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Check prices for these dates

Tonight
11 Dec - 12 Dec
Tomorrow
12 Dec - 13 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

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Our top choices for Prague 21 hotels

Restaurant
Dvůr Hoffmeister

Dvůr Hoffmeister

Dvůr Hoffmeister
3.0 star property
31.9 km from Prague 21
9.6 out of 10, Exceptional, (89)
"The lovely bathroom and jet tub Place was pretty nice and away from the busy tourist areas "
United States
Natisha
Dvůr Hoffmeister
Exterior
a&o Prague Rhea

a&o Prague Rhea

a&o Prague Rhea
3.0 star property
12.4 km from Prague 21
8.0 out of 10, Very good, (606)
"Great stay, love this hostel "
United States
Timothy
The price is 752.982 ₫
969.777 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
a&o Prague Rhea
Daily full breakfast (CZK 475 per person)
Courtyard by Marriott Prague Airport

Courtyard by Marriott Prague Airport

Courtyard by Marriott Prague Airport
4.0 star property
29 km from Prague 21
9.2 out of 10, Wonderful, (1000)
"Very convenient and comfortable stay by the airport. "
United States
Stephanie
The price is 3.062.956 ₫
3.556.949 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Courtyard by Marriott Prague Airport
Spa reception
Majestic Plaza Hotel Prague

Majestic Plaza Hotel Prague

Majestic Plaza Hotel Prague
4.5 star property
Nové Město, 17.7 km from Prague 21
9.0 out of 10, Wonderful, (1086)
"Great hotel,clean rooms ,delicious breakfast.Close to many amenities "
United States
Ana
The price is 1.779.537 ₫
2.119.413 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Majestic Plaza Hotel Prague
Premium bedding, in-room safe, soundproofing, iron/ironing board
SKY Hotel Prague

SKY Hotel Prague

SKY Hotel Prague
3.5 star property
26.1 km from Prague 21
8.6 out of 10, Excellent, (576)
"Very clean, comfortable. Well-lit with good locations of lights. The bed was comfortable and linens were great. There is a nice coffee machine in the lobby that makes espresso. Nice gentleman helped us with accessing our room. I really recommend this hotel and we enjoyed the visit, staying two extra nights."
United States
Lisa
SKY Hotel Prague
Front of property
Grandium Hotel Prague

Grandium Hotel Prague

Grandium Hotel Prague
5.0 star property
Nové Město, 17.3 km from Prague 21
9.2 out of 10, Wonderful, (1110)
"Great rooms, friendly staff, wonderful breakfast"
United States
Toni
The price is 2.326.999 ₫
2.732.668 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Grandium Hotel Prague
Lobby
Michelangelo Grand Hotel Prague

Michelangelo Grand Hotel Prague

Michelangelo Grand Hotel Prague
5.0 star property
Nové Město, 18 km from Prague 21
9.4 out of 10, Exceptional, (3110)
"Great location, lovely hotel "
United Kingdom
Sally Louise
Michelangelo Grand Hotel Prague
Front of property
Charles Bridge Palace

Charles Bridge Palace

Charles Bridge Palace
4.0 star property
Stare Mesto, 18.4 km from Prague 21
9.2 out of 10, Wonderful, (1010)
"We enjoyed our stay! The staff were wonderful and the location was amazing."
Australia
Robert
Charles Bridge Palace
Local cuisine
Cosmopolitan Hotel Prague

Cosmopolitan Hotel Prague

Cosmopolitan Hotel Prague
5.0 star property
Petrská čtvrť, 17.2 km from Prague 21
9.6 out of 10, Exceptional, (1069)
"Great location and fantastic hotel "
United Kingdom
David
The price is 3.199.740 ₫
3.710.040 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Cosmopolitan Hotel Prague
Lobby
Hilton Prague

Hilton Prague

Hilton Prague
5.0 star property
16.7 km from Prague 21
8.4 out of 10, Very good, (1001)
"Very excellent Hotel would recommend to anyone!"
Canada
Damien
The price is 1.746.423 ₫
2.081.103 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Hilton Prague
Meeting facility
Holiday Inn Prague Airport by IHG

Holiday Inn Prague Airport by IHG

Holiday Inn Prague Airport by IHG
4.0 star property
28.4 km from Prague 21
8.8 out of 10, Excellent, (1002)
"The room was clean and breakfast was good "
United States
Kest
The price is 2.545.012 ₫
2.976.744 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Holiday Inn Prague Airport by IHG
Terrace/patio
Vienna House by Wyndham Diplomat Prague

Vienna House by Wyndham Diplomat Prague

Vienna House by Wyndham Diplomat Prague
4.5 star property
20.4 km from Prague 21
9.2 out of 10, Wonderful, (564)
"Great hotel. We have stayed here often when we are in Prague. "
United States
jim
The price is 2.483.600 ₫
2.908.070 ₫ total
includes taxes & fees
9 Jan - 10 Jan 2026
Vienna House by Wyndham Diplomat Prague
Front of property – evening/night
Art Nouveau Palace Hotel

Art Nouveau Palace Hotel

Art Nouveau Palace Hotel
5.0 star property
Nové Město, 17.5 km from Prague 21
9.4 out of 10, Exceptional, (1005)
"Excellent hotel with friendly staff, great decor and convenient. Highly recommend this hotel."
United Kingdom
John
The price is 2.610.498 ₫
3.051.133 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Art Nouveau Palace Hotel
Exterior
Mosaic House Design Hotel

Mosaic House Design Hotel

Mosaic House Design Hotel
4.0 star property
Nové Město, 18.2 km from Prague 21
9.8 out of 10, Exceptional, (713)
"Friendly and helpful staff on arrival and when asking for recommendations. Great room with everything needed for a comfortable stay. Spacious bathroom. Nice outside space on the balcony. "
United Kingdom
Andrew
The price is 2.260.121 ₫
2.717.766 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
Mosaic House Design Hotel
Breakfast, lunch and dinner served
Grand Majestic Hotel Prague

Grand Majestic Hotel Prague

Grand Majestic Hotel Prague
4.0 star property
Petrská čtvrť, 17.4 km from Prague 21
9.2 out of 10, Wonderful, (1180)
"Clean rooms, quiet, great location"
Canada
Debra
The price is 2.463.974 ₫
2.885.982 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
Grand Majestic Hotel Prague
Front of property
Hermitage Hotel Prague

Hermitage Hotel Prague

Hermitage Hotel Prague
4.5 star property
18.2 km from Prague 21
9.4 out of 10, Exceptional, (1000)
"Location is good; the breakfast is excellent; front desk personnel is super nice and professional"
United States
Wenzhou
The price is 2.185.568 ₫
2.574.275 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Hermitage Hotel Prague
Free daily buffet breakfast
Archibald At the Charles Bridge

Archibald At the Charles Bridge

Archibald At the Charles Bridge
3.0 star property
Mala Strana, 18.9 km from Prague 21
9.6 out of 10, Exceptional, (1043)
"Great hotel, very clean, helpful staff "
United Kingdom
John
The price is 2.436.597 ₫
2.855.320 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Archibald At the Charles Bridge
Property entrance
Unitas Hotel

Unitas Hotel

Unitas Hotel
4.0 star property
Stare Mesto, 18.3 km from Prague 21
9.8 out of 10, Exceptional, (1002)
"Clean room Staff great Breakfast super Near tourist area"
United Kingdom
Joby Varghese
The price is 6.775.929 ₫
7.715.372 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Unitas Hotel
Exclusive Suite, Terrace | Terrace/patio
Grand Hotel Bohemia

Grand Hotel Bohemia

Grand Hotel Bohemia
5.0 star property
Stare Mesto, 17.6 km from Prague 21
9.6 out of 10, Exceptional, (1001)
"The location was fantastic. Breakfast was amazing. Everyone working at the hotel was pleasant and professional!"
United States
Richard
The price is 3.728.676 ₫
4.299.995 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
Grand Hotel Bohemia
Exterior
Mama Shelter Prague

Mama Shelter Prague

Mama Shelter Prague
4.0 star property
Holesovice, 17.4 km from Prague 21
9.4 out of 10, Exceptional, (1006)
"Very nice hotel, well located and right across of public transportation "
United States
Humberto
The price is 1.954.753 ₫
2.314.428 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Mama Shelter Prague
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Prague 21

Find the best Prague 21 areas for the activities you enjoy most.
Charles Bridge which includes a city, a river or creek and heritage elements

Prague City Center

Museum of Medieval Torture and Old Town Bridge Tower are top sights in Prague City Center, and you should be sure to explore the acclaimed art galleries. Hop aboard the metro at Karlovy Lázně Stop or Staroměstská Stop to see more sights in the area.

Czech Republic featuring a city, heritage architecture and a square or plaza

Stare Mesto

Gourmet restaurants interesting history and top sights from Havelska Market to Klementinum-Prague National Library – discover Stare Mesto, a destination also famous for its shopping.

Nove Mesto which includes railway items, a city and heritage elements

Nové Město

Gourmet restaurants interesting history and top sights from Charles Square to New Town Hall – discover Nové Město, a destination also famous for its shopping.

Prague which includes a city

Prague 1

Known for its popular shops and acclaimed art galleries, there's plenty to explore in Prague 1. Check out top attractions like Old Town Square and Royal Route, and jump on the metro at Staromestska Station or Staroměstská Stop to see more of the city.

Nove Mesto showing a bay or harbour

Prague 2

Known for its ample dining options and fascinating museums, there's plenty to explore in Prague 2. You can visit top attractions like Peace Square and New Town Hall, and jump on the metro at Náměstí Míru Stop or Namesti Miru Station to see more of the city.

Top Prague 21 Hotel Reviews

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Frequently asked questions

What's it like in Prague 21?
Travellers will be sure to enjoy their time in Prague's Prague 21 neighbourhood.
If I need to cancel my hotel reservation in Prague 21, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and be given a refund within 24 hours of booking. Enter your dates, click on "Search", then filter by "fully refundable" to review the best deals available in Prague 21.
What can I see and do in this Prague neighbourhood?
Some places to visit in the Prague area include House of the Black Madonna, Na Prikope and Powder Tower so get out of the neighbourhood to explore more of the city. While you're out sightseeing, Municipal House Hall and Museum of Communism are a couple of sights to visit in the city.
How can I get around Prague 21 and the greater Prague area?
If you're considering venturing out of town, train travel is a great option. Prague-Klanovice Station is the closest train station, but Prague-Běchovice střed Station and Prague-Bechovice Station are also close by.