Compare and book 4 Star hotels in Upstate South Carolina, South Carolina
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11 Sep - 13 SepNext weekend
18 Sep - 20 SepOur top choices for Upstate South Carolina 4-star hotels
3.946.397 ₫
5.327.023 ₫ total
includes taxes & fees
4 Oct - 5 Oct
2. Grand Bohemian Lodge Greenville, Autograph Collection
Grand Bohemian Lodge Greenville, Autograph CollectionGreenville Downtown
David
9.076.200 ₫
10.283.334 ₫ total
includes taxes & fees
4 Oct - 5 Oct
5.432.537 ₫
6.233.044 ₫ total
includes taxes & fees
20 Sept - 21 Sept
4. Mint House Greenville Downtown by Kasa
Mint House Greenville Downtown by KasaGreenville Downtown
Channell
3.485.661 ₫
3.949.253 ₫ total
includes taxes & fees
21 Sept - 22 Sept
3.163.704 ₫
3.584.476 ₫ total
includes taxes & fees
11 Oct - 12 Oct
6.197.748 ₫
6.879.502 ₫ total
includes taxes & fees
4 Oct - 5 Oct
4.187.472 ₫
4.648.093 ₫ total
includes taxes & fees
15 Sept - 16 Sept
2.958.582 ₫
3.283.769 ₫ total
includes taxes & fees
9 Oct - 10 Oct
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Learn more about Upstate South Carolina
Experience the family-friendly area of Upstate South Carolina—live music, sports teams and sights from Frankie's Fun Park to Conestee Nature Preserve.
See all hotels in Upstate South Carolina
Photo by Visit Greenville, South Carolina
Top Upstate South Carolina Hotel Reviews
The Shepherd Hotel Downtown Clemson
10/10 Excellent
"Absolutely perfect in every way!"
Frequently asked questions
What are the best 4-star hotels in Upstate South Carolina?
Stay at Greenville Marriott and get ready for upscale comfort and plenty of handy amenities. This 4-star hotel in Greer, Upstate South Carolina, is highly recommended by Expedia guests.
How much does it cost to stay in a 4-star hotel in Upstate South Carolina?
Expedia can help you quickly locate the perfect 4-star hotel for your getaway in Upstate South Carolina. Use our handy filter tool to tailor your search by things like amenities, budget and property star rating and get access to fabulous deals in a few clicks.
- Search for the lowest price from 3.283.769 ₫
What's the difference between 5-star and 4-star hotels in Upstate South Carolina?
Offering a friendly guest experience and upmarket décor, 4-star hotels are a wonderful option for your Upstate South Carolina trip. These kinds of accommodation generally come with loads of handy amenities that make it simple to kick back and relax — think large beds, bathrobes, restaurants and pools. Or live the high life at a 5-star hotel designed to pamper with exclusive perks and amenities. Full-service health clubs, premium toiletries and fine dining are typically featured at these deluxe retreats.