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Our top choices for Sanibel Isles hotels

Garden
Kona Kai Motel

Kona Kai Motel

Kona Kai Motel
Mid Island, 2.4 km from Sanibel Isles
9.0 out of 10, Wonderful, (941)
"Spacious rooms, friendly staff, quiet surroundings."
United States
James
The price is 4.190.763 ₫
4.813.052 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Kona Kai Motel
BBQ/picnic Area
Matlacha on Shoreview

Matlacha on Shoreview

Matlacha on Shoreview
2.0 star property
19.4 km from Sanibel Isles
9.6 out of 10, Exceptional, (210)
"Place was great. Nice and neat perfect for what i needed."
United States
Michael
The price is 1.186.065 ₫
3.085.746 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Matlacha on Shoreview
Restaurant
Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers

Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers

Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers
3.0 star property
25.4 km from Sanibel Isles
9.4 out of 10, Exceptional, (743)
"Nice hotel "
United States
Decoste
The price is 3.663.623 ₫
4.084.939 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers
Suite, 2 Bedrooms, Marina View | Egyptian cotton sheets, premium bedding, pillow-top beds, in-room safe
The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
10.1 km from Sanibel Isles
9.0 out of 10, Wonderful, (1002)
"Excellent stay over Thanksgiving holiday!"
United States
Nicole
The price is 3.855.502 ₫
5.300.393 ₫ total
includes taxes & fees
21 Dec - 22 Dec
The Westin Cape Coral Resort At Marina Village
Lobby
Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
2.5 star property
14.5 km from Sanibel Isles
8.6 out of 10, Excellent, (1002)
"The rooms were clean, staff were very friendly and accommodating."
United States
Sandra
The price is 2.509.186 ₫
2.797.743 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
Terrace/patio
Dolphin Key Resort

Dolphin Key Resort

Dolphin Key Resort
3.0 star property
15.3 km from Sanibel Isles
8.8 out of 10, Excellent, (1205)
"Very nice staff, great shower set up, the on site restaurant was very good. "
United States
Chuck
The price is 2.635.700 ₫
2.938.806 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Dolphin Key Resort
Balcony view
OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL
2.5 star property
17.5 km from Sanibel Isles
5.8 out of 10, (1003)
"Beautiful place "
United States
Blaine
The price is 1.991.535 ₫
2.405.076 ₫ total
includes taxes & fees
13 Dec - 14 Dec
OYO Waterfront Hotel - Cape Coral/Fort Myers, FL
In-room safe, desk, laptop workspace, blackout curtains
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
15.5 km from Sanibel Isles
9.4 out of 10, Exceptional, (1031)
"Hotel was very clean and the breakfast had a great variety."
United States
Lynn
The price is 2.978.341 ₫
3.320.850 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Luxury Room | Bathroom | Towels, soap, shampoo, toilet paper
Park Motel

Park Motel

Park Motel
2.5 star property
30.1 km from Sanibel Isles
9.6 out of 10, Exceptional, (23)
"Amazing place 🙌🙌"
United States
Carlos
The price is 2.633.064 ₫
2.935.867 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Park Motel
Deluxe Suite (Second Floor Only) | Terrace/patio
Off the Charts Inn & Out Island Resort

Off the Charts Inn & Out Island Resort

Off the Charts Inn & Out Island Resort
2.5 star property
5.1 km from Sanibel Isles
9.6 out of 10, Exceptional, (144)
"great boutique hotel in an amazing area on Pine Island Fl. Great restaurants and bars walkable and great fishing. "
United States
Pat
The price is 5.010.413 ₫
6.468.252 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Off the Charts Inn & Out Island Resort
Lobby
Tween Waters Island Resort & Spa

Tween Waters Island Resort & Spa

Tween Waters Island Resort & Spa
3.0 star property
14.4 km from Sanibel Isles
8.6 out of 10, Excellent, (1001)
"Stunning Beach View great Staff "
United States
Robert
The price is 8.407.883 ₫
10.297.284 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Tween Waters Island Resort & Spa
Terrace/patio
SpringHill Suites by Marriott Fort Myers Estero

SpringHill Suites by Marriott Fort Myers Estero

SpringHill Suites by Marriott Fort Myers Estero
2.5 star property
27.3 km from Sanibel Isles
9.2 out of 10, Wonderful, (816)
"Great customer service, very clean, beautiful room, great breakfast "
United States
emma
The price is 3.400.053 ₫
3.922.976 ₫ total
includes taxes & fees
14 Dec - 15 Dec
SpringHill Suites by Marriott Fort Myers Estero
Desk, blackout curtains, iron/ironing board, free cots/infant beds
TownePlace Suites by Marriott Fort Myers Estero

TownePlace Suites by Marriott Fort Myers Estero

TownePlace Suites by Marriott Fort Myers Estero
3.5 star property
25.8 km from Sanibel Isles
9.4 out of 10, Exceptional, (461)
"Clean room and very nice staff"
United States
Nancy
The price is 3.663.623 ₫
4.085.071 ₫ total
includes taxes & fees
14 Dec - 15 Dec
TownePlace Suites by Marriott Fort Myers Estero
Lobby
Embassy Suites by Hilton Fort Myers Estero

Embassy Suites by Hilton Fort Myers Estero

Embassy Suites by Hilton Fort Myers Estero
3.5 star property
27.4 km from Sanibel Isles
9.2 out of 10, Wonderful, (1052)
"Good hotel nice and clean "
United States
Luis
The price is 3.668.894 ₫
4.090.817 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Embassy Suites by Hilton Fort Myers Estero
On the beach, sun-loungers, beach towels
Sanibel Island Beach Resort

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island, 3.2 km from Sanibel Isles
9.2 out of 10, Wonderful, (1462)
"Courteous staff, easy parking, close beach"
United States
Jenna
The price is 5.508.613 ₫
6.801.028 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Sanibel Island Beach Resort
Property entrance
Matlacha Tiny Village

Matlacha Tiny Village

Matlacha Tiny Village
3.0 star property
18.3 km from Sanibel Isles
8.8 out of 10, Excellent, (268)
"Very nice place with all necesary accommodations for a Pleasant stay. "
United States
isabel
The price is 3.060.048 ₫
5.388.953 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Matlacha Tiny Village
Lobby
Drury Inn & Suites Fort Myers Airport FGCU

Drury Inn & Suites Fort Myers Airport FGCU

Drury Inn & Suites Fort Myers Airport FGCU
3.0 star property
26.5 km from Sanibel Isles
9.8 out of 10, Exceptional, (1001)
"Room was clean and staff was outstanding!!"
United States
Marie
The price is 3.320.718 ₫
3.702.631 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Drury Inn & Suites Fort Myers Airport FGCU
Lobby
The Banyan Hotel Fort Myers, Tapestry Collection by Hilton

The Banyan Hotel Fort Myers, Tapestry Collection by Hilton

The Banyan Hotel Fort Myers, Tapestry Collection by Hilton
3.5 star property
27 km from Sanibel Isles
8.6 out of 10, Excellent, (835)
"Staff was friendly. "
United States
Jennifer
The price is 4.084.808 ₫
4.554.562 ₫ total
includes taxes & fees
23 Dec - 24 Dec
The Banyan Hotel Fort Myers, Tapestry Collection by Hilton
Exterior
Sundial Beach Resort & Spa

Sundial Beach Resort & Spa

Sundial Beach Resort & Spa
5.0 star property
Mid Island, 3.5 km from Sanibel Isles
8.6 out of 10, Excellent, (2584)
"wonderful family friendly and spotless resort"
United States
Mary Anne
The price is 9.464.799 ₫
11.993.266 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Sundial Beach Resort & Spa
View from property
Resort Harbour Properties

Resort Harbour Properties

Resort Harbour Properties
3.5 star property
5.1 km from Sanibel Isles
9.6 out of 10, Exceptional, (363)
"10/10 would stay there again"
United States
Kristie
Resort Harbour Properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Sanibel Isles

Find the best Sanibel Isles areas for the activities you enjoy most.
Fort Myers featuring a beach
Photo by Sanibel Captiva Chamber of Commerce/Milissa Sprecher Photography
Open Photo by Sanibel Captiva Chamber of Commerce/Milissa Sprecher Photography

West End

If you're spending some time in West End, J. N. Ding Darling National Wildlife Refuge and Bowman's Beach are top sights worth seeing.

Mid Island

If you're spending some time in Mid Island, Periwinkle Way and Sanibel Island Southern Beach are top sights worth seeing.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

Beachview Country Club Estates

While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.

Sanctuary

While there might not be top attractions in Sanctuary, you can explore the larger area and discover places like Blind Pass Beach and Turner Beach.

Top Sanibel Isles Hotel Reviews

Hyatt Vacation Club at Coconut Cove, Bonita Springs

Hyatt Vacation Club at Coconut Cove, Bonita Springs

10/10 Excellent
"Room great clean, staff great.loved pool"
Dennis 4-night trip
Posted 2 days ago
Hyatt Vacation Club at Coconut Cove, Bonita Springs

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Frequently asked questions

What's it like in Sanibel Isles?
Travellers to the Sanibel Isles neighbourhood in Sanibel will be sure to enjoy their stay.
How many hotels should I expect to find in the Sanibel Isles area?
When you want to find places to stay in Sanibel, start by booking one of Expedia's 7 hotels and other accommodation options in Sanibel Isles.
If I need to cancel my hotel reservation in Sanibel Isles, will I receive a refund?
Yes! The majority of hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within 24 hours of booking. Put your dates in and click on "Search", then filter by "fully refundable" to view top deals in Sanibel Isles.
What is there to do in this Sanibel neighbourhood?
Woodring Point, Woodring Beach and Dunes Golf and Tennis Club are just a few of the places to visit in and around Sanibel Isles. Bailey's Beach and Periwinkle Way are also worth a visit when you're out sightseeing in Sanibel.