Find hotels in Seneca, SC from 1.529.410 ₫

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Our top choices for Seneca hotels

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very good, (692 reviews)
"Room was very clean, the grounds was in well taken care of, was safe. Overall a good place to stay."
United States
Billy
The price is 2.165.670 ₫
2.545.964 ₫ total
includes taxes & fees
25 Apr - 26 Apr
Quality Inn Seneca Clemson Area US-123

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1,009 reviews)
"Great place and location, great mattress, "
United States
Jeffrey
The price is 2.870.188 ₫
3.562.983 ₫ total
includes taxes & fees
14 Apr - 15 Apr
Lakeside Lodge Clemson

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
Seneca
9.4 out of 10, Exceptional, (214 reviews)
"Hotel and room were super clean. Hotel is fairly new and it shows. Nice view of Lake Keowee. Breakfast was quite good & excellent coffee. Would definitely stay there again. "
United States
Matthew
The price is 3.397.215 ₫
3.736.935 ₫ total
includes taxes & fees
12 Apr - 13 Apr
Fairfield Inn & Suites Seneca Clemson Univ Area

Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
Seneca
8.4 out of 10, Very good, (653 reviews)
"Room was clean and staff was very efficient. "
United States
Judith
The price is 2.350.131 ₫
2.585.144 ₫ total
includes taxes & fees
19 Apr - 20 Apr
Best Western Seneca-Clemson

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (68 reviews)
"Excellent stay."
United States
Beonca
The price is 2.448.876 ₫
3.852.372 ₫ total
includes taxes & fees
10 May - 11 May
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
Seneca
9.2 out of 10, Wonderful, (822 reviews)
"Nice clean hotel with several food options available nearby."
United States
kelsey
The price is 3.023.258 ₫
3.325.584 ₫ total
includes taxes & fees
22 Apr - 23 Apr
Tru by Hilton Seneca Clemson

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
Seneca
9.2 out of 10, Wonderful, (692 reviews)
"Everything was great. "
United States
Wendy
The price is 3.246.209 ₫
3.570.883 ₫ total
includes taxes & fees
19 Apr - 20 Apr
Hampton Inn & Suites Seneca-Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
Seneca
6.8 out of 10, (735 reviews)
"Our stay was ok..the bathroom was in need of renovation "
United States
clyde
The price is 1.835.604 ₫
2.019.165 ₫ total
includes taxes & fees
12 Apr - 13 Apr
Days Inn by Wyndham Seneca / Clemson Area

8 Mi to Clemson: Peaceful Family Home w/ Yard

8 Mi to Clemson: Peaceful Family Home w/ Yard
3.0 star property
Seneca
10.0 out of 10, Exceptional, (1 review)
"The place was all out perfect the owner was polite and perfect. It was a very peaceful place to stay thank you so much."
United States
Jason
The price is 3.765.905 ₫
10.255.376 ₫ total
includes taxes & fees
3 May - 4 May
8 Mi to Clemson: Peaceful Family Home w/ Yard

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson
2.0 star property
Anderson
8.0 out of 10, Very good, (1,007 reviews)
"Awesome place "
United States
Tramaness
The price is 1.544.548 ₫
1.714.447 ₫ total
includes taxes & fees
20 Apr - 21 Apr
Days Inn by Wyndham Anderson

Baymont by Wyndham Easley/Greenville

Baymont by Wyndham Easley/Greenville
2.5 star property
Easley
7.4 out of 10, Good, (798 reviews)
"Fantastic place and staff most accommodating "
United States
Walter
The price is 1.659.105 ₫
1.841.870 ₫ total
includes taxes & fees
10 Apr - 11 Apr
Baymont by Wyndham Easley/Greenville

Quality Inn Clemson near University

Quality Inn Clemson near University
2.5 star property
Anderson
7.0 out of 10, Good, (910 reviews)
"Staff was great and our beds were very comfortable!"
United States
Laurie
The price is 1.377.847 ₫
1.529.410 ₫ total
includes taxes & fees
26 Apr - 27 Apr
Quality Inn Clemson near University

Quality Inn & Suites Easley - Greenville

Quality Inn & Suites Easley - Greenville
2.5 star property
Easley
7.0 out of 10, Good, (420 reviews)
"Clean room Friendly Staff"
United States
Andrina
The price is 1.474.592 ₫
1.636.798 ₫ total
includes taxes & fees
23 Apr - 24 Apr
Quality Inn & Suites Easley - Greenville

Microtel Inn & Suites by Wyndham Anderson/Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson
2.0 star property
Anderson
8.2 out of 10, Very good, (1,000 reviews)
"Great place to stay. Great foods around. Excellent customer service."
United States
Lucero
The price is 2.104.430 ₫
2.335.918 ₫ total
includes taxes & fees
15 Apr - 16 Apr
Microtel Inn & Suites by Wyndham Anderson/Clemson

Hampton Inn Anderson/ Alliance Business Park

Hampton Inn Anderson/ Alliance Business Park
2.5 star property
Anderson
9.2 out of 10, Wonderful, (832 reviews)
"Staff were so helpful , place was clean and food spots near by"
United States
osiry
The price is 2.989.549 ₫
3.318.400 ₫ total
includes taxes & fees
26 Apr - 27 Apr
Hampton Inn Anderson/ Alliance Business Park

Hampton Inn Hartwell

Hampton Inn Hartwell
2.5 star property
Hartwell
9.0 out of 10, Wonderful, (365 reviews)
"Great stay"
United States
Annmargaret
The price is 3.021.415 ₫
3.606.302 ₫ total
includes taxes & fees
17 Apr - 18 Apr
Hampton Inn Hartwell

Hilton Garden Inn Anderson

Hilton Garden Inn Anderson
3.0 star property
Anderson
9.0 out of 10, Wonderful, (711 reviews)
"Great stay. Clean room, quiet stay, convenient location."
United States
Scott
The price is 2.615.558 ₫
2.903.268 ₫ total
includes taxes & fees
10 May - 11 May
Hilton Garden Inn Anderson

Fairfield Inn & Suites by Marriott Anderson Clemson

Fairfield Inn & Suites by Marriott Anderson Clemson
3.0 star property
Anderson
9.0 out of 10, Wonderful, (569 reviews)
"Staff at the desk was absolutely fantastic! "
United States
Brooke A
The price is 2.238.475 ₫
2.484.708 ₫ total
includes taxes & fees
20 Apr - 21 Apr
Fairfield Inn & Suites by Marriott Anderson Clemson

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
Clemson
8.2 out of 10, Very good, (1,002 reviews)
"Easy check in / clean room / nice staff& good breakfast …well done "
United States
HANS
The price is 2.775.393 ₫
3.080.687 ₫ total
includes taxes & fees
10 May - 11 May
Comfort Inn & Suites Clemson - University Area

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
2.5 star property
Anderson
9.0 out of 10, Wonderful, (607 reviews)
"Clean rooms, friendly staff, great breakfast options!"
United States
Lauren
The price is 2.791.192 ₫
3.098.223 ₫ total
includes taxes & fees
10 May - 11 May
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Seneca

Find the best Seneca areas for the activities you enjoy most. Learn more about Seneca
Learn more about Seneca

Downtown

City centre Seneca captures the essence of small-town Southern charm with its well-preserved railway heritage and historic brick buildings. Tree-lined streets lead to charming shops and local eateries housed in structures dating back to the 1800s. Ram Cat Alley's colourful murals tell stories of local history while the old courthouse square hosts community gatherings. This walkable district offers a peaceful retreat from big city life. Visitors can browse antique stores for railway memorabilia, sample authentic Southern comfort food, or explore the cultural exhibits at the Bertha Lee Strickland Museum. The nearby Lake Keowee provides outdoor recreation just minutes away.

Serenity Bay

Serenity Bay offers a peaceful retreat within Saxony Forest's coastal embrace. The quiet residential streets wind through mature trees, creating a tranquil atmosphere away from tourist crowds. Nature lovers can explore nearby Lake Keowee or enjoy the neighborhood's forest trails. The area perfectly balances woodland serenity with beach proximity. Visitors should plan for self-contained holiday rentals rather than hotels. While dining options are limited within the area, the natural surroundings provide ideal conditions for relaxation and outdoor recreation.

Pine Ridge Point

Lake Keowee's serene waters lap against the shores of Pine Ridge Point, a tranquil residential haven in Seneca. Private docks stretch into crystal-clear waters where boats gently bob. Towering pines create natural privacy between lakefront homes. Visitors enjoy peaceful mornings watching mist rise over the water. This area offers an authentic lakeside living experience without tourist crowds. Holiday rentals range from cosy cabins to luxury estates with private boat slips. Days revolve around swimming, fishing, and water sports on Lake Keowee. Nature trails wind through mature forests for hiking and birdwatching.

Indian Oaks

Indian Oaks offers a tranquil retreat in suburban Seneca where mature oak trees create natural canopies over peaceful residential streets. This family-oriented community provides an authentic glimpse into American suburban living without tourist crowds. Landscaped yards and community green spaces showcase South Carolina's native beauty. Visitors can enjoy quiet morning walks on spacious pavements while listening to birdsong. Lake Keowee lies just beyond the area boundaries for those seeking water activities. With minimal commercial presence, Indian Oaks delivers a genuinely restful experience away from urban bustle.

Stay near popular Seneca attractions

Learn more about Seneca

Nestled along Lake Keowee's shoreline, this charming town offers spectacular waterfront activities from kayaking to fishing at South Cove County Park. Nearby Stumphouse Tunnel and Issaqueena Falls provide fascinating historical exploration and refreshing natural beauty, especially during summer's humid afternoons.

Lake Keowee South Carolina

Top Seneca Hotel Reviews

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Frequently asked questions

What's the seasonal weather in Seneca?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 8°C. Average annual precipitation for Seneca is 1565 mm.