Photo by Jeff White

Compare and book 4 Star hotels in Uptown, Collinsville

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Uptown 4 Star Hotels

Tonight
23 Nov - 24 Nov
Tomorrow
24 Nov - 25 Nov
Next weekend
28 Nov - 30 Nov
In two weeks
5 Dec - 7 Dec

Top Uptown 4 Star Hotels

Bar (on property)
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1119)
"Really nice hotel!"
United States
DARIN
The price is 2.662.562 ₫
3.166.559 ₫ total
includes taxes & fees
26 Nov - 27 Nov
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Lobby
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (4005)
"Loved our stay. Great location and awesome view from room "
United States
Phillip
The price is 2.491.209 ₫
2.937.858 ₫ total
includes taxes & fees
26 Nov - 27 Nov
Hyatt Regency St. Louis at The Arch
Interior
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1470)
"Great staff and clean room"
United States
Chris
The price is 3.772.402 ₫
4.542.842 ₫ total
includes taxes & fees
30 Nov - 1 Dec
21C Museum Hotel St Louis
Terrace/patio
The Cheshire

The Cheshire

4.0 star property
Richmond Heights
8.6 out of 10, Excellent, (1006)
"Excellent place to stay. "
United States
Todd
The price is 3.395.162 ₫
4.031.347 ₫ total
includes taxes & fees
30 Nov - 1 Dec
The Cheshire
Terrace/patio
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4.0 star property
Grand Center
8.8 out of 10, Excellent, (1033)
"Very unique and clean, and friendly staff"
United States
Jeremy
The price is 2.920.066 ₫
3.443.604 ₫ total
includes taxes & fees
7 Dec - 8 Dec
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Breakfast, lunch and dinner served
Live by Loews - St.Louis

Live by Loews - St.Louis

4.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1092)
"We had an amazing view of the ballpark! The room and service was great. The restaurant and food room service were delicious! Overall great stay!"
United States
Melissa
The price is 3.927.938 ₫
4.671.457 ₫ total
includes taxes & fees
24 Nov - 25 Nov
Live by Loews - St.Louis
Lounge
The Westin St. Louis

The Westin St. Louis

4.5 star property
Downtown St. Louis
8.6 out of 10, Excellent, (1006)
"Very clean and perfect downtown location..walking distance to so many things. We will definitely stay again!"
United States
Christie
The price is 3.114.670 ₫
3.641.952 ₫ total
includes taxes & fees
29 Nov - 30 Nov
The Westin St. Louis
In-room safe, desk, blackout curtains, iron/ironing board
DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park

4.0 star property
Central West End
8.2 out of 10, Very good, (1001)
"Courteous helpful staff, great room. Perfect location if at Washington University"
United States
Raenette
The price is 3.220.909 ₫
3.798.386 ₫ total
includes taxes & fees
30 Nov - 1 Dec
DoubleTree by Hilton St. Louis Forest Park
Daily cooked-to-order breakfast for a fee
River City Casino & Hotel

River City Casino & Hotel

4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1449)
"Awesome place to stay!!"
United States
Kaitlyn
The price is 2.029.610 ₫
2.744.021 ₫ total
includes taxes & fees
30 Nov - 1 Dec
River City Casino & Hotel
Lobby
St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton

4.0 star property
Downtown West
8.4 out of 10, Very good, (1008)
"Nice historic hotel"
United States
Michelle
The price is 3.739.713 ₫
4.447.603 ₫ total
includes taxes & fees
30 Nov - 1 Dec
St. Louis Union Station Hotel, Curio Collection by Hilton
Exterior
Marriott St. Louis Grand

Marriott St. Louis Grand

4.0 star property
Downtown St. Louis
8.2 out of 10, Very good, (1000)
"Very convenient to the local sites we wanted to visit."
United States
Garland
The price is 3.347.974 ₫
3.981.712 ₫ total
includes taxes & fees
30 Nov - 1 Dec
Marriott St. Louis Grand
Exterior
Moonrise Hotel

Moonrise Hotel

4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (1918)
"This spot is our absolute favorite when visiting StL and stay every chance we get. The surrounding area is amazing and vibrant, the hotel is extremely friendly and inviting and the rooms are great and rich with city history! Can’t wait to get back. "
United States
Brian
The price is 3.319.756 ₫
3.948.153 ₫ total
includes taxes & fees
2 Dec - 3 Dec
Moonrise Hotel
Exterior
Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch

4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1002)
"My second time staying there as always it was lovely "
United States
Nina
The price is 2.720.558 ₫
3.208.325 ₫ total
includes taxes & fees
30 Nov - 1 Dec
Hilton Pennywell St. Louis at the Arch
Outdoor pool, open 8:00 AM to 8:30 PM, pool umbrellas, pool loungers
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

4.0 star property
Clayton
8.8 out of 10, Excellent, (675)
"Small rooms but beautiful lobby. "
United States
Debbie
The price is 3.142.350 ₫
3.699.741 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Le Méridien St. Louis Clayton
Exterior
Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown

4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1240)
"Food was very good and well presented. "
United States
Lorie
The price is 2.826.006 ₫
3.360.941 ₫ total
includes taxes & fees
30 Nov - 1 Dec
Embassy Suites by Hilton St. Louis Downtown
Seasonal outdoor pool
The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

4.5 star property
Central West End
9.0 out of 10, Wonderful, (1004)
"Clean room and staff was great. "
United States
Ronnell
The price is 4.402.454 ₫
5.968.922 ₫ total
includes taxes & fees
29 Nov - 30 Nov
The Royal Sonesta Chase Park Plaza St. Louis
Lobby lounge
AC Hotel St. Louis Central West End

AC Hotel St. Louis Central West End

4.0 star property
Central West End
9.0 out of 10, Wonderful, (676)
"Great staff. Rooms were super clean. 10/10 will stay here again"
United States
Jacob
The price is 3.558.870 ₫
4.196.940 ₫ total
includes taxes & fees
30 Nov - 1 Dec
AC Hotel St. Louis Central West End
Rooftop bar
Hotel Saint Louis, Autograph Collection

Hotel Saint Louis, Autograph Collection

4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (460)
"Everything was definitely worth the stay! "
United States
Briana
The price is 3.374.336 ₫
4.013.064 ₫ total
includes taxes & fees
26 Nov - 27 Nov
Hotel Saint Louis, Autograph Collection
3 bars/lounges, rooftop bar
Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark

4.0 star property
Downtown St. Louis
7.6 out of 10, Good, (1065)
"The front desk staff was very helpful Rikki was the best."
United States
Sherlinda
The price is 3.220.909 ₫
3.830.596 ₫ total
includes taxes & fees
29 Nov - 30 Nov
Hilton St. Louis at the Ballpark
Outdoor pool
The Last Hotel

The Last Hotel

4.5 star property
Downtown West
7.6 out of 10, Good, (1000)
"HaD a great stay "
United States
christine
The Last Hotel
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Uptown.
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO
The price is 11.203.850 ₫ per night from 28 Nov to 29 Nov
11.203.850 ₫
13.100.550 ₫ total
28 Nov - 29 Nov
includes taxes & fees
9.4/10 Exceptional! (1,001 reviews)
Still don't see what you're looking for?
See all properties in Uptown.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Uptown Hotel Reviews

Explore a world of travel with Expedia