Sanibel Isles Travel Guide

Sanibel

A sandy beach with a lighthouse and a house surrounded by trees.
A sandy beach with a lighthouse, palm trees, and a house in the background.
A coastal lighthouse with a brick tower, surrounded by beach houses and palm trees.


Top hotels in Sanibel Isles

Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
The price is 5.893.382 ₫ per night from 13 Jul to 14 Jul
5.893.382 ₫
7.890.755 ₫ total
13 Jul - 14 Jul
includes taxes & fees
Stay at this beach hotel in Fort Myers Beach. Enjoy free Wi-Fi, a full-service spa and 4 restaurants. Our guests praise the pool and the helpful staff in their ...
9/10 Wonderful! (2,262 reviews)
"Beautiful and clean as always!"

Reviewed on 27 Jun 2026

Margaritaville Beach Resort Fort Myers
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd Fort Myers Beach FL
The price is 4.181.382 ₫ per night from 1 Jul to 2 Jul
4.181.382 ₫
5.248.686 ₫ total
1 Jul - 2 Jul
includes taxes & fees
Stay at this beach hotel in Fort Myers Beach. Enjoy free Wi-Fi, 3 restaurants and a beach locale. Popular attractions Key West Express and Estero Boulevard Beach ...
9/10 Wonderful! (1,666 reviews)
"The staff were all friendly & helpful. The restaurants have lots to choose from & everything was outstanding!! The beach view was everything I was hoping for!!! The beach sand was fluffy & soft & the guys who handle it take care of making it always look pretty! My only complaint would be they start ..."

Reviewed on 28 Jun 2026

Lani Kai Beachfront Resort
Sanibel Island Beach Resort

Sanibel Island Beach Resort

3 out of 5
1231 Middle Gulf Dr Sanibel FL
The price is 6.022.242 ₫ per night from 1 Jul to 2 Jul
6.022.242 ₫
7.372.251 ₫ total
1 Jul - 2 Jul
includes taxes & fees
Stay at this beach hotel in Sanibel. Enjoy free Wi-Fi, free parking and a beach locale. Our guests praise the pool and the restaurant in their reviews. Popular ...
9.2/10 Wonderful! (2,060 reviews)
"Only thing we were disappointed in was the 7pm pool closing time. For such hot weather, we were very surprised to not have the chance for some evening swimming. Food at the BRGR Lounge was great! We appreciated the blue & white towels for the beach and the ease in switching them out. Thank you, Steve ..."

Reviewed on 26 Jun 2026

Sanibel Island Beach Resort
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

4 out of 5
17260 Harbour Pointe Dr Fort Myers FL
The price is 5.448.946 ₫ per night from 16 Jul to 17 Jul
5.448.946 ₫
6.996.005 ₫ total
16 Jul - 17 Jul
includes taxes & fees
Stay at this spa resort in Fort Myers. Enjoy 3 outdoor pools, a full-service spa and 4 restaurants. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,006 reviews)
"As soon as we arrived they helped us with bags and all other necessities! Everyone was very kind and helpful, especially bc I was with my adult special needs daughter,,,,, everyone made out stay very comfortable. Edna, the server by the pool was super nice and helpful ,, we will come back ..."

Reviewed on 27 Jun 2026

Marriott Sanibel Harbour Resort & Spa
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

2.5 out of 5
1538 Cape Coral Pkwy E Cape Coral FL
The price is 2.656.098 ₫ per night from 5 Jul to 6 Jul
2.656.098 ₫
2.961.549 ₫ total
5 Jul - 6 Jul
includes taxes & fees
Stay at this business-friendly hotel in Cape Coral. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,545 reviews)
"Great hotel in the heart of Cape Coral!! Mary Jane is amazing!!!! So pleasant and she goes above and beyond to ensure a wonderful stay!"

Reviewed on 28 Jun 2026

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Baymont by Wyndham Fort Myers Central

Baymont by Wyndham Fort Myers Central

2.5 out of 5
4850 S Cleveland Ave Fort Myers FL
The price is 1.656.774 ₫ per night from 1 Jul to 2 Jul
1.656.774 ₫
1.847.435 ₫ total
1 Jul - 2 Jul
includes taxes & fees
Stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...
6.8/10 (1,128 reviews)
"I was recommended to stay here and let’s just say never again"

Reviewed on 27 Jun 2026

Baymont by Wyndham Fort Myers Central
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Sanibel Isles

Find the best Sanibel Isles areas for the activities you enjoy most.

Mid Island

If you're spending some time in Mid Island, Sanibel Island Southern Beach and Periwinkle Way are top sights worth seeing.

West End

If you're spending some time in West End, Sanibel Island Southern Beach and J. N. Ding Darling National Wildlife Refuge are top sights worth seeing.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Southern Beach and Sanibel Island Northern Beach.

Beachview Country Club Estates

While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.

Gulf Shores

When in Gulf Shores, you can plan a visit to Bowman's Beach and J. N. Ding Darling National Wildlife Refuge, some noteworthy sights in the nearby area.



Sanibel Isles Travel Guide

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