
Compare and book 2 Star hotels in O Brien, Florida
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check availability on O Brien 2 Star Hotels
Our top choices for O Brien 2-star hotels

1. Best Western Plus Lake City
Best Western Plus Lake CityLake City
9.0 out of 10, Wonderful, (1,126 reviews)
The price is 2.066.998 ₫
2.325.373 ₫ total
includes taxes & fees
1 Dec - 2 Dec

2. Comfort Suites Lake City
Comfort Suites Lake CityLake City
9.4 out of 10, Exceptional, (1,002 reviews)
The price is 2.565.751 ₫
2.886.470 ₫ total
includes taxes & fees
1 Dec - 2 Dec

3. Quality Inn Lake City
Quality Inn Lake CityLake City
8.2 out of 10, Very good, (1,005 reviews)
The price is 1.768.727 ₫
1.989.818 ₫ total
includes taxes & fees
1 Dec - 2 Dec

4. Quality Inn & Suites Live Oak I-10 Exit 283
Quality Inn & Suites Live Oak I-10 Exit 283Live Oak
7.0 out of 10, Good, (599 reviews)
The price is 2.362.173 ₫
2.598.389 ₫ total
includes taxes & fees
1 Dec - 2 Dec

5. Tru by Hilton Lake City
Tru by Hilton Lake CityLake City
9.2 out of 10, Wonderful, (1,003 reviews)
The price is 2.476.992 ₫
2.786.616 ₫ total
includes taxes & fees
1 Dec - 2 Dec

6. Hampton Inn & Suites Lake City
Hampton Inn & Suites Lake CityLake City
9.4 out of 10, Exceptional, (1,002 reviews)
The price is 2.706.114 ₫
3.044.378 ₫ total
includes taxes & fees
8 Nov - 9 Nov

7. Holiday Inn Express & Suites Live Oak by IHG
Holiday Inn Express & Suites Live Oak by IHGLive Oak
8.4 out of 10, Very good, (897 reviews)
The price is 2.838.220 ₫
3.122.042 ₫ total
includes taxes & fees
8 Nov - 9 Nov

8. Days Inn by Wyndham Lake City I-10
Days Inn by Wyndham Lake City I-10Lake City
7.2 out of 10, Good, (1,002 reviews)
The price is 1.568.762 ₫
1.764.857 ₫ total
includes taxes & fees
3 Nov - 4 Nov

9. Americas Best Value Inn Lake City
Americas Best Value Inn Lake CityLake City
8.6 out of 10, Excellent, (1,003 reviews)
The price is 1.834.522 ₫
2.064.160 ₫ total
includes taxes & fees
3 Nov - 4 Nov

10. Baymont by Wyndham Lake City I-75
Baymont by Wyndham Lake City I-75Lake City
5.0 out of 10, (1,006 reviews)
The price is 1.491.356 ₫
1.677.904 ₫ total
includes taxes & fees
3 Nov - 4 Nov

11. Motel 6 – Lake City, Fl – Medical Center
Motel 6 – Lake City, Fl – Medical CenterLake City
7.4 out of 10, Good, (250 reviews)
The price is 1.883.288 ₫
2.118.699 ₫ total
includes taxes & fees
1 Dec - 2 Dec

12. Hampton Inn & Suites Alachua I-75
Hampton Inn & Suites Alachua I-75Alachua
9.4 out of 10, Exceptional, (570 reviews)
The price is 2.916.916 ₫
3.281.531 ₫ total
includes taxes & fees
15 Nov - 16 Nov

13. Days Inn by Wyndham Lake City I-75
Days Inn by Wyndham Lake City I-75Lake City
7.6 out of 10, Good, (1,001 reviews)
The price is 1.732.604 ₫
1.949.179 ₫ total
includes taxes & fees
1 Dec - 2 Dec

14. Quality Inn White Springs Suwanee
Quality Inn White Springs SuwaneeWhite Springs
7.2 out of 10, Good, (707 reviews)
The price is 1.568.504 ₫
1.725.354 ₫ total
includes taxes & fees
1 Dec - 2 Dec

15. Gateway Inn
Gateway InnLake City
7.8 out of 10, Good, (211 reviews)
The price is 1.250.616 ₫
1.406.943 ₫ total
includes taxes & fees
3 Nov - 4 Nov

16. Palms Garden Inn
Palms Garden InnLake City
7.6 out of 10, Good, (659 reviews)
The price is 1.779.048 ₫
2.001.429 ₫ total
includes taxes & fees
3 Nov - 4 Nov

17. BlueGem Motel
BlueGem MotelHigh Springs
9.2 out of 10, Wonderful, (485 reviews)
The price is 2.405.261 ₫
2.705.919 ₫ total
includes taxes & fees
4 Nov - 5 Nov

18. Econo Lodge Live Oak
Econo Lodge Live OakLive Oak
7.0 out of 10, Good, (325 reviews)
The price is 1.887.416 ₫
2.076.158 ₫ total
includes taxes & fees
4 Nov - 5 Nov

20. Super 8 by Wyndham Lake City
Super 8 by Wyndham Lake CityLake City
7.4 out of 10, Good, (765 reviews)
The price is 1.579.082 ₫
1.776.467 ₫ total
includes taxes & fees
1 Dec - 2 Dec
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 3-star hotels
Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in O Brien.

La Quinta Inn & Suite by Wyndham Lake City
165NW CALI DRIVE Lake City FL
The price is 2.415.067 ₫ per night from 1 Dec to 2 Dec
2.415.067 ₫
2.716.950 ₫ total
1 Dec - 2 Dec
includes taxes & fees
8.8/10 Excellent! (1,200 reviews)
Still don't see what you're looking for?
See all properties in O Brien.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about O Brien
Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

Top O Brien Hotel Reviews

Days Inn by Wyndham Lake City I-10
10/10 Excellent

Americas Best Value Inn Lake City
10/10 Excellent






























































