
Find hotels in Seneca, SC from 1.692.248 ₫
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Our top choices for Seneca hotels




1. Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ Area



2. Lakeside Lodge Clemson
Lakeside Lodge Clemson



3. Tru by Hilton Seneca Clemson
Tru by Hilton Seneca Clemson



4. Hampton Inn & Suites Seneca-Clemson Area
Hampton Inn & Suites Seneca-Clemson Area



5. Best Western Seneca-Clemson
Best Western Seneca-Clemson



6. Quality Inn Seneca US-123
Quality Inn Seneca US-123



7. Days Inn by Wyndham Seneca / Clemson Area
Days Inn by Wyndham Seneca / Clemson Area



8. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy



9. Clemson University's James F. Martin Inn
Clemson University's James F. Martin Inn



10. The Abernathy of Clemson
The Abernathy of Clemson



11. The Shepherd Hotel Downtown Clemson
The Shepherd Hotel Downtown Clemson



12. Hampton Inn Clemson-University Area
Hampton Inn Clemson-University Area



13. The Inn at Patrick Square
The Inn at Patrick Square



14. Comfort Inn & Suites Clemson - University Area
Comfort Inn & Suites Clemson - University Area



15. Holiday Inn Express & Suites Clemson by IHG
Holiday Inn Express & Suites Clemson by IHG



16. Inn @ Clemson
Inn @ Clemson



17. Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference Center



18. Courtyard Marriott Clemson
Courtyard Marriott Clemson



19. Rodeway Inn & Suites Walhalla
Rodeway Inn & Suites Walhalla



20. Liberty Hall Bed and Breakfast
Liberty Hall Bed and BreakfastHoliday Rentals in Seneca




Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy"Me and my family had a great time"




8 Mi to Clemson: Peaceful Family Home w/ Yard
8 Mi to Clemson: Peaceful Family Home w/ Yard"The place was all out perfect the owner was polite and perfect. It was a very peaceful place to stay thank you so much."




Home w/ Lake Keowee Access: Sleeps 7, Coffee Bar
Home w/ Lake Keowee Access: Sleeps 7, Coffee Bar"The best, perfect "




Screened Patio & Yard: Clemson Weekends/lakes Stay
Screened Patio & Yard: Clemson Weekends/lakes Stay"The townhome was perfect for our son’s graduation weekend. Very easy ride to Clemson campus. The kitchen was well appointed with what u need to cook. The place was clean and well cared for. Hosts were very helpful and responded quickly to questions. Thanks for a great stay!"




Waterfront Seneca Cabin ~ 4 Mi to Boat Launch!
Waterfront Seneca Cabin ~ 4 Mi to Boat Launch!"Beautiful and quaint cabin! Highly recommend, great view of the lake."




Lake Hartwell Home w/ Dock < 10 Miles to Clemson!
Lake Hartwell Home w/ Dock < 10 Miles to Clemson!"The home was adorable and served its purpose for our trip. We will definitely book again."
Where to stay in Seneca


Downtown
City centre Seneca captures the essence of small-town Southern charm with its well-preserved railway heritage and historic brick buildings. Tree-lined streets lead to charming shops and local eateries housed in structures dating back to the 1800s. Ram Cat Alley's colourful murals tell stories of local history while the old courthouse square hosts community gatherings. This walkable district offers a peaceful retreat from big city life. Visitors can browse antique stores for railway memorabilia, sample authentic Southern comfort food, or explore the cultural exhibits at the Bertha Lee Strickland Museum. The nearby Lake Keowee provides outdoor recreation just minutes away.

Serenity Bay
Serenity Bay offers a peaceful retreat within Saxony Forest's coastal embrace. The quiet residential streets wind through mature trees, creating a tranquil atmosphere away from tourist crowds. Nature lovers can explore nearby Lake Keowee or enjoy the neighborhood's forest trails. The area perfectly balances woodland serenity with beach proximity. Visitors should plan for self-contained holiday rentals rather than hotels. While dining options are limited within the area, the natural surroundings provide ideal conditions for relaxation and outdoor recreation.

Pine Ridge Point
Lake Keowee's serene waters lap against the shores of Pine Ridge Point, a tranquil residential haven in Seneca. Private docks stretch into crystal-clear waters where boats gently bob. Towering pines create natural privacy between lakefront homes. Visitors enjoy peaceful mornings watching mist rise over the water. This area offers an authentic lakeside living experience without tourist crowds. Holiday rentals range from cosy cabins to luxury estates with private boat slips. Days revolve around swimming, fishing, and water sports on Lake Keowee. Nature trails wind through mature forests for hiking and birdwatching.
Indian Oaks
Indian Oaks offers a tranquil retreat in suburban Seneca where mature oak trees create natural canopies over peaceful residential streets. This family-oriented community provides an authentic glimpse into American suburban living without tourist crowds. Landscaped yards and community green spaces showcase South Carolina's native beauty. Visitors can enjoy quiet morning walks on spacious pavements while listening to birdsong. Lake Keowee lies just beyond the area boundaries for those seeking water activities. With minimal commercial presence, Indian Oaks delivers a genuinely restful experience away from urban bustle.
Stay near popular Seneca attractions

High Falls County Park

Blue Ridge Field
Friendship Recreation Area
Toy Train Park
Highpointe Field
Oconee County Library Seneca Branch
South Cove Park
World of Energy
Learn more about Seneca
Nestled along Lake Keowee's shoreline, this charming town offers spectacular waterfront activities from kayaking to fishing at South Cove County Park. Nearby Stumphouse Tunnel and Issaqueena Falls provide fascinating historical exploration and refreshing natural beauty, especially during summer's humid afternoons.
See all hotels in Seneca
Top Seneca Hotel Reviews
The Abernathy of Clemson
"Very conveniently located to Clemson and well maintained. We enjoyed having an afternoon beverage at the bar and grabbing a quick bite to eat in the morning. Hallways were quiet and I appreciated the bathroom amenities and robes too. I would definitely recommend staying here."
Comfort Inn & Suites Clemson - University Area
"room was clean and comfortable. bathywas a bit on the small size but doable. breakfast was normal and ok. staff was very friendly and accommodating."
Quality Inn Seneca US-123
"Second time here! Staff great! This time my room smelled of smoke as a non smoking room! Comforter was clean but from a smoking room and smelled despite it being clean!"
Inn @ Clemson
"I didn't get up for the breakfast, but the room was clean. Everything you should expect. The price was lower than others in the area. I was pleasantly surprised."
Woodspring Suites Anderson North I-85
"Everything was great only thing I would make note of is the shower curtain had mold on it."
Horizon Inn & Suites
"The pretty lady at the front desk is absolutely fabulous."
The Shepherd Hotel Downtown Clemson
"It was a lovely from beginning to end. The staff is amazing."
Hampton Inn & Suites Seneca-Clemson Area
"Great place to stay when visiting Clemson!"
Best Western Seneca-Clemson
"Stayed @ hotel for a football weekend. Hotel was awesome...one of the cleanest I've ever stayed in regardless of hotels' star ratings. The only reason I gave it 4 stars was two things....#1 The bed was a bit too hard for me. I'm used to softer mattresses, but these were a little too hard for me. #2....There was one staff person that was just not very friendly @ the front desk for part of my stay. She wasn't rude & she fulfilled my requests, but she just was not as outgoing as other team members & that stuck out to me. Would I stay at this hotel again? Absolutely...it's been many yrs since I've stayed in a BW...I tend to stay in the upper crust hotels, so I was very pleasantly surprised! Great job Best Western!!"
More cheap stays in Seneca

Days Inn by Wyndham Anderson

Horizon Inn & Suites

Quality Inn Seneca US-123

Best Western Plus Clemson Hotel & Conference Center

Comfort Inn & Suites Clemson - University Area

Lakeside Lodge Clemson
Hotels in Seneca with star rating

3 Star Hotels

2 Star Hotels
