Search Hotels in Serin, Lyon

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
5 Dec - 6 Dec
Tomorrow
6 Dec - 7 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

Filter by

Guest rating
Guest rating
Star rating

Top Trending Hotels Near Serin, Lyon

Lunch and dinner served
Hotel Lyon Métropole

Hotel Lyon Métropole

4.0 star property
Serin
8.6 out of 10, Excellent, (1000)
"It is worth paying for spa/pool. It is amazing! Nice clean hotel and polite staff"
Norway
Anonymous traveller
The price is 3.600.986 ₫
4.136.728 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel Lyon Métropole
Exterior
Campanile PRIME - Lyon Centre Gare Part Dieu

Campanile PRIME - Lyon Centre Gare Part Dieu

3.0 star property
4.2 km from Serin
9.0 out of 10, Wonderful, (1183)
"Nice place to stay."
United States
Yuanmei
The price is 1.723.122 ₫
2.010.514 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Campanile PRIME - Lyon Centre Gare Part Dieu
Junior Suite | 10 bedrooms, desk, blackout curtains, soundproofing
Hotel Vaubecour

Hotel Vaubecour

2.0 star property
2nd Arrondissement, 3 km from Serin
9.2 out of 10, Wonderful, (323)
"This hotel is located in a great area with easy access to the train station, metro stations, and lots of shopping and restaurants. The staff is very nice and helpful. Would definitely stay here again!"
Canada
Nicholas
The price is 2.623.896 ₫
2.953.994 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Hotel Vaubecour
Daily buffet breakfast (EUR 10 per person)
Premiere Classe Lyon Centre - Gare Part Dieu

Premiere Classe Lyon Centre - Gare Part Dieu

2.0 star property
Part Dieu - Bir Hakeim, 4.2 km from Serin
8.0 out of 10, Very good, (1000)
"Excellent stay , clean tiny hotel , excellent service , thank you"
Canada
Dorin
The price is 1.559.873 ₫
1.783.415 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Premiere Classe Lyon Centre - Gare Part Dieu
Front of property
Hotel Silky by HappyCulture

Hotel Silky by HappyCulture

4.0 star property
Les Cordeliers, 2.3 km from Serin
8.8 out of 10, Excellent, (969)
"Amazing location and hotel. Perfect for seeing the sites and coming back and feeling welcomed by the staff. Great breakfast too!"
Canada
Cameron
The price is 2.769.303 ₫
3.222.238 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel Silky by HappyCulture
Premium Double Room | In-room safe, individually decorated, individually furnished, desk
Globe et Cecil Hôtel

Globe et Cecil Hôtel

4.0 star property
Bellecour - Hôtel Dieu, 2.7 km from Serin
8.4 out of 10, Very good, (525)
"Very nice stay, loved the location and the hotel! "
Sweden
Sandra
The price is 3.575.807 ₫
4.109.184 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Globe et Cecil Hôtel
Exterior
Mercure Lyon Centre Château Perrache

Mercure Lyon Centre Château Perrache

4.0 star property
Perrache, 3.4 km from Serin
8.2 out of 10, Very good, (818)
"Hotel is dated and could use remodeling. Staff was good."
United States
Rene
The price is 2.622.082 ₫
3.059.934 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Mercure Lyon Centre Château Perrache
Triple Room | Desk, soundproofing, free WiFi, bed sheets
Hotel du Simplon

Hotel du Simplon

3.0 star property
Carnot - Gailleton, 3.5 km from Serin
8.4 out of 10, Very good, (1000)
"Great location and great value!"
United States
Cyrus
The price is 2.471.897 ₫
2.833.936 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Hotel du Simplon
Exterior
Le Phenix Hotel

Le Phenix Hotel

4.0 star property
Old Lyon, 1.7 km from Serin
9.2 out of 10, Wonderful, (1000)
"Fantastic location with excellent rooms"
United States
Hudson
The price is 3.126.259 ₫
3.614.497 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Le Phenix Hotel
View from property
Fourvière Hôtel Lyon

Fourvière Hôtel Lyon

4.0 star property
Fourvière, 2.3 km from Serin
9.2 out of 10, Wonderful, (1003)
"This property was excellent "
United States
Ed
Fourvière Hôtel Lyon
Front of property
B&B HOTEL LYON Centre Perrache

B&B HOTEL LYON Centre Perrache

3.0 star property
7th Arrondissement, 3.8 km from Serin
8.2 out of 10, Very good, (517)
"Convenient location when coming or going from a river cruise on the Rhone."
Canada
DERYK
The price is 1.833.503 ₫
2.131.666 ₫ total
includes taxes & fees
21 Dec - 22 Dec
B&B HOTEL LYON Centre Perrache
Lobby
Campanile Lyon Centre-Berges du Rhône

Campanile Lyon Centre-Berges du Rhône

3.0 star property
3rd Arrondissement, 3.2 km from Serin
7.8 out of 10, Good, (1000)
"Good stay for one night in Lyon. Good basic hotel. "
United Kingdom
Olivia
The price is 1.566.475 ₫
1.838.203 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Campanile Lyon Centre-Berges du Rhône
Restaurant
Hôtel des Célestins

Hôtel des Célestins

3.0 star property
Bellecour - Hôtel Dieu, 2.6 km from Serin
9.0 out of 10, Wonderful, (391)
"This is the perfect location and a beautiful smaller hotel, highly recommend."
United States
Steven
The price is 2.713.364 ₫
3.099.543 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Hôtel des Célestins
Exterior
ibis Lyon Centre Perrache

ibis Lyon Centre Perrache

3.0 star property
Perrache, 3.6 km from Serin
8.8 out of 10, Excellent, (929)
"Clean with comfortable bed and good shower. In walking distance of places to visit. Near station."
United Kingdom
alan
The price is 2.111.511 ₫
2.437.505 ₫ total
includes taxes & fees
26 Dec - 27 Dec
ibis Lyon Centre Perrache
Exterior
Hôtel Taggât

Hôtel Taggât

2.0 star property
2.6 km from Serin
8.2 out of 10, Very good, (399)
"Friendly staff, cool location!"
United States
Matthieu
Hôtel Taggât
Garden
Appart'hôtel Odalys City - Lyon Centre Confluence

Appart'hôtel Odalys City - Lyon Centre Confluence

3.9 km from Serin
8.0 out of 10, Very good, (793)
"The property was good and well maintained but the homeless people camped nearby felt unsafe."
United Kingdom
Elaine
The price is 1.831.242 ₫
2.115.084 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Appart'hôtel Odalys City - Lyon Centre Confluence
City view from property
Novotel Lyon Gerland Musée des Confluences

Novotel Lyon Gerland Musée des Confluences

4.0 star property
5.3 km from Serin
8.2 out of 10, Very good, (1001)
"Great location for trip through France "
United Kingdom
Colin
The price is 2.270.451 ₫
2.673.501 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Novotel Lyon Gerland Musée des Confluences
Restaurant
Bikube Lyon

Bikube Lyon

4.0 star property
3rd Arrondissement, 5 km from Serin
9.0 out of 10, Wonderful, (179)
"Everything was great! Staff were alway friendly and helpful! Room was immaculate. Shared living space was cool. Close to Metro. Highly recommend!"
United States
Kathleen
The price is 2.255.108 ₫
2.656.262 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Bikube Lyon
Classic Room with balcony including self-service snacks and drinks at the Club | Premium bedding, in-room safe, desk, soundproofing
OKKO Hotels Lyon Centre

OKKO Hotels Lyon Centre

4.0 star property
2.6 km from Serin
9.0 out of 10, Wonderful, (1000)
"Fantastic hotel, welcoming staff. "
Canada
Carol
The price is 2.903.188 ₫
3.369.150 ₫ total
includes taxes & fees
14 Dec - 15 Dec
OKKO Hotels Lyon Centre
Comfort Room, 1 Queen Bed | Premium bedding, desk, iron/ironing board, free WiFi
Hôtel Victoria Lyon Perrache Confluence

Hôtel Victoria Lyon Perrache Confluence

2.0 star property
Perrache, 3.6 km from Serin
8.4 out of 10, Very good, (560)
"Very good place to stay, clean, friendly guys on the reception"
Mexico
Jakub
The price is 1.898.239 ₫
2.155.618 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Hôtel Victoria Lyon Perrache Confluence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Serin

Find the best Serin areas for the activities you enjoy most.

Lyon City Centre

Gourmet restaurants interesting history and top sights from Bellecour Square to Hôtel-Dieu – discover Lyon City Centre, a destination also famous for its shopping.

Lyon showing a city, a river or creek and a statue or sculpture

Old Lyon

If you're spending time in Old Lyon, you might enjoy attractions like Lyon Cathedral and Palais de Justice de Lyon. You might also enjoy the neighbourhood's ample dining options before hopping on the metro at Vieux Lyon Station to see more of the city.

Bellecour Square which includes a statue or sculpture, a river or creek and a bridge

Bellecour - Hôtel Dieu

While you're in Bellecour - Hôtel Dieu, take in top sights like Bellecour Square and jump on the metro at Bellecour Station to see more of the city.

3rd Arrondissement

Noted for its shopping and river views, there's plenty to explore in 3rd Arrondissement. Top attractions like Part Dieu Mall and Halles de Lyon - Paul Bocuse are major draws, and you can hop on the metro at Dauphine - Lacassagne Tram Stop or Archives Départementales Tram Stop to see more of the city.

Lyon showing a church or cathedral and heritage architecture

Les Cordeliers

Take time in Les Cordeliers to visit attractions like Museum of Fine Arts of Lyon and Place des Terreaux. You might also appreciate the abundant dining options, and you can hop on the metro at Cordeliers Bourse Station to see more of the city.

Top Serin Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

What is Serin like?
You'll be sure to have fun exploring Lyon's Serin neighbourhood. Consider a visit to Historic Site of Lyon as part of your Serin travel plans.
If I need to cancel my hotel reservation in Serin, will I receive a refund?
Yes! Most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Add dates, click "Search", then you can use the "fully refundable" filter to review the best deals in Serin.
What is there to do in this Lyon neighbourhood?
Historic Site of Lyon is an attraction you might want to check out while you're in Serin. While you're out sightseeing, Mur des Canuts and Le Jardin Des Chartreux are a couple of additional sights to visit in Lyon.