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Our top choices for Santo Domingo hotels

Casa De Sierra Azul

Casa De Sierra Azul
3.5 star property
16.2 km from Santo Domingo
9.2 out of 10, Wonderful, (898)
"Hospitality was the best. Great location with a lot of shops and Zocalo at walkable distance. rooms were beautiful and comfortable "
United States
Brian
Casa De Sierra Azul

Majagua Hotel Boutique Adults Only

Majagua Hotel Boutique Adults Only
3.5 star property
15.8 km from Santo Domingo
9.0 out of 10, Wonderful, (87)
"We liked it a lot, I recommend!"
Canada
Maria Eulalia
The price is 3.704.490 ₫
4.408.343 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Majagua Hotel Boutique Adults Only

City Centro by Marriott Oaxaca

City Centro by Marriott Oaxaca
3.5 star property
15.9 km from Santo Domingo
9.0 out of 10, Wonderful, (758)
"I absolutely loved my stay at city centro. It’s beautiful, the room was perfect, the staff & amenities were 10/10 and the bed was comfortable. I will definitely be back & will recommend this hotel to all my friends and family when visiting Oaxaca. "
United States
Armando Daniel
The price is 3.794.571 ₫
4.515.539 ₫ total
includes taxes & fees
16 Dec - 17 Dec
City Centro by Marriott Oaxaca

Hotel Azul Oaxaca

Hotel Azul Oaxaca
16 km from Santo Domingo
9.2 out of 10, Wonderful, (147)
"Staff great restaurants and cafes great and room was great. "
United States
Ryan
The price is 8.679.376 ₫
10.328.457 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Hotel Azul Oaxaca

Casa Vertiz

Casa Vertiz
3.0 star property
15.8 km from Santo Domingo
9.0 out of 10, Wonderful, (411)
"Casa Vertiz was an excellent choice for us, we found clean rooms, great service, good food, the people was very friendly and helpful. I will definitely will stay here next time I visit Oaxaca. "
United States
Rocio
The price is 3.179.883 ₫
3.784.060 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Casa Vertiz

Casa Olié

Casa Olié
3.5 star property
16.2 km from Santo Domingo
9.6 out of 10, Exceptional, (76)
"Great and easy. Got sent details on how to get to the hotel. Easy as!"
Australia
Janina
The price is 3.120.953 ₫
3.713.935 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Casa Olié

Hotel Sin Nombre

Hotel Sin Nombre
4.0 star property
16 km from Santo Domingo
8.6 out of 10, Excellent, (88)
"I loved this hotel! Perfect location. Rooms are clean and staff is friendly. "
United States
Vanessa
The price is 6.503.854 ₫
8.389.972 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Hotel Sin Nombre

Flavia Hotel

Flavia Hotel
3.0 star property
12.4 km from Santo Domingo
9.0 out of 10, Wonderful, (84)
"Todo excelente "
Mexico
Montserrat
The price is 5.490.683 ₫
6.533.913 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
Flavia Hotel

Casa de Adobe Gallery & Luxury Boutique

Casa de Adobe Gallery & Luxury Boutique
4.0 star property
13.7 km from Santo Domingo
9.0 out of 10, Wonderful, (177)
"Hotel was very clean, great food, and very friendly staff! "
United States
ANGELICA
Casa de Adobe Gallery & Luxury Boutique

Hotel CasAntica

Hotel CasAntica
3.5 star property
15.8 km from Santo Domingo
8.4 out of 10, Very good, (1001)
"Great place to stay in "
United States
Isabel
The price is 2.997.868 ₫
3.567.463 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Hotel CasAntica

Hotel Los Amantes

Hotel Los Amantes
3.0 star property
15.6 km from Santo Domingo
8.4 out of 10, Very good, (227)
"The area was really noisy up to midnight "
United States
Guadalupe
The price is 5.667.842 ₫
6.744.737 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel Los Amantes

Hotel Oaxaca Real

Hotel Oaxaca Real
3.5 star property
15.7 km from Santo Domingo
8.4 out of 10, Very good, (890)
"It was very nice and the personal was very friendly."
United States
Sindia
The price is 3.429.305 ₫
4.080.873 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Hotel Oaxaca Real

Hotel Rustiko

Hotel Rustiko
3.0 star property
18.9 km from Santo Domingo
8.4 out of 10, Very good, (44)
"They have cockroaches in the room. The room wasn’t very clean."
United States
Librado
The price is 1.372.125 ₫
1.632.826 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Hotel Rustiko

Hotel Casa Conzatti

Hotel Casa Conzatti
3.0 star property
15.4 km from Santo Domingo
8.8 out of 10, Excellent, (181)
"Good location across the street from a park and walking distance to dining and shopping."
United States
Ellen
The price is 2.394.811 ₫
2.849.825 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Hotel Casa Conzatti

Hotel De La Parra

Hotel De La Parra
4.0 star property
16.2 km from Santo Domingo
9.2 out of 10, Wonderful, (519)
"Nice pool area and really walkable to everything in the center of the city. "
United States
Jenna
The price is 7.277.178 ₫
8.659.840 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Hotel De La Parra

Marialicia Suites

Marialicia Suites
3.5 star property
16.6 km from Santo Domingo
9.8 out of 10, Exceptional, (205)
"We thoroughly enjoyed this modern property. Great value for money. The staff was very pleasant and helpful. Would love to stay here if we visit Oaxaca again."
United States
Kewan Qadre
The price is 3.854.135 ₫
4.794.894 ₫ total
includes taxes & fees
13 Dec - 14 Dec
Marialicia Suites

Galerias Oaxaca Suites

Galerias Oaxaca Suites
2.0 star property
12.5 km from Santo Domingo
9.4 out of 10, Exceptional, (3)
"Good suites to stay "
United States
Fortino
The price is 7.082.835 ₫
8.428.574 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
Galerias Oaxaca Suites

Becino

Becino
4.0 star property
15.7 km from Santo Domingo
10.0 out of 10, Exceptional, (2)
"La habitación muy linda, el personal muy amable."
Mexico
Patricia
The price is 7.452.847 ₫
8.868.891 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Becino

Ébano by PB - Palacio Borghese

Ébano by PB - Palacio Borghese
4.0 star property
15.5 km from Santo Domingo
9.4 out of 10, Exceptional, (469)
"Great location, very close to the center. Staff goes above and beyond to make sure you have an excellent experience."
United States
Sahana
The price is 5.329.508 ₫
6.342.114 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Ébano by PB - Palacio Borghese

Hotel Boutique Naura Centro

Hotel Boutique Naura Centro
3.5 star property
16.2 km from Santo Domingo
9.2 out of 10, Wonderful, (980)
"wonderful staff and great amenities. Delicious food in their restaurant + cafe."
United States
Edna
The price is 2.598.370 ₫
3.092.060 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
Hotel Boutique Naura Centro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Santo Domingo Hotel Reviews

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Frequently asked questions

What's it like in Santo Domingo?
Travellers will be sure to find plenty to entertain them in Villa de Etla's Santo Domingo neighbourhood.
If I need to cancel my hotel reservation in Santo Domingo, will I receive a refund?
Yes! You'll find that most hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to view the best deals available in Santo Domingo.
What is there to do in this Villa de Etla neighbourhood?
Places you might want to visit in the area around Santo Domingo include Parroquia de San Pedro y San Pablo Etla and Balneario Las Brisas. You could also plan a stop at San Pablo Trailhead when you're sightseeing around the area.