Photo by Ryan Watts

Find hotels in Upstate South Carolina, SC from 1.707.975 ₫

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Upstate South Carolina hotels

Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center
3.5 star property
Greenville
9.0 out of 10, Wonderful, (1000)
" The property was really great amazing clean great breakfast"
United States
Dallas
The price is 2.424.844 ₫
2.667.329 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Embassy Suites Greenville Golf Resort & Conference Center

DoubleTree by Hilton Greenville Woodruff Road

DoubleTree by Hilton Greenville Woodruff Road
3.0 star property
Greenville
9.4 out of 10, Exceptional, (1004)
"The hotel was excellent m."
United States
Brittiany
The price is 2.667.326 ₫
2.934.059 ₫ total
includes taxes & fees
21 Dec - 22 Dec
DoubleTree by Hilton Greenville Woodruff Road

ECHO Suites Extended Stay by Wyndham Spartanburg

ECHO Suites Extended Stay by Wyndham Spartanburg
2.0 star property
Spartanburg
8.2 out of 10, Very good, (289)
"Nice hotel "
United States
Kierra
The price is 1.882.818 ₫
2.131.725 ₫ total
includes taxes & fees
14 Dec - 15 Dec
ECHO Suites Extended Stay by Wyndham Spartanburg

Hyatt Place Greenville/Haywood

Hyatt Place Greenville/Haywood
3.0 star property
Greenville
7.8 out of 10, Good, (1008)
"Slightly better than your average hotel- clean, updated rooms, decent amenities, typical sub par breakfast. "
United States
Kierstin
The price is 2.129.377 ₫
2.412.459 ₫ total
includes taxes & fees
29 Dec - 30 Dec
Hyatt Place Greenville/Haywood

Quality Inn & Suites Greenville - Haywood Mall

Quality Inn & Suites Greenville - Haywood Mall
2.5 star property
Greenville
7.4 out of 10, Good, (1002)
"The room was clean and staff very courteous. Breakfast was very good pork sausage, eggs and sausage gravy, A good hot breakfast makes me a return customer."
United States
Edward or Rosemarie
The price is 1.756.242 ₫
2.010.976 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Quality Inn & Suites Greenville - Haywood Mall

Hyatt Regency Greenville

Hyatt Regency Greenville
3.5 star property
Greenville Downtown
8.6 out of 10, Excellent, (1001)
"Staff was very friendly. "
United States
Kristin
The price is 3.562.149 ₫
4.035.914 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Hyatt Regency Greenville

Drury Inn & Suites Greenville

Drury Inn & Suites Greenville
3.0 star property
Greenville
9.6 out of 10, Exceptional, (1000)
"Very nice amenities and rooms. Staff was super friendly and very helpful when needed. We will definitely stay at another Drury Inn when traveling or needing a hotel"
United States
Blair
The price is 2.925.363 ₫
3.217.926 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Drury Inn & Suites Greenville

Holiday Inn Express & Suites Greenville - Downtown by IHG

Holiday Inn Express & Suites Greenville - Downtown by IHG
2.5 star property
Greenville Downtown
8.8 out of 10, Excellent, (1002)
"Great location, very friendly staff, nice room"
United States
Coltin
The price is 2.635.700 ₫
2.899.270 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Holiday Inn Express & Suites Greenville - Downtown by IHG

Homewood Suites by Hilton Greenville Downtown

Homewood Suites by Hilton Greenville Downtown
3.0 star property
Greenville Downtown
9.6 out of 10, Exceptional, (1000)
"Great stay."
United States
Mitchell
The price is 3.143.304 ₫
3.551.933 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Homewood Suites by Hilton Greenville Downtown

Aloft Greenville Downtown

Aloft Greenville Downtown
3.0 star property
Greenville Downtown
9.0 out of 10, Wonderful, (1000)
"Perfect place to stay!"
United States
Stephanie
The price is 3.303.634 ₫
3.633.998 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Aloft Greenville Downtown

Woodspring Suites Greenville Airport

Woodspring Suites Greenville Airport
2.5 star property
Greenville
8.2 out of 10, Very good, (300)
"Clean room, friendly staff, I would definitely stay here again!"
United States
Melissa
The price is 2.082.203 ₫
2.290.423 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Woodspring Suites Greenville Airport

SpringHill Suites by Marriott Greenville Downtown

SpringHill Suites by Marriott Greenville Downtown
2.5 star property
Greenville Downtown
9.6 out of 10, Exceptional, (1000)
"Loved our stay. Comfortable in every way. Close to all the sites and Christmas fun. Great Breakfast "
United States
Matthew
The price is 3.115.616 ₫
3.427.178 ₫ total
includes taxes & fees
25 Dec - 26 Dec
SpringHill Suites by Marriott Greenville Downtown

Hotel Hartness

Hotel Hartness
4.0 star property
Greenville
9.8 out of 10, Exceptional, (624)
"Beautiful location, friendly staff"
United States
Andrew
The price is 3.990.836 ₫
5.280.329 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Hotel Hartness

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson
2.0 star property
Anderson
7.8 out of 10, Good, (1004)
"Very nice we'll stay there again"
United States
Michael
The price is 1.658.673 ₫
1.841.128 ₫ total
includes taxes & fees
13 Dec - 14 Dec
Days Inn by Wyndham Anderson

Hampton Inn & Suites Greenville-Downtown-RiverPlace

Hampton Inn & Suites Greenville-Downtown-RiverPlace
2.5 star property
Greenville Downtown
9.4 out of 10, Exceptional, (1002)
"Clean room great atmosphere and friendly staff. "
United States
Hubert
The price is 3.143.304 ₫
3.551.933 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hampton Inn & Suites Greenville-Downtown-RiverPlace

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
2.5 star property
Spartanburg
8.6 out of 10, Excellent, (861)
"The stay was great overall, room was exceptional in size and comfort. The noise from the highway was the only distraction but mainly because we do not ever have any. The staff was friendly and helpful. We would not hesitate to stay here again."
United States
Charmaine
The price is 2.557.890 ₫
2.839.256 ₫ total
includes taxes & fees
26 Dec - 27 Dec
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Home2 Suites by Hilton Greenville Downtown

Home2 Suites by Hilton Greenville Downtown
3.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (1001)
"Great shopping nearby"
United States
Jordan
The price is 2.826.864 ₫
3.109.552 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Home2 Suites by Hilton Greenville Downtown

Comfort Inn Greenville - Haywood Mall

Comfort Inn Greenville - Haywood Mall
2.5 star property
Greenville
8.0 out of 10, Very good, (1000)
"Staff was very friendly, clean rooms, only downside is I ended up being sick during my trip and had to spend some time in the room to relax, but the tv didn’t work :( "
United States
Amanda
The price is 2.135.970 ₫
2.428.677 ₫ total
includes taxes & fees
12 Dec - 13 Dec
Comfort Inn Greenville - Haywood Mall

Sleep Inn at Greenville Convention Cente

Sleep Inn at Greenville Convention Cente
2.5 star property
Greenville
8.0 out of 10, Very good, (1002)
"The room and the hotel is showing it's age. The room and hotel were clean."
United States
Marian
The price is 2.182.645 ₫
2.471.133 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Sleep Inn at Greenville Convention Cente

The Westin Poinsett Greenville

The Westin Poinsett Greenville
4.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (1004)
"Awesome place "
United States
Dominick
The price is 4.456.530 ₫
4.902.183 ₫ total
includes taxes & fees
14 Dec - 15 Dec
The Westin Poinsett Greenville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Upstate South Carolina, SC

Showing deals for:19 Dec - 21 Dec
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Southeastern United States attractions

Learn more about Upstate South Carolina

Check out the local area in Upstate South Carolina—home to attractions like Discovery Island Water Park and Heritage Park.

It is only a 1 mile hike to this beauty.  View a video about it here:  https://www.hdcarolina.com/episode/riley-moore-falls

#Waterfall
Photo by Ryan Watts
Open Photo by Ryan Watts

Top Upstate South Carolina Hotel Reviews

More cheap stays in Upstate South Carolina

Explore a world of travel with Expedia