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Residence Inn Durham McPherson/Duke University Medical Cntr

3.0 star property
Hotel with free breakfast, 5-minute walk to Duke University

Choose dates to view prices

Residence Inn Durham McPherson/Duke University Medical Center offers a refreshed retreat with practical comforts. Enjoy a to-go breakfast, relax by the lobby fireplace, and request complimentary grocery shopping. WiFi in all rooms and an area shuttle make attractions accessible.

Reviews

9.2 out of 10
Wonderful

Popular amenities

  • Bar
  • Kitchen
  • Parking available
  • Housekeeping
The current price is 3.450.030 ₫
3.915.784 ₫ total
includes taxes & fees
23 Nov - 24 Nov

Room options

Available filters for rooms
Showing 10 of 10 rooms

View all photos for Suite, 1 Bedroom

32-inch Smart TV with cable channels, TV, Netflix

Suite, 1 Bedroom

9.2 out of 10
Wonderful
(5 reviews)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
Separate sitting area
Air-conditioning
Dining table
Blackout drapes/curtains
Sofa bed
Hair dryer
  • 44 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed

View all photos for Studio, 1 King Bed with Sofa bed, Non Smoking

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 King Bed with Sofa bed, Non Smoking

8.8 out of 10
Excellent
(32 reviews)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
Separate sitting area
Air-conditioning
Dining table
Blackout drapes/curtains
Sofa bed
Hair dryer
  • 45 sq m
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio, 1 Queen Bed with Sofa bed, Non Smoking

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 Queen Bed with Sofa bed, Non Smoking

9.6 out of 10
Exceptional
(14 reviews)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
Separate sitting area
Air-conditioning
Dining table
Blackout drapes/curtains
Sofa bed
Hair dryer
  • 39 sq m
  • Sleeps 3
  • 1 Queen Bed and 1 Double Sofa Bed

View all photos for Suite, 1 Bedroom, Non Smoking (Hearing Accessible)

1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 Bedroom, Non Smoking (Hearing Accessible)

8.8 out of 10
Excellent
(3 reviews)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
Separate sitting area
Air-conditioning
Dining table
Blackout drapes/curtains
Hair dryer
Shower/tub combination
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed

View all photos for Studio, 1 King Bed with Sofa bed (Mobility/Hearing Accessible, Tub)

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 King Bed with Sofa bed (Mobility/Hearing Accessible, Tub)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
Separate sitting area
Air-conditioning
Dining table
Blackout drapes/curtains
Hair dryer
Private bathroom
  • 44 sq m
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
Separate sitting area
Air-conditioning
Dining table
Blackout drapes/curtains
Sofa bed
Hair dryer
  • 45 sq m
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio, 1 King Bed with Sofa bed (Hearing Accessible)

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 King Bed with Sofa bed (Hearing Accessible)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
Separate sitting area
Air-conditioning
Dining table
Blackout drapes/curtains
Sofa bed
Hair dryer
  • 45 sq m
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio, 1 Queen Bed with Sofa bed (Hearing Accessible)

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 Queen Bed with Sofa bed (Hearing Accessible)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
Separate sitting area
Air-conditioning
Dining table
Blackout drapes/curtains
Sofa bed
Hair dryer
  • 40 sq m
  • Sleeps 3
  • 1 Queen Bed and 1 Double Sofa Bed

View all photos for Suite, Multiple Beds, Non Smoking (Mobility Accessible, Tub)

Suite, Multiple Beds, Non Smoking (Mobility Accessible, Tub) | 1 bedroom, in-room safe, desk, laptop workspace

Suite, Multiple Beds, Non Smoking (Mobility Accessible, Tub)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
Separate sitting area
Air-conditioning
Dining table
Blackout drapes/curtains
Hair dryer
Shower/tub combination
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed

View all photos for Suite, 1 Bedroom, Non Smoking (Mobility Accessible, Roll-in Shower)

1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 Bedroom, Non Smoking (Mobility Accessible, Roll-in Shower)

10.0 out of 10
Exceptional
(1 review)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
Separate sitting area
Air-conditioning
Dining table
Blackout drapes/curtains
Hair dryer
Shower/tub combination
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed

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About the area

Map
1108 West Main Street, Durham, NC, 27701

What's nearby

  • Duke University - 3 min walk - 0.3 km
  • Durham Bulls Athletic Park - 16 min walk - 1.4 km
  • Durham Performing Arts Center - 17 min walk - 1.4 km
  • Duke University Hospital - 2 min drive - 2.8 km
  • Cameron Indoor Stadium - 6 min drive - 4.1 km

Getting around

  • Durham Station - 8 min walk
  • Raleigh-Durham International Airport (RDU) - 19 min drive

Restaurants

  • ‪The Can Opener - ‬7 min walk
  • ‪Ramblers - ‬7 min walk
  • ‪Fonda Lupita - ‬3 min walk
  • ‪Emmy Squared - ‬5 min walk
  • ‪The Federal - ‬3 min walk

About this property

Residence Inn Durham McPherson/Duke University Medical Cntr

Hotel remodelled in 2024 and located near Duke University
Consider a stay at Residence Inn Durham McPherson/Duke University Medical Cntr and take advantage of free on-the-go breakfast, a free food/drink shopping service and a terrace. In addition to dry cleaning/laundry services and a fireplace in reception, guests can connect to free in-room WiFi.
Other perks include:
  • A free local area shuttle, self-parking (surcharge) and express check-out
  • Express check-in, wedding services and smoke-free property
  • Coffee/tea in reception, luggage storage and concierge services
  • Guest reviews say great things about the helpful staff
Room features
All 147 rooms include comforts such as laptop-friendly workspaces and air conditioning, in addition to thoughtful touches such as free WiFi and desk chairs.
More conveniences in all rooms include:
  • Recycling and LED light bulbs
  • Shower/bath combinations, free toiletries and hairdryers
  • 32-inch Smart TVs with Netflix and premium channels
  • Wardrobes/cupboards, separate sitting areas and kitchens

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AC Hotel Durham

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  • Free WiFi
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  • Air conditioning
9.2 out of 10, Wonderful, 594 reviews
The price is 3.108.527 ₫
3.528.178 ₫ total
includes taxes & fees
23 Nov - 24 Nov
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Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transport

  • Free area shuttle
  • Parking on site (USD 15 per day)
  • Wheelchair-accessible parking available

Food and drink

  • Free on-the-go breakfast available daily 7:00 AM to 9:00 AM
  • A bar/lounge
  • Coffee and tea in common areas

Things to do

  • 24-hour gym

Family friendly

  • Dining table
  • Free area shuttle
  • Grocery/convenience store
  • In-room full-sized refrigerator/freezer
  • In-room kitchen
  • In-room microwave
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Grocery/convenience store
  • Laundry facilities
  • Luggage storage
  • Safe at front desk

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Free grocery shopping service
  • Housekeeping (daily)
  • Wedding services

Business services

  • 2,530 square feet of conference space
  • Business centre
  • Computer station

Outdoors

  • Terrace

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • 7 accessible parking spaces
  • Assistive listening devices in meeting rooms
  • Braille/raised signage
  • Hardwood flooring in room
  • Lever door handles
  • Lift (107 centimetre wide door)
  • Thin carpet in room
  • Visual alarms in hallways
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business centre
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to lift
  • Wheelchair-accessible registration desk (86 centimetre high)
  • Wheelchair-accessible restaurant

More

  • 5 floors
  • Banquet hall
  • Biodegradable coffee stirrers available
  • Built in 2015
  • Comprehensive recycling policy
  • Double-glazed windows
  • Fireplace in lobby
  • No plastic coffee stirrers
  • No plastic drinking straws
  • Renovated entire property - April 2024
  • Smoke-free property
  • Vegan dining options
  • Vegetarian breakfast available
  • Vegetarian dining options

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Free toiletries
  • Hair dryer
  • Shower/bathtub combination
  • Towels provided

Entertainment

  • 32-inch smart TV with premium cable channels
  • Netflix
  • Pay films

Food and drink

  • Coffee/tea maker
  • Cookware, dishware, and utensils
  • Dining table
  • Dishwasher
  • Full-sized refrigerator/freezer
  • Hob
  • Kitchen
  • Microwave

More

  • Air conditioning (climate-controlled)
  • Desk
  • Desk chair
  • Energy-saving switches in guestrooms
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • LED lighting
  • Phone
  • Recycling
  • Safe
  • Separate sitting area
  • Water-efficient showers

Policies

Check-in

Check-in start time: 3 PM; check-in end time: midnight
Express check-in available
Minimum check-in age - 21

Check-out

Check-out before noon
Contactless check-out
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

Pets are allowed for an extra charge of USD 100.00 per pet (varies based on length of stay)
Service animals are welcome, and are exempt from fees
2 total (up to 45 kg per pet)
Restrictions apply; for more information contact the property on the number on the booking confirmation

Children and extra beds

Children are welcome
Rollaway/extra beds are not available.
Cots (infant beds) are not available

Payment types at the property

Important information

Optional extras

  • Self-parking fee: USD 15 per day
  • Pet fee: USD 100.00 per pet (varies based on length of stay)
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a carbon monoxide detector and a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott)

We should mention

Guests under 18 years old are not allowed in the fitness facility, and guests under 18 years old are only allowed in the swimming pool and fitness facility with adult supervision
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn Durham McPherson/Duke University Medical Cntr
Residence Inn McPherson/Duke University Medical Cntr
Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn McPherson/Duke University Medical Cntr

Frequently asked questions

Is Residence Inn Durham McPherson/Duke University Medical Cntr pet-friendly?

Yes, Residence Inn Durham McPherson/Duke University Medical Cntr allows pets (limit 2 total) with a maximum weight of up to 45 kg per pet. There's a fee of USD 100.00 per pet, per stay. Service animals are exempt from fees. Some restrictions may apply, so please contact the property for more details.

How much does it cost to stay at Residence Inn Durham McPherson/Duke University Medical Cntr?

As of 10 Nov 2025, prices found for a 1-night stay for 2 adults at Residence Inn Durham McPherson/Duke University Medical Cntr on 23 Nov 2025 start from 3.450.030 ₫, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

How much is parking at Residence Inn Durham McPherson/Duke University Medical Cntr?

Self-parking is available for USD 15 per day.

What time is check-in at Residence Inn Durham McPherson/Duke University Medical Cntr?

Check-in start time: 3 PM; check-in end time: midnight.

What time is check-out at Residence Inn Durham McPherson/Duke University Medical Cntr?

Checkout is at noon.

Where is Residence Inn Durham McPherson/Duke University Medical Cntr located?

Located in Downtown Durham, this hotel is within a 10-minute walk of Brightleaf Square and Duke University. Carolina Theatre and Durham Convention Center are also within 15 minutes. Durham Station is 8 minutes by foot.

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Reviews

Residence Inn Durham McPherson/Duke University Medical Cntr Reviews

9.2

Wonderful

9.4

Cleanliness

9.0

Location

9.4

Staff & service

9.0

Eco-friendliness

9.4

Property conditions & facilities
Rating 10 - Excellent. 311 out of 454 reviews
Rating 8 - Good. 103 out of 454 reviews
Rating 6 - Okay. 25 out of 454 reviews
Rating 4 - Poor. 6 out of 454 reviews
Rating 2 - Terrible. 9 out of 454 reviews

Reviews

10/10 Excellent

Lisa

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Hotel was great - very friendly staff.
Stayed 2 nights in Sep 2025

8/10 Good

James

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice hotel for the price. Good location. Big rooms. Quiet. Easy parking. Could be a little cleaner.
Stayed 2 nights in Oct 2025

8/10 Good

nicole

Liked: Cleanliness, staff & service, property conditions & facilities
Clean room. Lighting in bathroom needs to be better.
Stayed 1 night in Oct 2025

10/10 Excellent

LaMeesha

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I am thankful for the very hospitable staff that I encountered at the hotel. Everyone was smiling at the front desk every time I passed by.
Stayed 8 nights in Jun 2025

10/10 Excellent

Wendy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean, friendly, great location.
Stayed 1 night in Sep 2024

8/10 Good

Lourdes Dolores

Liked: Cleanliness, property conditions & facilities, room comfort

Wasteful shower design

The room was clean and comfortable and the gym was good. However, I gave the hotel 3 stars because the shower lets out so much water that it is actually wasting water. There's no door for the shower, so when you bathe, the water streams out of the shower and onto the bathroom floor. So much water streams out that I had to place the bathmat 12 inches away from the shower entrance so that it wouldn't get wet.
Stayed 10 nights in Jun 2025

10/10 Excellent

Jackson

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice clean room,good breakfast and great staff.
Stayed 4 nights in Nov 2022

6/10 Okay

Tian

Disliked: Staff & service, amenities
It smelled musky and like urine in our room and much of the facility just smelled like cleaning supplies. The wifi wasn’t great in the room. The location is decently close to Duke, but the immediate area is at a street intersection right by a gas station. There was plenty of parking for pay by mobile 15$.
Stayed 1 night in May 2025

10/10 Excellent

Karl

Liked: Cleanliness, staff & service, property conditions & facilities
The staff was very friendly and helpful!
Stayed 2 nights in May 2023

10/10 Excellent

Luis

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Extremely convenient for the purpose of my visit
Stayed 6 nights in Feb 2023

10/10 Excellent

Lalita

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Excellent

Loved how clean and big the room was.
Stayed 3 nights in Aug 2024

10/10 Excellent

eleshia A

Liked: Cleanliness, staff & service, property conditions & facilities
I like everything about the hotel
Stayed 1 night in Jul 2022

10/10 Excellent

Adrian

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Wonderful experience
Stayed 1 night in May 2024

8/10 Good

Deborah

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Amazing room, just skip the breakfast

The room itself is exceptional and perfect for a business stay or writing retreat, especially as the kitchen allows you to cook and stay focused on work without having to leave the room. Location is also great if you do want to explore restaurants and Duke. Only complaint is that their breakfast is mediocre at best.
Stayed 2 nights in Nov 2023

10/10 Excellent

Milton

Love it

The hotel was very nice. Customer service was good. The room was very clean and up to date.
Stayed 1 night in Jul 2022

10/10 Excellent

Christine

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Went to visit my daughter who is attending Duke. Great place to stay. Rooms were nice and clean. Very comfortable. The bar has signs for hours that were not accurate. A few night I was there I was told staff left “because it was slow”. This was at 7:00 at night. Seemed weird.
Stayed 6 nights in May 2024

8/10 Good

Deborah

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Property under construction so super noisy all day.
Stayed 3 nights in Apr 2024

2/10 Terrible

Michael

Disliked: Cleanliness, staff & service, property conditions & facilities, room comfort

Long drive to have my room given away.

After confirming my stay with the Residence Inn Durham by checking in online, then email exchange just hours before my arrival stating “I am on my way and would be there in 2hrs”- then the hotel acknowledging that check in… I got to the front desk at 6:10pm to find out I no longer had a room and was being re-booked at a different, lesser quality hotel 10 mins away. (After driving 9hrs to get there). Utterly ridiculous and I’ll never book a room with them again.
Stayed 1 night in Dec 2024

10/10 Excellent

Paul

Liked: Cleanliness, staff & service, amenities
Didn't like all the noisy remodeling going on.
Stayed 1 night in Apr 2024

6/10 Okay

Rafael

Liked: Cleanliness

"Refresh the room" failed

Good location and clean property. However, although requested to clean the room every other day, as they suggest, we have the room "refreshed" only one time in a 7-day stay
Stayed 6 nights in Aug 2023

8/10 Good

Eileen

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

FYI: parking costs

Nice place. Parking is NOT free despite Hotels.com saying it is. Desk clerk said Hotels.com has been contacted numerous times to delete reference to free parking. Website says parking costs $12/day. Pool is small but looks nice. Breakfast is nicer than most hotels provide.
Stayed 1 night in Oct 2022

10/10 Excellent

Jill

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I bought travel insurance for the first time ever from Expedia thinking it would cover any schedule changes I had. I let Expedia know well before the last day of my trip that I wanted to cancel my 3rd night and they said it was too late and I was charged anyway. Expedia is blaming the hotel but Expedia was where I paid for the hotel and the insurance so this has nothing to do with the hotel. Really disappointed with Expedia but the hotel was great.
Stayed 3 nights in Aug 2024

4/10 Poor

Kristen

Liked: Cleanliness, room comfort
Disliked: Staff & service, property conditions & facilities

Disappointing for the high price paid

Room wasn’t ready for 3pm checkin. Was given a queen room instead of the king we reserved so had to request the change to what was paid for. Toilet didn’t flush and all rooms were booked so stuck in a room without an operational toilet. Had to use the general facilities on the main hotel floor.
Stayed 1 night in Jun 2023

6/10 Okay

Melody

Liked: Cleanliness, property conditions & facilities
Disliked: Staff & service

Great location, clean room, disappointing service

I was visiting Durham to drop my daughter off for a 2-week camp. I thought Residence Inn would be perfect as we had been traveling for a few weeks and needed to prepare for her dropoff - laundry, ironing, strategic packing, etc. Sadly, things that should have been a convenience ended up a nuisance. At check-in we were told continental breakfast was served 7-10. We arrived at 9 and two employees were gathering the food and taking it to the kitchen. They told us breakfast was over. They were quite rude and more concerned with finishing their task quickly rather than accommodating a guest. When we mentioned the time we were given at check-in they dismissed us and said they had a job to do. Other interactions were small but added up to an overall frustrating experience. The fee for laundry was listed on a card in the room. We secured enough quarters only to get there and realize the actual cost was higher. Had to make another trip for quarters. Housekeeping knocked on our door at 8am despite having the 'do not disturb' hanger out. They came back again at 10. When we went to get our laundry around 10:30 we came back to the room and our key no longer worked requiring another trip to the front desk. Although check out wasn't until noon, housekeeping came back at 11:50 and told us we would be charged late checkout if we didn't leave. Again, all small interactions, but it left us feeling as if staff were more concerned with getting rid of us rather than our experience there.
Stayed 1 night in Jul 2023

10/10 Excellent

Anthony

Liked: Amenities
Yes
Stayed 4 nights in Sep 2025