Compare and book 4 Star hotels in Santa Cruz, Santa Cruz

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Check availability on Santa Cruz 4 Star Hotels

Tonight
22 Nov - 23 Nov
Tomorrow
23 Nov - 24 Nov
Next weekend
28 Nov - 30 Nov
In two weeks
5 Dec - 7 Dec

Top Santa Cruz 4 Star Hotels

Indoor pool, outdoor pool, pool umbrellas
Camino Real Hotel

Camino Real Hotel

4.5 star property
Santa Cruz
8.8 out of 10, Excellent, (406)
"The parrots. Unique"
United States
Juan P
The price is 3.321.612 ₫
3.321.612 ₫ total
10 Dec - 11 Dec
Camino Real Hotel
Outdoor pool, open 9:00 AM to 10:00 PM, free pool cabanas
TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz

4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (142)
"Nice stay with good service "
United States
Jianyuan
The price is 1.826.887 ₫
1.826.887 ₫ total
1 Dec - 2 Dec
TRYP by Wyndham Santa Cruz
Lounge
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (253)
"Nice hotel "
United States
Narciso Lorenzo
The price is 1.687.168 ₫
1.687.168 ₫ total
29 Nov - 30 Nov
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Massages
Swissôtel Santa Cruz De La Sierra

Swissôtel Santa Cruz De La Sierra

4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (79)
"Beautiful hotel"
Australia
Joanna
The price is 2.731.103 ₫
2.731.103 ₫ total
7 Dec - 8 Dec
Swissôtel Santa Cruz De La Sierra
Junior Single Room | Egyptian cotton sheets, premium bedding, in-room safe, desk
Hotel Maywa

Hotel Maywa

4.0 star property
Santa Cruz
9.4 out of 10, Exceptional, (11)
"The structure and service was fantastic"
United States
Alex
Hotel Maywa
Aerial view
Buganvillas Hotel Suites & Spa

Buganvillas Hotel Suites & Spa

4.0 star property
Santa Cruz
7.4 out of 10, Good, (93)
"The correct description would be that it is a Air & B without a Stowe/owen/kitchen supplies but with a refrigerator. What they claim at the web page IS NOT correct. The pool is correct and there is a restaurant, a one man show. We were the only ones at breakfast, one day no one was even there. A scam. Majority are residents in this complex. The ladies at the receptions was sweet though and did their best. "
Sweden
Charlotte
Buganvillas Hotel Suites & Spa
Front of property – evening/night
Royal Lodge Hotel

Royal Lodge Hotel

4.5 star property
Santa Cruz
6.4 out of 10, (29)
"Esta cerrado, ya no deberia dejar reservar, se nota q tiene tiempo fuera de servicio."
Argentina
Anonymous traveller
Royal Lodge Hotel
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Santa Cruz.
Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel

4to Anillo Entre Radial 23 Santa Cruz Santa Cruz
The price is 2.931.454 ₫ per night from 28 Nov to 29 Nov
2.931.454 ₫
2.931.454 ₫ total
28 Nov - 29 Nov
8.8/10 Excellent! (206 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

See all hotels in Santa Cruz
San Lorenzo Cathedral showing a garden

Top Santa Cruz Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Santa Cruz?
If you're seeking luxury comfort and loads of amenities during your Santa Cruz retreat, consider TRYP by Wyndham Santa Cruz. This 4-star hotel offers a spa tub and a terrace. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia also gets stellar reviews from Expedia guests. Concierge services and a garden are among its conveniences.
How much does it cost to stay in a 4-star hotel in Santa Cruz?
Expedia can help you easily locate the perfect 4-star hotel for your holiday in Santa Cruz. Use our filter tool to tailor your search by things like price, conveniences and star rating and get access to terrific deals in a few clicks.

  • Search for the lowest price from 2.768.010 ₫

What's the difference between 5-star and 4-star hotels in Santa Cruz?
If you choose to spend your holiday at a 4-star hotel in Santa Cruz, you'll typically find plenty of conveniences to ensure you're comfortable, such as a restaurant, gym and pool. You can enjoy top-quality service and deluxe accommodation. Choose a 5-star hotel and you'll get a few extra perks — think concierge assistance, on-site spas and opulent turndown services. You're likely to get more amenities and premium services at a 5-star stay, but both are fabulous options for luxury travellers.

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