Santa Lucia Holidays

Book a Hotel + Flight or Car together to unlock savings

Photo by William Keller

Where to stay in Santa Lucia

Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most. Learn more about Santa Lucia
Ancient ruins with stone columns and a building with green shutters in the background.

Ortigia

4 out of top 10 points of interest in this area
4.5/5(49 area reviews)

Ortigia is popular for its seaside views, and if you're looking for more to see and do, you might think about a trip to Cathedral of Syracuse or Piazza del Duomo.

Find hotels in Ortigia

Top hotels in Santa Lucia

Grande Albergo Alfeo

Grande Albergo Alfeo

4 out of 5
Via Nino Bixio 5 Syracuse SR
Fully refundableReserve now, pay when you stay
The price is 3.502.653 ₫ per night from 12 Jul to 13 Jul
3.502.653 ₫
3.993.013 ₫ total
12 Jul - 13 Jul
includes taxes & fees
8.6/10 Excellent! (683 reviews)
"We stayed here for a few nights and had a great experience from start to finish. The room was very clean, the staff was welcoming and helpful whenever we needed anything, and the breakfast had plenty of fresh options each morning. The air conditioning worked flawlessly, which made the room especially ..."

Reviewed on 5 Jul 2026

Grande Albergo Alfeo
Caportigia Boutique Hotel

Caportigia Boutique Hotel

5 out of 5
Viale Montedoro 76 Syracuse SR
Fully refundableReserve now, pay when you stay
The price is 4.556.327 ₫ per night from 12 Jul to 13 Jul
4.556.327 ₫
5.312.979 ₫ total
12 Jul - 13 Jul
includes taxes & fees
9.4/10 Exceptional! (283 reviews)
"Valentina was so very lovely and helpful. She was very informative as well. The property is very beautiful and a great location. My only criticism is the sound the doors make when you unlock the room door. It’s a very load electronic buzzing sound. Late at night you can hear other people coming in ..."

Reviewed on 18 Jun 2026

Caportigia Boutique Hotel
Fortaleza Charme House

Fortaleza Charme House

Via Eritrea 6 Syracuse SR
Fully refundableReserve now, pay when you stay
The price is 5.213.041 ₫ per night from 15 Jul to 16 Jul
5.213.041 ₫
5.943.011 ₫ total
15 Jul - 16 Jul
includes taxes & fees
10/10 Exceptional! (34 reviews)
"Amazing stay. Very spacious room #104. I would highly recommend this place. Fransiesco was fantastic"

Reviewed on 3 Jul 2026

Fortaleza Charme House
See all 3,840 properties in Santa Lucia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Lucia holiday package cost?
Our Santa Lucia packages, which start from just , are the perfect way to save loads of cash. All you have to do is choose your preferred flights, hotels and rental cars to create your ideal escape.
How do I get a cheap travel package to Santa Lucia?
Combine your hotels and flights, throw in extras such as a rental car or activities, and save with a Santa Lucia holiday package. You won't just score big discounts on your escape — you'll have lots of choice at your fingertips too. When you book with Expedia, you can choose from more than 550 airlines and 1null000null000 hotels all over the world. Your affordable holiday begins right here, right now!
Where should I stay in Santa Lucia?
Take the hassle out of sightseeing by staying in a hotel right around the corner from Santa Lucia's iconic attractions. Cathedral of Syracuse and Temple of Apollo are two visitor favourites.
What are the top hotels in Santa Lucia?
If this will be your first time in Santa Lucia, book a room at Hotel Cavalieri or Paolanna Luxury Rooms. Both hotels offer friendly service and are popular options with many travellers.
How far in advance should I book my Santa Lucia holiday?
Smart travellers will likely want to reserve their seats early. You can normally compare international fares on Expedia up to 12 months before your flight. If you're purchasing tickets last minute, don't stress. Budget prices occasionally appear in the last weeks prior to departure.
What does an Expedia Santa Lucia travel package include?
Packages include hotels, flights and rental cars, but you can mix and match them to create your ideal Santa Lucia holiday. You can also add on some activities and experiences once you've made your booking. You're in charge! When you bundle your bookings with Expedia, you'll score discounts you won't find anywhere else.
What should I know before booking a Santa Lucia travel package?
You'll land impressive savings when you bundle your hotels, flights and rental cars into a package. Plus, booking everything in one place will make your trip planning easier. So why waste money or time? Whether you're putting together a ritzy romantic getaway or a budget family adventure, browse our package deals today.
Can I choose my airline with a Santa Lucia Expedia holiday package?
You can, and with more than 550 airlines to pick from globally, you have plenty of choice. Search the available options and find out which airline best fits your needs and budget.
If I'm not able to travel, can I cancel my Santa Lucia holiday package?
Yes, you can. We realise life doesn't always go to plan, so we're here to help if you have to make changes to your Santa Lucia holiday package. It may be possible to cancel or amend your itinerary at no cost if you've booked in the last 24 hours. Your airline, hotel or car rental company may charge you a fee if your booking was made more than 24 hours ago. Visit our Customer Service Portal for further information. Also, check your itinerary for the nitty-gritty on change fees.

Stay near popular Santa Lucia attractions

Porto Piccolo

8.8/10 (189 reviews)
Explore the waterfront in Syracuse with a trip to Porto Piccolo. Wander the seaside in this culturally rich area.
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