Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Southern Illinois hotels

Pool

1. Drury Plaza Hotel Mt. Vernon

Mount Vernon

Candy

3.402.806 ₫ total

includes taxes & fees

10 Aug - 11 Aug

Desk, laptop workspace, blackout curtains, iron/ironing board

2. Baymont by Wyndham Effingham

Effingham

Mary

2.352.697 ₫ total

includes taxes & fees

25 Jul - 26 Jul

3. Cobblestone Inn & Suites - Altamont

Altamont

William

2.806.183 ₫ total

includes taxes & fees

19 Jul - 20 Jul

4. Best Western Delta Inn

Effingham

Roger

2.802.644 ₫ total

includes taxes & fees

9 Aug - 10 Aug

5. Country Inn & Suites by Radisson, Effingham, IL

Effingham

Jennifer

2.447.389 ₫ total

includes taxes & fees

16 Aug - 17 Aug

6. Best Western Plus Parkside Inn & Suites

Olney

Brenda

3.690.021 ₫ total

includes taxes & fees

30 Jul - 31 Jul

7. Holiday Inn Express & Suites Vandalia by IHG

Vandalia

Rebecca

2.937.186 ₫ total

includes taxes & fees

2 Aug - 3 Aug

8. Super 8 by Wyndham Troy IL/St. Louis Area

Troy

Donta

2.097.762 ₫ total

includes taxes & fees

23 Jul - 24 Jul

9. Suite Dreams Hotel

Mattoon

Judd

2.792.794 ₫ total

includes taxes & fees

19 Jul - 20 Jul

10. La Quinta Inn & Suites by Wyndham Effingham

Effingham

Alexis

3.073.572 ₫ total

includes taxes & fees

16 Aug - 17 Aug

11. The Principal Hotel

Columbia

Michelle

3.286.876 ₫ total

includes taxes & fees

26 Jul - 27 Jul

Room, 2 Queen Beds, Non Smoking | Desk, laptop workspace, blackout curtains, iron/ironing board

12. Days Inn & Suites by Wyndham Casey

Casey

Karen

1.992.873 ₫ total

includes taxes & fees

20 Jul - 21 Jul

13. Holiday Inn Effingham by IHG

Effingham

Glenn

2.771.065 ₫ total

includes taxes & fees

17 Aug - 18 Aug

14. Best Western Marion Hotel

Marion

Samantha

2.815.324 ₫ total

includes taxes & fees

5 Aug - 6 Aug

15. Country Inn & Suites by Radisson, Marion, IL

Marion

Margaret

3.446.675 ₫ total

includes taxes & fees

9 Aug - 10 Aug

16. Best Western Plus MidAmerica Hotel

Mascoutah

Craig

3.409.744 ₫ total

includes taxes & fees

21 Jul - 22 Jul

17. Holiday Inn Express & Suites Effingham by IHG

Effingham

Carol

3.468.978 ₫ total

includes taxes & fees

16 Aug - 17 Aug

18. Comfort Suites Mount Vernon

Mount Vernon

Denise

3.512.389 ₫ total

includes taxes & fees

2 Aug - 3 Aug

In-room safe, desk, iron/ironing board, cots/infant beds

19. Quality Inn & Suites Vandalia near I-70 and Hwy 51

Vandalia

Jason

1.852.149 ₫ total

includes taxes & fees

2 Aug - 3 Aug

20. Best Western Heartland Inn

Mattoon

william

2.598.793 ₫ total

includes taxes & fees

29 Jul - 30 Jul

View all properties

Holiday Rentals in Southern Illinois

Cottage

Harrisburg Home w/ Private Yard + Screened Porch!

Harrisburg

"We love how accommodating, helpful and responsive Hollie and Clayton were. The rental had everything we needed and then some. Very clean, cozy and comfortable. We chose this location, because it was close to the different parks and trails we had visited. Thank you, Hollie and Clayton, for being such gracious hosts."

Holiday Home

Villa, 4 Bedrooms | Private kitchen | Coffee/tea maker, fridge, oven

Belleville Beauty - Luxury Stay For Work Or Stay For Play Either Way This Is The Perfect Property For You! 4 Bedroom Residence by RedAwning

Belleville

"Home was nice it was older but redone. Definitely a diy job and it was noticeable. Perfect for what we needed. Every comfortable. Area was okay. Not the nicest area but also not the worst. Very good for the price. Beds were comfortable and showers were nice and hot. No coffee but there was a coffee it and Keurig. "

Cottage

Peaceful Robinson Home w/ Yard, Near Golf Courses!

Robinson

Cottage

Country Home Near EIU & Lake Charleston!

Charleston

"Property was very clean and beautifully decorated in a farmhouse style. Very cozy and comfortable! Came stocked with everything you would need. We had fun at nearby Aikman Wildlife Adventure in Arcola, Kayaking in Lake Charleston, hiking in Fox Ridge State Park a visit to Amish country in Arthur, IL. The kitchen, living and dining room were very spacious! The bathroom was very tiny so if staying with 4 adults - be prepared for this. Also there was a strange odor right outside the front entry...

Cottage

Illinois Vacation Rental Home: Pets Welcome

Palestine

Cottage

Cozy Anna Home Near Southern Illinois Attractions!

Anna

"Good communication with the owners. Nice perks such as coffee, tea, and hygiene items."

Apartment

Murphysboro Retreat w/ Deck Near Kinkaid Lake!

Murphysboro

"This is a very clean and nice apartment within a very close drive to the Kinkaid boat launch. Easy to locate and can fit a car with a boat in tow no problem. This spot was also much more quiet than the campground or RV spots nearby. They have a great porch and a grill and we didn’t bring something for it which made me sad. "

Cottage

Beautiful Makanda Cabin in Shawnee National Forest

Makanda

"It was very peaceful and relaxing. "

See all holiday rentals

Save an average of 15% on thousands of hotels when you're signed in

Sign in

Sign up, it's free

Stay near popular Southern Illinois attractions

Garden of the Gods Recreation Area

9.8/10 (63 reviews)

You can take time to visit Garden of the Gods Recreation Area during your travels to Equality. Wander the parks and riverfront while you're in the area.

See properties

Learn more about Southern Illinois

Experience the family-friendly area of Southern Illinois—live music, an opera house and sights from Jefferson County Fairgrounds to King City Square Shopping Center.

See all hotels in Southern Illinois

A forested valley with autumn foliage, a rocky cliff, and a sunset.

Top Southern Illinois Hotel Reviews

Baymont by Wyndham Marion

10/10 Excellent

"No Questions all good"

Drury Inn & Suites Marion

10/10 Excellent

"The stay was perfect the customer service was over the top and found out that I got more included in my stay than I realized including dinner and breakfast the room was very clean. Very nice. Amazing stay I will stay there again and where the chain of hotels are at. And for the record, the hotels in Ohio really need to step up their game because they suck in comparison."