Search Holiday Rentals in Santa Cruz

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
23 Jan - 25 Jan
In two months
6 Mar - 8 Mar
In three months
3 Apr - 5 Apr
In four months
1 May - 3 May

Our top choices for Santa Cruz holiday rentals

Outdoor pool, open 9:00 AM to 8:00 PM, pool loungers
Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (82 reviews)
"Good price, great hotel!"
United States
James
The price is 1.024.374 ₫
1.024.374 ₫ total
includes taxes & fees
16 Jan - 17 Jan
Premium Suites Deluxe Aparthotel Equipetrol
Standard Suite, 1 Queen Bed | Hypo-allergenic bedding, down duvets, desk, laptop workspace
Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel
2.5 star property
Santa Cruz
8.8 out of 10, Excellent, (9 reviews)
"Perfect hotel"
Turkey
Yener
Equipetrol Suites Apart Hotel
1 bedroom, in-room safe, desk, iron/ironing board
Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (98 reviews)
"Yes, staff were very friendly "
United States
veronica
Apart Hotel Premium Suites Santa Cruz
Outdoor pool
AMERICA APARTMENTS

AMERICA APARTMENTS

AMERICA APARTMENTS
3.0 star property
Santa Cruz
The price is 1.444.630 ₫
1.444.630 ₫ total
includes taxes & fees
12 Jan - 13 Jan
AMERICA APARTMENTS
Front of property
Apart Hotel Toborochi

Apart Hotel Toborochi

Apart Hotel Toborochi
3.0 star property
Santa Cruz
8.8 out of 10, Excellent, (60 reviews)
"Property is close to nice dining options and entertainment places in Santa Cruz. The room is confortable and spacious "
United States
Stefany
Apart Hotel Toborochi
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santa Cruz Hotel Reviews

Lido Hotel

Lido Hotel

10/10 Excellent
"We stayed at the fabulous Lido Hotel for 2 nights in December 2025. The hotel is located in central Santa Cruz, within a 4 block walk from Plaza 24 de Septiembre, and also a short 10 minute walk from the iconic Cristo Redentor statue. Check in was quick and painless, and the front desk staff was friendly and helpful. The room itself was spacious, clean and comfortable, with a large attached full bathroom. The air conditioner did a great job of cooling the room. Breakfast was served each morning in the attached Chinese restaurant, and featured eggs, breakfast meats, fruits, juices, cereal and yogurt, and was a great way to fuel up before venturing out to explore Santa Cruz. Without equivocation, I highly recommend the Lido Hotel to anyone in search of a clean comfortable hotel at an affordable price in the enchanting metrolopolis of Santa Cruz de la Sierra, Bolivia. Dr. Kingstone Shih and Laura Meneses Los Altos, California USA "
kingstone 2-night trip
Posted 4 days ago
Lido Hotel

Frequently asked questions

Can I find a holiday rental in Santa Cruz?

Yes, there are holiday rentals in Santa Cruz close to Santa Cruz Zoo, or you can select a more secluded option if you're looking for a relaxing stay. Discover why Santa Cruz is known for its shops. Make sure you have time to check out the cafés and zoo during your trip.

How many holiday rentals will I find in Santa Cruz?

With 23 Expedia holiday rentals, you're guaranteed to find just the right place for your Santa Cruz stay.

What can I see and do in Santa Cruz?

Enjoy the outdoors at Guembe Biocenter and Lomas de Arena Regional Park, or simply take in cultural attractions like Cine Center and Sacred Art Museum. Plaza 24 de Septiembre and Ramon Tahuichi Aguilera Stadium are other places to visit while you're in town.

What are holiday rentals like in Santa Cruz?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Santa Cruz. Holiday rentals feature amenities such as kitchens and laundry facilities to help you enjoy your stay. If you're concerned about a clean environment, holiday rentals can provide a sense of privacy away from shared hotel lifts and lobbies bustling with people while still allowing you the excitement and enjoyment of travel. You'll also find more space in a holiday rental than in a standard hotel, which makes a holiday rental a popular choice for family gatherings.