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Check availability on Upstate South Carolina 4 Star Hotels

Tonight
4 Jul - 5 Jul
Tomorrow
5 Jul - 6 Jul
This weekend
4 Jul - 6 Jul
Next weekend
11 Jul - 13 Jul

Top Upstate South Carolina 4 Star Hotels

The Shepherd Hotel Downtown Clemson
Superior Room, 2 Queen Beds | 1 bedroom, in-room safe, blackout curtains, soundproofing

The Shepherd Hotel Downtown Clemson

4.0 star property
9.8 out of 10, Exceptional, (612)
"Beautiful property, amazing staff and service, will always be my first pick when in town. "
The price is 4.683.356 ₫
5.198.525 ₫ total
includes taxes & fees
5 Jul - 6 Jul
The Shepherd Hotel Downtown Clemson
Grand Bohemian Lodge Greenville, Autograph Collection
Lobby

Grand Bohemian Lodge Greenville, Autograph Collection

4.0 star property
9.6 out of 10, Exceptional, (351)
"Beautiful property "
The price is 6.340.642 ₫
6.974.706 ₫ total
includes taxes & fees
3 Aug - 4 Aug
Grand Bohemian Lodge Greenville, Autograph Collection
The Westin Poinsett Greenville
Exterior

The Westin Poinsett Greenville

4.0 star property
9.2 out of 10, Wonderful, (1000)
"Every person from front desk to wait staff were personable and friendly. Wonderful stay. "
The price is 4.689.979 ₫
5.158.977 ₫ total
includes taxes & fees
3 Aug - 4 Aug
The Westin Poinsett Greenville
Mint House Greenville - Downtown
Apartment, 2 Bedrooms | 3 bedrooms, laptop workspace, iron/ironing board, free WiFi

Mint House Greenville - Downtown

4.0 star property
9.2 out of 10, Wonderful, (679)
"Great place. Will stay again. "
The price is 2.703.943 ₫
3.055.455 ₫ total
includes taxes & fees
3 Aug - 4 Aug
Mint House Greenville - Downtown
Hotel Hartness
Interior entrance

Hotel Hartness

4.0 star property
9.8 out of 10, Exceptional, (544)
"This is a perfect place!! "
The price is 3.728.056 ₫
4.982.913 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Hotel Hartness
Greenville Marriott
1 bedroom, premium bedding, down duvets, pillow-top beds

Greenville Marriott

4.0 star property
8.6 out of 10, Excellent, (574)
"Nice hotel, didn't stay long, just stayed 1 night during a road trip."
The price is 3.427.484 ₫
3.894.512 ₫ total
includes taxes & fees
10 Jul - 11 Jul
Greenville Marriott
The Abernathy of Clemson
Flat-screen TV

The Abernathy of Clemson

4.0 star property
9.6 out of 10, Exceptional, (526)
"Very nice staff, beautiful rooms"
The Abernathy of Clemson
Barsala At The American Spinning Mill Apartments
Apartment, 2 Bedrooms | Living area | 40-inch TV with digital channels

Barsala At The American Spinning Mill Apartments

4.0 star property
8.0 out of 10, Very good, (28)
"Great access to bike trail. No working elevator and 3 flights of stairs with luggage is a challenge. "
Barsala At The American Spinning Mill Apartments
Liberty Hall Bed and Breakfast
Front of property

Liberty Hall Bed and Breakfast

4.0 star property
10.0 out of 10, Exceptional, (65)
"In town for a recent college visit. Great location in a stunning historic BNB. Breakfast was wonderful and customer service was exceptional. Would absolutely recommend staying here and plan to stay again."
Liberty Hall Bed and Breakfast
The Station by Compo Hotels
Trailside Wedge Cottage | Terrace/patio

The Station by Compo Hotels

4.0 star property
10.0 out of 10, Exceptional, (7)
"Beautiful rooms and surroundings. Less than 5 minutes from Furman university and really close to delightful and quirky travelers rest! Great place to stay!"
The price is 5.161.859 ₫
7.839.628 ₫ total
includes taxes & fees
6 Jul - 7 Jul
The Station by Compo Hotels
Hotel Domestique
Fountain

Hotel Domestique

4.0 star property
9.6 out of 10, Exceptional, (29)
"This place is a hidden gem. It is beautiful in every way. The staff is wonderful. The restaurant was incredible. Can’t wait to go back for a longer stay."
The price is 11.224.356 ₫
12.346.792 ₫ total
includes taxes & fees
16 Jul - 17 Jul
Hotel Domestique
Southern Sunshine Retreat
42-inch flat-screen TV with digital channels

Southern Sunshine Retreat

4.0 star property
Southern Sunshine Retreat
Lake Hartwell Frank Howard Home Clemson
Signature House, 4 Bedrooms, Patio | Living room | 43-inch Smart TV with cable channels, TV, fireplace

Lake Hartwell Frank Howard Home Clemson

4.0 star property
The price is 6.227.032 ₫
15.192.912 ₫ total
includes taxes & fees
3 Aug - 4 Aug
Lake Hartwell Frank Howard Home Clemson
Belvedere
Family House, 4 Bedrooms, Patio, Courtyard View | Bathroom | Combined shower/bathtub, free toiletries, hair dryer, bidet

Belvedere

4.0 star property
8.0 out of 10, Very good, (1)
"Bring everything. Including hangers for your clothes, salt and pepper, etc. it is like staying at a place that has one purpose, to rent out. Beds are uncomfortable. Nice big closets with one wire hanger. Why??? "
Belvedere
228 Lakeland
Dock

228 Lakeland

4.0 star property
228 Lakeland
140 Catlin Circle
House | Exterior

140 Catlin Circle

4.0 star property
140 Catlin Circle
Randall St , 202/204
House (202 / 204 Randall St Full Duplex) | Private kitchen | Coffee/tea maker, high chair, blender, cookware/dishes/utensils

Randall St , 202/204

4.0 star property
Randall St , 202/204
34 Allen St
Stovetop, dishwasher, coffee/tea maker, toaster

34 Allen St

4.0 star property
34 Allen St
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Learn more about Upstate South Carolina

Experience the family-friendly area of Upstate South Carolina—live music, sports teams and sights from Discovery Island Water Park to Frankie's Fun Park.

See all hotels in Upstate South Carolina
Greenville - Spartanburg which includes views, tranquil scenes and mountains
Photo by South Carolina Department of Parks, Recreation & Tourism
Open Photo by South Carolina Department of Parks, Recreation & Tourism

Frequently asked questions

What are the best 4-star hotels in Upstate South Carolina?
Stay at Greenville Marriott and get ready for upscale comfort and plenty of handy amenities. This 4-star hotel in Greer, Upstate South Carolina, is highly recommended by Expedia guests.
How much does it cost to stay in a 4-star hotel in Upstate South Carolina?
Expedia can help you quickly locate the perfect 4-star hotel for your getaway in Upstate South Carolina. Use our handy filter tool to tailor your search by things like amenities, budget and property star rating and get access to fabulous deals in a few clicks.

  • Search for the lowest price from 2.703.943 ₫

What's the difference between 5-star and 4-star hotels in Upstate South Carolina?
Offering a friendly guest experience and upmarket décor, 4-star hotels are a wonderful option for your Upstate South Carolina trip. These kinds of accommodation generally come with loads of handy amenities that make it simple to kick back and relax --- think large beds, bathrobes, restaurants and pools. Or live the high life at a 5-star hotel designed to pamper with exclusive perks and amenities. Full-service health clubs, premium toiletries and fine dining are typically featured at these deluxe retreats.