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Our top choices for La Mesa 4-star hotels

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (3,367 reviews)
"Great place to stay!"
United States
CINDY
The price is 6.100.460 ₫
8.333.631 ₫ total
includes taxes & fees
11 Mar - 12 Mar
Hard Rock Hotel San Diego

Paradise Point Resort & Spa

Paradise Point Resort & Spa
4.0 star property
Mission Bay
8.8 out of 10, Excellent, (2,438 reviews)
"Clean Rooms, staff very friendly, very relaxing place "
United States
AlmaDelia
The price is 5.345.427 ₫
7.529.397 ₫ total
includes taxes & fees
25 Mar - 26 Mar
Paradise Point Resort & Spa

Embassy Suites by Hilton San Diego Bay Downtown

Embassy Suites by Hilton San Diego Bay Downtown
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1,660 reviews)
"Very easy vacation, convenient breakfast as well as location."
United States
Kathy
The price is 5.320.522 ₫
7.114.263 ₫ total
includes taxes & fees
3 Apr - 4 Apr
Embassy Suites by Hilton San Diego Bay Downtown

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay
8.4 out of 10, Very good, (1,351 reviews)
"Great place for our family getaway! Loved the S’mores on the beach! "
United States
Dani
The price is 5.967.282 ₫
8.237.194 ₫ total
includes taxes & fees
8 Mar - 9 Mar
San Diego Mission Bay Resort

San Diego Marriott La Jolla

San Diego Marriott La Jolla
4.0 star property
University City
8.6 out of 10, Excellent, (2,275 reviews)
"Great stay"
United States
Braulio
The price is 4.254.096 ₫
4.894.661 ₫ total
includes taxes & fees
7 Mar - 8 Mar
San Diego Marriott La Jolla

Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina
4.0 star property
Mission Bay
8.4 out of 10, Very good, (1,604 reviews)
"Balcony view is awesome, clean room, staff at counter and restaurant service was stunning."
United States
francisco
The price is 4.422.899 ₫
6.468.686 ₫ total
includes taxes & fees
11 Mar - 12 Mar
Hyatt Regency Mission Bay Spa and Marina

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
Downtown San Diego
8.4 out of 10, Very good, (6,066 reviews)
"Great place to stay"
United States
David
The price is 3.964.725 ₫
5.503.717 ₫ total
includes taxes & fees
29 Mar - 30 Mar
Wyndham San Diego Bayside

San Diego Marriott Gaslamp Quarter

San Diego Marriott Gaslamp Quarter
4.0 star property
Downtown San Diego
8.8 out of 10, Excellent, (1,666 reviews)
"Lovely hotel and perfect location near many amenities. "
United States
Johan
The price is 4.204.371 ₫
4.874.759 ₫ total
includes taxes & fees
2 Apr - 3 Apr
San Diego Marriott Gaslamp Quarter

Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
University Heights
9.2 out of 10, Wonderful, (1,501 reviews)
"Stunning hotel, I could have stayed there all day looking at every little design detail. "
United States
Holly
The price is 5.967.282 ₫
6.847.455 ₫ total
includes taxes & fees
4 Mar - 5 Mar
Lafayette Hotel & Club

DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar
4.0 star property
Carmel Valley
8.4 out of 10, Very good, (2,124 reviews)
"The room was great, the restaurant/bar was so good, and the front desk was nice! We had the best time during our stay! "
United States
Courtney
The price is 3.553.008 ₫
4.048.475 ₫ total
includes taxes & fees
2 Apr - 3 Apr
DoubleTree by Hilton San Diego - Del Mar

Hotel Indigo San Diego-Gaslamp Quarter by IHG

Hotel Indigo San Diego-Gaslamp Quarter by IHG
4.0 star property
Downtown San Diego
8.8 out of 10, Excellent, (1,010 reviews)
"Friendly staff "
United States
Luis
The price is 4.299.570 ₫
6.012.604 ₫ total
includes taxes & fees
3 Apr - 4 Apr
Hotel Indigo San Diego-Gaslamp Quarter by IHG

Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark
4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (2,066 reviews)
"Great location, clean and comfortable rooms, friendly staff."
United States
Maya
The price is 5.072.412 ₫
7.059.551 ₫ total
includes taxes & fees
3 Apr - 4 Apr
Omni San Diego Hotel at the Ballpark

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
Harbor Island
8.4 out of 10, Very good, (3,357 reviews)
"Love this hotel will always stay here when I come to San Diego "
United States
Darlene
The price is 3.257.250 ₫
4.890.597 ₫ total
includes taxes & fees
1 Apr - 2 Apr
Sheraton San Diego Resort

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (2,021 reviews)
"Outstanding hotel! Friendly courteous staff and amazing room with breathtaking view. "
United States
Jonny
The price is 5.208.029 ₫
7.412.740 ₫ total
includes taxes & fees
2 Apr - 3 Apr
Marriott Marquis San Diego Marina

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (2,915 reviews)
"Perfect place to stay. Staff was super helpful and resouceful. Lots of little extras to satisfy the guests. Will definitely stay here again. "
United States
Gloria
The price is 5.706.702 ₫
8.036.547 ₫ total
includes taxes & fees
13 Mar - 14 Mar
Manchester Grand Hyatt San Diego

The Westin San Diego Bayview

The Westin San Diego Bayview
4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1,152 reviews)
"Super clean room, great staff, great hotel amenities, perfect location, and the best bed & shower ever."
United States
Alexis
The price is 4.186.218 ₫
5.609.131 ₫ total
includes taxes & fees
3 Apr - 4 Apr
The Westin San Diego Bayview

Margaritaville Hotel San Diego Gaslamp Quarter

Margaritaville Hotel San Diego Gaslamp Quarter
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1,250 reviews)
"Perfect location in the Gaslamp District. Rooms were large & clean with friendly staff. "
United States
Ginger
The price is 4.922.765 ₫
6.921.512 ₫ total
includes taxes & fees
8 Mar - 9 Mar
Margaritaville Hotel San Diego Gaslamp Quarter

Westgate Hotel

Westgate Hotel
4.5 star property
Downtown San Diego
9.2 out of 10, Wonderful, (1,007 reviews)
"Great stay"
United States
ESMERALDA
Westgate Hotel

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (2,944 reviews)
"Excellent facilities and location "
United States
Felix
Legacy Resort Hotel & Spa

Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla
4.0 star property
University City
8.8 out of 10, Excellent, (1,873 reviews)
"Great included breakfast!"
United States
Gina
The price is 4.322.664 ₫
5.714.299 ₫ total
includes taxes & fees
7 Mar - 8 Mar
Embassy Suites by Hilton San Diego La Jolla
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in La Mesa.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about La Mesa

Nestled between rolling hills, this charming suburb offers hiking trails through Mission Trails Park and Lake Murray's scenic waterfront paths. Visit the vibrant farmers market on Fridays, then explore the antique shops and local breweries along La Mesa Boulevard's historic district.

View from Mount Helix, in La Mesa, near San Diego, California

Top La Mesa Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in La Mesa?
San Diego Marriott Mission Valley is a 4-star hotel in La Mesa that's popular among Expedia guests. A swimming pool and concierge services are some of its many amenities. Travellers also recommend Sheraton Mission Valley San Diego Hotel. From concierge services to a spa tub, it comes with conveniences that cater to every aspect of your relaxation and enjoyment.
How much does it cost to stay in a 4-star hotel in La Mesa?
With Expedia's search and sort filters, landing a great deal on a 4-star hotel in La Mesa just got simpler. Start by keying in your chosen arrival date and length of your break. Then list the results by price and choose a hotel that best fits your style and budget.

  • Search for the lowest price from 10.282.690 ₫

What's the difference between 5-star and 4-star hotels in La Mesa?
Treat yourself to luxury living during your La Mesa holiday by choosing a 4-star hotel. As well as featuring upmarket surroundings, these properties are usually packed with amenities, including complimentary bathrobes, large beds and more. A 5-star hotel will go the extra mile to make your stay an even more lavish and special one. 24-hour concierge assistance, elegant décor and world-class dining are only the start of the superior services and conveniences you'll likely be able to enjoy.