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Check prices for these dates

Tonight
6 Nov - 7 Nov
Tomorrow
7 Nov - 8 Nov
This weekend
6 Nov - 8 Nov
Next weekend
13 Nov - 15 Nov

Our top choices for Santa Cruz hotels with a spa

A pool area with a thatched-roof structure, palm trees, and a staircase leading to an upper level.

1. Santa Cruz Plaza

Santa Cruz Plaza
4.0 star property
Santa Cruz
8.8 out of 10, Excellent, (378 reviews)
  • cleanliness
    Escape to a wellness sanctuary with a full-service spa offering hydrotherapy, body treatments, and massages in a tranquil setting.
The price is 2.963.520 ₫
2.963.520 ₫ total
6 Dec - 7 Dec
Santa Cruz Plaza
A room with a large window, a wooden table, and a chandelier.

2. Hotel Cava Colchagua

Hotel Cava Colchagua
4.0 star property
Santa Cruz
8.8 out of 10, Excellent, (178 reviews)
  • cleanliness
    Indulge in mineral springs and vineyard views at this wine country spa retreat with poolside serenity.
The price is 3.487.454 ₫
3.487.454 ₫ total
8 Nov - 9 Nov
Hotel Cava Colchagua
An outdoor dining area with wooden tables and chairs, surrounded by lush greenery and a glass door leading to a garden.

3. Hostal Vida 2000

Hostal Vida 2000
2.5 star property
Santa Cruz
6.6 out of 10, (4 reviews)
  • cleanliness
    Revitalising massages at B&B's full-service spa offer serene wellness escape with garden views.
The price is 821.792 ₫
821.792 ₫ total
8 Nov - 9 Nov
Hostal Vida 2000
A cozy room with a bed, a table, and a view of the outdoors through a triangular window.

4. Colchagua Tiny Lodge

Colchagua Tiny Lodge
3.5 star property
Santa Cruz
9.8 out of 10, Exceptional, (11 reviews)
  • cleanliness
    Tranquil cabin retreat offers private hot tubs, garden views, and massages in Colchagua's heart.
The price is 4.721.737 ₫
4.721.737 ₫ total
8 Nov - 9 Nov
Colchagua Tiny Lodge
A modern outdoor pool area with lounge chairs, a covered patio, and a brick pool.

5. Noi Blend Colchagua

Noi Blend Colchagua
3.0 star property
Palmilla
8.8 out of 10, Excellent, (159 reviews)
  • cleanliness
    Luxurious massage sanctuary with hot stone treatments and private spa rooms in wine country setting.
The price is 4.293.863 ₫
4.293.863 ₫ total
8 Nov - 9 Nov
Noi Blend Colchagua
A wooden interior with a large window, wooden flooring, and a sink.

6. Vik Chile

Vik Chile
5.0 star property
San Vicente
9.2 out of 10, Wonderful, (231 reviews)
  • cleanliness
    Pamper yourself at this national park hotel with rejuvenating spa treatments, sauna, and outdoor pool for ultimate relaxation.
The price is 19.790.243 ₫
19.790.243 ₫ total
11 Nov - 12 Nov
Vik Chile
A room with a brick ceiling, a bed, a massage table, a clock, and shelves with bottles.

7. Hotel Viña La Playa

Hotel Viña La Playa
3.5 star property
Peralillo
8.4 out of 10, Very good, (19 reviews)
  • cleanliness
    Vineyard spa retreat offers rainfall showers, outdoor pool, and tennis court for restorative wine country escapes.
The price is 5.478.744 ₫
5.478.744 ₫ total
26 Nov - 27 Nov
Hotel Viña La Playa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Santa Cruz

Pool
Breakfast included

Top Santa Cruz Hotel Reviews

A pool area with a thatched-roof structure, palm trees, and a staircase leading to an upper level.
Santa Cruz Plaza

Santa Cruz Plaza

Santa Cruz Plaza
Santa Cruz

10/10 Excellent

The service from the staff is immaculate. The properly full of charm and character. The rooms are spacious, clean and comfortable
United Kingdom
Darren
Reviewed November 3, 2026
Santa Cruz Plaza

Frequently Asked Questions

Looking for a spa hotel in Santa Cruz?

Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Make sure you enjoy the wineries during your stay. Hotels with spas are the perfect way to break out of your routine and add a layer of luxury to your stay.

How many spa hotels will I find in Santa Cruz?

Among Expedia's 36 accommodation options in Santa Cruz, there are 3 spa hotels.

What's there to see and do in Santa Cruz?

When you're in Santa Cruz, enjoy exploring the sights and attractions here including Casino Colchagua, Colchagua Campo y Vino and Lapostolle Clos Apalta Winery. If you have some spare time during your trip, you might want to check out Millahue Valley and Museo de Colchagua.

What is a Santa Cruz spa hotel?

Spa hotels in Santa Cruz provide lodging and have an on-site spa which offers services such as facials and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on holiday.