Find hotels in Santa Cruz from 1.006.088 ₫

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
29 Nov - 30 Nov
Tomorrow
30 Nov - 1 Dec
Next weekend
5 Dec - 7 Dec
In two weeks
12 Dec - 14 Dec

Filter by

Guest rating
Guest rating
Star rating

Top 10 Santa Cruz hotels and places to stay

Seasonal outdoor pool
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (344)
"Accommodating staff, comfortable rooms, wonderful pool"
Canada
Jay
The price is 3.787.332 ₫
3.787.332 ₫ total
7 Dec - 8 Dec
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Restaurant
Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra

3.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (72)
"Great Spot"
United States
Jose
The price is 1.006.088 ₫
1.006.088 ₫ total
14 Dec - 15 Dec
Ibis Santa Cruz DE LA Sierra
Outdoor pool
Sun Hotel

Sun Hotel

3.5 star property
Santa Cruz
8.4 out of 10, Very good, (329)
"Staff spoke English. Airport pickup beat any US hotel. Rooms nice. Restaurant was ok"
United States
Peter
The price is 2.363.359 ₫
2.363.359 ₫ total
5 Dec - 6 Dec
Sun Hotel
Lounge
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (253)
"Nice hotel "
United States
Narciso Lorenzo
The price is 1.687.360 ₫
1.687.360 ₫ total
6 Dec - 7 Dec
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Reception
Hotel Cortez

Hotel Cortez

3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (120)
"The staff and property are second to none! "
United States
Cynthia
The price is 2.776.234 ₫
2.776.234 ₫ total
30 Nov - 1 Dec
Hotel Cortez
City view from property
HOTEL OSHO

HOTEL OSHO

3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (31)
"Staff is great and place is comfortable "
United States
DITMAR
HOTEL OSHO
Indoor pool, outdoor pool, pool umbrellas
Camino Real Hotel

Camino Real Hotel

4.5 star property
Santa Cruz
8.8 out of 10, Excellent, (406)
"The parrots. Unique"
United States
Juan P
The price is 3.321.990 ₫
3.321.990 ₫ total
25 Dec - 26 Dec
Camino Real Hotel
Outdoor pool, pool umbrellas, pool loungers
Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel

5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (209)
"Great hotel, food and location albeit a little expensive "
United States
Reinaldo
The price is 2.931.788 ₫
2.931.788 ₫ total
5 Dec - 6 Dec
Marriott Santa Cruz de la Sierra Hotel
Exterior
Delfines Collection Hotel By Mercure

Delfines Collection Hotel By Mercure

3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (71)
"Clean comfortable rooms "
United States
mary
The price is 1.225.445 ₫
1.225.445 ₫ total
5 Dec - 6 Dec
Delfines Collection Hotel By Mercure
Business Apartment, Terrace (Plus) | Terrace/patio
Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz

3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (93)
"Come and go easily, intellectual and kind owners who are working hard to make the property improvements that will bring this hotel up to the next level. A family friendly environment with easy walking distance to everything you need. Bed was not the best, but I know they are upgrading so I appreciate the ongoing process. For a few nights stay, the deals are very fair prices. "
United States
Andrew
Apart Hotel Premium Suites Santa Cruz
Exterior
Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra

5.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (103)
"Great location and very clean hotel. Will stay again soon."
United States
William
The price is 2.491.492 ₫
2.491.492 ₫ total
14 Dec - 15 Dec
Novotel Santa Cruz De La Sierra
Reception
Lido Hotel

Lido Hotel

3.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (30)
"Very helpful and nice staff. Quiet location. near the central plaza. Great value "
United Kingdom
David
The price is 1.207.582 ₫
1.207.582 ₫ total
5 Dec - 6 Dec
Lido Hotel
Triple Room | Free WiFi
Hotel Las Américas

Hotel Las Américas

3.0 star property
Santa Cruz
6.0 out of 10, (1)
"O chuveiro foi impossível tomar um.banho de qualidade "
Brazil
Jean
The price is 1.013.207 ₫
1.013.207 ₫ total
11 Dec - 12 Dec
Hotel Las Américas
Front of property
Chairú Eco Hotel

Chairú Eco Hotel

3.5 star property
Santa Cruz
9.6 out of 10, Exceptional, (45)
"Nice property. Would definitely stay there again and again. Only negative was on our last night there was a really noisy party next door that lasted until 2am. "
United States
Andrew
Chairú Eco Hotel
Outdoor pool, open 9:00 AM to 8:00 PM, pool loungers
Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol

3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (78)
"Good price, great hotel!"
United States
James
The price is 1.028.235 ₫
1.028.235 ₫ total
3 Dec - 4 Dec
Premium Suites Deluxe Aparthotel Equipetrol
Outdoor pool, open 9:00 AM to 10:00 PM, free pool cabanas
TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz

4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (144)
"Nice stay with good service "
United States
Jianyuan
The price is 2.011.649 ₫
2.011.649 ₫ total
30 Nov - 1 Dec
TRYP by Wyndham Santa Cruz
Standard Room, 2 Single Beds | Premium bedding, minibar, in-room safe, desk
Hotel LP Santa Cruz Centro

Hotel LP Santa Cruz Centro

3.0 star property
Santa Cruz
8.0 out of 10, Very good, (280)
"Clean, friendly staff"
United States
Giovanna
Hotel LP Santa Cruz Centro
Porch
Hotel Arenal

Hotel Arenal

3.5 star property
Santa Cruz
7.6 out of 10, Good, (59)
"Perfect hotel in a central location!"
United States
Max
The price is 1.842.914 ₫
1.842.914 ₫ total
30 Nov - 1 Dec
Hotel Arenal
Massages
Swissôtel Santa Cruz De La Sierra

Swissôtel Santa Cruz De La Sierra

4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (80)
"Beautiful hotel"
Australia
Joanna
The price is 2.389.988 ₫
2.389.988 ₫ total
19 Dec - 20 Dec
Swissôtel Santa Cruz De La Sierra
Front of property – evening/night
Hotel LP Equipetrol

Hotel LP Equipetrol

3.5 star property
Santa Cruz
8.2 out of 10, Very good, (201)
"Nice place to stay"
United States
Ricardo
Hotel LP Equipetrol
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Great weekend hotel deals in Santa Cruz

Showing deals for:12 Dec - 14 Dec

Image gallery for Novotel Santa Cruz De La Sierra

Exterior
VIP Access

Novotel Santa Cruz De La Sierra

5.0 star property
Santa Cruz
9.2/10Wonderful (103 reviews)
Member Price available
Price is 3.108.433 ₫
6.216.866 ₫ total
Sign in for Member Price
Novotel Santa Cruz De La Sierra
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Where to stay in Santa Cruz

Find the best Santa Cruz areas for the activities you enjoy most. Learn more about Santa Cruz
Learn more about Santa Cruz

Hamacas

When in Hamacas, you can plan a visit to Santa Cruz Zoo and Las Brisas Shopping Center, some noteworthy sights in the nearby area.

Stay near popular Santa Cruz attractions

Plaza 24 de Septiembre featuring street scenes

Plaza 24 de Septiembre

4.4/5 (70 reviews)
Learn about the local history of Santa Cruz when you spend time at Plaza 24 de Septiembre. While in the area, you can find time to visit its shops.
See properties
San Lorenzo Cathedral showing a church or cathedral and interior views

San Lorenzo Cathedral

4.5/5 (36 reviews)
After visiting San Lorenzo Cathedral, make a plan to see the other sights and activities in Santa Cruz. While in the area, you can find time to visit its shops.
See properties

Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

See all hotels in Santa Cruz
San Lorenzo Cathedral showing a garden

Top Santa Cruz Hotel Reviews

Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz

10/10 Excellent
"Everything is perfect!! "
Guillaume 1-night trip
Posted 1 month ago
Apart Hotel Premium Suites Santa Cruz
Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol

10/10 Excellent
"Great folks with there. Clean rooms."
Gregory 3-night trip
Posted 3 months ago
Premium Suites Deluxe Aparthotel Equipetrol

More cheap stays in Santa Cruz

Amaca Hostal

Amaca Hostal

249 Independencia Santa Cruz Departamento de Santa Cruz
Get rates

Hotels in Santa Cruz with star rating

Frequently asked questions

What's the weather like in Santa Cruz?
The hottest months are usually October and November, with an average temperature of 26°C, while the coldest months are June and July, with an average of 21°C. Average annual precipitation for Santa Cruz is 1208 mm.

Explore a world of travel with Expedia