A cityscape with historic buildings, a prominent church with a dome, and mountains in the background.

Compare and book 4 Star hotels in Palermo, Sicily

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Palermo 4 Star Hotels

Tonight
6 Oct - 7 Oct
Tomorrow
7 Oct - 8 Oct
This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Our top choices for Palermo 4-star hotels

A multi-story hotel with a prominent entrance labeled "ASTORIA PALACE."
A hotel room with a dining table set with a variety of desserts, two glasses of champagne, and a vase of flowers.
An outdoor dining area with tables and chairs, a covered seating area, and a view of a cityscape with buildings and a crane in the background.
A buffet with various food items covered in glass domes, including meats, cheeses, and breads.

1. Astoria Palace Hotel

Astoria Palace Hotel
Monte Pellegrino
Australia
Blagoy
1.900.787 ₫
2.353.373 ₫ total
includes taxes & fees
25 Oct - 26 Oct
Astoria Palace Hotel
A spacious courtyard with a central fountain, surrounded by white wicker furniture and columns.
A historic building with a central entrance, multiple windows, and a flag.
A spacious corridor with high ceilings and classical architecture, featuring columns and arches.
A spacious indoor area with a high ceiling, a chandelier, and a seating arrangement including tables and chairs.

2. Grand Hotel Piazza Borsa

Grand Hotel Piazza Borsa
Palermo Historical Center
United Kingdom
Julie Margaret Owen
4.454.660 ₫
5.162.633 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Grand Hotel Piazza Borsa
A terrace with wicker furniture, a potted plant, and a view of the cityscape.
A hotel room with a bed, a desk, a chair, a bathroom with a sink, mirror, and towel rack.
A modern hotel lobby with a reception desk, seating area, and large windows.
A modern room with a bench, a round table, and two large abstract paintings on the wall.

3. Hotel Politeama

Hotel Politeama
Politeama
Japan
Noriko
2.778.860 ₫
3.319.252 ₫ total
includes taxes & fees
3 Nov - 4 Nov
Hotel Politeama
A man dining at a table with a view of a cruise ship and a building labeled "USCITA ELN" in the background.
A modern bar area with a curved counter, white chairs, and a glass partition.
A modern hotel room with a large bed, a small kitchenette, and a bathroom visible through an open door.
A modern hotel lobby with a red reception desk, a staircase, and potted plants.

4. President Hotel Palermo

President Hotel Palermo
Politeama
United States
Jeffrey
2.534.383 ₫
3.050.328 ₫ total
includes taxes & fees
1 Nov - 2 Nov
President Hotel Palermo
A grand dining hall with ornate ceiling artwork, chandeliers, and multiple dining tables.
A grand staircase with marble columns and a statue at the top.
A grand lobby with a large arched doorway, a tufted sofa, and two ornate chairs.
A room with a large ornate table, two chairs, and a chandelier.

5. Eurostars Centrale Palace

Eurostars Centrale Palace
Palermo Historical Center
United States
Shaz
3.185.082 ₫
3.766.097 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Eurostars Centrale Palace
A modern bedroom with a large bed, a bedside table, a mirror, and a wall-mounted artwork.
A courtyard with a stone floor, yellow chairs, potted plants, and a building entrance.
A view through a window of a building with a large dome and a window with a blue frame.
A spa area with a pool, lounge chairs, and candles.

6. Quintocanto Hotel and Spa

Quintocanto Hotel and Spa
Palermo Historical Center
United States
molly
3.221.673 ₫
3.806.348 ₫ total
includes taxes & fees
5 Nov - 6 Nov
Quintocanto Hotel and Spa
A table with pastries, a teapot, and a cup, with a scenic view through large windows.
A clear blue pool with white lounge chairs and a railing.
A spacious lobby with a chandelier, white sofas, and a reception desk.
A hotel with a large sign reading "SAN PAOLO PALACE" and a well-lit entrance area with potted plants.

7. San Paolo Palace Hotel

San Paolo Palace Hotel
Settecannoli
United States
CORINA
2.169.499 ₫
2.648.956 ₫ total
includes taxes & fees
1 Nov - 2 Nov
San Paolo Palace Hotel
Terrace/patio
Room
Front of property
A spacious lobby with a modern design, featuring a large potted plant, seating area, and a view of the cityscape through the glass wall.

8. Cristal Hotel Palermo

Cristal Hotel Palermo
Politeama
Canada
Catherine
2.343.662 ₫
2.840.535 ₫ total
includes taxes & fees
4 Nov - 5 Nov
Cristal Hotel Palermo
A hotel with a swimming pool, lounge chairs, and a palm tree.
A hotel room with a large bed, a nightstand, a wall-mounted lamp, and a view of the sea through a large window.
A room with a sofa, a small table, and a view of palm trees and a beach.
A bar area with a marble countertop, patterned wall, and bar stools.

9. NH Palermo

NH Palermo
Palermo Historical Center
United Kingdom
Mia Susan
3.712.216 ₫
4.345.944 ₫ total
includes taxes & fees
3 Nov - 4 Nov
NH Palermo
A historic building with classical architecture, a fountain, and a street with cars and pedestrians.
A modern interior with a glass table, a bowl of fruit, and a wine glass.
Exterior
A modern lobby with a flat-screen TV mounted on a brick wall, a reception desk, and a seating area with colorful chairs.

10. Mercure Hotel Palermo Centro

Mercure Hotel Palermo Centro
Politeama
United States
Van
2.094.751 ₫
2.566.733 ₫ total
includes taxes & fees
2 Nov - 3 Nov
Mercure Hotel Palermo Centro
A seaside terrace with outdoor seating and a view of the sea and a mountain.
A covered outdoor dining area with tables set for a meal, overlooking the sea.
A spacious lobby with a red carpet, wooden flooring, and a large potted plant.
A hotel room with a bed, desk, chair, and a balcony with curtains.

11. Splendid Hotel La Torre

Splendid Hotel La Torre
Partanna - Mondello
United States
Andrei
3.765.778 ₫
4.404.863 ₫ total
includes taxes & fees
2 Nov - 3 Nov
Splendid Hotel La Torre
A hotel lobby with a wooden-framed entrance leading to a dining area with tables and chairs.
A modern interior with a glass table and chairs, a decorative wall, and a sign indicating 'MAQUEDA HALL' and 'CONFERENCE HALL'.
A hotel room with a large bed, a sofa, a chair, and a window with curtains.
The entrance to Hotel Federico II, featuring a checkered floor, a staircase, and a modern light fixture above the entrance.

12. Central Palace Hotel Federico II

Central Palace Hotel Federico II
Politeama
United States
Robin
3.685.270 ₫
4.317.031 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Central Palace Hotel Federico II
A cityscape with a mountain in the background, buildings with balconies, and palm trees.
A spiral staircase with a beige wall and black balusters.
A modern kitchen with red cabinetry, wooden dining tables, and chairs. There are multiple shelves with kitchenware and a central island with a sink.
A reception desk with a man seated behind it, a digital screen, and a shelf with books and a sign.

13. Hotel Garibaldi

Hotel Garibaldi
Politeama
Australia
John
2.493.814 ₫
3.005.703 ₫ total
includes taxes & fees
6 Nov - 7 Nov
Hotel Garibaldi
A multi-story hotel with balconies, palm trees, and a well-maintained garden.
A modern living room with a black sofa, a coffee table, and a TV mounted on the wall. There is a staircase leading to another level.
A modern living room with a large cactus in a woven basket, black sofas, a flat-screen TV mounted on a wooden wall, and a small table with books.
An outdoor seating area with tables and chairs, surrounded by greenery and illuminated by ambient lighting.

14. Casena Dei Colli, Sure Hotel Collection by Best Western

Casena Dei Colli, Sure Hotel Collection by Best Western
Resuttano-San Lorenzo
United Kingdom
Jayne
1.788.493 ₫
2.229.849 ₫ total
includes taxes & fees
2 Nov - 3 Nov
Casena Dei Colli, Sure Hotel Collection by Best Western
A row of tables with white flowers, a glass railing, and a view of buildings in the background.
A restaurant with a central bar area, clear glass tables, and chairs, and various plants and decorations on the walls.
An outdoor patio area with a patterned rug, potted plants, and a seating arrangement.
A red convertible car parked in front of a building with a black door and a sign that reads "Palladium Hotel."

15. Palazzo Natoli Boutique Hotel

Palazzo Natoli Boutique Hotel
Palermo Historical Center
Canada
Sasha
4.061.696 ₫
4.730.372 ₫ total
includes taxes & fees
5 Nov - 6 Nov
Palazzo Natoli Boutique Hotel
A modern restaurant interior with high ceilings, arched windows, and a long dining area with tables and chairs.
A multi-story building with balconies, a central archway, and doors numbered 110, 112, 114, and 116.
A terrace with outdoor seating, a railing, and a view of the building's architecture.
A room with a round table, two chairs, a vase with flowers, a book, and a glass container with a lemon.

16. NH Collection Palermo Palazzo Sitano

NH Collection Palermo Palazzo Sitano
Palermo Historical Center
Mexico
Gustavo Mora
4.475.872 ₫
5.185.966 ₫ total
includes taxes & fees
3 Nov - 4 Nov
NH Collection Palermo Palazzo Sitano
A spacious hallway with a large painting, ornate chandeliers, and a view through a window.
A spacious living room with a piano, multiple armchairs, and a curved staircase.
A building facade with a sign reading "Hotel Cardino Angleste" and decorative ironwork.
A hotel facade with balconies, potted plants, and a sign indicating it is a hotel.

17. Hotel Giardino Inglese

Hotel Giardino Inglese
Libertà
United Kingdom
Allison
4.488.865 ₫
5.200.259 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Hotel Giardino Inglese
A bathroom with a glass-enclosed shower, a sink, and a mirror with a ring light.
The entrance to the Artemisia Palace Hotel with a glass door, a signboard, and a potted plant in front.
A hotel room with a bed, a bedside table, a mirror, and a door leading to a bathroom.
A lobby with white columns, a statue, a reception desk, and a chandelier.

18. Artemisia Palace Hotel

Artemisia Palace Hotel
Politeama
Canada
Christine
3.067.102 ₫
3.636.320 ₫ total
includes taxes & fees
2 Nov - 3 Nov
Artemisia Palace Hotel
A restaurant with a checkered floor, large windows, and a city view.
A modern spa room with a rectangular hot tub, dark textured walls, and a vase with dried branches.
A modern hotel entrance with a sign for the Hotel Plaza Opera.
A rooftop terrace with a checkered floor, two black chairs, a small table with a potted plant, and a view of city buildings and a mountain in the background.

19. Hotel Plaza Opera

Hotel Plaza Opera
Politeama
United States
Susan
4.394.999 ₫
5.097.006 ₫ total
includes taxes & fees
2 Nov - 3 Nov
Hotel Plaza Opera
A rooftop dining area with tables and chairs, overlooking a cityscape with domed buildings and mountains in the background.
A piano on a wooden floor with a patterned rug, a clock, and a small table with a decorative item.
A view through a window with curtains, featuring a building with a clock tower and mountains in the background.
A hotel room with a bed, a desk, a lamp, and a view of a cityscape with domed buildings.

20. Ambasciatori Hotel

Ambasciatori Hotel
Palermo Historical Center
United States
Hadia
3.033.384 ₫
3.599.230 ₫ total
includes taxes & fees
5 Nov - 6 Nov
Ambasciatori Hotel
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Palermo.
Rocco Forte Villa Igiea

Rocco Forte Villa Igiea

Salita Belmonte 43 Palermo PA
21.212.586 ₫
23.721.859 ₫ total
4 Nov - 5 Nov
includes taxes & fees
9.6/10 Exceptional! (132 reviews)
Rocco Forte Villa Igiea
Grand Hotel et Des Palmes

Grand Hotel et Des Palmes

Via Roma 398 Palermo PA
12.159.402 ₫
13.667.016 ₫ total
6 Nov - 7 Nov
includes taxes & fees
Grand Hotel et Des Palmes
Grand Hotel Wagner

Grand Hotel Wagner

Via R. Wagner, 2 Palermo PA
5.707.480 ₫
6.569.960 ₫ total
3 Nov - 4 Nov
includes taxes & fees
9/10 Wonderful! (896 reviews)
Grand Hotel Wagner
Still don't see what you're looking for?
See all properties in Palermo.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Palermo

Wander through vibrant markets where vendors call out as you sample Sicily's best street food at Ballarò and Vucciria. Ancient Arab-Norman palaces and Byzantine mosaics await exploration, while the golden beaches of Mondello offer perfect afternoon escapes from the city.

See all hotels in Palermo
A historic cathedral with intricate architecture, a large dome, and a bell tower.

Top Palermo Hotel Reviews

Hotel Politeama

Hotel Politeama

10/10 Excellent
"Great location and hotel!"
Daisy 3-night trip
Posted 9 hours ago
Hotel Politeama
Splendid Hotel La Torre

Splendid Hotel La Torre

10/10 Excellent
"the sea access was divine"
Hope 5-night trip
Posted 2 days ago
Splendid Hotel La Torre
Grand Hotel Piazza Borsa

Grand Hotel Piazza Borsa

10/10 Excellent
"If you are looking for old-world charm, this fabulous hotel has it in spades. This is every bit a 5 star hotel. The rooms are spacious, beautifully decorated, and the staff is impeccable. Attention to detail is the rule. Breakfast was fabulous and the lobby is a wonderful place to relax and have a drink after a night out. At first the neighborhood seemed a bit on the gritty side, but that seems to be much less of an issue after we got the hang of things and were more comfortable. We think this hotel is awesome."
Thomas 2-night trip
Posted 3 days ago
Grand Hotel Piazza Borsa
President Hotel Palermo

President Hotel Palermo

8/10 Good
"Hotel was nice, and provided a place to see most of downtown Palermo. Breakfast was typical Italian buffet."
Jeffrey 2-night trip
Posted 9 days ago
President Hotel Palermo
Hotel Plaza Opera

Hotel Plaza Opera

10/10 Excellent
"Close to historical center, nice staff, good breakfast."
Susan 1-night trip
Posted 3 weeks ago
Hotel Plaza Opera
Astoria Palace Hotel

Astoria Palace Hotel

8/10 Good
"It would be nice to have tea, coffe, or hot chocolate making facilities in the room."
Edward 5-night trip
Posted 1 month ago
Astoria Palace Hotel

Frequently asked questions

What are the best 4-star hotels in Palermo?
If you're seeking luxury comfort and loads of amenities on your Palermo holiday, consider Quintocanto Hotel and Spa. This popular 4-star hotel comes with spa facilities and treatment rooms. Eurostars Centrale Palace also gets great reviews from Expedia travellers. Spa facilities and beauty services are among its conveniences.
How much does it cost to stay in a 4-star hotel in Palermo?
We can help you quickly locate the ideal 4-star hotel for your holiday in Palermo. Use our filter tool to tailor your search by things like amenities, budget and property star rating and get access to fantastic deals in a couple of clicks.
  • Search for the lowest price from 6.569.960 ₫
What's the difference between 5-star and 4-star hotels in Palermo?
Treat yourself to luxury during your Palermo holiday by staying at a 4-star hotel. As well as featuring upmarket accommodation, these properties are usually packed with amenities like large beds, bathrobes and more. A 5-star hotel will go the extra mile to make your stay an even more indulgent and memorable one. 24-hour front desk, elegant décor and gourmet dining are a few of the superior services and conveniences you'll likely get access to.

Explore a world of travel with Expedia