Upstate South Carolina Holiday Rentals, South Carolina: Private House Rentals

A bench, a bicycle, and a lake surrounded by trees.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Upstate South Carolina

Family friendly

Cabin

Waterpark

Spa

Pet friendly

Apartment

Cottage

Pool

Hot tub

Condo

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Upstate South Carolina hotels

A modern hotel room with a large bed, a separate bathroom with a bathtub, a nightstand, a lamp, and a wall-mounted artwork.

A reception area with two beige armchairs, a glass-top table, and a vibrant geometric wall art.

A reception desk with a stone facade, a peacock wall decoration, and a large potted plant.

A Days Inn by Wyndham hotel with a covered entrance, multiple windows, and a parking area with cars.

1. Days Inn by Wyndham Greenville South/Mauldin

Mauldin

David

1.900.088 ₫

2.090.097 ₫ total

includes taxes & fees

13 Sept - 14 Sept

A multi-level hotel atrium with a central open area, multiple balconies, and a variety of seating arrangements.

A multi-level atrium with a modern design, featuring a central open space with tiered seating and tables, surrounded by balconies with greenery.

A modern living room with a dining table, chairs, a sofa, a television, and bookshelves.

An outdoor patio with a stone fire pit, wicker chairs, and a pergola structure.

2. Embassy Suites Greenville Golf Resort & Conference Center

Greenville

Pedro

2.664.283 ₫

3.018.632 ₫ total

includes taxes & fees

20 Sept - 21 Sept

An indoor swimming pool with a tiled floor, a covered area, and a seating area with chairs.

A modern restaurant with high ceilings, large windows, and a mix of seating options including booths and tables.

A fitness center with treadmills, elliptical machines, and a red exercise ball.

A modern hotel lobby with a wooden cabinet, a flat-screen TV, a sofa, and a table.

3. Drury Inn & Suites Greenville

Greenville

Gohan

2.988.935 ₫

3.287.828 ₫ total

includes taxes & fees

14 Sept - 15 Sept

A modern lounge area with a blue sofa, a round coffee table, a patterned ottoman, and a wooden reception desk.

A gym with treadmills, stationary bikes, and exercise balls.

A vending area with various snack and drink options, including chips, sodas, and bottled water.

A modern lobby with a blue sofa, a round coffee table, and a brown armchair.

4. Fairfield Inn & Suites by Marriott Greenville Simpsonville

Simpsonville

Simone

2.076.841 ₫

2.284.785 ₫ total

includes taxes & fees

13 Sept - 14 Sept

A modern hotel room with a large bed, a desk with a chair, a small table, and a nightstand with a lamp.

A Holiday Inn Express & Suites hotel with a modern architectural design, featuring a prominent entrance with columns and a flat roof.

A coffee station with two coffee machines, a coffee press, and various coffee pods and cups.

A gym with exercise equipment, a mirror, and a blue wall.

5. Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Anderson

Merret

2.670.996 ₫

2.964.803 ₫ total

includes taxes & fees

11 Oct - 12 Oct

A multi-story hotel with a modern design, featuring a prominent 'La Quinta' sign, a parking lot, and a landscaped entrance area.

A La Quinta hotel with a covered outdoor seating area, stone pillars, and a parking lot.

A modern kitchen with a refrigerator, coffee machine, and various food items.

A reception area with marble reception desks, a cityscape poster, wooden shelving with toiletries, and pendant lighting.

6. La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

Greenville

Jalen

2.105.159 ₫

2.385.145 ₫ total

includes taxes & fees

15 Sept - 16 Sept

A modern lobby with a reception desk, seating area, and a television screen.

A hotel room with two beds, a desk with a lamp, a chair, a patterned rug, and a large window.

A swimming pool with lounge chairs and tables, surrounded by brick buildings and a covered seating area.

A hotel with a covered entrance, brick exterior, and a sign indicating it is a Best Western hotel.

7. Best Western Spartanburg I-26

Spartanburg

Jonathan

2.402.600 ₫

2.666.886 ₫ total

includes taxes & fees

20 Sept - 21 Sept

A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.

A modern living room with a sofa, two armchairs, a coffee table, and a potted plant.

A hotel room with a bed, a sofa, a dining table with chairs, a coffee machine, and a TV mounted on the wall.

A multi-story hotel with a prominent entrance, a parking lot, and a landscaped area with a small tree.

8. The Abernathy of Clemson

Clemson

Robert

4.187.472 ₫

4.648.093 ₫ total

includes taxes & fees

15 Sept - 16 Sept

A modern restaurant interior with round tables and chairs, a kitchen area, and large windows offering a view of parked cars outside.

A pool area with lounge chairs and a sign for Best Western Plus.

A modern kitchen with a central island, three bar stools, pendant lighting, and a decorative flower arrangement.

A reception area with a stone counter, a laptop, and a sign indicating a Chairman's Award.

9. Best Western Plus Greenville I-385 Inn & Suites

Greenville

Sara

1.970.832 ₫

2.167.915 ₫ total

includes taxes & fees

4 Oct - 5 Oct

A spacious lobby with modern furniture, a chandelier, and potted plants.

A bar with a white countertop, multiple bar stools, and shelves stocked with bottles.

10. Hilton Greenville

Greenville

Edward

2.962.682 ₫

3.356.718 ₫ total

includes taxes & fees

20 Sept - 21 Sept

A hotel with a prominent tower, a covered entrance, and a well-lit facade.

A gazebo with a red bench and a small table, surrounded by a fence and trees.

A white van parked under a covered area with a building in the background.

A hotel room with a large bed, a sofa, a round mirror, and a patterned carpet.

11. La Quinta by Wyndham Haywood Mall-Near Greenville Downtown

Greenville

James

1.763.376 ₫

1.939.712 ₫ total

includes taxes & fees

4 Oct - 5 Oct

A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.

A spacious dining area with a long wooden table and patterned upholstered chairs.

An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.

A spacious lobby with a stone fireplace, modern lighting fixtures, and a seating area with sofas and a coffee table.

12. Lakeside Lodge Clemson

Seneca

Christopher

2.826.588 ₫

3.508.859 ₫ total

includes taxes & fees

15 Sept - 16 Sept

An outdoor patio with wicker furniture, a stone fire pit, and a pergola.

A hotel room with a sofa, a desk, a television, a chair, a small cabinet, and a bed.

A modern kitchen with granite countertops, a central island, and a stone backsplash.

A compact kitchen with a refrigerator, microwave, coffee maker, and a flat-screen TV.

13. Staybridge Suites Greenville I-85 Woodruff Road by IHG

Greenville

Jonathan

4.262.852 ₫

4.689.137 ₫ total

includes taxes & fees

13 Sept - 14 Sept

A hotel with a stone facade, multiple windows, and a sign indicating it's a Wyndham hotel.

A hotel room with a bed, a desk with a chair, a television, a window with curtains, and a bedside table with a lamp.

A modern kitchen with a granite countertop, a built-in grill, a microwave, and a coffee maker. There are two framed artworks on the wall and a refrigerator with a built-in ice maker.

A room with a wall-mounted ATM, decorative wall panels, a window with red curtains, and a tiled floor.

14. Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

Greenville

Charles

1.829.503 ₫

2.012.454 ₫ total

includes taxes & fees

4 Oct - 5 Oct

A spacious lobby with seating areas, a reception desk, and a staircase.

A hotel room with a bed, two bedside tables, a TV, a desk, a chair, and a sofa.

A modern cafe with a central island, seating area, and a wall with circular patterns.

A hotel with a modern facade, a prominent green sign, and a flag.

15. Wingate by Wyndham - Greenville-Airport

Greenville

Victoria

2.081.779 ₫

2.289.957 ₫ total

includes taxes & fees

16 Sept - 17 Sept

A multi-story hotel with a modern design, featuring a mix of glass and brick facades, and a parking area with autumn-colored trees.

A hotel room with a large bed, a TV, a desk, and a view of the city through large windows.

A modern hotel lobby with a mix of seating areas, including sofas and tables, and a patterned carpet.

16. Hyatt Place Greenville Downtown

Greenville Downtown

Jason

3.509.055 ₫

3.975.761 ₫ total

includes taxes & fees

20 Sept - 21 Sept

An outdoor patio area with a wooden pergola, barbecue grill, and seating.

A modern building with large windows and a brick facade at a street corner.

A modern hotel lobby with a seating area featuring sofas and round tables, large windows, and a decorative wooden panel.

A modern hotel lobby with a reception desk, a large round rug, a sofa, and a unique chandelier.

17. Homewood Suites by Hilton Greenville Downtown

Greenville Downtown

Michael

4.113.132 ₫

4.660.179 ₫ total

includes taxes & fees

13 Sept - 14 Sept

A spacious living room with a fireplace, large windows, and a flat-screen TV mounted above the mantel.

A hotel lobby with a reception desk, potted plants, and a tiled floor.

A seating area with wicker chairs, a coffee table, and a large floor lamp.

A multi-story hotel with a prominent entrance, a well-lit facade, and a parking area in front.

18. Hilton Garden Inn Anderson

Anderson

David

2.743.087 ₫

3.044.827 ₫ total

includes taxes & fees

24 Sept - 25 Sept

A hotel room with a sofa, a coffee table, a TV, a desk, and a bed.

A waiting area with leather chairs, a coffee table, a potted plant, and a TV mounted on the wall.

A modern hotel with a covered entrance, stone facade, and well-maintained landscaping.

A spacious dining area with a long table and multiple chairs, a kitchen area with a counter and appliances, and a tiled floor.

19. Best Western Plus Greenville South

Piedmont

Jennifer

2.618.095 ₫

2.906.086 ₫ total

includes taxes & fees

13 Sept - 14 Sept

A reception desk with a modern design, featuring a light wood finish and illuminated panels.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A hotel room with a large bed, a desk with a chair, a TV, and a window with blinds.

An outdoor patio area with tables and chairs, a building with large windows, and a clear sky.

20. Holiday Inn Express & Suites Greenville SE - Simpsonville by IHG

Simpsonville

Alicia

3.327.104 ₫

3.659.814 ₫ total

includes taxes & fees

11 Sept - 12 Sept

View all properties

Holiday Rentals in Upstate South Carolina

Aparthotel

A modern hotel with a sign reading "apt suites" and a parking lot with cars.

An outdoor patio with a stone barbecue grill and white Adirondack chairs.

stayAPT Suites Greenville-Haywood Mall

Greenville

"The rooms are spacious and feels like a and apartment. This place is one of the best places to stay."

Apartment

A modern living room with a sofa, a coffee table, a TV, and a balcony with a view of buildings.

A modern kitchen with white cabinets, a stainless steel refrigerator, and a bar area with white stools.

A bedroom with a bed, bedside tables, a ceiling fan, and two windows with blinds.

A modern kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, and a granite countertop. There are three white bar stools and two pendant lights.

Mint House Greenville Downtown by Kasa

Greenville Downtown

"The unit was very clean, and I stay here whenever I'm in Greenville."

Cabin

A spacious porch with wooden flooring, a dining area with a table and chairs, and a view of the surrounding landscape.

A modern bedroom with a large bed, a ceiling fan, and a view of the outdoors through a window.

A spacious living room with a dark leather sofa, a wooden coffee table, and a dining area with a table and chairs. Large windows provide natural light and views of the outdoors.

A modern kitchen with white cabinets, a large TV, wooden flooring, and a dining area with a bench and coffee table.

Carolina Camp Cedar

Pickens

"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"

Cottage

A house with a grey siding exterior, a white front door, and a window with a white frame.

A living room with a striped sofa, a patterned armchair, and a dark sofa with a floral pillow. There is a wooden coffee table with a book and a plant. A lamp is on a side table next to the sofa.

A dining area with a round table and six chairs, a kitchen with white cabinets, and a window with blinds.

A living room with a brown sofa, a wooden coffee table, a fireplace, a television mounted above the fireplace, and a window with blinds.

Cozy Greenville Bungalow ~ 2 Mi to Downtown!

Greenville

"Amazing place. Great host. "

Aparthotel

A modern building with outdoor seating and a garden.

A modern kitchen with white cabinetry, a wooden dining table, and a black chair. There is a window with a view of greenery outside.

A modern living room with a sofa, coffee table, and dining table. There is a TV mounted on the wall, a coffee machine, and a bookshelf.

A row of modern, two-story buildings with a covered patio area.

The Station by Compo Hotels

Travelers Rest

"Lovely place to stay. Very clean and well appointed. The host was responsive and welcoming. Comfortable bed and quiet. Highly recommend."

Cabin

A wooden interior with a table, chair, and a hanging lantern.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Seneca

"Me and my family had a great time"

Cottage

A cozy living room with a fireplace, a dining area with a table and chairs, and a large wooden door.

A bedroom with a bed, bedside tables, a nightstand, a wooden floor, a door, and a wall-mounted shelf.

A room with wooden sliding doors, a small black table with a potted plant, and a circular sign with the words "stay awhile".

Clemson Memorabilia House

Clemson

"We enjoyed our stay, it was the perfect size for our family of four. "

Mobile Home

A wooden dining table with green placemats, surrounded by chairs, in a cabin with large windows and wooden walls.

A cozy cabin interior with wooden walls, a loft bedroom, a dining area, and a sofa with cushions.

A rustic cabin with a porch, wooden steps, and a picnic table.

A wooden interior with a loft bed, a green chair, a wooden table, and a map on the wall.

Carolina Landing RV Resort - Caravan Park

Fair Play

"Very nice stay with friendly staff"

Cottage

A living room with a sofa, a dining table, chairs, a kitchen area, and a view through large windows.

A cozy living room with a sofa, two side tables, a coffee table, and a patterned rug.

A blue house with a wooden deck, a red door, and a fenced backyard with a small garden.

A two-story house with a front porch, a small garden, and a wooden fence.

Greer Guest House < 1 Mi to Park & Downtown Area!

Greer

"Nice place en Greenville area "

Cottage

A living room with a sofa, coffee table, and a dining area with chairs and a table.

A living room with a fireplace, a round wooden table with chairs, a sofa, and a television.

A covered porch with wicker furniture, a round table with a bowl and a cup, and a view of a lush garden.

A bedroom with a bed, bedside tables, a round mirror, and a ceiling fan.

1 Mi to Downtown Greer: Family Home w/ Gazebo!

Greer

"Very cute home close to everything. Super clean and spacious. Well furnished."

Cottage

A bedroom with a wooden bed, a nightstand, a chair, and a view of the outside through a window.

A covered deck with wooden flooring, outdoor furniture, and a barbecue grill.

A spacious kitchen with wooden flooring, white cabinets, and a dining area with a table and chairs.

Home w/ Lake Keowee Access: Sleeps 7, Coffee Bar

Seneca

"The best, perfect "

Cottage

A modern kitchen with white and blue cabinets, stainless steel appliances, and a central island with bar stools.

A spacious living room with a large TV, comfortable seating, and a kitchen area visible through an open archway.

A dining area with a wooden table, chairs, and a chandelier. There is a view of a kitchen and a balcony with a railing.

A compact room with a bed, a washing machine, and a mirror.

4 Seasons of Fun! Walhalla Home w/ Spacious Yard!

Walhalla

"The house was perfect for our group for our golf trip. We had one minor issue and we were able to speak to the host and they had someone to correct it quickly so that it didn’t disrupt our trip in any way. Place was clean, peaceful, with great hosts."

Apartment

A wooden gazebo with a roof, surrounded by trees, overlooking a lake.

A marina with boats docked, a lifeguard station, and a dock with lounge chairs.

A spacious living area with a high ceiling, wooden beams, a grey sofa, a brown leather chair, and a dining table with a plant.

A modern kitchen with stainless steel appliances, a granite countertop, and large windows offering a view of the outdoors.

Designer Retreat w/ Pool, Golf + Beach Access!

Salem

"Property is in a great community, and it was very clean and beautifully decorated."

Cottage

A cozy cabin interior with a dining area, kitchen, and living space.

A cozy wooden cabin bedroom with a bed, dresser, and ceiling fan.

A wooden cabin kitchen with a granite countertop, stainless steel appliances, and a clock on the wall.

A wooden deck with a railing, a table, and a fish sculpture.

Waterfront Seneca Cabin ~ 4 Mi to Boat Launch!

Seneca

"Beautiful and quaint cabin! Highly recommend, great view of the lake."

Cottage

A white house with a sloped roof, surrounded by trees and a garden.

Clemson Game Day Cottage w/ Fire Pit

Clemson

See all holiday rentals

Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Upstate South Carolina attractions

A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Clemson University

9.6/10 (1,439 reviews)

Take a campus tour or just explore the area of Clemson University during your travels in Clemson. Experience the area's theatre scene or attend a football match.

See properties

A pedestrian bridge with colorful lights, surrounded by trees and a distant building.

Falls Park on the Reedy

9.6/10 (2,661 reviews)

Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theatre scene or attend a sporting event in this family-friendly area.

See properties

Bon Secours Wellness Arena

8.6/10 (1,219 reviews)

Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area.

See properties

Greenville Convention Center

8.4/10 (571 reviews)

Learn about the events happening in Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.

See properties

Memorial Stadium

9.6/10 (410 reviews)

Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theatre scene or attend a football match.

See properties

BMW Performance Center

9.0/10 (90 reviews)

You can spend an afternoon exploring the galleries in BMW Performance Center in Greer. While in this family-friendly area, you can savour the cosy cafes.

See properties

Haywood Mall

8.8/10 (1,681 reviews)

During your trip to Greenville, you can find the perfect gifts to bring home at Haywood Mall. Experience the great live music or attend a sporting event in this family-friendly area.

See properties

Learn more about Upstate South Carolina

Experience the family-friendly area of Upstate South Carolina—live music, sports teams and sights from Frankie's Fun Park to Conestee Nature Preserve.

See all hotels in Upstate South Carolina

An aerial view of a park with a winding path, trees in autumn colors, and a bridge.

Top Upstate South Carolina Hotel Reviews

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

10/10 Excellent

"I’m"

Hyatt Place Greenville Downtown

10/10 Excellent

"Staff great, location great."

Hilton Greenville

10/10 Excellent

"Faster elevators"

Hyatt Regency Greenville

10/10 Excellent

"Great location"

Best Western Plus Clemson Hotel & Conference Center

10/10 Excellent

"Very good breakfast and area! Good staff and clean rooms! Loved it!"

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

8/10 Good

"The place is clean, well run and managed. I very much recommend this hotel."

The Shepherd Hotel Downtown Clemson

10/10 Excellent

"Absolutely perfect in every way!"

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

10/10 Excellent

"A unique experience, cabin provided everything needed except a mirror!! Close enough to town to get to stores and restaraunts easily but loved being far enough in the woods to enjoy the nature."

The Abernathy of Clemson

10/10 Excellent

"Perfect hotel on Clemson’s campus. Walkable to all campus activities and nightlife. Large rooms with a sitting area, kitchenette and walk-in shower."

More cheap stays in Upstate South Carolina

WoodSpring Suites Spartanburg - Duncan

255 Frontage Rd. Duncan SC

1.659.648 ₫

1.867.104 ₫ total

20 Sept - 21 Sept

includes taxes & fees

Best Western Plus Greenville I-385 Inn & Suites

831 Congaree Rd Greenville SC

1.970.832 ₫

2.167.915 ₫ total

4 Oct - 5 Oct

includes taxes & fees

Comfort Inn Greenville - Haywood Mall

246 Congaree Road Greenville SC

2.100.234 ₫

2.388.238 ₫ total

27 Sept - 28 Sept

includes taxes & fees

Best Western Plus Clemson Hotel & Conference Center

1310 Tiger Blvd Clemson SC

2.623.022 ₫

2.911.555 ₫ total

24 Sept - 25 Sept

includes taxes & fees

Comfort Inn & Suites Clemson - University Area

1305 Tiger Blvd Clemson SC

2.733.233 ₫

3.033.887 ₫ total

4 Oct - 5 Oct

includes taxes & fees

Lakeside Lodge Clemson

13500 Clemson Blvd Seneca SC

2.826.588 ₫

3.508.859 ₫ total

15 Sept - 16 Sept

includes taxes & fees

9/10 Wonderful! (1,017 reviews)

Hotels in Upstate South Carolina with star rating

Explore a world of travel with Expedia

More ways to book

Book Hotels in Upstate South Carolina on Expedia.com

Find hotels in Upstate South Carolina, SC from 1.867.104 ₫

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Upstate South Carolina

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Upstate South Carolina hotels

1. Days Inn by Wyndham Greenville South/Mauldin

2. Embassy Suites Greenville Golf Resort & Conference Center

3. Drury Inn & Suites Greenville

4. Fairfield Inn & Suites by Marriott Greenville Simpsonville

5. Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

6. La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

7. Best Western Spartanburg I-26

8. The Abernathy of Clemson

9. Best Western Plus Greenville I-385 Inn & Suites

10. Hilton Greenville

11. La Quinta by Wyndham Haywood Mall-Near Greenville Downtown

12. Lakeside Lodge Clemson

13. Staybridge Suites Greenville I-85 Woodruff Road by IHG

14. Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

15. Wingate by Wyndham - Greenville-Airport

16. Hyatt Place Greenville Downtown

17. Homewood Suites by Hilton Greenville Downtown

18. Hilton Garden Inn Anderson

19. Best Western Plus Greenville South

20. Holiday Inn Express & Suites Greenville SE - Simpsonville by IHG

Holiday Rentals in Upstate South Carolina

stayAPT Suites Greenville-Haywood Mall

Mint House Greenville Downtown by Kasa

Carolina Camp Cedar

Cozy Greenville Bungalow ~ 2 Mi to Downtown!

The Station by Compo Hotels

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Clemson Memorabilia House

Carolina Landing RV Resort - Caravan Park

Greer Guest House < 1 Mi to Park & Downtown Area!

1 Mi to Downtown Greer: Family Home w/ Gazebo!

Home w/ Lake Keowee Access: Sleeps 7, Coffee Bar

4 Seasons of Fun! Walhalla Home w/ Spacious Yard!

Designer Retreat w/ Pool, Golf + Beach Access!

Waterfront Seneca Cabin ~ 4 Mi to Boat Launch!

Clemson Game Day Cottage w/ Fire Pit

Stay near popular Upstate South Carolina attractions

Clemson University

Falls Park on the Reedy

Bon Secours Wellness Arena

Greenville Convention Center

Memorial Stadium

BMW Performance Center

Haywood Mall

Learn more about Upstate South Carolina

Top Upstate South Carolina Hotel Reviews

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Hyatt Place Greenville Downtown

Hilton Greenville

Hyatt Regency Greenville

Best Western Plus Clemson Hotel & Conference Center

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

The Shepherd Hotel Downtown Clemson

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

The Abernathy of Clemson

More cheap stays in Upstate South Carolina

WoodSpring Suites Spartanburg - Duncan

Best Western Plus Greenville I-385 Inn & Suites

Comfort Inn Greenville - Haywood Mall

Best Western Plus Clemson Hotel & Conference Center

Comfort Inn & Suites Clemson - University Area

Lakeside Lodge Clemson

Hotels in Upstate South Carolina with star rating

Explore a world of travel with Expedia

Go further with the Expedia app