Search Hotels Near Santa Fe River,

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
16 Dec - 17 Dec
Tomorrow
17 Dec - 18 Dec
This weekend
19 Dec - 21 Dec
Next weekend
26 Dec - 28 Dec

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Fe River hotels

Standard Cabin, 1 Queen Bed | Exterior
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
2.0 star property
8.3 km from Santa Fe River
10.0 out of 10, Exceptional, (151)
"Fantastic place! Very nice amenities and service was wonderful"
United States
Annette
The price is 2.604.393 ₫
4.022.340 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
Reception
BlueGem Motel

BlueGem Motel

BlueGem Motel
2.0 star property
9.6 km from Santa Fe River
9.2 out of 10, Wonderful, (393)
"Perfect "
United States
Geily
The price is 2.900.873 ₫
3.263.483 ₫ total
includes taxes & fees
17 Dec - 18 Dec
BlueGem Motel
Double Room, Non Smoking | Laptop workspace, free WiFi
High Springs Country Inn

High Springs Country Inn

High Springs Country Inn
2.0 star property
9.4 km from Santa Fe River
8.4 out of 10, Very good, (16)
"Great remodel of a retro motel."
United States
Kathleen
The price is 2.059.838 ₫
2.317.317 ₫ total
includes taxes & fees
21 Dec - 22 Dec
High Springs Country Inn
Exterior
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
17.6 km from Santa Fe River
9.4 out of 10, Exceptional, (1005)
"Staff was great and the location is perfect ! "
United States
JAY
The price is 2.972.691 ₫
3.344.277 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Breakfast area
Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
2.5 star property
18 km from Santa Fe River
9.4 out of 10, Exceptional, (473)
"Staff very helpful- clean updated facility. "
United States
bethany
The price is 2.504.426 ₫
2.817.479 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Hampton Inn & Suites Alachua I-75
1 bedroom, laptop workspace, free WiFi, bed sheets
Vista Verde Farm Retreat

Vista Verde Farm Retreat

Vista Verde Farm Retreat
2.0 star property
17.1 km from Santa Fe River
9.6 out of 10, Exceptional, (12)
"This is my second time staying on this property and I love it "
United States
brandie
The price is 2.679.877 ₫
4.772.272 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Vista Verde Farm Retreat
Room, 1 King Bed with Sofa bed, Non Smoking | Desk, laptop workspace, blackout curtains, iron/ironing board
Alachua Inn

Alachua Inn

Alachua Inn
2.0 star property
18.7 km from Santa Fe River
5.8 out of 10, (656)
"Staff was very nice"
United States
Nekia
The price is 1.624.457 ₫
1.959.049 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Alachua Inn
Desk, blackout curtains, iron/ironing board, rollaway beds
Americas Best Value Inn Alachua

Americas Best Value Inn Alachua

Americas Best Value Inn Alachua
2.0 star property
17.9 km from Santa Fe River
4.8 out of 10, (599)
"Staff was helpful and so courteous.."
United States
Christian
The price is 1.677.071 ₫
1.887.001 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Americas Best Value Inn Alachua
Outdoor pool
Travelers Inn

Travelers Inn

Travelers Inn
2.0 star property
38.8 km from Santa Fe River
6.4 out of 10, (402)
"Older property "
United States
Russell
The price is 1.841.490 ₫
2.071.676 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Travelers Inn
Lobby sitting area
Motel 6 Starke, FL

Motel 6 Starke, FL

Motel 6 Starke, FL
2.0 star property
58.5 km from Santa Fe River
6.0 out of 10, (694)
"Rooms were clean & comfortable. Staff is also friendly "
United States
Rogers
The price is 1.422.156 ₫
1.578.593 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Motel 6 Starke, FL
Free daily continental breakfast
Quality Inn Alachua - Gainesville Area

Quality Inn Alachua - Gainesville Area

Quality Inn Alachua - Gainesville Area
2.5 star property
18.5 km from Santa Fe River
7.2 out of 10, Good, (1005)
"The hotel staff was excellent at check-in and check out. "
United States
Edward
The price is 1.967.501 ₫
2.213.439 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Quality Inn Alachua - Gainesville Area
Premium bedding, desk, blackout curtains, soundproofing
Palms Garden Inn

Palms Garden Inn

Palms Garden Inn
2.0 star property
20.3 km from Santa Fe River
7.4 out of 10, Good, (579)
"Clean and nice staff "
United States
apollo
The price is 1.708.640 ₫
1.922.253 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Palms Garden Inn
Standard Double Room | Desk, laptop workspace, iron/ironing board, free WiFi
Soho Inn Waldo

Soho Inn Waldo

Soho Inn Waldo
51.5 km from Santa Fe River
The price is 1.841.577 ₫
2.071.774 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Soho Inn Waldo
House (3 Bedrooms) | Front of property
Chic Farm Glamping Exclusive Perks

Chic Farm Glamping Exclusive Perks

Chic Farm Glamping Exclusive Perks
3.0 star property
75.3 km from Santa Fe River
The price is 3.761.901 ₫
6.990.560 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Chic Farm Glamping Exclusive Perks
Outdoor pool
Best Western Waldo Inn and Suites

Best Western Waldo Inn and Suites

Best Western Waldo Inn and Suites
2.5 star property
51.2 km from Santa Fe River
8.8 out of 10, Excellent, (950)
"Room was clean, staff was very friendly, loved the breakfast"
United States
Christina
The price is 2.604.130 ₫
2.929.548 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Best Western Waldo Inn and Suites
Free daily full breakfast
Holiday Inn Express Starke by IHG

Holiday Inn Express Starke by IHG

Holiday Inn Express Starke by IHG
2.5 star property
56.4 km from Santa Fe River
9.6 out of 10, Exceptional, (401)
"Excellent staff, clean room, amenities."
United States
Maria
The price is 2.499.640 ₫
2.774.600 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Holiday Inn Express Starke by IHG
Outdoor pool
Americas Best Value Inn Starke

Americas Best Value Inn Starke

Americas Best Value Inn Starke
2.0 star property
58.4 km from Santa Fe River
7.4 out of 10, Good, (526)
"I love the rooms it's nice size bed for me and my boyfriend and I love the tub, got 2 have the tub"
United States
Tasha
The price is 2.078.253 ₫
2.306.860 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Americas Best Value Inn Starke
Apartment (1 Bedroom) | Floor plan
Dreamy Covered Wagon Farm Experience

Dreamy Covered Wagon Farm Experience

Dreamy Covered Wagon Farm Experience
2.0 star property
75.3 km from Santa Fe River
The price is 3.367.936 ₫
6.001.240 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Dreamy Covered Wagon Farm Experience
Exterior
Best Western Starke

Best Western Starke

Best Western Starke
2.5 star property
58.6 km from Santa Fe River
8.6 out of 10, Excellent, (662)
"staff was great but construction was noisy."
United States
Duane
The price is 2.078.253 ₫
2.306.861 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Best Western Starke
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Santa Fe River Hotel Reviews

Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy

10/10 Excellent
"Can’t wait to go back! Such a cute setup. Like the best of both camping and having a hotel room. Great location for exploring all the state parks in the area, very close to downtown High Springs. Amenities are great - s’mores kit, coffee, snacks, firewood. The cabins are situated so you don’t see anyone else from the picture window or campfire but you’re close to neighbors so you feel safe, not secluded. Sleeping with the window shade open and seeing the stars and moon was great too. "
Ashley 1-night trip
Posted 4 days ago
Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy
High Springs Country Inn

High Springs Country Inn

10/10 Excellent
"Older roadside motel on the outside, but fully renovated interior on the inside. "
Horace 1-night trip
Posted 3 months ago
High Springs Country Inn

Hotels near other Santa Fe River attractions

Blue waters of the spring basin drop down to the rocky cavern entrance at Ginnie Ballroom, Ginnie Springs, Florida

Ginnie Spring

Commune with nature and explore the great outdoors at Ginnie Spring during your travels in High Springs. Amble around the area's parks or visit its shops.
See properties
My boyfriend Joe went for an early morning swim in the springs. We were camping in the park for the weekend. I took this from the jumping platform.
Photo by Laurie Karner
Open Photo by Laurie Karner

Ruth B. Kirby Gilchrist Blue Springs State Park

4.6/5 (40 reviews)
You can take time to visit Ruth B. Kirby Gilchrist Blue Springs State Park during your travels to High Springs. Discover the area's restaurants or seek out the kayaking spots.
See properties

Frequently asked questions

What's the area like around Santa Fe River?
If you're planning to come to the area to visit Santa Fe River, take some time to see the rest of the sights while you're in town. This family-friendly area is known for its array of dining options and sporting events. You'll find 24 hotels and other accommodations within a few miles for a convenient home base.
How many hotels can I expect to find close to Santa Fe River?
Expedia has 24 hotels and other accommodation options a few miles from Santa Fe River.
If I need to cancel the hotel reservation for my stay near Santa Fe River, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to get top deals close to Santa Fe River.

Explore a world of travel with Expedia