The Best Hotels in Uptown, Collinsville - 2026 Updated Prices

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Our top choices for Uptown hotels

A spacious lobby with a high ceiling, large windows, and a variety of seating options including sofas and chairs.

1. Drury Inn & Suites St. Louis Collinsville

Eastport, 2.6 km from Uptown

Cheryl

2.926.461 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A buffet area with a wooden counter, various food items, and a coffee station.

2. Comfort Inn Collinsville near St. Louis

Eastport, 2.7 km from Uptown

Jose Rene

2.986.490 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A lobby with a central table, seating area, and a stone pillar with a mirror.

3. DoubleTree by Hilton Collinsville - St. Louis

Eastport, 2.6 km from Uptown

katie

3.648.894 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A multi-story hotel with a covered entrance, stone pillars, and a parking lot.

4. La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

Eastport, 2.9 km from Uptown

Lauren

2.716.212 ₫ total

includes taxes & fees

26 Oct - 27 Oct

A modern hotel room with a large bed, a blue chair, and a wall-mounted TV.

5. Days Inn by Wyndham Collinsville/St. Louis

Eastport, 2.7 km from Uptown

Gary

1.827.732 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with two beds, a desk, a chair, and a TV.

6. Hampton Inn Collinsville

Eastport, 2.7 km from Uptown

Ria

3.159.109 ₫ total

includes taxes & fees

13 Oct - 14 Oct

A hotel room with two beds, a desk, a chair, and a wall-mounted lamp.

7. Holiday Inn Express Troy by IHG

10 km from Uptown

Donald

3.199.680 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a bed, two bedside lamps, a cityscape painting, a wooden headboard, and a brown chair.

8. Super 8 by Wyndham Collinsville St. Louis

Eastport, 2.8 km from Uptown

Anthony

1.827.732 ₫ total

includes taxes & fees

5 Oct - 6 Oct

A lobby with checkered armchairs, a reception desk, a plant, and a tiled floor.

9. Americas Best Value Inn Collinsville St. Louis

2.3 km from Uptown

Jason

1.571.947 ₫ total

includes taxes & fees

11 Oct - 12 Oct

A modern hotel lobby with a sofa, chairs, a round table, and a decorative wall with geometric patterns.

10. Holiday Inn St. Louis Fairview Heights by IHG

7.3 km from Uptown

Melvin H

3.139.961 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A modern lounge area with a sectional sofa, ottomans, and a round table.

11. Drury Inn & Suites St. Louis Fairview Heights

7.2 km from Uptown

Sara

2.640.795 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A hotel lobby with blue seating, a flat-screen TV, and a fireplace.

12. Comfort Inn Edwardsville - St. Louis

10.9 km from Uptown

Cynthia

2.843.139 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A modern living room with a sofa, chairs, a coffee station, and a dining area.

13. Best Western St. Louis Fairview Heights

7.3 km from Uptown

LaShelle

2.344.992 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with two beds, each with a headboard, bedside tables, lamps, and a desk with a chair.

14. Econo Lodge Inn & Suites Fairview Heights - St. Louis

7.2 km from Uptown

devon

1.876.347 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A modern indoor pool area with a blue ceiling, large windows, and a pool with a metal ladder.

15. Hampton Inn O'Fallon

10.9 km from Uptown

Edmond

3.310.097 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A bar area with a wooden bar counter, multiple stools, and shelves stocked with bottles.

16. Radisson Hotel Fairview Heights - St. Louis

7 km from Uptown

Clint

2.394.293 ₫ total

includes taxes & fees

11 Oct - 12 Oct

A spacious lobby with a fireplace, a large painting, and multiple hanging light fixtures.

17. Hilton Garden Inn St. Louis Shiloh/O'Fallon IL

10.8 km from Uptown

Roxana

3.433.607 ₫ total

includes taxes & fees

11 Oct - 12 Oct

A modern lobby with patterned armchairs, a fireplace, and a large TV on the wall.

18. Holiday Inn Express & Suites Edwardsville by IHG

13.8 km from Uptown

Mary

3.553.923 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a bed, two bedside lamps, and a large framed cityscape picture on the wall.

19. Super 8 by Wyndham Fairview Heights-St. Louis

7.2 km from Uptown

Rebecca

1.795.941 ₫ total

includes taxes & fees

5 Oct - 6 Oct

A hotel room with a bed, a desk with a television, a chair, a desk lamp, and a wall-mounted rack with keys.

20. Red Roof Inn St Louis - Troy, IL

10.1 km from Uptown

Rebecca

1.867.921 ₫ total

includes taxes & fees

11 Oct - 12 Oct

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Where to stay in Uptown

Find the best Uptown areas for the activities you enjoy most.

An aerial view of a city with a prominent river, a large bridge, and surrounding buildings.

Eastport

While visiting Eastport, you might make a stop by sights like Splash City Family Waterpark and Gateway Conference Center.

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Mulberry Hills

Though Mulberry Hills may not have many top sights, you can venture to the surrounding area to see attractions like World's Largest Catsup Bottle and Kruta Bakery.

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A large, historic building with arched windows and a prominent corner entrance.

Historic Downtown Collinsville

Though Historic Downtown Collinsville may not have many top sights, you can venture to the surrounding area to see attractions like World's Largest Catsup Bottle and Kruta Bakery.

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Top Uptown Hotel Reviews

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent

"This is such a great place to stay for families. While the hotel itself is not the fanciest or best maintained, the rooms are spacious and very clean, the staff is so helpful and kind, and you can't beat the amenities!! My son and I went down to check out the signature free snack time, expecting popcorn and drinks, etc.. Turns out it was a full meal with baked potatoes, pulled pork sliders, salad, soup, nachos, etc.. It was all fresh and tasty and we did not need dinner that night. Between that and the free breakfast (also good quality) the Drury makes for great value and a lot of fun. Plus, there's a pretty decent sized pool and hot tub with a nice balcony right outside. Highly recommend!"

Home2 Suites by Hilton St. Louis Downtown

8/10 Good

"Clean rooms, friendly helpful staff, nice complimentary breakfast and nighttime security make this hotel an incredible value. The location is great too. The beds and pillows are not comfortable but they were very clean. This is not really an issue if traveling for business. I recommend this property."

Frequently asked questions

What is Uptown like?

Travellers to the Uptown neighbourhood in Collinsville will be sure to enjoy their stay. Are you looking for Uptown travel tips? Make sure that you visit Kruta Bakery and World's Largest Catsup Bottle while you're in the neighbourhood.

If I need to cancel my hotel reservation in Uptown, will I receive a refund?

Yes! Most hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Add dates, click "Search", then use the filter option "fully refundable" to get the top deals on offer in Uptown.

What is there to do in this Collinsville neighbourhood?

A few attractions you might want to check out while you're in Uptown are Kruta Bakery and World's Largest Catsup Bottle. While you're out sightseeing, Gateway Conference Center and Gateway Fun Park are a couple of additional sights to visit in Collinsville.

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Our top choices for Uptown hotels

1. Drury Inn & Suites St. Louis Collinsville

2. Comfort Inn Collinsville near St. Louis

3. DoubleTree by Hilton Collinsville - St. Louis

4. La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

5. Days Inn by Wyndham Collinsville/St. Louis

6. Hampton Inn Collinsville

7. Holiday Inn Express Troy by IHG

8. Super 8 by Wyndham Collinsville St. Louis

9. Americas Best Value Inn Collinsville St. Louis

10. Holiday Inn St. Louis Fairview Heights by IHG

11. Drury Inn & Suites St. Louis Fairview Heights

12. Comfort Inn Edwardsville - St. Louis

13. Best Western St. Louis Fairview Heights

14. Econo Lodge Inn & Suites Fairview Heights - St. Louis

15. Hampton Inn O'Fallon

16. Radisson Hotel Fairview Heights - St. Louis

17. Hilton Garden Inn St. Louis Shiloh/O'Fallon IL

18. Holiday Inn Express & Suites Edwardsville by IHG

19. Super 8 by Wyndham Fairview Heights-St. Louis

20. Red Roof Inn St Louis - Troy, IL

Where to stay in Uptown

Eastport

Mulberry Hills

Historic Downtown Collinsville

Top Uptown Hotel Reviews

Drury Plaza Hotel St. Louis at the Arch

Frequently asked questions

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