A calm river with clear water, surrounded by dense trees and rocky banks.

Find hotels in O Brien, FL from 1.725.354 ₫

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Check prices for these dates

This weekend
6 Nov - 8 Nov
Next weekend
13 Nov - 15 Nov

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Our top choices for O Brien hotels

A La Quinta hotel with a modern facade, multiple windows, and a well-lit entrance.

1. La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City
3.0 star property
Lake City
8.8 out of 10, Excellent, (1,200 reviews)
"Very nice visit, very clean room, excellent staff, great breakfast, easy parking"
United States
Emory
The price is 2.415.067 ₫
2.716.950 ₫ total
includes taxes & fees
1 Dec - 2 Dec
La Quinta Inn & Suite by Wyndham Lake City
A spacious living area with a grey sofa, a coffee table, and a TV stand.

2. Best Western Plus Lake City

Best Western Plus Lake City
2.5 star property
Lake City
9.0 out of 10, Wonderful, (1,126 reviews)
"Staff was helpful, room was clean and the breakfast was amazing."
United States
Melissa
The price is 2.066.998 ₫
2.325.373 ₫ total
includes taxes & fees
1 Dec - 2 Dec
Best Western Plus Lake City
A hotel room with a gray sofa, a bed with white linens, a desk with a chair, and a window with blinds.

3. Comfort Suites Lake City

Comfort Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,002 reviews)
"Clean, good breakfast, family friendly."
United States
Brooke
The price is 2.565.751 ₫
2.886.470 ₫ total
includes taxes & fees
1 Dec - 2 Dec
Comfort Suites Lake City
A self-service beverage station with a variety of drinks, snacks, and a refrigerated section.

4. Tru by Hilton Lake City

Tru by Hilton Lake City
2.5 star property
Lake City
9.2 out of 10, Wonderful, (1,002 reviews)
"Clean and well maintained hotel"
United States
Carlos
The price is 2.476.992 ₫
2.786.616 ₫ total
includes taxes & fees
1 Dec - 2 Dec
Tru by Hilton Lake City
A picnic table with a potted plant, located in a grassy area with a tree and a road in the background.

5. Americas Best Value Inn Lake City

Americas Best Value Inn Lake City
2.0 star property
Lake City
8.6 out of 10, Excellent, (1,003 reviews)
"The room was clean and the A/C was nice and cold. The staff was very courteous and helpful."
United States
Hazel
The price is 1.834.522 ₫
2.064.160 ₫ total
includes taxes & fees
3 Nov - 4 Nov
Americas Best Value Inn Lake City
Lobby

6. Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,002 reviews)
"I have stayed here several times. Staff is at least very friendly and accommodating properties very clean. We enjoyed our stay."
United States
Eileen
The price is 2.706.114 ₫
3.044.378 ₫ total
includes taxes & fees
8 Nov - 9 Nov
Hampton Inn & Suites Lake City
A buffet with various food items, including omelets and baked goods, served in metal containers.

7. Holiday Inn Express & Suites Live Oak by IHG

Holiday Inn Express & Suites Live Oak by IHG
2.5 star property
Live Oak
8.4 out of 10, Very good, (897 reviews)
"Lee and all staff were so wonderful. Rooms clean-great stay"
United States
KRISTEN
The price is 2.838.220 ₫
3.122.042 ₫ total
includes taxes & fees
8 Nov - 9 Nov
Holiday Inn Express & Suites Live Oak by IHG
An indoor swimming pool with clear water, surrounded by glass doors and windows, and a wooden deck area.

8. Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City
3.0 star property
Lake City
9.0 out of 10, Wonderful, (298 reviews)
"Stayed here on the way to Disney so wouldn't have to drive so far one way for the family. It was a nice place to stay."
United States
Anthony
The price is 2.671.797 ₫
3.005.772 ₫ total
includes taxes & fees
8 Nov - 9 Nov
Fairfield Inn & Suites Lake City
A multi-story hotel with a modern design, featuring a prominent entrance and a parking area.

9. Courtyard By Marriott Lake City

Courtyard By Marriott Lake City
3.0 star property
Lake City
9.6 out of 10, Exceptional, (311 reviews)
"So nice and clean and quiet!"
United States
sheryl
The price is 2.995.612 ₫
3.370.064 ₫ total
includes taxes & fees
8 Nov - 9 Nov
Courtyard By Marriott Lake City
An outdoor patio area with wicker chairs, a round table, and a fire pit.

10. TownePlace Suites by Marriott Lake City

TownePlace Suites by Marriott Lake City
3.0 star property
Lake City
9.6 out of 10, Exceptional, (151 reviews)
"Very clean! Comfy beds!"
United States
John
The price is 3.328.458 ₫
3.744.516 ₫ total
includes taxes & fees
15 Nov - 16 Nov
TownePlace Suites by Marriott Lake City
A hotel room with two beds, a TV, a desk with a lamp, and a window with blinds.

11. Holiday Inn & Suites Lake City by IHG

Holiday Inn & Suites Lake City by IHG
3.0 star property
Lake City
8.6 out of 10, Excellent, (1,003 reviews)
"Next time I am needing motel in Lake City, will plan to stay at this location."
United States
William
The price is 2.606.002 ₫
2.931.753 ₫ total
includes taxes & fees
8 Nov - 9 Nov
Holiday Inn & Suites Lake City by IHG
An outdoor patio with a stone fire pit, grey cushioned seating, and wicker ottomans.

12. Home2 Suites by Hilton Lake City

Home2 Suites by Hilton Lake City
3.0 star property
Lake City
9.4 out of 10, Exceptional, (831 reviews)
"Big, clean room and the staff was very friendly"
United States
Laurie
The price is 3.062.181 ₫
3.444.825 ₫ total
includes taxes & fees
8 Nov - 9 Nov
Home2 Suites by Hilton Lake City
A hotel room with two beds, a desk, a chair, a lamp, and a view of the outdoors.

13. Quality Inn & Suites Live Oak I-10 Exit 283

Quality Inn & Suites Live Oak I-10 Exit 283
2.5 star property
Live Oak
7.0 out of 10, Good, (599 reviews)
"Smooth check in good breakfast met all of our needs"
United States
Kayla
The price is 2.362.173 ₫
2.598.389 ₫ total
includes taxes & fees
1 Dec - 2 Dec
Quality Inn & Suites Live Oak I-10 Exit 283
A hotel room with a large bed, a desk with a computer, a television, and a window with curtains.

14. Super 8 by Wyndham Lake City

Super 8 by Wyndham Lake City
2.0 star property
Lake City
7.4 out of 10, Good, (765 reviews)
"Rooms where very clean and staff was so helpful and nice."
United States
Scott
The price is 1.579.082 ₫
1.776.467 ₫ total
includes taxes & fees
1 Dec - 2 Dec
Super 8 by Wyndham Lake City
A modern kitchen with a large window, a flat-screen TV, and a coffee machine.

15. Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee
2.5 star property
White Springs
7.2 out of 10, Good, (707 reviews)
"Great breakfast options quiet clean place to stay"
United States
Pennee
The price is 1.568.504 ₫
1.725.354 ₫ total
includes taxes & fees
1 Dec - 2 Dec
Quality Inn White Springs Suwanee
A hotel room with two beds, a desk, a chair, a sink, and a painting of a pier and sunset.

16. Days Inn by Wyndham Lake City I-10

Days Inn by Wyndham Lake City I-10
2.0 star property
Lake City
7.2 out of 10, Good, (1,002 reviews)
"The staff was very friendly checking in and checking out. The room was cleaned and well maintained."
United States
William
The price is 1.568.762 ₫
1.764.857 ₫ total
includes taxes & fees
3 Nov - 4 Nov
Days Inn by Wyndham Lake City I-10
A covered outdoor area with a paved walkway, benches, and potted plants.

17. Cindys Motel

Cindys Motel
2.5 star property
Mayo
8.8 out of 10, Excellent, (140 reviews)
"wonderful, quiet, a hide a way for a fun stay"
United States
Diane
The price is 2.264.125 ₫
2.446.868 ₫ total
includes taxes & fees
3 Nov - 4 Nov
Cindys Motel
A reception area with a stone wall, a blue accent wall, a clock, and a window with a view of the parking lot.

18. Regal Inn

Regal Inn
2.5 star property
Lake City
8.6 out of 10, Excellent, (620 reviews)
"This is the second time I’ve stayed at this hotel. Convenient to restaurants and gas stations. Look forward to staying again."
United States
Gerardo
The price is 1.600.756 ₫
1.800.722 ₫ total
includes taxes & fees
4 Nov - 5 Nov
Regal Inn
A hotel reception area with a reception desk, seating area, and a view of the parking lot.

19. Econo Lodge Live Oak

Econo Lodge Live Oak
2.0 star property
Live Oak
7.0 out of 10, Good, (325 reviews)
"I definitely will not recommend anyone to book a room there. The rooms are in bad sharp. The whole hotel need remodel."
United States
Alexia
The price is 1.887.416 ₫
2.076.158 ₫ total
includes taxes & fees
4 Nov - 5 Nov
Econo Lodge Live Oak
A kitchen counter with a coffee maker, a 'Welcome' sign, and a vase of flowers.

20. Driftwood Inn

Driftwood Inn
2.0 star property
Lake City
7.8 out of 10, Good, (809 reviews)
"Clean room, polite helpful staff, ac cool, convent to shops."
United States
Frank
The price is 1.351.212 ₫
1.520.114 ₫ total
includes taxes & fees
5 Nov - 6 Nov
Driftwood Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare top hotels in O Brien

A La Quinta hotel with a modern facade, multiple windows, and a well-lit entrance.

La Quinta Inn & Suite by Wyndham Lake City

3.0 star property
Lake City
View
A spacious living area with a grey sofa, a coffee table, and a TV stand.

Best Western Plus Lake City

2.5 star property
Lake City
View
A hotel room with a gray sofa, a bed with white linens, a desk with a chair, and a window with blinds.

Comfort Suites Lake City

2.5 star property
Lake City
View
A self-service beverage station with a variety of drinks, snacks, and a refrigerated section.

Tru by Hilton Lake City

2.5 star property
Lake City
View
A picnic table with a potted plant, located in a grassy area with a tree and a road in the background.

Americas Best Value Inn Lake City

2.0 star property
Lake City
View
8.8
Excellent
1,200 reviews
9.0
Wonderful
1,126 reviews
9.4
Exceptional
1,002 reviews
9.2
Wonderful
1,002 reviews
8.6
Excellent
1,003 reviews
The price is 2.415.067 ₫
2.716.950 ₫ total
includes taxes & fees
1 Dec - 2 Dec
The price is 2.066.998 ₫
2.325.373 ₫ total
includes taxes & fees
1 Dec - 2 Dec
The price is 2.565.751 ₫
2.886.470 ₫ total
includes taxes & fees
1 Dec - 2 Dec
The price is 2.476.992 ₫
2.786.616 ₫ total
includes taxes & fees
1 Dec - 2 Dec
The price is 1.834.522 ₫
2.064.160 ₫ total
includes taxes & fees
3 Nov - 4 Nov
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

See all hotels in O Brien
A calm river surrounded by trees reflecting in the water.

Top O Brien Hotel Reviews

La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City

10/10 Excellent
"Nice newer looking property would stay again. Overall a 5 star"
Michael 1-night trip
Posted 19 hours ago
La Quinta Inn & Suite by Wyndham Lake City

More cheap stays in O Brien

Quality Inn Lake City

Quality Inn Lake City

285 Sw Commerce Dr Lake City FL
The price is 1.768.727 ₫ per night from 1 Dec to 2 Dec
1.768.727 ₫
1.989.818 ₫ total
1 Dec - 2 Dec
includes taxes & fees

Hotels in O Brien with star rating

Frequently asked questions

What's the seasonal weather in O Brien?
The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 14°C. Average annual precipitation for O Brien is 1278 mm.