A calm river with clear water, surrounded by dense trees and rocky banks.

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Our top choices for O Brien 2-star hotels

1. Best Western Plus Lake City

Best Western Plus Lake City
2.5 star property
Lake City
9.0 out of 10, Wonderful, (1,126 reviews)
"Staff was helpful, room was clean and the breakfast was amazing."
United States
Melissa
The price is 2.066.998 ₫
2.325.373 ₫ total
includes taxes & fees
1 Dec - 2 Dec
Best Western Plus Lake City

2. Comfort Suites Lake City

Comfort Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,002 reviews)
"Clean, good breakfast, family friendly."
United States
Brooke
The price is 2.565.751 ₫
2.886.470 ₫ total
includes taxes & fees
1 Dec - 2 Dec
Comfort Suites Lake City

3. Quality Inn Lake City

Quality Inn Lake City
2.5 star property
Lake City
8.2 out of 10, Very good, (1,005 reviews)
"Very nice hotel!"
United States
Mary
The price is 1.768.727 ₫
1.989.818 ₫ total
includes taxes & fees
1 Dec - 2 Dec
Quality Inn Lake City

4. Quality Inn & Suites Live Oak I-10 Exit 283

Quality Inn & Suites Live Oak I-10 Exit 283
2.5 star property
Live Oak
7.0 out of 10, Good, (599 reviews)
"Smooth check in good breakfast met all of our needs"
United States
Kayla
The price is 2.362.173 ₫
2.598.389 ₫ total
includes taxes & fees
1 Dec - 2 Dec
Quality Inn & Suites Live Oak I-10 Exit 283

5. Tru by Hilton Lake City

Tru by Hilton Lake City
2.5 star property
Lake City
9.2 out of 10, Wonderful, (1,003 reviews)
"Clean and well maintained hotel"
United States
Carlos
The price is 2.476.992 ₫
2.786.616 ₫ total
includes taxes & fees
1 Dec - 2 Dec
Tru by Hilton Lake City

6. Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,002 reviews)
"I have stayed here several times. Staff is at least very friendly and accommodating properties very clean. We enjoyed our stay."
United States
Eileen
The price is 2.706.114 ₫
3.044.378 ₫ total
includes taxes & fees
8 Nov - 9 Nov
Hampton Inn & Suites Lake City

7. Holiday Inn Express & Suites Live Oak by IHG

Holiday Inn Express & Suites Live Oak by IHG
2.5 star property
Live Oak
8.4 out of 10, Very good, (897 reviews)
"Lee and all staff were so wonderful. Rooms clean-great stay"
United States
KRISTEN
The price is 2.838.220 ₫
3.122.042 ₫ total
includes taxes & fees
8 Nov - 9 Nov
Holiday Inn Express & Suites Live Oak by IHG

8. Days Inn by Wyndham Lake City I-10

Days Inn by Wyndham Lake City I-10
2.0 star property
Lake City
7.2 out of 10, Good, (1,002 reviews)
"The staff was very friendly checking in and checking out. The room was cleaned and well maintained."
United States
William
The price is 1.568.762 ₫
1.764.857 ₫ total
includes taxes & fees
3 Nov - 4 Nov
Days Inn by Wyndham Lake City I-10

9. Americas Best Value Inn Lake City

Americas Best Value Inn Lake City
2.0 star property
Lake City
8.6 out of 10, Excellent, (1,003 reviews)
"The room was clean and the A/C was nice and cold. The staff was very courteous and helpful."
United States
Hazel
The price is 1.834.522 ₫
2.064.160 ₫ total
includes taxes & fees
3 Nov - 4 Nov
Americas Best Value Inn Lake City

10. Baymont by Wyndham Lake City I-75

Baymont by Wyndham Lake City I-75
2.5 star property
Lake City
5.0 out of 10, (1,006 reviews)
"Easy parking room clean"
United States
Pennee
The price is 1.491.356 ₫
1.677.904 ₫ total
includes taxes & fees
3 Nov - 4 Nov
Baymont by Wyndham Lake City I-75

11. Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center
2.0 star property
Lake City
7.4 out of 10, Good, (250 reviews)
"Amazing stay"
United States
Pennee
The price is 1.883.288 ₫
2.118.699 ₫ total
includes taxes & fees
1 Dec - 2 Dec
Motel 6 – Lake City, Fl – Medical Center

12. Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
2.5 star property
Alachua
9.4 out of 10, Exceptional, (570 reviews)
"Great breakfast!"
United States
Pamela
The price is 2.916.916 ₫
3.281.531 ₫ total
includes taxes & fees
15 Nov - 16 Nov
Hampton Inn & Suites Alachua I-75

13. Days Inn by Wyndham Lake City I-75

Days Inn by Wyndham Lake City I-75
2.0 star property
Lake City
7.6 out of 10, Good, (1,001 reviews)
"Nice breakfast."
United States
Nathan
The price is 1.732.604 ₫
1.949.179 ₫ total
includes taxes & fees
1 Dec - 2 Dec
Days Inn by Wyndham Lake City I-75

14. Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee
2.5 star property
White Springs
7.2 out of 10, Good, (707 reviews)
"Great breakfast options quiet clean place to stay"
United States
Pennee
The price is 1.568.504 ₫
1.725.354 ₫ total
includes taxes & fees
1 Dec - 2 Dec
Quality Inn White Springs Suwanee

15. Gateway Inn

Gateway Inn
2.5 star property
Lake City
7.8 out of 10, Good, (211 reviews)
"Nice modern, clean hotel room"
United States
Karen
The price is 1.250.616 ₫
1.406.943 ₫ total
includes taxes & fees
3 Nov - 4 Nov
Gateway Inn

16. Palms Garden Inn

Palms Garden Inn
2.0 star property
Lake City
7.6 out of 10, Good, (659 reviews)
"Very good place nice and quiet and clean"
United States
Igor
The price is 1.779.048 ₫
2.001.429 ₫ total
includes taxes & fees
3 Nov - 4 Nov
Palms Garden Inn

17. BlueGem Motel

BlueGem Motel
2.0 star property
High Springs
9.2 out of 10, Wonderful, (485 reviews)
"Very clean rooms and homey atmosphere!"
United States
Myra
The price is 2.405.261 ₫
2.705.919 ₫ total
includes taxes & fees
4 Nov - 5 Nov
BlueGem Motel

18. Econo Lodge Live Oak

Econo Lodge Live Oak
2.0 star property
Live Oak
7.0 out of 10, Good, (325 reviews)
"I definitely will not recommend anyone to book a room there. The rooms are in bad sharp. The whole hotel need remodel."
United States
Alexia
The price is 1.887.416 ₫
2.076.158 ₫ total
includes taxes & fees
4 Nov - 5 Nov
Econo Lodge Live Oak

19. Royal Inn

Royal Inn
2.0 star property
Alachua
7.2 out of 10, Good, (208 reviews)
"Bugs in room"
United States
James
The price is 1.857.744 ₫
2.089.962 ₫ total
includes taxes & fees
3 Nov - 4 Nov
Royal Inn

20. Super 8 by Wyndham Lake City

Super 8 by Wyndham Lake City
2.0 star property
Lake City
7.4 out of 10, Good, (765 reviews)
"Rooms where very clean and staff was so helpful and nice."
United States
Scott
The price is 1.579.082 ₫
1.776.467 ₫ total
includes taxes & fees
1 Dec - 2 Dec
Super 8 by Wyndham Lake City
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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

A calm river surrounded by trees reflecting in the water.

Top O Brien Hotel Reviews