Compare and book 4 Star hotels in Santee, California

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Santee 4 Star Hotels

Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Santee.
Pendry San Diego

Pendry San Diego

550 J Street San Diego CA
The price is 7.767.940 ₫ per night from 29 Apr to 30 Apr
7.767.940 ₫
10.451.902 ₫ total
29 Apr - 30 Apr
includes taxes & fees
9.2/10 Wonderful! (1,000 reviews)
Still don't see what you're looking for?
See all properties in Santee.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santee

Hikers and nature lovers flock to Mission Trails Regional Park for its 60 miles of scenic trails and stunning views. Santee Lakes Recreation Preserve offers family-friendly fishing, camping, and paddle boating where you'll spot turtles sunning themselves on logs.

See all hotels in Santee

Top Santee Hotel Reviews

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

10/10 Excellent
"I love this hotel, very well run. I'm never disappointed!! See ya'll soon! "
Joanna 2-night trip
Posted 2 hours ago
Marriott Marquis San Diego Marina

Frequently asked questions

What are the best 4-star hotels in Santee?
Expedia guests love staying at Sycuan Casino Resort. From its handy amenities to its welcoming staff, everything about this 4-star hotel in Santee is designed to deliver an unforgettable guest experience.
How much does it cost to stay in a 4-star hotel in Santee?
With Expedia's handy filter tool, bagging a superb deal on a 4-star hotel in Santee just got simpler. Start by entering your chosen travel dates and length of your stay. Then list the results by price and choose the option that best suits your style and budget.

  • Search for the lowest price from 10.451.902 ₫

What's the difference between 5-star and 4-star hotels in Santee?
Offering a welcoming traveller experience and upscale surroundings, 4-star hotels are a wonderful option for your Santee getaway. These kinds of accommodation generally come with lots of useful amenities that make it easy to kick back and relax — think large beds, bathrobes, gyms and pools. Or get a taste of the high life at a 5-star hotel designed to spoil you with high-end perks and amenities. 24-hour front desk, premium toiletries and gourmet dining are typically featured at these deluxe retreats.