Serra Mesa Travel Guide

San Diego

Aerial view of house in Serra Mesa City in San Diego, California, USA. Green Dry Valley and Villas

Popular places to visit


Top hotels in Serra Mesa

Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
The price is 6.231.437 ₫ per night from 5 Apr to 6 Apr
6.231.437 ₫
8.556.734 ₫ total
5 Apr - 6 Apr
includes taxes & fees
Stay at this beach resort in San Diego. Enjoy free Wi-Fi, 5 outdoor pools and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...
8.6/10 Excellent! (2,471 reviews)
They charge you 50.00 a night for parking

Reviewed on 26 Mar 2026

Paradise Point Resort & Spa
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
Fully refundable
The price is 2.157.755 ₫ per night from 1 Apr to 2 Apr
2.157.755 ₫
2.480.231 ₫ total
1 Apr - 2 Apr
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, free parking and 2 hot tubs. Our guests praise the pool and the restaurant in their reviews. ...
7.8/10 Good! (3,335 reviews)
Our second time staying at this location we loved it. Jennifer was helpful with nearby restaurant favorites as well as the on sire dining. We hope to return in the summer.

Reviewed on 26 Mar 2026

Best Western Seven Seas
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
The price is 4.826.954 ₫ per night from 2 Apr to 3 Apr
4.826.954 ₫
6.868.108 ₫ total
2 Apr - 3 Apr
includes taxes & fees
Stay at this hotel in San Diego. Enjoy free Wi-Fi, 2 restaurants and a nightclub. Our guests praise the helpful staff and the convenient parking in their reviews. ...
9/10 Wonderful! (3,435 reviews)
Dated. Very dated. Unfortunate.

Reviewed on 26 Mar 2026

Hard Rock Hotel San Diego
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
The price is 3.058.422 ₫ per night from 13 Apr to 14 Apr
3.058.422 ₫
3.515.503 ₫ total
13 Apr - 14 Apr
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Our guests praise the pool and the helpful staff in their ...
8.2/10 Very Good! (2,355 reviews)
Phenomenal

Reviewed on 26 Mar 2026

Handlery Hotel
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
The price is 3.784.395 ₫ per night from 29 Mar to 30 Mar
3.784.395 ₫
4.387.816 ₫ total
29 Mar - 30 Mar
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour fitness centre. Our guests praise the helpful staff ...
8.8/10 Excellent! (1,261 reviews)
The hotel is very nice and clean. The issues are parking is very limited. We had to park on the street. The area is has a large population of homeless. Normally Best Western has breakfast as part of the stay but you have to pay extra at this hotel.

Reviewed on 26 Mar 2026

The DEXTRO Little Italy, BW Premier Collection
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S San Diego CA
The price is 2.821.335 ₫ per night from 26 Apr to 27 Apr
2.821.335 ₫
3.242.983 ₫ total
26 Apr - 27 Apr
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, a fitness centre and parking (surcharge). Our guests praise the helpful staff and the clean ...
8/10 Very Good! (2,567 reviews)
Easy check in & out. Great parking. Super clean & comfy bed & great big bathroom

Reviewed on 26 Mar 2026

Days Inn by Wyndham San Diego Hotel Circle
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Serra Mesa

Modern apartment building complex in Mission Valley, San Diego

Linda Vista

When in Linda Vista and the surrounding area, you'll want to check out sights like Fashion Valley Mall or Mission Valley Mall and hop on the metro to see more of the city at Morena - Linda Vista Station or Tecolote Road Station.

Linda Vista
Closeup of the Adobe walls of the historic Mission De Alcala San Diego California

Mission Valley

4/5(36 area reviews)

Known for its stunning beaches and popular shops, there's plenty to explore in Mission Valley. Check out top attractions like Mission Valley Mall and Fashion Valley Mall, and jump on the metro at Hazard Center Station or Mission Valley Center Station to see more of the city.

Mission Valley
North Park sign at sunset, in San Diego, California

North Park

North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and San Diego Natural History Museum if you have time to explore the area.

North Park
San Diego Bay. Panoramic view from Cabrillo National Monument, California

Bay Park

5/5(1 area review)

If you're looking for beaches and seaside views, Bay Park might be a great stop. Notable sights like Clairemont Village Shopping Center are also worth visiting, and you might jump aboard the metro at Clairemont Drive Station or Balboa Avenue Transit Center Station to get around town.

Bay Park
Gossip Grill

Hillcrest

5/5(1 area review)

Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.

Hillcrest
I didn’t go in as I felt the outside was pretty great already. Good area of town for a self-guided walking tour.

Old Town San Diego

4/5(5 area reviews)

The abundant dining options and seaside views are top of the list for many visitors to Old Town San Diego. A stop by Old Town San Diego State Park or Whaley House Museum might round out your trip.

Old Town San Diego


Serra Mesa Travel Guide

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