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Our top choices for Sanibel Isles hotels

HomeTowne Studios by Red Roof Fort Myers

HomeTowne Studios by Red Roof Fort Myers
2.5 star property
26.4 km from Sanibel Isles
The price is 1.775.621 ₫
1.979.817 ₫ total
includes taxes & fees
18 May - 19 May
HomeTowne Studios by Red Roof Fort Myers

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
10.3 km from Sanibel Isles
9.0 out of 10, Wonderful, (1,476 reviews)
"Beach view fabulous, all the staff was very helpful and polite "
United States
Shari
The price is 4.477.712 ₫
5.579.674 ₫ total
includes taxes & fees
14 May - 15 May
Lani Kai Beachfront Resort

The Bay Inn at Lani Kai

The Bay Inn at Lani Kai
3.0 star property
10.3 km from Sanibel Isles
7.6 out of 10, Good, (407 reviews)
"front desk workers were extremely pleasant"
United States
Dave
The price is 3.393.861 ₫
4.370.845 ₫ total
includes taxes & fees
19 May - 20 May
The Bay Inn at Lani Kai

Pointe Estero Beach Resort

Pointe Estero Beach Resort
2.0 star property
15.8 km from Sanibel Isles
9.2 out of 10, Wonderful, (1,009 reviews)
"Love this place!!"
United States
Teneille
The price is 4.258.112 ₫
13.292.036 ₫ total
includes taxes & fees
17 May - 18 May
Pointe Estero Beach Resort

The Anchor Inn

The Anchor Inn
2.0 star property
Mid Island, 2.3 km from Sanibel Isles
10.0 out of 10, Exceptional, (35 reviews)
"Anchor Inn is not only in a great location but beautiful. We used the bikes every day!"
United States
Renee
The price is 5.277.585 ₫
6.279.142 ₫ total
includes taxes & fees
31 May - 1 Jun
The Anchor Inn

StudioRes by Marriott Fort Myers Airport

StudioRes by Marriott Fort Myers Airport
3.0 star property
25.4 km from Sanibel Isles
9.4 out of 10, Exceptional, (54 reviews)
"Great hotel and free clean and friendly staff"
United States
cynthia
The price is 2.213.902 ₫
2.468.501 ₫ total
includes taxes & fees
18 May - 19 May
StudioRes by Marriott Fort Myers Airport

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island, 3.2 km from Sanibel Isles
9.2 out of 10, Wonderful, (1,881 reviews)
"Loved the room and the location, the grounds were beautiful and had a convenient beach access, very charming!"
United States
Hillary
The price is 6.817.916 ₫
8.260.077 ₫ total
includes taxes & fees
31 May - 1 Jun
Sanibel Island Beach Resort

La Quinta Inn & Suites by Wyndham Bonita Springs Naples N.

La Quinta Inn & Suites by Wyndham Bonita Springs Naples N.
3.0 star property
29.4 km from Sanibel Isles
9.0 out of 10, Wonderful, (1,401 reviews)
"Great place! "
United States
Ben
The price is 2.525.664 ₫
2.816.115 ₫ total
includes taxes & fees
18 May - 19 May
La Quinta Inn & Suites by Wyndham Bonita Springs Naples N.

Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina
4.0 star property
9 km from Sanibel Isles
9.4 out of 10, Exceptional, (1,352 reviews)
"Great stay!"
United States
John
Pink Shell Beach Resort and Marina

Holiday Inn Express & Suites Fort Myers Airport by IHG

Holiday Inn Express & Suites Fort Myers Airport by IHG
2.5 star property
27.6 km from Sanibel Isles
9.6 out of 10, Exceptional, (1,030 reviews)
"Very nice stay"
United States
James
The price is 2.600.021 ₫
2.899.062 ₫ total
includes taxes & fees
1 Jun - 2 Jun
Holiday Inn Express & Suites Fort Myers Airport by IHG

Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
8.5 km from Sanibel Isles
8.8 out of 10, Excellent, (1,004 reviews)
"Wonderful location and accommodations!"
United States
Karen
The price is 2.709.827 ₫
3.021.458 ₫ total
includes taxes & fees
13 May - 14 May
Residence Inn by Marriott Fort Myers Sanibel

Park Motel

Park Motel
2.5 star property
30.1 km from Sanibel Isles
9.2 out of 10, Wonderful, (46 reviews)
"Clean, quiet, very friendly and helpful staff, hot tub in room very relaxing."
United States
Kristeen
The price is 2.486.200 ₫
2.772.112 ₫ total
includes taxes & fees
13 May - 14 May
Park Motel

Latitude 26 Waterfront Boutique Resort - Bonita Springs

Latitude 26 Waterfront Boutique Resort - Bonita Springs
3.0 star property
26.8 km from Sanibel Isles
8.8 out of 10, Excellent, (776 reviews)
"Beautiful property and views."
United States
Nicole
The price is 3.025.535 ₫
3.449.110 ₫ total
includes taxes & fees
17 May - 18 May
Latitude 26 Waterfront Boutique Resort - Bonita Springs

Latitude 26 Waterfront Resort & Marina

Latitude 26 Waterfront Resort & Marina
3.0 star property
10.8 km from Sanibel Isles
8.6 out of 10, Excellent, (1,008 reviews)
"Place is quiet and right down the street from the beach"
United States
Bryan
The price is 2.783.492 ₫
3.103.594 ₫ total
includes taxes & fees
13 May - 14 May
Latitude 26 Waterfront Resort & Marina

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
10.3 km from Sanibel Isles
8.8 out of 10, Excellent, (1,015 reviews)
"Amazing place to stay! "
United States
Kristen
The price is 2.382.543 ₫
2.656.420 ₫ total
includes taxes & fees
13 May - 14 May
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Woodspring Suites Fort Myers - Cape Coral

Woodspring Suites Fort Myers - Cape Coral
2.5 star property
23.4 km from Sanibel Isles
7.4 out of 10, Good, (286 reviews)
"Real good experience for a short stay"
United States
Victor
The price is 1.683.776 ₫
1.877.410 ₫ total
includes taxes & fees
13 May - 14 May
Woodspring Suites Fort Myers - Cape Coral

Best Western Plus Beach Resort

Best Western Plus Beach Resort
2.5 star property
9.4 km from Sanibel Isles
9.4 out of 10, Exceptional, (1,006 reviews)
"We enjoyed staying right on the beach. Grounds were clean and well kept, and the pool was lovely."
United States
Laura Elizabeth
The price is 7.301.537 ₫
8.141.214 ₫ total
includes taxes & fees
1 Jun - 2 Jun
Best Western Plus Beach Resort

Tween Waters Island Resort & Spa

Tween Waters Island Resort & Spa
3.0 star property
14.4 km from Sanibel Isles
8.6 out of 10, Excellent, (1,004 reviews)
"View from room was amazing. "
United States
Timothy
The price is 7.163.941 ₫
8.908.610 ₫ total
includes taxes & fees
13 May - 14 May
Tween Waters Island Resort & Spa

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
3.0 star property
9.1 km from Sanibel Isles
8.2 out of 10, Very good, (1,148 reviews)
"Clean room, nice pool, near beaches, good breakfast."
United States
Kenneth
The price is 2.511.310 ₫
2.800.110 ₫ total
includes taxes & fees
12 Jun - 13 Jun
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

Hampton Inn & Suites Fort Myers-Estero/FGCU

Hampton Inn & Suites Fort Myers-Estero/FGCU
2.5 star property
27.5 km from Sanibel Isles
9.2 out of 10, Wonderful, (1,011 reviews)
"The front desk clerk was very friendly and made sure I had a quick and smooth check in. The room was great and the bed was very comfortable."
United States
Shandi
The price is 2.234.118 ₫
2.491.042 ₫ total
includes taxes & fees
10 Jun - 11 Jun
Hampton Inn & Suites Fort Myers-Estero/FGCU
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Sanibel Isles

Find the best Sanibel Isles areas for the activities you enjoy most.

Mid Island

If you're spending some time in Mid Island, Periwinkle Way and Sanibel Island Southern Beach are top sights worth seeing.

West End

If you're spending some time in West End, J. N. Ding Darling National Wildlife Refuge and Bowman's Beach are top sights worth seeing.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

Beachview Country Club Estates

While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.

Sanctuary

While there might not be top attractions in Sanctuary, you can explore the larger area and discover places like Blind Pass Beach and Turner Beach.

Top Sanibel Isles Hotel Reviews

Frequently asked questions

What's it like in Sanibel Isles?
Travellers to the Sanibel Isles neighbourhood in Sanibel will be sure to enjoy their stay.
How many hotels should I expect to find in the Sanibel Isles area?
When you want to find places to stay in Sanibel, start by booking one of Expedia's 9 hotels and other accommodation options in Sanibel Isles.
If I need to cancel my hotel reservation in Sanibel Isles, will I receive a refund?
Yes! The majority of hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within 24 hours of booking. Put your dates in and click on "Search", then filter by "fully refundable" to view top deals in Sanibel Isles.
What is there to do in this Sanibel neighbourhood?
Woodring Point, Woodring Beach and Dunes Golf and Tennis Club are just a few of the places to visit in and around Sanibel Isles. Bailey's Beach and Periwinkle Way are also worth a visit when you're out sightseeing in Sanibel.