Photo by Ryan Watts
Find hotels in Upstate South Carolina, SC from 1.927.987 ₫
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Upstate South Carolina
Check prices for these dates
Our top choices for Upstate South Carolina hotels
Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ AreaSeneca
9.4 out of 10, Exceptional, (222 reviews)
"Excellent in every way … staff, room, amenities and very comfortable bed!"
Sarah
The price is 3.398.505 ₫
3.738.354 ₫ total
includes taxes & fees
3 May - 4 May
Holiday Inn Express Gaffney by IHG
Holiday Inn Express Gaffney by IHGGaffney
8.8 out of 10, Excellent, (477 reviews)
"Very clean and staff the super kind and friendly 10/10 stay"
Kevin
The price is 2.186.967 ₫
2.383.794 ₫ total
includes taxes & fees
10 May - 11 May
Hampton Inn Gaffney
Hampton Inn GaffneyGaffney
8.8 out of 10, Excellent, (706 reviews)
"Would stay again breakfast was amazing "
Theresa
The price is 2.255.474 ₫
2.458.361 ₫ total
includes taxes & fees
31 May - 1 Jun
Carolina Camp Cedar
Carolina Camp CedarPickens
10.0 out of 10, Exceptional, (3 reviews)
"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"
Katlynn
The price is 4.452.305 ₫
7.135.281 ₫ total
includes taxes & fees
12 May - 13 May
Inn on the Square, an Ascend Collection Hotel
Inn on the Square, an Ascend Collection HotelUptown Greenwood
9.2 out of 10, Wonderful, (736 reviews)
"Friendly staff, nice facility that is centrally located."
Frederick
The price is 2.974.275 ₫
3.301.447 ₫ total
includes taxes & fees
31 May - 1 Jun
Clemson University's James F. Martin Inn
Clemson University's James F. Martin InnClemson
9.4 out of 10, Exceptional, (1,004 reviews)
"Lovely place to stay right on the lake. "
Sara
The price is 2.608.551 ₫
2.895.492 ₫ total
includes taxes & fees
11 May - 12 May
Comfort Inn & Suites Greer - Greenville
Comfort Inn & Suites Greer - GreenvilleGreer
8.6 out of 10, Excellent, (783 reviews)
"The staff was very friendly, great breakfast and the room was very clean. Great stay. "
susan
The price is 2.568.237 ₫
2.876.257 ₫ total
includes taxes & fees
10 May - 11 May
Best Western Plus Greenville I-385 Inn & Suites
Best Western Plus Greenville I-385 Inn & SuitesGreenville
9.2 out of 10, Wonderful, (1,458 reviews)
"great stay"
Gordon
The price is 2.632.529 ₫
2.895.782 ₫ total
includes taxes & fees
3 May - 4 May
Lakeside Lodge Clemson
Lakeside Lodge ClemsonSeneca
9.0 out of 10, Wonderful, (1,000 reviews)
"This place is tops! The area is great, rooms were wonderful, and amenities were amazing. Definitely plan on staying again asap!"
Valarie Tina
The price is 2.871.605 ₫
3.564.742 ₫ total
includes taxes & fees
12 May - 13 May
Tru by Hilton Seneca Clemson
Tru by Hilton Seneca ClemsonSeneca
9.2 out of 10, Wonderful, (834 reviews)
"Great location and facilities"
Brian
The price is 3.002.803 ₫
3.303.084 ₫ total
includes taxes & fees
24 May - 25 May
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.Greenville
8.8 out of 10, Excellent, (202 reviews)
"Great place to stay"
LOUIS
The price is 1.991.984 ₫
2.256.919 ₫ total
includes taxes & fees
14 May - 15 May
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
Holiday Inn Express Hotel & Suites Spartanburg-North by IHGSpartanburg
8.6 out of 10, Excellent, (907 reviews)
"Very friendly staff"
Katie
The price is 2.371.410 ₫
2.632.265 ₫ total
includes taxes & fees
10 May - 11 May
Hampton Inn & Suites Clinton - I-26
Hampton Inn & Suites Clinton - I-26Clinton
9.0 out of 10, Wonderful, (732 reviews)
"Clean room, delicious breakfast, nice pool area"
Priscilla
The price is 3.003.259 ₫
3.363.650 ₫ total
includes taxes & fees
25 May - 26 May
Embassy Suites Greenville Golf Resort & Conference Center
Embassy Suites Greenville Golf Resort & Conference CenterGreenville
9.0 out of 10, Wonderful, (1,170 reviews)
"I have stayed here twice now and absolutely love it!! It has a great workspace and the room is spacious. The breakfast is excellent! "
Amy
The price is 2.889.168 ₫
3.178.086 ₫ total
includes taxes & fees
25 May - 26 May
Quality Inn Seneca Clemson Area US-123
Quality Inn Seneca Clemson Area US-123Downtown
8.0 out of 10, Very good, (696 reviews)
"Very pleasant and helpful staff. Comfortable room though fairly small."
William
The price is 2.282.078 ₫
2.677.556 ₫ total
includes taxes & fees
25 May - 26 May
Hampton Inn Greer Greenville, SC
Hampton Inn Greer Greenville, SCGreer
9.6 out of 10, Exceptional, (452 reviews)
"great service all around."
Alberto
The price is 3.561.067 ₫
3.881.471 ₫ total
includes taxes & fees
25 May - 26 May
Holiday Inn Anderson by IHG
Holiday Inn Anderson by IHGAnderson
8.8 out of 10, Excellent, (724 reviews)
"Great hotel in all regards"
Dan
The price is 2.897.950 ₫
3.216.726 ₫ total
includes taxes & fees
28 May - 29 May
The Inn at Patrick Square
The Inn at Patrick SquareClemson
9.8 out of 10, Exceptional, (842 reviews)
"Very nice hotel - very clean, beautiful decor."
Elizabeth
The price is 4.188.855 ₫
4.649.630 ₫ total
includes taxes & fees
4 May - 5 May
Microtel Inn & Suites by Wyndham Anderson/Clemson
Microtel Inn & Suites by Wyndham Anderson/ClemsonAnderson
8.2 out of 10, Very good, (1,001 reviews)
"Front desk staff were very friendly. We had a welcoming and quiet 1 night stay."
Nicole
The price is 2.127.682 ₫
2.361.728 ₫ total
includes taxes & fees
11 May - 12 May
Tru by Hilton Spartanburg
Tru by Hilton SpartanburgSpartanburg
9.2 out of 10, Wonderful, (888 reviews)
"Clean room , friendly staff , great location "
Gerad
The price is 2.665.201 ₫
2.958.373 ₫ total
includes taxes & fees
11 May - 12 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Rentals in Upstate South Carolina
Cabin
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott BonvoySeneca
9.8 out of 10, Exceptional, (71 reviews)
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Southeastern United States attractions
Learn more about Upstate South Carolina
Check out the local area in Upstate South Carolina—home to attractions like Discovery Island Water Park and Heritage Park.
Photo by Ryan Watts
Open Photo by Ryan Watts
Top Upstate South Carolina Hotel Reviews
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
8/10 Good
More cheap stays in Upstate South Carolina
Sleep Inn Spartanburg Southwest
501 South Blackstock Rd Spartanburg SC
The price is 1.736.926 ₫ per night from 26 May to 27 May
1.736.926 ₫
1.927.987 ₫ total
26 May - 27 May
includes taxes & fees
6/10 (593 reviews)
