxes & fees
25 Jan - 26 Jan
Holiday Inn Express & Suites Live Oak by IHG

Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee
2.5 star property
Live Oak
7.2 out of 10, Good, (628 reviews)
"Clean rooms, very friendly staff"
United States
Kristin L
The price is 1.711.884 ₫
1.883.072 ₫ total
includes taxes & fees
25 Jan - 26 Jan
Quality Inn White Springs Suwanee

High Springs Country Inn

High Springs Country Inn
2.0 star property
High Springs
8.4 out of 10, Very good, (18 reviews)
"Great remodel of a retro motel."
United States
Kathleen
The price is 1.655.136 ₫
1.862.029 ₫ total
includes taxes & fees
22 Jan - 23 Jan
High Springs Country Inn

BlueGem Motel

BlueGem Motel
2.0 star property
High Springs
9.2 out of 10, Wonderful, (401 reviews)
"Beautiful room, very clean and the bed was incredibly soft and comfortable to sleep in! "
United States
Julians
The price is 2.344.776 ₫
2.637.873 ₫ total
includes taxes & fees
21 Jan - 22 Jan
BlueGem Motel

Royal Inn

Royal Inn
2.0 star property
Alachua
7.2 out of 10, Good, (192 reviews)
"Good value and close to highway. "
United States
Ross
The price is 4.705.315 ₫
5.293.808 ₫ total
includes taxes & fees
1 Feb - 2 Feb
Royal Inn

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
2.0 star property
High Springs
10.0 out of 10, Exceptional, (166 reviews)
"We had such a great time, the cabin was nice and clean and had everything you might need. We loved the little detail of the handwritten postcard and map! The fireplace area was so nice too, perfect for a little getaway! "
United States
Ellie
The price is 2.434.101 ₫
4.989.448 ₫ total
includes taxes & fees
28 Jan - 29 Jan
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
2.5 star property
Alachua
9.4 out of 10, Exceptional, (480 reviews)
"Good overnight experience on a car trip. Nice staff."
United States
Luis
The price is 2.735.966 ₫
3.077.962 ₫ total
includes taxes & fees
1 Feb - 2 Feb
Hampton Inn & Suites Alachua I-75

Americas Best Value Inn Alachua

Americas Best Value Inn Alachua
2.0 star property
Alachua
4.8 out of 10, (601 reviews)
"Couldn’t check in "
United States
jeffrey
The price is 1.248.182 ₫
1.404.204 ₫ total
includes taxes & fees
20 Jan - 21 Jan
Americas Best Value Inn Alachua

Cindys Motel

Cindys Motel
2.5 star property
Mayo
8.8 out of 10, Excellent, (129 reviews)
"Nice place"
Australia
Marie
Cindys Motel

Suwannee River Rendezvous

Suwannee River Rendezvous
2.5 star property
Mayo
8.6 out of 10, Excellent, (21 reviews)
"Awesome place to stay, beautiful location and great accommodations. Friendly staff and lots to do!"
United States
Lauren
The price is 709.344 ₫
1.136.002 ₫ total
includes taxes & fees
20 Jan - 21 Jan
Suwannee River Rendezvous

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
Alachua
9.4 out of 10, Exceptional, (1,009 reviews)
"Great stay. Good breakfast. "
United States
Bob
The price is 3.021.280 ₫
3.398.941 ₫ total
includes taxes & fees
22 Jan - 23 Jan
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Comfort Suites Lake City

Comfort Suites Lake City
2.5 star property
Lake City
9.6 out of 10, Exceptional, (1,000 reviews)
"Clean room, great breakfast and staff super friendly "
United States
Gary
The price is 2.837.113 ₫
3.191.753 ₫ total
includes taxes & fees
25 Jan - 26 Jan
Comfort Suites Lake City

Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,004 reviews)
"Room was spotless and great atmosphere "
United States
Melissa
The price is 3.257.728 ₫
3.664.943 ₫ total
includes taxes & fees
21 Jan - 22 Jan
Hampton Inn & Suites Lake City

Holiday Inn & Suites Lake City by IHG

Holiday Inn & Suites Lake City by IHG
3.0 star property
Lake City
8.6 out of 10, Excellent, (1,003 reviews)
"Great place"
United States
John
The price is 2.285.664 ₫
2.571.503 ₫ total
includes taxes & fees
25 Jan - 26 Jan
Holiday Inn & Suites Lake City by IHG

Home2 Suites by Hilton Lake City

Home2 Suites by Hilton Lake City
3.0 star property
Lake City
9.4 out of 10, Exceptional, (751 reviews)
"This is an excellent hotel while you roadtrip:)"
United States
Desiree Moreno
The price is 3.214.642 ₫
3.616.604 ₫ total
includes taxes & fees
25 Jan - 26 Jan
Home2 Suites by Hilton Lake City

Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City
2.5 star property
Lake City
9.0 out of 10, Wonderful, (185 reviews)
"Friendly staff, convenient location, clean rooms, excellent breakfast"
United States
Keith
The price is 2.434.101 ₫
2.738.363 ₫ total
includes taxes & fees
25 Jan - 26 Jan
Fairfield Inn & Suites Lake City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida

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Frequently asked questions

What's the seasonal weather in O Brien?
The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 14°C. Average annual precipitation for O Brien is 1278 mm.