Compare and book 4 Star hotels in Eastern Panama, Panama

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Check availability on Eastern Panama 4 Star Hotels

Tonight
4 Jul - 5 Jul
Tomorrow
5 Jul - 6 Jul
This weekend
4 Jul - 6 Jul
Next weekend
11 Jul - 13 Jul

Top Eastern Panama 4 Star Hotels

Mandalas Ecolodge
Exterior

Mandalas Ecolodge

4.0 star property
Mandalas Ecolodge
Ordovician Beach Resort
Luxury Suite | 1 bedroom, Egyptian cotton sheets, premium bedding, pillow-top beds

Ordovician Beach Resort

4.5 star property
10.0 out of 10, Exceptional, (1)
"Excelente para casais "
Ordovician Beach Resort
El Otro Lado
Outdoor pool

El Otro Lado

4.0 star property
9.8 out of 10, Exceptional, (8)
"Amazing"
El Otro Lado
Portobello Historico
Premium bedding, down duvets, individually decorated

Portobello Historico

4.0 star property
Portobello Historico
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Learn more about Eastern Panama

Head to sights like Cayos Holandeses and Chagres National Park as you discover Eastern Panama.

See all hotels in Eastern Panama

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Eastern Panama?
With Expedia's handy filter tool, scoring an awesome deal on a 4-star hotel in Eastern Panama just got simpler. Start by keying in your chosen arrival date and length of your holiday. Then sort the results by price and pick the option that best matches your budget and style.

  • Search for the lowest price

What's the difference between 5-star and 4-star hotels in Eastern Panama?
If you decide to book a stay at a 4-star hotel in Eastern Panama, you'll usually find lots of conveniences to keep you comfortable, such as a pool, restaurant and gym. You can experience top-quality service and upscale accommodation. Go for a 5-star hotel and you'll have access to a few more bells and whistles --- think on-site spas, concierge assistance and nightly turndown services. You'll most likely get extra amenities and premium services at a 5-star retreat, but both are terrific options for luxury guests.
Does Eastern Panama have any 4-star all-inclusive resorts?
Use our "All inclusive" filter to find your next getaway in Eastern Panama where just about everything is taken care of, from your meals to your accommodation, activities and entertainment. We can also help you find standard 4-star stays in and around this leading destination.