Search Hotels in Serra Mesa, San Diego

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Our top choices for Serra Mesa hotels

Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG
3.5 star property
6.4 km from Serra Mesa
8.0 out of 10, Very good, (1,021 reviews)
"Clean room, nice property, perfect for our overnight stay. "
United States
Rocio
Crowne Plaza San Diego - Mission Valley by IHG

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
10.1 km from Serra Mesa
8.4 out of 10, Very good, (3,390 reviews)
"Beautiful resort! Clean, well decorated and sights are stunning - will stay again! "
Canada
Emily
The price is 4.451.967 ₫
6.276.483 ₫ total
includes taxes & fees
1 Apr - 2 Apr
Sheraton San Diego Resort

Valli Hi Motel

Valli Hi Motel
2.5 star property
28.3 km from Serra Mesa
8.4 out of 10, Very good, (1,001 reviews)
"The room was good for what i needed close to gas stations, mcdonalds supermarket so great location "
United States
Kasandra
Valli Hi Motel

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
28.8 km from Serra Mesa
9.2 out of 10, Wonderful, (1,791 reviews)
"Best vacation ever! Staff was super friendly and accommodating"
United States
Michelle
Sycuan Casino Resort

Ash&9th

Ash&9th
2.0 star property
9.4 km from Serra Mesa
8.2 out of 10, Very good, (450 reviews)
"Great location as we could walk to Balboa Park, zoo, port etc."
Australia
Jocelyn
The price is 2.063.048 ₫
2.346.717 ₫ total
includes taxes & fees
7 Apr - 8 Apr
Ash&9th

Bahia Resort Hotel

Bahia Resort Hotel
3.5 star property
Central Mission Beach, 10.7 km from Serra Mesa
8.6 out of 10, Excellent, (1,932 reviews)
"We stay here a few times a year normally and love the location. "
United States
Lindsay
The price is 6.377.640 ₫
8.791.706 ₫ total
includes taxes & fees
26 Apr - 27 Apr
Bahia Resort Hotel

El Cordova Hotel on Coronado Island

El Cordova Hotel on Coronado Island
3.5 star property
13.9 km from Serra Mesa
8.8 out of 10, Excellent, (1,002 reviews)
"Best hotel i have stayed"
United States
araceli
The price is 5.067.601 ₫
6.374.532 ₫ total
includes taxes & fees
26 Apr - 27 Apr
El Cordova Hotel on Coronado Island

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
9 km from Serra Mesa
7.4 out of 10, Good, (4,194 reviews)
"Nice friendly staff"
Canada
Wayne
The price is 3.058.422 ₫
3.515.473 ₫ total
includes taxes & fees
1 Apr - 2 Apr
Wyndham Garden San Diego Near SeaWorld

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
4.0 star property
10.8 km from Serra Mesa
9.2 out of 10, Wonderful, (2,063 reviews)
"Everything was great Food pool room view…"
United States
Lyudmila
The price is 4.821.684 ₫
6.840.798 ₫ total
includes taxes & fees
6 Apr - 7 Apr
Marriott Marquis San Diego Marina

GreenTree Inn San Diego Mission Bay

GreenTree Inn San Diego Mission Bay
2.5 star property
Pacific Beach, 7.3 km from Serra Mesa
8.0 out of 10, Very good, (1,989 reviews)
"Great stay"
United States
Lizeth
The price is 2.752.580 ₫
3.163.954 ₫ total
includes taxes & fees
9 Apr - 10 Apr
GreenTree Inn San Diego Mission Bay

California Suites Hotel

California Suites Hotel
2.0 star property
4.8 km from Serra Mesa
7.8 out of 10, Good, (2,417 reviews)
"Thoroughly enjoyed our stay. The rooms were nice, clean, and liked the internet connection. "
United States
Melissa
California Suites Hotel

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
9.9 km from Serra Mesa
8.4 out of 10, Very good, (6,068 reviews)
"Great rooms & location"
Canada
Priscilla
The price is 4.243.857 ₫
5.837.081 ₫ total
includes taxes & fees
2 Apr - 3 Apr
Wyndham San Diego Bayside

Heritage Inn San Diego

Heritage Inn San Diego
2.0 star property
9.1 km from Serra Mesa
7.4 out of 10, Good, (1,341 reviews)
"Great and easy way to check in and out!"
United States
Pedro
The price is 1.716.572 ₫
1.973.202 ₫ total
includes taxes & fees
6 Apr - 7 Apr
Heritage Inn San Diego

Bay Club Hotel & Marina

Bay Club Hotel & Marina
3.5 star property
12.6 km from Serra Mesa
9.2 out of 10, Wonderful, (3,507 reviews)
"Really nice hotel, and the location is beautiful. "
United States
Gloire
The price is 4.372.938 ₫
5.026.474 ₫ total
includes taxes & fees
2 Apr - 3 Apr
Bay Club Hotel & Marina

SpringHill Suites by Marriott Chula Vista Eastlake

SpringHill Suites by Marriott Chula Vista Eastlake
3.5 star property
23.9 km from Serra Mesa
9.6 out of 10, Exceptional, (604 reviews)
"Front desk staff at check in was very helpful in making sure we got the room we booked. Room was clean and spacious. Thank you SpringHill Suites."
United States
Elizabeth
The price is 4.742.640 ₫
5.226.151 ₫ total
includes taxes & fees
19 Apr - 20 Apr
SpringHill Suites by Marriott Chula Vista Eastlake

Embassy Suites by Hilton San Diego Bay Downtown

Embassy Suites by Hilton San Diego Bay Downtown
4.0 star property
10.6 km from Serra Mesa
9.0 out of 10, Wonderful, (1,689 reviews)
"Wonderful hotel and great location!! "
United States
Jan
The price is 4.860.284 ₫
6.590.980 ₫ total
includes taxes & fees
2 Apr - 3 Apr
Embassy Suites by Hilton San Diego Bay Downtown

HYATT house San Diego/Sorrento Mesa

HYATT house San Diego/Sorrento Mesa
3.0 star property
11.8 km from Serra Mesa
9.0 out of 10, Wonderful, (1,000 reviews)
"Enjoyed our stay very much "
United States
Peggy Sue
The price is 3.794.112 ₫
4.361.142 ₫ total
includes taxes & fees
2 Apr - 3 Apr
HYATT house San Diego/Sorrento Mesa

Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy
4.0 star property
Little Italy, 9.3 km from Serra Mesa
9.0 out of 10, Wonderful, (460 reviews)
"Location is great! Really good stay for an experience in downtown San Diego "
United States
Umberto
The price is 3.661.677 ₫
4.245.438 ₫ total
includes taxes & fees
5 Apr - 6 Apr
Courtyard by Marriott San Diego Downtown Little Italy

Comfort Inn Sea World Area

Comfort Inn Sea World Area
3.5 star property
8.2 km from Serra Mesa
8.6 out of 10, Excellent, (3,517 reviews)
"Breakfast buffet was exceptional."
United States
Catherine
The price is 2.686.986 ₫
3.088.556 ₫ total
includes taxes & fees
26 Apr - 27 Apr
Comfort Inn Sea World Area

The Beau Hotel Gaslamp Quarter San Diego

The Beau Hotel Gaslamp Quarter San Diego
3.0 star property
Gaslamp Quarter, 9.9 km from Serra Mesa
9.0 out of 10, Wonderful, (659 reviews)
"Staff , location and room service was great "
United States
Brian
The price is 4.001.998 ₫
4.552.273 ₫ total
includes taxes & fees
6 Apr - 7 Apr
The Beau Hotel Gaslamp Quarter San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Serra Mesa

Find the best Serra Mesa areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Harlem of the West Sites – discover Gaslamp Quarter, a destination also famous for its shopping.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Dog Beach and Sunset Cliffs Natural Park.

Top Serra Mesa Hotel Reviews

Frequently asked questions

What's it like in Serra Mesa?
Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighbourhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.
How many hotels can I expect to find in the Serra Mesa area?
Expedia has 39 hotels and other accommodation options in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.
If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?
Yes, most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Serra Mesa.
What can I see and do in this San Diego neighbourhood?
Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.