South San Diego Holidays
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Photo by Elizabeth Bagnas
Where to stay in South San Diego
Find the best South San Diego areas and neighborhoods for the activities you enjoy most. Learn more about South San Diego
Otay Mesa West
Even though there aren't top sights in Otay Mesa West, you can explore the larger area and take in top sights like San Ysidro Border Crossing. Jump on the metro at Iris Avenue Trolley Station to see more of the city.
Top hotels in South San Diego
Holiday Inn Express San Diego South - Chula Vista by IHG
632 E Street Chula Vista CA
Fully refundableReserve now, pay when you stay
The price is 4.312.710 ₫ per night from 28 Jun to 29 Jun
4.312.710 ₫
4.743.981 ₫ total
28 Jun - 29 Jun
includes taxes & fees
9.4/10 Exceptional! (1,242 reviews)
"Staff member Edgar has an attitude and I do not want to interact with him. Makes gestures , does not look at you in the eye, First interaction was going ok then he caught himself about to say something when I asked him a question… then second time he was just looking away and annoyed but Naomi came ..."
Reviewed on 16 Jun 2026
Manchester Grand Hyatt San Diego
1 Market Pl San Diego CA
Fully refundableReserve now, pay when you stay
The price is 6.811.182 ₫ per night from 1 Jul to 2 Jul
6.811.182 ₫
9.330.267 ₫ total
1 Jul - 2 Jul
includes taxes & fees
9/10 Wonderful! (2,801 reviews)
"We got upgraded to a better view, but was disappointed that plumbing was backing up in the shower and sink. Staff took off the extra fee for upgrade due to complaint. The view was amazing! The pool area was dirty."
Reviewed on 17 Jun 2026
The Sofia Hotel
150 W Broadway San Diego CA
Fully refundableReserve now, pay when you stay
The price is 2.656.701 ₫ per night from 29 Jun to 30 Jun
2.656.701 ₫
3.815.310 ₫ total
29 Jun - 30 Jun
includes taxes & fees
8.6/10 Excellent! (2,245 reviews)
"Beautiful rooms. I wish they had room service, but love the new restaurant."
Reviewed on 17 Jun 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
